berberine has been researched along with Seizures in 4 studies
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Berberine (BBR), an isoquinoline alkaloid, has shown promising effect in the kindling model of epileptogenesis, but due to the poor oral bioavailability its clinical application is limited." | 5.91 | Neuroprotective effect of Berberine Nanoparticles Against Seizures in Pentylenetetrazole Induced Kindling Model of Epileptogenesis: Role of Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Mechanisms. ( Bhatia, A; Bhattacharya, S; Chakrabarti, A; Gautam, V; Kumari, P; Rawat, K; Saha, L; Sandhu, A; Singh, N; Sinha, VR, 2023) |
| "Epileptic seizures are characterized by synchronized discharges of neurons, leading to the activation of inflammatory responses that in turn contributes to seizure progression." | 5.56 | Anti-Inflammation Associated Protective Mechanism of Berberine and its Derivatives on Attenuating Pentylenetetrazole-Induced Seizures in Zebrafish. ( Ji, X; Jin, M; Liu, K; Sik, A; Wang, L; Zhang, B; Zhang, S, 2020) |
| " Berberine (BBR), an isoquinoline alkaloid, has shown promising effect in the kindling model of epileptogenesis, but due to the poor oral bioavailability its clinical application is limited." | 1.91 | Neuroprotective effect of Berberine Nanoparticles Against Seizures in Pentylenetetrazole Induced Kindling Model of Epileptogenesis: Role of Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Mechanisms. ( Bhatia, A; Bhattacharya, S; Chakrabarti, A; Gautam, V; Kumari, P; Rawat, K; Saha, L; Sandhu, A; Singh, N; Sinha, VR, 2023) |
| "Epileptic seizures are characterized by synchronized discharges of neurons, leading to the activation of inflammatory responses that in turn contributes to seizure progression." | 1.56 | Anti-Inflammation Associated Protective Mechanism of Berberine and its Derivatives on Attenuating Pentylenetetrazole-Induced Seizures in Zebrafish. ( Ji, X; Jin, M; Liu, K; Sik, A; Wang, L; Zhang, B; Zhang, S, 2020) |
| "The antiseizure activity of BERB was shown previously in experimental epilepsy models." | 1.56 | The Influence of Palmatine Isolated from ( Banono, NS; Ent, WV; Esguerra, CV; Gawel, K; Kukula-Koch, W; Nieoczym, D; Stepnik, K; Tarabasz, D; Turski, WA, 2020) |
| "The latency for development of convulsions and mortality rate was recorded in these models using mice." | 1.36 | Anticonvulsant activity of berberine, an isoquinoline alkaloid in mice. ( Bansod, K; Bhutada, P; Dixit, P; Mundhada, D; Mundhada, Y; Umathe, S, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saha, L | 1 |
| Kumari, P | 1 |
| Rawat, K | 1 |
| Gautam, V | 1 |
| Sandhu, A | 1 |
| Singh, N | 1 |
| Bhatia, A | 1 |
| Bhattacharya, S | 1 |
| Sinha, VR | 1 |
| Chakrabarti, A | 1 |
| Zhang, B | 1 |
| Wang, L | 1 |
| Ji, X | 1 |
| Zhang, S | 1 |
| Sik, A | 1 |
| Liu, K | 1 |
| Jin, M | 1 |
| Gawel, K | 1 |
| Kukula-Koch, W | 1 |
| Nieoczym, D | 1 |
| Stepnik, K | 1 |
| Ent, WV | 1 |
| Banono, NS | 1 |
| Tarabasz, D | 1 |
| Turski, WA | 1 |
| Esguerra, CV | 1 |
| Bhutada, P | 1 |
| Mundhada, Y | 1 |
| Bansod, K | 1 |
| Dixit, P | 1 |
| Umathe, S | 1 |
| Mundhada, D | 1 |
4 other studies available for berberine and Seizures
| Article | Year |
|---|---|
Neuroprotective effect of Berberine Nanoparticles Against Seizures in Pentylenetetrazole Induced Kindling Model of Epileptogenesis: Role of Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Mechanisms.
Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Berberine; Kindling, Neurologic; Male; Neuroprot | 2023 |
Anti-Inflammation Associated Protective Mechanism of Berberine and its Derivatives on Attenuating Pentylenetetrazole-Induced Seizures in Zebrafish.
Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Berberine; Female; Macrophages; Male; Pentylenet | 2020 |
The Influence of Palmatine Isolated from
Topics: Animals; Behavior, Animal; Berberine; Berberine Alkaloids; Berberis; Blood-Brain Barrier; Brain-Deri | 2020 |
Anticonvulsant activity of berberine, an isoquinoline alkaloid in mice.
Topics: Animals; Anticonvulsants; Berberine; Diazepam; Disease Models, Animal; Dose-Response Relationship, D | 2010 |