pyridoxal has been researched along with Seizures in 6 studies
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to study whether a theophylline-related seizure is caused by a decrease in serum vitamin B6, serum pyridoxal (PAL) levels were measured in children with bronchial asthma treated with theophylline." | 7.70 | [Depression of serum pyridoxal levels in theophylline-related seizures]. ( Furukawa, K; Hattori, H; Hayashi, K; Inada, H; Isshiki, G; Kobayashi, N; Matsuoka, O; Seto, T; Tada, H, 2000) |
| " In the present study, we found that pyridoxal-5'-phosphate phosphatase/chronophin (PLPP/CIN) transiently dephosphorylated DARPP-32 serine (S) 97 site in the early time window, and casein kinase 2 (CK2) subsequently phosphorylated this site in the later time points after kainic acid (KA) injection, which increased the latency of seizure onset in response to KA, but exacerbated the intensity (severity), duration and progression of seizures." | 4.12 | PLPP/CIN-mediated DARPP-32 serine 97 dephosphorylation delays the seizure onset in response to kainic acid in the mouse hippocampus. ( Kang, TC; Kim, JE; Kim, MJ; Kim, TH; Lee, DS; Park, H, 2022) |
| "In order to study whether a theophylline-related seizure is caused by a decrease in serum vitamin B6, serum pyridoxal (PAL) levels were measured in children with bronchial asthma treated with theophylline." | 3.70 | [Depression of serum pyridoxal levels in theophylline-related seizures]. ( Furukawa, K; Hattori, H; Hayashi, K; Inada, H; Isshiki, G; Kobayashi, N; Matsuoka, O; Seto, T; Tada, H, 2000) |
| " Seizures were induced by pyridoxal phosphate-gamma-glutamyl hydrazone (PLPGH), a drug previously reported to reduce the levels of pyridoxal 5'-phosphate and as a consequence to inhibit the activity of glutamate decarboxylase in brain of adult mice." | 3.65 | Seizure susceptibility in the developing mouse and its relationship to glutamate decarboxylase and pyridoxal phosphate in brain. ( Pasantes-Morales, H; Pérez de la Mora, M; Taborda, E; Tapia, R, 1975) |
| "The initial presentation of acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is indistinguishable from that of complex febrile seizures (FS), which poses a great diagnostic challenge for clinicians." | 1.56 | Vitamin B6 in acute encephalopathy with biphasic seizures and late reduced diffusion. ( Akiyama, T; Hanaoka, Y; Hyodo, Y; Ito, T; Kimura, N; Kobayashi, K; Miyahara, H; Mogami, Y; Toda, S; Tokorodani, C, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, JE | 1 |
| Lee, DS | 1 |
| Kim, TH | 1 |
| Park, H | 1 |
| Kim, MJ | 1 |
| Kang, TC | 1 |
| Akiyama, T | 1 |
| Toda, S | 1 |
| Kimura, N | 1 |
| Mogami, Y | 1 |
| Hanaoka, Y | 1 |
| Tokorodani, C | 1 |
| Ito, T | 1 |
| Miyahara, H | 1 |
| Hyodo, Y | 1 |
| Kobayashi, K | 1 |
| Mizuno, N | 1 |
| Kawakami, K | 1 |
| Morita, E | 1 |
| Seto, T | 1 |
| Inada, H | 1 |
| Kobayashi, N | 1 |
| Tada, H | 1 |
| Furukawa, K | 1 |
| Hayashi, K | 1 |
| Hattori, H | 1 |
| Matsuoka, O | 1 |
| Isshiki, G | 1 |
| Tapia, R | 1 |
| Pasantes-Morales, H | 1 |
| Taborda, E | 1 |
| Pérez de la Mora, M | 1 |
| Murakami, Y | 1 |
| Matsuda, M | 1 |
6 other studies available for pyridoxal and Seizures
| Article | Year |
|---|---|
PLPP/CIN-mediated DARPP-32 serine 97 dephosphorylation delays the seizure onset in response to kainic acid in the mouse hippocampus.
Topics: Animals; Casein Kinase II; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Hippocampus; Kai | 2022 |
Vitamin B6 in acute encephalopathy with biphasic seizures and late reduced diffusion.
Topics: Brain Diseases; Child, Preschool; Female; Humans; Infant; Male; Pyridoxal; Pyridoxal Phosphate; Seiz | 2020 |
Competitive inhibition between 4'-substituted pyridoxine analogues and pyridoxal for pyridoxal kinase from mouse brain.
Topics: Animals; Binding, Competitive; Brain; Kinetics; Mice; Phosphotransferases; Pyridoxal; Pyridoxal Kina | 1980 |
[Depression of serum pyridoxal levels in theophylline-related seizures].
Topics: Adolescent; Adult; Asthma; Biomarkers; Child; Child, Preschool; Humans; Male; Pyridoxal; Seizures; T | 2000 |
Seizure susceptibility in the developing mouse and its relationship to glutamate decarboxylase and pyridoxal phosphate in brain.
Topics: Animals; Brain; Carboxy-Lyases; Convulsants; Glutamate Decarboxylase; Mice; Phosphotransferases; Pyr | 1975 |
The effect of castrix (2-chloro-4- dimethylamino-6-methylpyrimidine) on the distribution of B6 vitamers in mouse brain.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Isoniazid; Male; Mice; Penicillamine; Pyridoxa | 1976 |