Page last updated: 2024-10-27

fusaric acid and Seizures

fusaric acid has been researched along with Seizures in 2 studies

Fusaric Acid: A picolinic acid derivative isolated from various Fusarium species. It has been proposed for a variety of therapeutic applications but is primarily used as a research tool. Its mechanisms of action are poorly understood. It probably inhibits DOPAMINE BETA-HYDROXYLASE, the enzyme that converts dopamine to norepinephrine. It may also have other actions, including the inhibition of cell proliferation and DNA synthesis.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"An In Vivo model is presented to determine the effects of alpha methyl-para-tyrosine methyl ester (MPT), fusaric acid (FA), and haloperidol on nomifensine-induced seizures."7.67Delay of nomifensine-induced seizures by fusaric acid, alpha-methyltyrosine and haloperidol. ( Huff, MR; Johnson, WE; Meadows, GG, 1986)
"An In Vivo model is presented to determine the effects of alpha methyl-para-tyrosine methyl ester (MPT), fusaric acid (FA), and haloperidol on nomifensine-induced seizures."3.67Delay of nomifensine-induced seizures by fusaric acid, alpha-methyltyrosine and haloperidol. ( Huff, MR; Johnson, WE; Meadows, GG, 1986)
" The administration of 5-hydroxytryptophan with MK486 markedly depressed the incidence of seizures in the E1 mouse."3.66Brain monoamine levels and E1 mouse convulsions. ( Hiramatsu, M, 1981)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hiramatsu, M1
Huff, MR1
Meadows, GG1
Johnson, WE1

Other Studies

2 other studies available for fusaric acid and Seizures

ArticleYear
Brain monoamine levels and E1 mouse convulsions.
    Folia psychiatrica et neurologica japonica, 1981, Volume: 35, Issue:3

    Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Brain; Dioxoles; Dopamine; Evoked Potentials; Fu

1981
Delay of nomifensine-induced seizures by fusaric acid, alpha-methyltyrosine and haloperidol.
    Research communications in chemical pathology and pharmacology, 1986, Volume: 51, Issue:3

    Topics: Animals; Brain; Dopamine; Fusaric Acid; Haloperidol; Male; Methyltyrosines; Nomifensine; Norepinephr

1986