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ddt and Seizures

ddt has been researched along with Seizures in 30 studies

1,1-bis(p-chlorophenyl)-2,2,2-trichloroethane: structure in first source

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"We investigated the interactive effect of DDT (dichlorodiphenyltrichloroethane) on neurodevelopment using a zebrafish (Danio rerio) model for seizure behavior to examine the susceptibility to domoic acid-induced seizures after completion of neurodevelopment."3.75DDT exposure of zebrafish embryos enhances seizure susceptibility: relationship to fetal p,p'-DDE burden and domoic acid exposure of California sea lions. ( Ramsdell, JS; Tiedeken, JA, 2009)
" To study the role of serotonin (5-HT) receptors in myoclonus induced by p,p'-DDT in the rat, we performed time-course and dose-response studies of the effects of p,p'-DDT on behavior and regional 5-HT1 and 5-HT2 binding sites."1.29p,p'-DDT myoclonic/epileptic model: serotonin receptor binding and behavioral studies in the rat. ( Gonzales, W; Pluchino, R; Pranzatelli, MR; Simmens, S; Tailor, PT, 1994)
"Gabapentin dose-dependently attenuated myoclonus in posthypoxic rats for more than 3 h."1.29Antimyoclonic effect of gabapentin in a posthypoxic animal model of myoclonus. ( Kanthasamy, AG; Truong, DD; Vu, TQ; Yun, RJ, 1996)
"Pretreatment with phenytoin, which is thought to bind to the inactivation gates of sodium, had no effect on the effects produced by lindane or kainic acid."1.27The effects of lindane, DDT, and chlordecone on avoidance responding and seizure activity. ( McLamb, RL; Shaw, S; Tilson, HA, 1987)
"Prominal reduced the severity of convulsions in pp'DDT-treated animals."1.26A possible neurochemical basis of the central stimulatory effects of pp'DDT. ( Jaffery, FN; Matin, MA; Siddiqui, RA, 1981)
"The neurochemical changes and convulsions induced by pp'DDT were modified to different degrees by barbiturates."1.26Role of striatal acetylcholine and free ammmonia in the central stimulatory effects of pp'DDT in rats. Protective effects of barbiturates. ( Jaffery, FN; Kar, PP; Matin, MA, 1980)
"Barbiturates control the convulsions produced by the chlorinated hydrocarbon insecticides."1.24The insecticides; their hazard in industry and in the home. ( HALEY, TJ, 1956)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199027 (90.00)18.7374
1990's2 (6.67)18.2507
2000's1 (3.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tiedeken, JA1
Ramsdell, JS1
HECAEN, H1
DEREUX, J1
HALEY, TJ1
LUCKENS, MM1
DAVIS, WH1
GHAZAL, A1
CUNNINGHAM, RE1
HILL, FS1
Swanson, KL1
Woolley, DE4
Matin, MA6
Jaffery, FN2
Siddiqui, RA1
Kar, PP4
Pranzatelli, MR1
Tailor, PT1
Pluchino, R1
Gonzales, W1
Simmens, S1
Kanthasamy, AG1
Vu, TQ1
Yun, RJ1
Truong, DD1
Nigar, F1
Anand, M1
Tilson, HA1
Shaw, S1
McLamb, RL1
Morio, Y1
Imanishi, T1
Nishimura, M1
Yagasaki, O1
St Omer, V1
Peters, DA2
Hrdina, PD2
Singhal, RL2
Ling, GM2
Joy, RM1
Gabliks, J1
Askari, EM1
Yolen, N1
Namba, T1
Greenfield, M1
Grob, D1
Hill, EF1
Dale, WE1
Miles, JW1
Henderson, GL1
Sobotka, TJ1
Black, WD1
Ecobichon, DJ1
Al-Hachim, GM1
Fink, GB1

Reviews

1 review available for ddt and Seizures

ArticleYear
Malathion poisoning. A fatal case with cardiac manifestations.
    Archives of environmental health, 1970, Volume: 21, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Atropine; Cholinesterases; Coma; DDT; Heart Block; Humans; Hyperglyce

1970

Other Studies

29 other studies available for ddt and Seizures

ArticleYear
DDT exposure of zebrafish embryos enhances seizure susceptibility: relationship to fetal p,p'-DDE burden and domoic acid exposure of California sea lions.
    Environmental health perspectives, 2009, Volume: 117, Issue:1

    Topics: Animals; Body Burden; California; DDT; Dichlorodiphenyl Dichloroethylene; Environmental Exposure; Fe

2009
[Epileptic-like state following DDT poisoning].
    Revue neurologique, 1955, Volume: 92, Issue:2

    Topics: DDT; Diagnosis, Differential; Epilepsy; Humans; Poisoning; Seizures

1955
The insecticides; their hazard in industry and in the home.
    California medicine, 1956, Volume: 84, Issue:4

    Topics: Aldrin; Atropine; Autonomic Nervous System; Chlordan; Cholinesterases; DDT; Hexachlorocyclohexane; I

1956
BATS: SENSITIVITY TO DDT.
    Science (New York, N.Y.), 1964, Nov-13, Volume: 146, Issue:3646

    Topics: Animals; Body Weight; Chiroptera; DDT; Pharmacology; Research; Seizures; Toxicology; Tremor

1964
CHLOROPHENOTHANE (DDT) AND GLUTAMINE IN PENTYLENETETRAZOLE (CARDIAZOLE) CONVULSIONS IN THE RAT.
    Toxicology and applied pharmacology, 1964, Volume: 6

    Topics: DDT; Glutamine; Metabolism; Pentylenetetrazole; Pharmacology; Rats; Research; Seizures

1964
Convulsions and deafness following ingestion of DDT.
    Pediatrics, 1952, Volume: 9, Issue:6

    Topics: DDT; Deafness; Eating; Hearing Disorders; Hearing Loss; Hearing Tests; Humans; Seizures

1952
Comparison of the neurotoxic effects of chlordecone and dieldrin in the rat.
    Neurotoxicology, 1982, Volume: 3, Issue:2

    Topics: Animals; Behavior, Animal; Body Temperature; Chlordecone; DDT; Dieldrin; Dose-Response Relationship,

1982
A possible neurochemical basis of the central stimulatory effects of pp'DDT.
    Journal of neurochemistry, 1981, Volume: 36, Issue:3

    Topics: Acetylcholine; Aminooxyacetic Acid; Ammonia; Animals; Central Nervous System; Corpus Striatum; DDT;

1981
Role of striatal acetylcholine and free ammmonia in the central stimulatory effects of pp'DDT in rats. Protective effects of barbiturates.
    Archives of toxicology, 1980, Volume: 45, Issue:1

    Topics: Acetylcholine; Ammonia; Animals; Barbiturates; Central Nervous System; Corpus Striatum; DDT; Male; R

1980
p,p'-DDT myoclonic/epileptic model: serotonin receptor binding and behavioral studies in the rat.
    Neurotoxicology, 1994,Summer, Volume: 15, Issue:2

    Topics: 5,7-Dihydroxytryptamine; Animals; Behavior, Animal; DDT; Disease Models, Animal; Epilepsies, Myoclon

1994
Antimyoclonic effect of gabapentin in a posthypoxic animal model of myoclonus.
    European journal of pharmacology, 1996, Feb-22, Volume: 297, Issue:3

    Topics: Acetates; Acoustic Stimulation; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; DDT;

1996
A study of the effects of certain barbiturates on the level of striatal acetylcholine and convulsions in 1,1,1-trichloro-2,2-bis(4'-chlorophenyl) ethane (pp' DDT) treated rats.
    Pharmacological research communications, 1979, Volume: 11, Issue:4

    Topics: Acetylcholine; Animals; Barbiturates; Corpus Striatum; DDT; Drug Interactions; Male; Rats; Seizures

1979
Modification of pp' DDT induced convulsions by changes in the level of cerebral gamma-aminobutyric acid in mice.
    Journal of neurochemistry, 1976, Volume: 27, Issue:4

    Topics: Aminobutyrates; Aminooxyacetic Acid; Ammonia; Animals; Brain; DDT; gamma-Aminobutyric Acid; Hydroxyl

1976
The effects of lindane, DDT, and chlordecone on avoidance responding and seizure activity.
    Toxicology and applied pharmacology, 1987, Mar-30, Volume: 88, Issue:1

    Topics: Animals; Avoidance Learning; Chlordecone; Chlordiazepoxide; DDT; Dose-Response Relationship, Drug; H

1987
Characteristics of neuronal effects of DDT and dieldrin in mice.
    Nihon juigaku zasshi. The Japanese journal of veterinary science, 1987, Volume: 49, Issue:6

    Topics: Animals; DDT; Dieldrin; Male; Mice; Nervous System; Seizures; Tremor

1987
Investigations into mechanisms responsible for seizures induced by chlorinated hydrocarbon insecticides: the role of brain ammonia and glutamine in convulsions in the rat and cockerel.
    Journal of neurochemistry, 1971, Volume: 18, Issue:3

    Topics: Ammonia; Animals; Brain; Bridged-Ring Compounds; Chickens; DDT; Dieldrin; Female; Glutamine; Hexachl

1971
Possible role of cerebral amino acids in acute neurotoxic effects of DDT in mice.
    European journal of pharmacology, 1974, Volume: 25, Issue:1

    Topics: Amino Acids; Animals; Behavior, Animal; Brain; Brain Chemistry; DDT; gamma-Aminobutyric Acid; Glycin

1974
Effect of barbiturates and isoniazid on cerebral hemisphere gamma-aminobutyric acid content in pp' DDT treated mice.
    Pharmacological research communications, 1974, Volume: 6, Issue:4

    Topics: Aminobutyrates; Animals; Anticonvulsants; Barbiturates; Behavior, Animal; Brain Chemistry; DDT; Drug

1974
The role of brain serotonin in DDT-induced hyperpyrexia.
    Journal of neurochemistry, 1972, Volume: 19, Issue:4

    Topics: Animals; Brain; Brain Stem; DDT; Fenclonine; Fever; Fluorine; Hydroxyindoleacetic Acid; Male; Pargyl

1972
Electrical correlates of preconvulsive and convulsive doses of chlorinated hydrocarbon insecticides in the CNS.
    Neuropharmacology, 1973, Volume: 12, Issue:1

    Topics: Animals; Cats; Caudate Nucleus; Central Nervous System; Cerebellum; Cerebral Cortex; DDT; Dieldrin;

1973
DDT and immunological responses. I. Serum antibodies and anaphylactic shock in guinea pigs.
    Archives of environmental health, 1973, Volume: 26, Issue:6

    Topics: Anaphylaxis; Animals; Antibody Formation; Blood Protein Electrophoresis; Body Weight; DDT; Diphtheri

1973
DDT intoxication in birds: subchronic effects and brain residues.
    Toxicology and applied pharmacology, 1971, Volume: 20, Issue:4

    Topics: Animals; Birds; Body Weight; Brain Chemistry; Chromatography, Gas; DDT; Dichlorodiphenyldichloroetha

1971
Role of brain acetylcholine and dopamine in acute neurotoxic effects of DDT.
    European journal of pharmacology, 1971, Volume: 15, Issue:3

    Topics: Acetylcholine; Animals; Basal Ganglia; Central Nervous System; DDT; Dopamine; Female; Male; Rats; Se

1971
Effects of acute and chronic exposure to DDT and of DDT-drug interactions on experimental seizure responses.
    IMS, Industrial medicine and surgery, 1970, Volume: 39, Issue:8

    Topics: Animals; Central Nervous System; DDT; Dieldrin; Electroshock; Female; Injections, Subcutaneous; Intu

1970
Effects of DDT and of drug-DDT interactions on electroshock seizures in the rat.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:2

    Topics: Animals; Central Nervous System; DDT; Drug Antagonism; Drug Synergism; Electroshock; Female; Pentoba

1970
Mechanisms of neurotoxic action of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) in immature and adult rats.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:1

    Topics: Age Factors; Animals; Body Temperature; Brain; Cerebellum; DDT; Electrocardiography; Electrodes; Ele

1970
Behavioral effects of low doses of DDT.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 137, Issue:3

    Topics: Animals; Avoidance Learning; Central Nervous System; DDT; Electroshock; Exploratory Behavior; Habitu

1971
A pharmacodynamic study of DDT in rabbits following acute intravenous administration.
    Canadian journal of physiology and pharmacology, 1971, Volume: 49, Issue:1

    Topics: Adipose Tissue; Animals; Brain; Brain Chemistry; DDT; Female; Kidney; Liver; Lung; Muscles; Myocardi

1971
Effect of DDT or parathion on the minimal electroshock seizure threshold of offspring from DDT or parathion-treated mothers.
    Psychopharmacologia, 1968, Volume: 13, Issue:5

    Topics: Animals; Animals, Newborn; Brain; DDT; Electroshock; Female; Maternal-Fetal Exchange; Mice; Parathio

1968