homovanillic acid has been researched along with Seizures in 34 studies
Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the effect of striatal dopamine depletion induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice on kainic acid (KA) evoked seizures." | 7.69 | Motor expression of kainic acid seizures is attenuated by dopamine depletion in mice. ( Bonuccelli, U; Fariello, R; Garant, DS; Maggio, R, 1994) |
| "Little is known about 5-hydroxyindolacetic acid (5-HIAA) and homovanillic acid (HVA) levels in cerebrospinal fluid of patients with Delirium Tremens revealed at onset by seizures." | 5.10 | 5-Hydroxyindolacetic acid and homovanillic acid are not involved in the cerebrospinal fluid after a seizure in patients with Delirium Tremens. ( Beley, P; Couvreur, G; Demougeot, C; Giroud, M; Marie, C; Maugras, C, 2002) |
| "The aim of this work was to analyze the effect of oxcarbazepine (OXC) on sleep patterns, "head and body shakes" and monoamine neurotransmitters level in a model of kainic-induced seizures." | 3.77 | Effects of oxcarbazepine on monoamines content in hippocampus and head and body shakes and sleep patterns in kainic acid-treated rats. ( Alfaro-Rodríguez, A; Arch-Tirado, E; Ávila-Luna, A; Bueno-Nava, A; González-Piña, R; Uribe-Escamilla, R; Vargas-Sánchez, J, 2011) |
| "We studied the effect of striatal dopamine depletion induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice on kainic acid (KA) evoked seizures." | 3.69 | Motor expression of kainic acid seizures is attenuated by dopamine depletion in mice. ( Bonuccelli, U; Fariello, R; Garant, DS; Maggio, R, 1994) |
| "The effects of valproate on CNS concentrations of gamma-aminobutyric acid (GABA), glulamate (GLU), glutamine (GLN); dopamine (DA), serotonin (5-HT), and metabolites were examined in tissue extracts of caudate nucleus of genetic substrains of Balb/c mice susceptible (EP) or resistant (ER) to audiogenic seizures." | 3.69 | Effects of valproate on amino acid and monoamine concentrations in striatum of audiogenic seizure-prone Balb/c mice. ( Alexiuk, NA; Vriend, JP, 1996) |
| " The effects of ECS on 5-HT, 5-HIAA, and HVA were compared to the effects of seizures induced by the convulsant agent flurothyl." | 3.68 | Neurochemical effects of electrically and chemically induced seizures: an in vivo microdialysis study in the rat hippocampus. ( Brown, EE; Damsma, G; Fibiger, HC; Nomikos, GG; Zis, AP, 1992) |
| "Chronic administration of the same dose of cocaine to rhesus monkeys for up to 6 months was associated with progressive alterations in pathological behavior and increased susceptibility to seizures." | 3.65 | Progressive effects of cocaine on behavior and central amine metabolism in rhesus monkeys: relationship to kindling and psychosis. ( Black, KE; Kopanda, RT; Post, RM, 1976) |
| " Rats that did not become hyperthermic when dosed with 15 mg/kg AMPH in a cold environment (10 degrees C) exhibited some hyperactivity and stereotypic behavior, but not overt convulsive behavior." | 1.31 | Seizure activity and hyperthermia potentiate the increases in dopamine and serotonin extracellular levels in the amygdala during exposure to d-amphetamine. ( Bowyer, JF; Tor-Agbidye, J; Yamamoto, B, 2001) |
| "In the seizure animals, neurotransmitter metabolites remained at low levels, as if the hypoxia had continued after the period of ischemia, inhibiting monoamine oxidase activity and, perhaps, neurotransmitter recapture." | 1.29 | Temporal profile of aminergic neurotransmitter release in striatal dialysates in rats with post-ischemic seizures. ( Allain, H; Bellissant, E; Bentué-Ferrer, D; Decombe, R, 1994) |
| "El mouse convulsions were inhibited by oral administration of citalopram for 2 weeks." | 1.29 | The anticonvulsant effect of citalopram on El mice, and the levels of tryptophan and tyrosine and their metabolites in the brain. ( Kabuto, H; Kurimoto, T; Mori, A; Takei, M; Yokoi, I, 1994) |
| "The data suggest that seizure-prone BALB/c mice have a deficiency in intracellular content of both excitatory and inhibitory amino acids." | 1.29 | Determination of amino acids and monoamine neurotransmitters in caudate nucleus of seizure-resistant and seizure-prone BALB/c mice. ( Alexiuk, NA; Green-Johnson, J; Ryan, E; Vriend, J, 1993) |
| "All animals suffered tonic convulsions at 18." | 1.27 | Convulsant effect of lindane and regional brain concentration of GABA and dopamine. ( Gelpí, E; Rodríguez-Farré, E; Suñol, C; Tusell, JM, 1988) |
| "It is postulated that the seizures and neurological deterioration of the patient were related to a deficiency in the synthesis of biogenic amine neurotransmitters." | 1.26 | Biogenic amine synthesis defect in dihydropteridine reductase deficiency. ( Butler, IJ; Koslow, SH, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (41.18) | 18.7374 |
| 1990's | 11 (32.35) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 3 (8.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuśmierska, K | 1 |
| Szymańska, K | 1 |
| Rokicki, D | 1 |
| Kotulska, K | 1 |
| Jóźwiak, S | 1 |
| Sykut-Cegielska, J | 1 |
| Mierzewska, H | 1 |
| Szczepanik, E | 1 |
| Pronicka, E | 1 |
| Demkow, U | 1 |
| Horvath, GA | 1 |
| Demos, M | 1 |
| Shyr, C | 1 |
| Matthews, A | 1 |
| Zhang, L | 1 |
| Race, S | 1 |
| Stockler-Ipsiroglu, S | 1 |
| Van Allen, MI | 1 |
| Mancarci, O | 1 |
| Toker, L | 1 |
| Pavlidis, P | 1 |
| Ross, CJ | 1 |
| Wasserman, WW | 1 |
| Trump, N | 1 |
| Heales, S | 1 |
| Pope, S | 1 |
| Cross, JH | 1 |
| van Karnebeek, CD | 1 |
| Temudo, T | 1 |
| Rios, M | 1 |
| Prior, C | 1 |
| Carrilho, I | 1 |
| Santos, M | 1 |
| Maciel, P | 1 |
| Sequeiros, J | 1 |
| Fonseca, M | 1 |
| Monteiro, J | 1 |
| Cabral, P | 1 |
| Vieira, JP | 1 |
| Ormazabal, A | 1 |
| Artuch, R | 1 |
| Samanta, SK | 1 |
| Kumar, KT | 1 |
| Roy, A | 1 |
| Karmakar, S | 1 |
| Lahiri, S | 1 |
| Palit, G | 1 |
| Vedasiromoni, JR | 1 |
| Sen, T | 1 |
| Alfaro-Rodríguez, A | 1 |
| González-Piña, R | 1 |
| Bueno-Nava, A | 1 |
| Arch-Tirado, E | 1 |
| Ávila-Luna, A | 1 |
| Uribe-Escamilla, R | 1 |
| Vargas-Sánchez, J | 1 |
| Couvreur, G | 1 |
| Demougeot, C | 1 |
| Maugras, C | 1 |
| Marie, C | 1 |
| Beley, P | 1 |
| Giroud, M | 1 |
| Loke, WK | 1 |
| Sim, MK | 1 |
| Go, ML | 1 |
| Georgiev, VP | 1 |
| Klousha, VE | 1 |
| Petkov, VD | 1 |
| Markovska, VL | 1 |
| Svirskis, SV | 1 |
| Mountsinietse, RK | 1 |
| Anouans, ZE | 1 |
| Habel, A | 1 |
| Yates, CM | 1 |
| McQueen, JK | 1 |
| Blackwood, D | 1 |
| Elton, RA | 1 |
| Bentué-Ferrer, D | 1 |
| Bellissant, E | 1 |
| Decombe, R | 1 |
| Allain, H | 1 |
| Kabuto, H | 2 |
| Yokoi, I | 1 |
| Takei, M | 1 |
| Kurimoto, T | 1 |
| Mori, A | 4 |
| Vriend, J | 2 |
| Alexiuk, NA | 3 |
| Green-Johnson, J | 1 |
| Ryan, E | 1 |
| el-Etri, MM | 2 |
| Ennis, M | 2 |
| Jiang, M | 1 |
| Shipley, MT | 2 |
| Dorce, VA | 1 |
| Sandoval, MR | 1 |
| Bonuccelli, U | 1 |
| Garant, DS | 1 |
| Maggio, R | 1 |
| Fariello, R | 1 |
| Vriend, JP | 1 |
| Tor-Agbidye, J | 1 |
| Yamamoto, B | 1 |
| Bowyer, JF | 1 |
| Bourne, JA | 1 |
| Fosbraey, P | 1 |
| Halliday, J | 1 |
| Lewis, D | 1 |
| Isaac, L | 1 |
| Koslow, SH | 1 |
| Butler, IJ | 1 |
| Ohshimo, T | 1 |
| Moskowitz, MA | 1 |
| Wurtman, RJ | 1 |
| Fukuyama, Y | 1 |
| Ochiai, Y | 1 |
| Hayakawa, T | 1 |
| Miyagawa, F | 1 |
| Kobayashi, K | 1 |
| Kariya, T | 1 |
| Post, RM | 1 |
| Kopanda, RT | 1 |
| Black, KE | 1 |
| Zis, AP | 2 |
| Nomikos, GG | 2 |
| Brown, EE | 1 |
| Damsma, G | 2 |
| Fibiger, HC | 2 |
| Nickell, WT | 1 |
| Skau, KA | 1 |
| Hiramatsu, M | 1 |
| Marescau, B | 1 |
| Suñol, C | 1 |
| Tusell, JM | 1 |
| Gelpí, E | 1 |
| Rodríguez-Farré, E | 1 |
| Hino, K | 1 |
| Nagai, Y | 1 |
| Uno, H | 1 |
| Masuda, Y | 1 |
| Oka, M | 1 |
| Karasawa, T | 1 |
2 reviews available for homovanillic acid and Seizures
| Article | Year |
|---|---|
Catecholamines and neurologic diseases (second of two parts).
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Brain; Brain Diseases; Catecholamines; Cereb | 1975 |
Brain monoamines in seizure mechanism (review).
Topics: Animals; Brain; Carbonic Anhydrase Inhibitors; Catecholamines; Child; Dextroamphetamine; Dopamine; E | 1977 |
2 trials available for homovanillic acid and Seizures
| Article | Year |
|---|---|
Evaluation of CSF neurotransmitters and folate in 25 patients with Rett disorder and effects of treatment.
Topics: Administration, Oral; Child; Child, Preschool; DNA Mutational Analysis; Female; Fluoxetine; Folic Ac | 2009 |
5-Hydroxyindolacetic acid and homovanillic acid are not involved in the cerebrospinal fluid after a seizure in patients with Delirium Tremens.
Topics: Adult; Aged; Alcohol Withdrawal Delirium; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; | 2002 |
30 other studies available for homovanillic acid and Seizures
| Article | Year |
|---|---|
Age and Gender-Related Changes in Biogenic Amine Metabolites in Cerebrospinal Fluid in Children.
Topics: Adolescent; Age Factors; Case-Control Studies; Child; Child, Preschool; Dopamine; Female; Homovanill | 2016 |
Secondary neurotransmitter deficiencies in epilepsy caused by voltage-gated sodium channelopathies: A potential treatment target?
Topics: Autistic Disorder; Channelopathies; Child; Drug Resistant Epilepsy; Epilepsy; Exome; Female; Homovan | 2016 |
An insight on the neuropharmacological activity of Telescopium telescopium--a mollusc from the Sunderban mangrove.
Topics: Animals; Behavior, Animal; Body Temperature; Brain; Central Nervous System Depressants; Disease Mode | 2008 |
Effects of oxcarbazepine on monoamines content in hippocampus and head and body shakes and sleep patterns in kainic acid-treated rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Dopamine; Hippocampus; Homovanillic | 2011 |
Novel neuroprotective effects with O-benzyl derivative of pralidoxime in soman-intoxicated rodents.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Analysis of Variance; Animals; Anticonvulsants; Atrop | 2005 |
Central effects of angiotensin II, its fragment and analogues.
Topics: Angiotensin II; Animals; Apomorphine; Behavior, Animal; Brain; Catalepsy; Catecholamines; Haloperido | 1984 |
Homovanillic acid and 5-hydroxyindoleacetic acid in lumbar cerebrospinal fluid in children with afebrile and febrile convulsions.
Topics: Child; Child, Preschool; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Lumbos | 1981 |
Temporal profile of aminergic neurotransmitter release in striatal dialysates in rats with post-ischemic seizures.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydroxyin | 1994 |
The anticonvulsant effect of citalopram on El mice, and the levels of tryptophan and tyrosine and their metabolites in the brain.
Topics: Animals; Anticonvulsants; Brain; Cerebral Cortex; Citalopram; Corpus Striatum; Hippocampus; Homovani | 1994 |
Determination of amino acids and monoamine neurotransmitters in caudate nucleus of seizure-resistant and seizure-prone BALB/c mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Biogenic Monoamines; Caudate Nucleus; Dopamine | 1993 |
Pilocarpine-induced convulsions in rats: evidence for muscarinic receptor-mediated activation of locus coeruleus and norepinephrine release in cholinolytic seizure development.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Locu | 1993 |
Effects of Tityus serrulatus crude venom on the GABAergic and dopaminergic systems of the rat brain.
Topics: Analysis of Variance; Animals; Brain; Brain Stem; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid | 1994 |
Motor expression of kainic acid seizures is attenuated by dopamine depletion in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dopa | 1994 |
Effects of valproate on amino acid and monoamine concentrations in striatum of audiogenic seizure-prone Balb/c mice.
Topics: Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Biogenic Monoamines; Corpus Striatum; D | 1996 |
Lamotrigine inhibits the in situ activity of tyrosine hydroxylase in striatum of audiogenic seizure-prone and audiogenic seizure-resistant Balb/c mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Animals; Corpus Striatum; Dopamine; Enzyme Inh | 1997 |
Seizure activity and hyperthermia potentiate the increases in dopamine and serotonin extracellular levels in the amygdala during exposure to d-amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Amygdala; Animals; Behavior, Animal; Chromatography, Hi | 2001 |
Changes in striatal electroencephalography and neurochemistry induced by kainic acid seizures are modified by dopamine receptor antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Benzazepines; Corpus Striatum; Dopamine; Dop | 2001 |
Effects of antihistaminic drugs on feline brain monoamine metabolism.
Topics: Animals; Body Temperature; Cats; Diphenhydramine; Dopamine; Electroencephalography; Histamine H1 Ant | 1977 |
Biogenic amine synthesis defect in dihydropteridine reductase deficiency.
Topics: 5-Hydroxytryptophan; Biogenic Amines; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindolea | 1977 |
[Relationship of seizure susceptibility and generalized convulsion to brain monoamine concentration in the kindled cat brain (author's transl)].
Topics: Adolescent; Animals; Biogenic Amines; Brain Chemistry; Electric Stimulation; Homovanillic Acid; Huma | 1978 |
Overnight sleep EEG and cerebrospinal fluid monoamines in seizures induced by movement.
Topics: Child; Electroencephalography; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Lev | 1979 |
[Convulsions and monoamines].
Topics: Animals; Biogenic Amines; Brain Chemistry; Dopamine; Epilepsy; Homovanillic Acid; Mice; Rats; Reserp | 1978 |
[Biochemistry of epilepsy (author's transl)].
Topics: Animals; Biogenic Amines; Brain Chemistry; Catecholamines; Cats; Dopamine; Epilepsy; Guanidines; Hom | 1978 |
Progressive effects of cocaine on behavior and central amine metabolism in rhesus monkeys: relationship to kindling and psychosis.
Topics: Animals; Behavior, Animal; Catalepsy; Cocaine; Female; Haplorhini; Homovanillic Acid; Humans; Hydrox | 1976 |
Neurochemical effects of electrically and chemically induced seizures: an in vivo microdialysis study in the rat hippocampus.
Topics: Acetylcholine; Analysis of Variance; Animals; Dialysis; Electroshock; Flurothyl; Hippocampus; Homova | 1992 |
Brain norepinephrine reductions in soman-intoxicated rats: association with convulsions and AChE inhibition, time course, and relation to other monoamines.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Biogenic Amines; Brain; Cholinesterase In | 1992 |
In vivo neurochemical effects of electroconvulsive shock studied by microdialysis in the rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Brain Chemistry; Choline; Convulsants; Corpu | 1991 |
Effects of emotional stress on E1-mouse convulsions, and their biochemical background.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Dopamine; Homovanillic Acid; Hydroxyindole | 1986 |
Convulsant effect of lindane and regional brain concentration of GABA and dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Dopamine; gamma-Aminobutyric Acid; Hexachl | 1988 |
A novel class of potential central nervous system agents. 3-Phenyl-2-(1-piperazinyl)-5H-1-benzazepines.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Body Temperature Regulation; Brain; E | 1988 |