guanidine has been researched along with Seizures in 3 studies
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
guanidine : An aminocarboxamidine, the parent compound of the guanidines.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperargininemia is caused by deficiency of arginase 1, which catalyzes the hydrolysis of L-arginine to urea as the final enzyme in the urea cycle." | 8.91 | Hyperargininemia due to arginase I deficiency: the original patients and their natural history, and a review of the literature. ( Ensenauer, R; Häussinger, D; Mayatepek, E; Schlune, A; Vom Dahl, S, 2015) |
| "Hyperargininemia is caused by deficiency of arginase 1, which catalyzes the hydrolysis of L-arginine to urea as the final enzyme in the urea cycle." | 4.91 | Hyperargininemia due to arginase I deficiency: the original patients and their natural history, and a review of the literature. ( Ensenauer, R; Häussinger, D; Mayatepek, E; Schlune, A; Vom Dahl, S, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schlune, A | 1 |
| Vom Dahl, S | 1 |
| Häussinger, D | 1 |
| Ensenauer, R | 1 |
| Mayatepek, E | 1 |
| Maillard, MC | 1 |
| Perlman, ME | 2 |
| Amitay, O | 1 |
| Baxter, D | 1 |
| Berlove, D | 2 |
| Connaughton, S | 1 |
| Fischer, JB | 2 |
| Guo, JQ | 1 |
| Hu, LY | 1 |
| McBurney, RN | 1 |
| Nagy, PI | 1 |
| Subbarao, K | 1 |
| Yost, EA | 1 |
| Zhang, L | 2 |
| Durant, GJ | 2 |
| Reddy, NL | 1 |
| Fan, W | 1 |
| Magar, SS | 1 |
| Yost, E | 1 |
| Burke-Howie, K | 1 |
| Wolcott, T | 1 |
1 review available for guanidine and Seizures
| Article | Year |
|---|---|
Hyperargininemia due to arginase I deficiency: the original patients and their natural history, and a review of the literature.
Topics: Arginase; Arginine; Child, Preschool; Female; Guanidine; Humans; Hyperammonemia; Hyperargininemia; I | 2015 |
2 other studies available for guanidine and Seizures
| Article | Year |
|---|---|
Design, synthesis, and pharmacological evaluation of conformationally constrained analogues of N,N'-diaryl- and N-aryl-N-aralkylguanidines as potent inhibitors of neuronal Na+ channels.
Topics: Animals; Anticonvulsants; Biological Transport; Brain; Calcium; Calcium Channel Blockers; Calcium Ch | 1998 |
Synthesis and pharmacological evaluation of N,N'-diarylguanidines as potent sodium channel blockers and anticonvulsant agents.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Cell Line; CHO Cells; Cricetinae; Drug Design; Guani | 1998 |