fusaric acid and Seizures
fusaric acid has been researched along with Seizures in 2 studies
Fusaric Acid: A picolinic acid derivative isolated from various Fusarium species. It has been proposed for a variety of therapeutic applications but is primarily used as a research tool. Its mechanisms of action are poorly understood. It probably inhibits DOPAMINE BETA-HYDROXYLASE, the enzyme that converts dopamine to norepinephrine. It may also have other actions, including the inhibition of cell proliferation and DNA synthesis.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "An In Vivo model is presented to determine the effects of alpha methyl-para-tyrosine methyl ester (MPT), fusaric acid (FA), and haloperidol on nomifensine-induced seizures." | 7.67 | Delay of nomifensine-induced seizures by fusaric acid, alpha-methyltyrosine and haloperidol. ( Huff, MR; Johnson, WE; Meadows, GG, 1986) |
| "An In Vivo model is presented to determine the effects of alpha methyl-para-tyrosine methyl ester (MPT), fusaric acid (FA), and haloperidol on nomifensine-induced seizures." | 3.67 | Delay of nomifensine-induced seizures by fusaric acid, alpha-methyltyrosine and haloperidol. ( Huff, MR; Johnson, WE; Meadows, GG, 1986) |
| " The administration of 5-hydroxytryptophan with MK486 markedly depressed the incidence of seizures in the E1 mouse." | 3.66 | Brain monoamine levels and E1 mouse convulsions. ( Hiramatsu, M, 1981) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Hiramatsu, M | 1 |
| Huff, MR | 1 |
| Meadows, GG | 1 |
| Johnson, WE | 1 |
Other Studies
2 other studies available for fusaric acid and Seizures
| Article | Year |
|---|---|
Brain monoamine levels and E1 mouse convulsions.
Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Brain; Dioxoles; Dopamine; Evoked Potentials; Fu | 1981 |
Delay of nomifensine-induced seizures by fusaric acid, alpha-methyltyrosine and haloperidol.
Topics: Animals; Brain; Dopamine; Fusaric Acid; Haloperidol; Male; Methyltyrosines; Nomifensine; Norepinephr | 1986 |