tramiprosate has been researched along with Seizures in 4 studies
tramiprosate: GABA receptor agonist and a glycosaminoglycan mimetic; has nootropic acitivity; structure; a sulfonate analog of GABA
3-aminopropanesulfonic acid : An amino sulfonic acid that is the 3-amino derivative of propanesulfonic acid.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Taurine, an inhibitory non-GABA-mimetic amino acid, and muscimol (another direct GABA-agonist) reduced the number of seizures and lesions in the brain but were less effective than homotaurine." | 3.66 | Homotaurine (3 aminopropanesulfonic acid; 3APS) protects from the convulsant and cytotoxic effect of systemically administered kainic acid. ( Fariello, RG; Golden, GT; Pisa, M, 1982) |
| "Homotaurine is a powerful GABA agonist that exerts a central action upon parenteral administration." | 1.26 | Activating effects of homotaurine and taurine on corticoreticular epilepsy. ( Black, JA; Fariello, RG; Golden, GT, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Golden, GT | 3 |
| Fariello, RG | 3 |
| Black, JA | 1 |
| Pisa, M | 1 |
| Bartolini, A | 1 |
| Galli, A | 1 |
| Bartolini, R | 1 |
| Adembri, G | 1 |
| Zilletti, L | 1 |
| Giotti, A | 1 |
4 other studies available for tramiprosate and Seizures
| Article | Year |
|---|---|
Penicillin spikes in rats. Limitations of a simple model for the study of anticonvulsants.
Topics: Action Potentials; Animals; Anticonvulsants; Dimethyl Sulfoxide; Disease Models, Animal; Drug Evalua | 1984 |
Activating effects of homotaurine and taurine on corticoreticular epilepsy.
Topics: Animals; beta-Alanine; Cats; Electrodes, Implanted; Electroencephalography; gamma-Aminobutyric Acid; | 1981 |
Homotaurine (3 aminopropanesulfonic acid; 3APS) protects from the convulsant and cytotoxic effect of systemically administered kainic acid.
Topics: Animals; Anticonvulsants; Brain; Caudate Nucleus; Electroencephalography; Evoked Potentials; Kainic | 1982 |
[Role of 5-hydroxytryptamine and of the acetylocholine in the anticonvulsive action of homotaurine].
Topics: Acetylcholine; Animals; Anticonvulsants; Cerebral Cortex; Male; Rats; Seizures; Serotonin; Taurine | 1975 |