Compounds > homocysteinesulfinic acid
Page last updated: 2024-09-26

homocysteinesulfinic acid

Description

homocysteinesulfinic acid: RN given refers to cpd without isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID161712
CHEBI ID137439
SCHEMBL ID22635954
MeSH IDM0056933

Synonyms (16)

Synonym
l-homocysteinesulfinic acid, >=98% (tlc)
d-homocysteinesulfinic acid, >=98% (tlc)
homocysteine sulfinic acid
CHEBI:137439
homocysteinesulfinic acid
31523-80-5
butanoic acid, 2-amino-4-sulfino-
2-amino-4-sulfinobutanoic acid
FT-0639107
FT-0634441
2-amino-4-sulfino-butanoate
2-amino-4-sulfino-butyric acid
2-amino-4-sulfinobutyric acid
2-amino-4-sulfino-butanoic acid
DTXSID60953508
SCHEMBL22635954

Drug Classes (1)

ClassDescription
alpha-amino acidAn amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (1)

homocysteinesulfinic acid is involved in 1 pathway(s), involving a total of 0 unique proteins and 11 unique compounds

PathwayProteinsCompounds
CAMKK2 pathway011

Research

Studies (23)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (26.09)18.7374
1990's8 (34.78)18.2507
2000's6 (26.09)29.6817
2010's2 (8.70)24.3611
2020's1 (4.35)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (4.35%)5.53%
Reviews1 (4.35%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other21 (91.30%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
cysteic acid[no description available]medium70alanine derivative;
amino sulfonic acid;
carboxyalkanesulfonic acid;
cysteine derivative;
non-proteinogenic alpha-amino acid		animal metabolite
homocysteine[no description available]medium231amino acid zwitterion;
homocysteine;
serine family amino acid		fundamental metabolite;
mouse metabolite
carnitine[no description available]medium10amino-acid betainehuman metabolite;
mouse metabolite
folic acid[no description available]medium10folic acids;
N-acyl-amino acid		human metabolite;
mouse metabolite;
nutrient
methotrexate[no description available]medium21dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent
dextromethorphan[no description available]medium106-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthreneantitussive;
environmental contaminant;
neurotoxin;
NMDA receptor antagonist;
oneirogen;
prodrug;
xenobiotic
glutamic acid[no description available]medium40glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical
homocysteic acid[no description available]medium110homocysteic acidNMDA receptor agonist
n-methylaspartate[no description available]medium50amino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound		neurotransmitter agent
2-amino-5-phosphonovalerate[no description available]medium10non-proteinogenic alpha-amino acidNMDA receptor antagonist
valine[no description available]medium10L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
thapsigargin[no description available]medium10butyrate ester;
organic heterotricyclic compound;
sesquiterpene lactone		calcium channel blocker;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor
rhod-2[no description available]medium10
s-adenosylmethionine[no description available]medium11organic cation;
sulfonium compound		coenzyme;
cofactor;
human metabolite;
micronutrient;
Mycoplasma genitalium metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
cytarabine[no description available]medium11beta-D-arabinoside;
monosaccharide derivative;
pyrimidine nucleoside		antimetabolite;
antineoplastic agent;
antiviral agent;
immunosuppressive agent
piperidines[no description available]medium10
cp 99994[no description available]medium10
substance p[no description available]medium10peptideneurokinin-1 receptor agonist;
neurotransmitter;
vasodilator agent
deuterium[no description available]medium10dihydrogen
aspartic acid[no description available]medium60aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
cysteine[no description available]medium80cysteiniumfundamental metabolite
cysteine sulfinic acid[no description available]medium80
1-amino-1,3-dicarboxycyclopentane[no description available]medium10
cycloleucine[no description available]medium10non-proteinogenic alpha-amino acidEC 2.5.1.6 (methionine adenosyltransferase) inhibitor
s-sulphocysteine[no description available]medium30organic thiosulfate;
S-substituted L-cysteine		human metabolite;
plant metabolite
6-cyano-7-nitroquinoxaline-2,3-dione[no description available]medium10quinoxaline derivative
quisqualic acid[no description available]medium50non-proteinogenic alpha-amino acid
serine o-sulfate[no description available]medium10L-serine derivative;
non-proteinogenic L-alpha-amino acid;
O-sulfoamino acid
serine[no description available]medium10L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
methionine[no description available]medium10aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
fg 9041[no description available]medium10quinoxaline derivative
quinoxalines[no description available]medium10mancude organic heterobicyclic parent;
naphthyridine;
ortho-fused heteroarene
2-amino-4-phosphonobutyric acid[no description available]medium10
kainic acid[no description available]medium30dicarboxylic acid;
L-proline derivative;
non-proteinogenic L-alpha-amino acid;
pyrrolidinecarboxylic acid		antinematodal drug;
excitatory amino acid agonist
ibotenic acid[no description available]medium10non-proteinogenic alpha-amino acidneurotoxin
oxadiazoles[no description available]medium30
quinolinic acid[no description available]medium10pyridinedicarboxylic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite;
NMDA receptor agonist
veratrine[no description available]medium10alkaloid
DL-Canavanine[no description available]low00alpha-amino acid
n(g),n(g')-dimethyl-l-arginine[no description available]low00alpha-amino acid
cysteine[no description available]low00alpha-amino acid;
amino acid zwitterion;
polar amino acid;
sulfur-containing amino acid		fundamental metabolite
alanine[no description available]low00alpha-amino acid;
amino acid zwitterion		fundamental metabolite
glycine[no description available]low00alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
endolysin[no description available]low00alpha-amino acid;
diamino acid;
polar amino acid		Daphnia magna metabolite
racemethionine[no description available]low00alpha-amino acid;
amino acid zwitterion;
sulfur-containing amino acid		algal metabolite;
Daphnia magna metabolite;
Escherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
phenylalanine[no description available]low00alpha-amino acid;
aromatic amino acid		Daphnia magna metabolite
tryptophan[no description available]low00alpha-amino acid;
amino acid zwitterion;
aminoalkylindole;
aromatic amino acid;
polar amino acid		Daphnia magna metabolite
(alpha-carboxycyclopropyl)glycine[no description available]low00alpha-amino acid
1-aminocyclohexanecarboxylic acid[no description available]low00alpha-amino acid
2-amino-3-(5-tert-butyl-3-oxo-4-isoxazolyl)propanoic acid[no description available]low00alpha-amino acid
alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate[no description available]low00alpha-amino acid
eflornithine[no description available]low00alpha-amino acid;
fluoroamino acid		trypanocidal drug
mimosine[no description available]low00alpha-amino acid
4-carboxyphenylglycine[no description available]low00alpha-amino acid
acediasulfone[no description available]low00alpha-amino acid
methiin[no description available]low00alpha-amino acid
2-amino-5-hydroxyvaleric acid[no description available]low00alpha-amino acid
1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid[no description available]low00alpha-amino acid;
aromatic amino acid;
beta-carboline alkaloid		human urinary metabolite;
human xenobiotic metabolite;
plant metabolite;
rat metabolite
3,5-dihydroxyphenylglycine[no description available]low00alpha-amino acid
alliin[no description available]low00alpha-amino acid
laminine[no description available]low00alpha-amino acid
spinacine[no description available]low00alpha-amino acid
edba[no description available]low00alpha-amino acid
tissue plasminogen activator[no description available]low00alpha-amino acid
ubp296[no description available]low00alpha-amino acid
cycloalliin[no description available]low00alpha-amino acid
furosine[no description available]low00alpha-amino acid
4-hydroxy-4-(indol-3-ylmethyl)glutamic acid[no description available]low00alpha-amino acid
ConditionIndicatedRelationship StrengthStudiesTrials
Absence Seizure0low10
Absence Seizures0low10
Age-Related Memory Disorders0low10
Atonic Absence Seizure0low10
Atonic Absence Seizures0low10
Atonic Seizure0low10
Atonic Seizures0low10
Cardiovascular Stroke0low10
Central Nervous System Neoplasm0medium11
Central Nervous System Neoplasms0medium11
Central Nervous System Neoplasms, Primary0medium11
Central Nervous System Tumor0medium11
Central Nervous System Tumors0medium11
Clonic Seizure0low10
Clonic Seizures0low10
CNS Neoplasm0medium11
CNS Neoplasms0medium11
Cognition Disorders0low10
Complex Partial Seizure0low10
Complex Partial Seizures0low10
Convulsion0low10
Convulsion, Non-Epileptic0low10
Convulsions0low10
Convulsive Seizure0low10
Convulsive Seizures0low10
Deficiency, Pyridoxine0low10
Deficiency, Vitamin B 60low10
Deficiency, Vitamin B60low10
Disease Models, Animal0low10
Encephalopathy, Toxic0medium11
Epileptic Seizure0low10
Epileptic Seizures0low10
Generalized Absence Seizure0low10
Generalized Absence Seizures0low10
Generalized Tonic-Clonic Seizures0low10
Germinoblastoma0medium11
Heart Attack0low10
Hyperhomocysteinemia0low10
Jacksonian Seizure0low10
Lymphoma0medium11
Lymphoma, Malignant0medium11
Memory Deficits0low10
Memory Disorder, Semantic0low10
Memory Disorder, Spatial0low10
Memory Disorders0low10
Memory Disorders, Age-Related0low10
Memory Loss0low10
Myocardial Infarct0low10
Myocardial Infarction0low10
Myoclonic Seizure0low10
Myoclonic Seizures0low10
Neoplasms, Central Nervous System0medium11
Nervous System Poisoning0medium11
Neurotoxic Disorders0medium11
Neurotoxicity Syndromes0medium11
Neurotoxin Diseases0medium11
Neurotoxin Disorders0medium11
Non-Epileptic Seizure0low10
Non-Epileptic Seizures0low10
Nonepileptic Seizure0low10
Nonepileptic Seizures0low10
Overinclusion0low10
Partial Seizure0low10
Partial Seizures0low10
Petit Mal Convulsion0low10
Poisoning, Nervous System0medium11
Primary Central Nervous System Neoplasm0medium11
Primary Central Nervous System Neoplasms0medium11
Pyridoxine Deficiency0low10
Retention Disorders, Cognitive0low10
Reticulolymphosarcoma0medium11
Sarcoma, Germinoblastic0medium11
Seizure0low10
Seizures0low10
Seizures, Auditory0low10
Seizures, Clonic0low10
Seizures, Convulsive0low10
Seizures, Epileptic0low10
Seizures, Focal0low10
Seizures, Generalized0low10
Seizures, Gustatory0low10
Seizures, Motor0low10
Seizures, Olfactory0low10
Seizures, Sensory0low10
Seizures, Somatosensory0low10
Seizures, Tonic0low10
Seizures, Tonic-Clonic0low10
Seizures, Vertiginous0low10
Seizures, Vestibular0low10
Seizures, Visual0low10
Semantic Memory Disorder0low10
Single Seizure0low10
Spatial Memory Disorder0low10
Tonic Clonic Seizure0low10
Tonic Seizure0low10
Tonic Seizures0low10
Tonic-Clonic Seizure0low10
Tonic-Clonic Seizures0low10
Toxic Encephalitis0medium11
Tumors, Central Nervous System0medium11
Vitamin B 6 Deficiency0low10
Vitamin B6 Deficiency0low10
Vitamin Deficiency, B60low10

Research Highlights

Dosage (1)

ArticleYear
Implications for hyperhomocysteinemia: not homocysteine but its oxidized forms strongly inhibit neuronal network activity.
Journal of the neurological sciences, Mar-15, Volume: 218, Issue: 1-2		2004
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]