amiodarone has been researched along with Seizures in 10 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a case where these episodes were caused by recurrent ventricular tachycardia/ventricular fibrillation secondary to idiopathic long QT syndrome which was effectively treated with amiodarone." | 7.68 | Effective management of long Q-T syndrome with amiodarone. ( Ainon, S; Gururaj, AK, 1990) |
| " Acute amiodarone at the dose of 75 mg/kg significantly potentiated the anticonvulsive effect of carbamazepine, but not that of valproate, phenytoin or phenobarbital in the maximal electroshock-induced seizures in mice." | 3.88 | Amiodarone, a multi-channel blocker, enhances anticonvulsive effect of carbamazepine in the mouse maximal electroshock model. ( Banach, M; Borowicz-Reutt, KK; Popławska, M, 2018) |
| "Accidental intravascular administration of bupivacaine during performance of a brachial block precipitated convulsions followed by asystole." | 3.75 | Recurrence of cardiotoxicity after lipid rescue from bupivacaine-induced cardiac arrest. ( Coetzee, AR; Levin, AI; Marwick, PC, 2009) |
| "We report a case of lidocaine toxicity with seizures that appears to represent a drug interaction with amiodarone." | 3.68 | Amiodarone interaction with lidocaine. ( Imhoff, TE; Siegmund, JB; Wilson, JH, 1993) |
| " We report a case where these episodes were caused by recurrent ventricular tachycardia/ventricular fibrillation secondary to idiopathic long QT syndrome which was effectively treated with amiodarone." | 3.68 | Effective management of long Q-T syndrome with amiodarone. ( Ainon, S; Gururaj, AK, 1990) |
| "Amiodarone hydrochloride is a potent anti-arrhythmic agent, known as a multiple ion-channel blocker in the heart." | 1.35 | Anticonvulsant and hypnotic effects of amiodarone. ( Bakirci, A; Ozbakis-Dengiz, G, 2009) |
| "The amiodarone drip was discontinued." | 1.35 | Management of isolated yew berry toxicity with sodium bicarbonate: a case report in treatment efficacy. ( Donovan, JW; Kane, B; Kane, K; Pierog, J, 2009) |
| "The patient presented with episodes of seizure-like activity, which were subsequently shown to be caused by ventricular fibrillation." | 1.34 | Varicella zoster induced cardiac dysfunction: a case report. ( Dennison, P; Zaremba, E, 2007) |
| " Second, based on preliminary investigations, an approximate intraperitoneal LD50 dose of cocaine (110 mg/kg) was identified and used as the cocaine dose in this study." | 1.33 | The effect of amiodarone pretreatment on survival of mice with cocaine toxicity. ( Cleveland, N; Dart, RC; DeWitt, CR; Heard, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banach, M | 1 |
| Popławska, M | 1 |
| Borowicz-Reutt, KK | 1 |
| Kalimullah, EA | 1 |
| Bryant, SM | 1 |
| Marwick, PC | 1 |
| Levin, AI | 1 |
| Coetzee, AR | 1 |
| Ozbakis-Dengiz, G | 1 |
| Bakirci, A | 1 |
| Pierog, J | 1 |
| Kane, B | 1 |
| Kane, K | 1 |
| Donovan, JW | 1 |
| Dennison, P | 1 |
| Zaremba, E | 1 |
| DeWitt, CR | 1 |
| Cleveland, N | 1 |
| Dart, RC | 1 |
| Heard, K | 1 |
| Gore, JM | 1 |
| Haffajee, CI | 1 |
| Alpert, JS | 1 |
| Siegmund, JB | 1 |
| Wilson, JH | 1 |
| Imhoff, TE | 1 |
| Gururaj, AK | 1 |
| Ainon, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Investigation Into the Effects of Intravenous Lipid Emulsion (ILE) on the Pharmacokinetic and Pharmacodynamic Properties of Metoprolol.[NCT02924454] | Phase 4 | 10 participants (Actual) | Interventional | 2016-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 other studies available for amiodarone and Seizures
| Article | Year |
|---|---|
Amiodarone, a multi-channel blocker, enhances anticonvulsive effect of carbamazepine in the mouse maximal electroshock model.
Topics: Amiodarone; Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Re | 2018 |
Case files of the medical toxicology fellowship at the toxikon consortium in Chicago: cocaine-associated wide-complex dysrhythmias and cardiac arrest - treatment nuances and controversies.
Topics: Amiodarone; Anti-Arrhythmia Agents; Anticonvulsants; Antidotes; Arrhythmias, Cardiac; Charcoal; Coca | 2008 |
Recurrence of cardiotoxicity after lipid rescue from bupivacaine-induced cardiac arrest.
Topics: Adult; Amiodarone; Anesthetics, Local; Anti-Arrhythmia Agents; Brachial Plexus; Bupivacaine; Cardiop | 2009 |
Anticonvulsant and hypnotic effects of amiodarone.
Topics: Amiodarone; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Mal | 2009 |
Management of isolated yew berry toxicity with sodium bicarbonate: a case report in treatment efficacy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Antidotes; Drug Therapy, Combination; Electrocardiography; Human | 2009 |
Varicella zoster induced cardiac dysfunction: a case report.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Chickenpox; Electrocardiography; Humans; Male; Seizures; | 2007 |
The effect of amiodarone pretreatment on survival of mice with cocaine toxicity.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cocaine; Disease Models, Animal; Drug Antagonism; Injec | 2005 |
Interaction of amiodarone and diphenylhydantoin.
Topics: Aged; Amiodarone; Ataxia; Benzofurans; Drug Interactions; Humans; Male; Myocardial Infarction; Pheny | 1984 |
Amiodarone interaction with lidocaine.
Topics: Aged; Amiodarone; Drug Interactions; Humans; Infusions, Intravenous; Lidocaine; Male; Seizures | 1993 |
Effective management of long Q-T syndrome with amiodarone.
Topics: Amiodarone; Child; Electrocardiography; Humans; Long QT Syndrome; Male; Seizures | 1990 |