quinacrine has been researched along with Seizures in 13 studies
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The decrease in the seizure threshold for pentylenetetrazole during diazepam withdrawal was significantly suppressed by intracerebroventricular (i." | 1.38 | Involvement of the arachidonic acid cascade in the hypersusceptibility to pentylenetetrazole-induced seizure during diazepam withdrawal. ( Mori, T; Shibasaki, M; Shimizu, N; Suzuki, T, 2012) |
| "A patients with seizures, Von Willebrand disease, and symptoms of Turner syndrome was a chromosomal mosaic." | 1.26 | Structure and Barr body formation of an Xp + chromosome with two inactivation centers. ( Daly, RF; Patau, K; Sarto, GE; Therman, E, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmad, M | 1 |
| Abu-Taweel, GM | 1 |
| Aboshaiqah, AE | 1 |
| Ajarem, JS | 1 |
| WELCH, WJ | 2 |
| BAUMAN, E | 1 |
| KNOWLTON, P | 1 |
| Mori, T | 1 |
| Shimizu, N | 1 |
| Shibasaki, M | 1 |
| Suzuki, T | 1 |
| UZUNOV, G | 1 |
| BOZHINOV, S | 1 |
| GEORGIEV, I | 1 |
| SOREL, L | 1 |
| ROSENBERG, FJ | 1 |
| BOTTIROLI, JA | 1 |
| FULTON, WH | 1 |
| DYKEN, PR | 1 |
| MITCHELL, CL | 1 |
| SIMON, H | 1 |
| Borda, I | 1 |
| Krant, M | 1 |
| Daly, RF | 1 |
| Patau, K | 1 |
| Therman, E | 1 |
| Sarto, GE | 1 |
| Tumada, LR | 1 |
| Margono, SS | 1 |
13 other studies available for quinacrine and Seizures
| Article | Year |
|---|---|
The effects of quinacrine, proglumide, and pentoxifylline on seizure activity, cognitive deficit, and oxidative stress in rat lithium-pilocarpine model of status epilepticus.
Topics: Animals; Cognition Disorders; Lithium Compounds; Male; Oxidative Stress; Pentoxifylline; Pilocarpine | 2014 |
Syphilis of the central nervous system; effect of quinacrine hydrochloride on the incidence of convulsions.
Topics: Central Nervous System; Incidence; Neurosyphilis; Quinacrine; Seizures; Syphilis | 1948 |
The incidence of convulsions in general paretics receiving quinacrine.
Topics: Incidence; Malaria; Neurosyphilis; Paralysis; Quinacrine; Seizures; Therapeutics | 1946 |
Involvement of the arachidonic acid cascade in the hypersusceptibility to pentylenetetrazole-induced seizure during diazepam withdrawal.
Topics: Animals; Arachidonic Acid; Convulsants; Cyclooxygenase Inhibitors; Diazepam; Diclofenac; Enzyme Inhi | 2012 |
[Experimental investigations on pathogenesis of atabrine epileptiform seizure].
Topics: Epilepsy; Glomerulonephritis; Quinacrine; Seizures | 1954 |
[Experimental and clinical anti-epileptic actions of mepacrine (atebrine), of celontin and of elyptene].
Topics: Anticonvulsants; Epilepsy; Quinacrine; Seizures; Succinimides | 1959 |
ANTIMALARIALS AND OTHER ANTICONVULSANT DRUGS: PREDICTIVE VALIDITY OF LABORATORY TESTS.
Topics: Animals; Anticonvulsants; Antimalarials; Chloroquine; Electric Stimulation; Hydroxychloroquine; Mice | 1964 |
NEUROLOGICAL SYNDROMES OF SYSTEMIC LUPUS ERYTHEMATOSUS.
Topics: Adolescent; Anticonvulsants; Autoimmune Diseases; Blood Proteins; Cerebral Cortex; Cerebrospinal Flu | 1964 |
THE ABSENCE OF ANTICONVULSANT PROPERTIES OF QUINACRINE AND CHLOROQUINE IN MICE.
Topics: Anticonvulsants; Chloroquine; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Quinacrine; Res | 1964 |
Epileptic fit after oral administration of atabrine (in Hebrew; English summary).
Topics: Administration, Oral; Epilepsy; Language; Malaria; Quinacrine; Seizures | 1950 |
Convulsions following intrapleural administration of quinacrine hydrochloride.
Topics: Adult; Breast Neoplasms; Epilepsy; Female; Genital Neoplasms, Female; Humans; Middle Aged; Neoplasm | 1967 |
Structure and Barr body formation of an Xp + chromosome with two inactivation centers.
Topics: Adolescent; Female; Humans; Mosaicism; Quinacrine; Seizures; Sex Chromatin; Sex Chromosome Aberratio | 1977 |
Cysticercosis in the area of the Wissel Lakes, West Irian.
Topics: Adolescent; Adult; Ascariasis; Cysticercosis; Diethylcarbamazine; Female; Headache; Hookworm Infecti | 1973 |