| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Bone Loss, Osteoclastic
[description not available] | 0 | 3.69 | 3 | 0 |
Age-Related Osteoporosis
[description not available] | 0 | 2.97 | 1 | 0 |
Osteoporosis
Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. | 0 | 2.97 | 1 | 0 |
Glial Cell Tumors
[description not available] | 0 | 4.34 | 4 | 1 |
Glioma
Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21) | 0 | 4.34 | 4 | 1 |
Innate Inflammatory Response
[description not available] | 0 | 4.38 | 18 | 0 |
Ache
[description not available] | 0 | 2.97 | 4 | 0 |
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 4.38 | 18 | 0 |
Pain
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS. | 0 | 2.97 | 4 | 0 |
MS (Multiple Sclerosis)
[description not available] | 0 | 3.21 | 5 | 0 |
Cancer of Prostate
[description not available] | 0 | 2.11 | 1 | 0 |
Multiple Sclerosis
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903) | 0 | 3.21 | 5 | 0 |
Prostatic Neoplasms
Tumors or cancer of the PROSTATE. | 0 | 2.11 | 1 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 6.96 | 40 | 0 |
Clerambault Syndrome
[description not available] | 0 | 2.41 | 1 | 0 |
HIV Coinfection
[description not available] | 0 | 2.41 | 1 | 0 |
HIV Infections
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS). | 0 | 2.41 | 1 | 0 |
Blood Poisoning
[description not available] | 0 | 2.85 | 3 | 0 |
Lung Injury, Acute
[description not available] | 0 | 3.54 | 6 | 0 |
Sepsis
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK. | 0 | 2.85 | 3 | 0 |
Acute Lung Injury
A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological). | 0 | 3.54 | 6 | 0 |
Arthritis, Degenerative
[description not available] | 0 | 2.82 | 2 | 0 |
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. | 0 | 7.82 | 2 | 0 |
Infections, Pseudomonas
[description not available] | 0 | 3.33 | 4 | 0 |
Acute Respiratory Distress Syndrome
[description not available] | 0 | 3.33 | 4 | 0 |
Pseudomonas Infections
Infections with bacteria of the genus PSEUDOMONAS. | 0 | 3.33 | 4 | 0 |
Respiratory Distress Syndrome
A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA. | 0 | 3.33 | 4 | 0 |
Becker Muscular Dystrophy
[description not available] | 0 | 2.6 | 1 | 0 |
Cardiomyopathies, Primary
[description not available] | 0 | 2.6 | 1 | 0 |
Cardiomyopathies
A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS). | 0 | 2.6 | 1 | 0 |
Muscular Dystrophy, Duchenne
An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415) | 0 | 2.6 | 1 | 0 |
Alloxan Diabetes
[description not available] | 0 | 2.94 | 3 | 0 |
Autoimmune Diabetes
[description not available] | 0 | 2.76 | 2 | 0 |
Diabetes Mellitus, Adult-Onset
[description not available] | 0 | 2.63 | 2 | 0 |
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. | 0 | 2.76 | 2 | 0 |
Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY. | 0 | 2.63 | 2 | 0 |
Cirrhosis
[description not available] | 0 | 3.21 | 5 | 0 |
Alveolitis, Fibrosing
[description not available] | 0 | 2.69 | 2 | 0 |
Fibrosis
Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury. | 0 | 8.21 | 5 | 0 |
Pulmonary Fibrosis
A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death. | 0 | 7.69 | 2 | 0 |
Injury, Ischemia-Reperfusion
[description not available] | 0 | 3.27 | 5 | 0 |
Reperfusion Injury
Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA. | 0 | 8.27 | 5 | 0 |
Cystitis
Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain. | 0 | 2.25 | 1 | 0 |
Absence Seizure
[description not available] | 0 | 2.66 | 2 | 0 |
Seizures
Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder. | 0 | 2.66 | 2 | 0 |
Brain Inflammation
[description not available] | 0 | 3.03 | 4 | 0 |
Encephalitis
Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition. | 0 | 3.03 | 4 | 0 |
Bowel Diseases, Inflammatory
[description not available] | 0 | 2.51 | 2 | 0 |
Inflammatory Bowel Diseases
Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS. | 0 | 2.51 | 2 | 0 |
Blood Pressure, High
[description not available] | 0 | 2.25 | 1 | 0 |
Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. | 0 | 2.25 | 1 | 0 |
Experimental Spinal Cord Ischemia
[description not available] | 0 | 2.25 | 1 | 0 |
Nerve Pain
[description not available] | 0 | 2.77 | 3 | 0 |
Neuralgia
Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve. | 0 | 2.77 | 3 | 0 |
Aura
[description not available] | 0 | 2.31 | 1 | 0 |
Epilepsy
A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313) | 0 | 2.31 | 1 | 0 |
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 3.74 | 3 | 0 |
Cold Panniculitis
[description not available] | 0 | 2.25 | 1 | 0 |
Obesity
A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY). | 0 | 2.25 | 1 | 0 |
Brain Vascular Disorders
[description not available] | 0 | 2.31 | 1 | 0 |
Cerebrovascular Disorders
A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others. | 0 | 2.31 | 1 | 0 |
Joint Pain
[description not available] | 0 | 2.31 | 1 | 0 |
Arthralgia
Pain in the joint. | 0 | 2.31 | 1 | 0 |
Degenerative Diseases, Central Nervous System
[description not available] | 0 | 3.23 | 1 | 0 |
Child Mental Disorders
[description not available] | 0 | 3.23 | 1 | 0 |
Behavior Disorders
[description not available] | 0 | 3.23 | 1 | 0 |
Mental Disorders
Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function. | 0 | 3.23 | 1 | 0 |
Neurodegenerative Diseases
Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures. | 0 | 3.23 | 1 | 0 |
Neurodevelopmental Disorders
These are a group of conditions with onset in the developmental period. The disorders typically manifest early in development, often before the child enters grade school, and are characterized by developmental deficits that produce impairments of personal, social, academic, or occupational functioning. (From DSM-5). | 0 | 3.23 | 1 | 0 |
Acute Confusional Senile Dementia
[description not available] | 0 | 3.33 | 6 | 0 |
Age-Related Memory Disorders
[description not available] | 0 | 2.83 | 3 | 0 |
Aging
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. | 0 | 2.53 | 2 | 0 |
Alzheimer Disease
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) | 0 | 3.33 | 6 | 0 |
Memory Disorders
Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions. | 0 | 2.83 | 3 | 0 |
Cognition Disorders
Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment. | 0 | 2.51 | 2 | 0 |
Complication, Postoperative
[description not available] | 0 | 2.15 | 1 | 0 |
Segond Fracture
[description not available] | 0 | 2.15 | 1 | 0 |
Postoperative Complications
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. | 0 | 2.15 | 1 | 0 |
Tibial Fractures
Fractures of the TIBIA. | 0 | 2.15 | 1 | 0 |
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 2.55 | 2 | 0 |
Asymmetric Diabetic Proximal Motor Neuropathy
[description not available] | 0 | 2.15 | 1 | 0 |
Allodynia
[description not available] | 0 | 3.31 | 6 | 0 |
Diabetic Neuropathies
Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325) | 0 | 2.15 | 1 | 0 |
Brain Swelling
[description not available] | 0 | 3.37 | 6 | 0 |
Brain Hemorrhage, Cerebral
[description not available] | 0 | 2.86 | 3 | 0 |
Brain Edema
Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6) | 0 | 3.37 | 6 | 0 |
Cerebral Hemorrhage
Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA. | 0 | 2.86 | 3 | 0 |
Cardiac Toxicity
[description not available] | 0 | 2.17 | 1 | 0 |
Tachyarrhythmia
[description not available] | 0 | 2.17 | 1 | 0 |
Tachycardia
Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia. | 0 | 2.17 | 1 | 0 |
Cardiotoxicity
Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION. | 0 | 2.17 | 1 | 0 |
Bone Cancer
[description not available] | 0 | 2.17 | 1 | 0 |
Osteogenic Sarcoma
[description not available] | 0 | 2.17 | 1 | 0 |
Bone Neoplasms
Tumors or cancer located in bone tissue or specific BONES. | 0 | 2.17 | 1 | 0 |
Osteosarcoma
A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed) | 0 | 2.17 | 1 | 0 |
Adjuvant Arthritis
[description not available] | 0 | 2.21 | 1 | 0 |
Hyperactivity, Motor
[description not available] | 0 | 2.21 | 1 | 0 |
Cardiovascular Stroke
[description not available] | 0 | 3.71 | 3 | 0 |
Myocardial Infarction
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). | 0 | 3.71 | 3 | 0 |
Experimental Lung Inflammation
Inflammation of any part, segment or lobe, of the lung parenchyma. | 0 | 2.55 | 2 | 0 |
Pneumonia
Infection of the lung often accompanied by inflammation. | 0 | 2.55 | 2 | 0 |
Panic Attacks
[description not available] | 0 | 2.21 | 1 | 0 |
Panic Disorder
A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait. | 0 | 2.21 | 1 | 0 |
Autoimmune Thrombocytopenia
[description not available] | 0 | 2.21 | 1 | 0 |
Purpura, Thrombocytopenic, Idiopathic
Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms. | 0 | 2.21 | 1 | 0 |
Amyloid Deposits
[description not available] | 0 | 2.75 | 3 | 0 |
Heart Disease, Ischemic
[description not available] | 0 | 2.08 | 1 | 0 |
Myocardial Ischemia
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION). | 0 | 2.08 | 1 | 0 |
Injury, Myocardial Reperfusion
[description not available] | 0 | 2.77 | 3 | 0 |
Ischemia
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION. | 0 | 7.5 | 2 | 0 |
Cruveilhier-Baumgarten Syndrome
Liver cirrhosis with intrahepatic portal obstruction, HYPERTENSION, and patent UMBILICAL VEINS. | 0 | 2.08 | 1 | 0 |
Hypertension, Portal
Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN. | 0 | 2.08 | 1 | 0 |
Osteoarthritis of Knee
[description not available] | 0 | 2.08 | 1 | 0 |
Osteoarthritis, Knee
Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019) | 0 | 2.08 | 1 | 0 |
Elevated Cholesterol
[description not available] | 0 | 2.08 | 1 | 0 |
Impotence
[description not available] | 0 | 2.08 | 1 | 0 |
Hypercholesterolemia
A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population. | 0 | 2.08 | 1 | 0 |
Erectile Dysfunction
The inability in the male to have a PENILE ERECTION due to psychological or organ dysfunction. | 0 | 7.08 | 1 | 0 |
Hemorrhage, Subarachnoid
[description not available] | 0 | 2.8 | 3 | 0 |
Subarachnoid Hemorrhage
Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status. | 0 | 2.8 | 3 | 0 |
Bacterial Disease
[description not available] | 0 | 2.1 | 1 | 0 |
Cirrhoses, Experimental Liver
[description not available] | 0 | 2.1 | 1 | 0 |
Primary Peritonitis
[description not available] | 0 | 2.1 | 1 | 0 |
Ascites
Accumulation or retention of free fluid within the peritoneal cavity. | 0 | 2.1 | 1 | 0 |
Bacterial Infections
Infections by bacteria, general or unspecified. | 0 | 2.1 | 1 | 0 |
Peritonitis
INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs. | 0 | 2.1 | 1 | 0 |
Edema, Pulmonary
[description not available] | 0 | 2.77 | 3 | 0 |
Pulmonary Edema
Excessive accumulation of extravascular fluid in the lung, an indication of a serious underlying disease or disorder. Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening. | 0 | 2.77 | 3 | 0 |
Cardiac Hypertrophy
Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix. | 0 | 2.1 | 1 | 0 |
Cardiomegaly
Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES. | 0 | 2.1 | 1 | 0 |
Acute Brain Injuries
[description not available] | 0 | 2.81 | 3 | 0 |
Brain Injuries
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits. | 0 | 2.81 | 3 | 0 |
Rheumatoid Arthritis
[description not available] | 0 | 3.01 | 1 | 0 |
Arthritis, Rheumatoid
A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. | 0 | 3.01 | 1 | 0 |
Cocaine Abuse
[description not available] | 0 | 2.1 | 1 | 0 |
Cocaine-Related Disorders
Disorders related or resulting from use of cocaine. | 0 | 2.1 | 1 | 0 |
Bruise
[description not available] | 0 | 2.11 | 1 | 0 |
Contusions
Injuries resulting in hemorrhage, usually manifested in the skin. | 0 | 2.11 | 1 | 0 |
Chronic Illness
[description not available] | 0 | 3.69 | 3 | 0 |
Brain Hemorrhage
[description not available] | 0 | 3.04 | 4 | 0 |
Acute Disease
Disease having a short and relatively severe course. | 0 | 2.11 | 1 | 0 |
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 3.69 | 3 | 0 |
Intracranial Hemorrhages
Bleeding within the SKULL, including hemorrhages in the brain and the three membranes of MENINGES. The escape of blood often leads to the formation of HEMATOMA in the cranial epidural, subdural, and subarachnoid spaces. | 0 | 3.04 | 4 | 0 |
Depression, Endogenous
[description not available] | 0 | 2.11 | 1 | 0 |
Depressive Disorder
An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent. | 0 | 2.11 | 1 | 0 |
Acute Hepatic Failure
[description not available] | 0 | 2.11 | 1 | 0 |
Liver Failure, Acute
A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C. | 0 | 2.11 | 1 | 0 |
Allergic Encephalomyelitis
[description not available] | 0 | 2.47 | 2 | 0 |
Endotoxemia
A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators. | 0 | 7.11 | 1 | 0 |
Aggression
Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism. | 0 | 2.11 | 1 | 0 |
Nerve Degeneration
Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways. | 0 | 2.46 | 2 | 0 |
Breast Cancer
[description not available] | 0 | 3.67 | 3 | 0 |
Osteolysis
Dissolution of bone that particularly involves the removal or loss of calcium. | 0 | 2.11 | 1 | 0 |
Breast Neoplasms
Tumors or cancer of the human BREAST. | 0 | 3.67 | 3 | 0 |
Cerebral Infarction, Middle Cerebral Artery
[description not available] | 0 | 3.01 | 4 | 0 |
Infarction, Middle Cerebral Artery
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction. | 0 | 3.01 | 4 | 0 |
Cancer of Lung
[description not available] | 0 | 2.77 | 3 | 0 |
Lung Neoplasms
Tumors or cancer of the LUNG. | 0 | 2.77 | 3 | 0 |
Alcohol Drinking
Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking. | 0 | 2.11 | 1 | 0 |
Apoplexy
[description not available] | 0 | 2.13 | 1 | 0 |
Depression
Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders. | 0 | 2.13 | 1 | 0 |
Stroke
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810) | 0 | 2.13 | 1 | 0 |
Allergic Reaction
[description not available] | 0 | 2.13 | 1 | 0 |
Hypersensitivity
Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen. | 0 | 2.13 | 1 | 0 |
Asthma, Bronchial
[description not available] | 0 | 2.13 | 1 | 0 |
Asthma
A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL). | 0 | 2.13 | 1 | 0 |
Atherogenesis
[description not available] | 0 | 2.49 | 2 | 0 |
Atherosclerosis
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. | 0 | 2.49 | 2 | 0 |
Disease Exacerbation
[description not available] | 0 | 3.42 | 2 | 0 |
Cancer of Colon
[description not available] | 0 | 2.46 | 2 | 0 |
Colonic Neoplasms
Tumors or cancer of the COLON. | 0 | 2.46 | 2 | 0 |
Aqueductal Stenosis
[description not available] | 0 | 2.15 | 1 | 0 |
Colitis
Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER. | 0 | 3.66 | 3 | 0 |
Benign Neoplasms
[description not available] | 0 | 2.96 | 1 | 0 |
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 2.96 | 1 | 0 |
Jejunal Diseases
Pathological development in the JEJUNUM region of the SMALL INTESTINE. | 0 | 2.05 | 1 | 0 |
Ileus
A condition caused by the lack of intestinal PERISTALSIS or INTESTINAL MOTILITY without any mechanical obstruction. This interference of the flow of INTESTINAL CONTENTS often leads to INTESTINAL OBSTRUCTION. Ileus may be classified into postoperative, inflammatory, metabolic, neurogenic, and drug-induced. | 0 | 2.05 | 1 | 0 |
Cerebral Ischemia
[description not available] | 0 | 2.05 | 1 | 0 |
Brain Ischemia
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION. | 0 | 2.05 | 1 | 0 |
Metastase
[description not available] | 0 | 2.05 | 1 | 0 |
Angiogenesis, Pathologic
[description not available] | 0 | 2.95 | 4 | 0 |
Experimental Mammary Neoplasms
[description not available] | 0 | 2.05 | 1 | 0 |
Neoplasm Metastasis
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. | 0 | 2.05 | 1 | 0 |
Acute Liver Injury, Drug-Induced
[description not available] | 0 | 2.05 | 1 | 0 |
Chemical and Drug Induced Liver Injury
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. | 0 | 2.05 | 1 | 0 |
Anxiety
Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS. | 0 | 2.07 | 1 | 0 |
Atheroma
[description not available] | 0 | 2.07 | 1 | 0 |
Carotid Artery Narrowing
[description not available] | 0 | 2.07 | 1 | 0 |
Carotid Stenosis
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3) | 0 | 2.07 | 1 | 0 |
Chemical Dependence
[description not available] | 0 | 2.07 | 1 | 0 |
Substance-Related Disorders
Disorders related to substance use or abuse. | 0 | 2.07 | 1 | 0 |
Carcinoma, Non-Small Cell Lung
[description not available] | 0 | 2.07 | 1 | 0 |
Carcinoma, Non-Small-Cell Lung
A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy. | 0 | 2.07 | 1 | 0 |
Hepatocellular Carcinoma
[description not available] | 0 | 2.08 | 1 | 0 |
Cancer of Liver
[description not available] | 0 | 2.08 | 1 | 0 |
Invasiveness, Neoplasm
[description not available] | 0 | 2.46 | 2 | 0 |
Carcinoma, Hepatocellular
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. | 0 | 2.08 | 1 | 0 |
Liver Neoplasms
Tumors or cancer of the LIVER. | 0 | 2.08 | 1 | 0 |
Anterior Cerebral Circulation Infarction
[description not available] | 0 | 2.07 | 1 | 0 |
Dyskinesia Syndromes
[description not available] | 0 | 2.07 | 1 | 0 |
Movement Disorders
Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions. | 0 | 2.07 | 1 | 0 |
Brain Infarction
Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis. | 0 | 2.07 | 1 | 0 |
Anasarca
[description not available] | 0 | 2.46 | 2 | 0 |
Acute Edematous Pancreatitis
[description not available] | 0 | 2.08 | 1 | 0 |
Edema
Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE. | 0 | 7.46 | 2 | 0 |
Pancreatitis
INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis. | 0 | 2.08 | 1 | 0 |
Intraocular Pressure
The pressure of the fluids in the eye. | 0 | 7.01 | 1 | 0 |
Cancer of Skin
[description not available] | 0 | 2.01 | 1 | 0 |
Skin Neoplasms
Tumors or cancer of the SKIN. | 0 | 2.01 | 1 | 0 |
Experimental Neoplasms
[description not available] | 0 | 2.01 | 1 | 0 |
Cough
A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. | 0 | 2.01 | 1 | 0 |
Peripheral Nerve Diseases
[description not available] | 0 | 2.43 | 2 | 0 |
Peripheral Nervous System Diseases
Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves. | 0 | 2.43 | 2 | 0 |
Myelopathy
[description not available] | 0 | 2.02 | 1 | 0 |
Spinal Cord Diseases
Pathologic conditions which feature SPINAL CORD damage or dysfunction, including disorders involving the meninges and perimeningeal spaces surrounding the spinal cord. Traumatic injuries, vascular diseases, infections, and inflammatory/autoimmune processes may affect the spinal cord. | 0 | 2.02 | 1 | 0 |
Autoimmune Disease Models, Nervous System
[description not available] | 0 | 2.03 | 1 | 0 |
Neuroretinitis
[description not available] | 0 | 2.03 | 1 | 0 |
Retinitis
Inflammation of the RETINA. It is rarely limited to the retina, but is commonly associated with diseases of the choroid (CHORIORETINITIS) and of the OPTIC DISK (neuroretinitis). | 0 | 7.03 | 1 | 0 |
Uveitis
Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed) | 0 | 2.03 | 1 | 0 |
Adenoma, beta-Cell
[description not available] | 0 | 2.03 | 1 | 0 |
Insulinoma
A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA. | 0 | 2.03 | 1 | 0 |
Airway Obstruction
Any hindrance to the passage of air into and out of the lungs. | 0 | 2.03 | 1 | 0 |
Esophageal Reflux
[description not available] | 0 | 2.03 | 1 | 0 |
Extravasation of Contrast Media
[description not available] | 0 | 2.03 | 1 | 0 |
Gastroesophageal Reflux
Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER. | 0 | 2.03 | 1 | 0 |
Cirrhosis, Liver
[description not available] | 0 | 2.04 | 1 | 0 |
Liver Cirrhosis
Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. | 0 | 2.04 | 1 | 0 |
Muscle Contraction
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. | 0 | 2.04 | 1 | 0 |
Lesion of Sciatic Nerve
[description not available] | 0 | 2.04 | 1 | 0 |
Astrocytoma, Grade IV
[description not available] | 0 | 2.04 | 1 | 0 |
Glioblastoma
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 0 | 2.04 | 1 | 0 |
Anaplastic Astrocytoma
[description not available] | 0 | 2 | 1 | 0 |
Benign Neoplasms, Brain
[description not available] | 0 | 2 | 1 | 0 |
Astrocytoma
Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082) | 0 | 2 | 1 | 0 |
Brain Neoplasms
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 2 | 1 | 0 |