Compounds > idazoxan
Page last updated: 2024-08-23

idazoxan and Seizures

idazoxan has been researched along with Seizures in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's10 (52.63)18.2507
2000's4 (21.05)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McIntyre, DC; Shin, RS1
de Lanerolle, N; Farber, PR; Scordato, JC; Shouse, MN1
Levin, ED; Timofeeva, OA1
Corcoran, ME; Pelletier, MR1
Alcalde, O; Bier, M; Langer, J; Richkind, M; Shouse, MN; Szymusiak, R1
Amabeoku, G; Chandomba, R1
Amabeoku, GJ1
Alcalde, O; Bier, M; Farber, PR; Langer, J; Moghimi, R; Richkind, M; Shouse, MN; Szymusiak, R2
Jazvinsćak Jembrek, M; Mirković Kos, K; Pericić, D; Svob, D1
Corbett, R; Dunn, RW1
Ball, DM; Jackson, HC; Nutt, DJ1
Bengzon, J; Brundin, P; Kokaia, M; Lindvall, O1
Chen, MJ; Savage, DD; Vigil, A; Weiss, GK1
Durcan, MJ; Linnoila, M; Lister, RG; Nutt, DJ1
Bengzon, J; Kalén, P; Kokaia, M; Lindvall, O1
Bonhaus, DW; McNamara, JO2
Bonhaus, DW; Butler, LS; McNamara, JO; Platt, K1

Other Studies

19 other study(ies) available for idazoxan and Seizures

ArticleYear
Differential noradrenergic influence on seizure expression in genetically Fast and Slow kindling rat strains during massed trial stimulation of the amygdala.
    Neuropharmacology, 2007, Volume: 52, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Analysis of Variance; Animals; Dose-Response Relationship, Radiation; Drug Administration Schedule; Electric Stimulation; Guanfacine; Idazoxan; Kindling, Neurologic; Norepinephrine; Rats; Reaction Time; Seizures

2007
The alpha2 adrenoreceptor agonist clonidine suppresses evoked and spontaneous seizures, whereas the alpha2 adrenoreceptor antagonist idazoxan promotes seizures in amygdala-kindled kittens.
    Brain research, 2007, Mar-16, Volume: 1137, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Animals, Newborn; Cats; Clonidine; Electroencephalography; Female; Functional Laterality; Idazoxan; Kindling, Neurologic; Male; Microinjections; Seizures; Stereotaxic Techniques

2007
Idazoxan blocks the nicotine-induced reversal of the memory impairment caused by the NMDA glutamate receptor antagonist dizocilpine.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 90, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Idazoxan; Maze Learning; Memory; Memory Disorders; Memory, Short-Term; Nicotine; Nicotinic Agonists; Norepinephrine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Synaptic Transmission

2008
Infusions of alpha-2 noradrenergic agonists and antagonists into the amygdala: effects on kindling.
    Brain research, 1993, Dec-31, Volume: 632, Issue:1-2

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Benzazepines; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Functional Laterality; Idazoxan; Infusions, Parenteral; Kindling, Neurologic; Male; Rats; Receptors, Adrenergic, alpha-2; Seizures; Xylazine; Yohimbine

1993
The alpha 2-agonist clonidine suppresses seizures, whereas the alpha 2-antagonist idazoxan promotes seizures--a microinfusion study in amygdala-kindled kittens.
    Brain research, 1994, Jun-20, Volume: 648, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Amygdala; Animals; Anticonvulsants; Cats; Clonidine; Convulsants; Dioxanes; Electrodes, Implanted; Electrophysiology; Epilepsy, Tonic-Clonic; Female; Idazoxan; Kindling, Neurologic; Male; Microinjections; Seizures

1994
Strychnine-induced seizures in mice: the role of noradrenaline.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Disulfiram; Droxidopa; Idazoxan; Imipramine; Male; Mice; Pargyline; Phentolamine; Prazosin; Propranolol; Receptors, Adrenergic; Reserpine; Seizures; Strychnine

1994
The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice.
    Experientia, 1993, Oct-15, Volume: 49, Issue:10

    Topics: 5-Hydroxytryptophan; Acetylcholine; alpha-Methyltyrosine; Animals; Atropine; Clonidine; Dioxanes; Droxidopa; Drug Synergism; Idazoxan; Imipramine; Male; Methyltyrosines; Mice; Norepinephrine; Pargyline; Phentolamine; Physostigmine; Prazosin; Reserpine; Seizures; Serotonin

1993
The alpha 2-adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2-adrenoreceptor antagonist idazoxan promotes seizures in amygdala-kindled kittens: a comparison of amygdala and pontine microinfusion effects.
    Epilepsia, 1996, Volume: 37, Issue:8

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Cats; Clonidine; Dioxanes; Disease Susceptibility; Electrodes, Implanted; Epilepsy; Female; Functional Laterality; Idazoxan; Imidazoles; Kindling, Neurologic; Locus Coeruleus; Male; Microinjections; Norepinephrine; Seizures; Stereotaxic Techniques

1996
The alpha 2 adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2 adrenoreceptor antagonist idazoxan promotes seizures: pontine microinfusion studies of amygdala-kindled kittens.
    Brain research, 1996, Aug-26, Volume: 731, Issue:1-2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Age Factors; Amygdala; Animals; Cats; Clonidine; Electric Stimulation; Idazoxan; Kindling, Neurologic; Microelectrodes; Microinjections; Norepinephrine; Pons; Seizures; Sympatholytics

1996
The involvement of alpha2-adrenoceptors in the anticonvulsive effect of swim stress in mice.
    Psychopharmacology, 2001, Volume: 158, Issue:1

    Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Antagonists; Animals; Convulsants; Dihydropyridines; GABA-A Receptor Antagonists; Idazoxan; Infusions, Intravenous; Injections, Intraperitoneal; Male; Mice; Mice, Inbred CBA; Picrotoxin; Receptors, Adrenergic, alpha-2; Seizures; Stress, Physiological; Swimming

2001
Yohimbine-induced seizures involve NMDA and GABAergic transmission.
    Neuropharmacology, 1992, Volume: 31, Issue:4

    Topics: Animals; Bicuculline; Carbolines; Convulsants; Dioxanes; gamma-Aminobutyric Acid; Idazoxan; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Receptors, Adrenergic, alpha; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Synaptic Transmission; Yohimbine

1992
Noradrenergic mechanisms appear not to be involved in cocaine-induced seizures and lethality.
    Life sciences, 1990, Volume: 47, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Cocaine; Desipramine; Dioxanes; Hyperkinesis; Idazoxan; Injections, Intraperitoneal; Mice; Norepinephrine; Seizures

1990
Seizure suppression in kindling epilepsy by intrahippocampal locus coeruleus grafts: evidence for an alpha-2-adrenoreceptor mediated mechanism.
    Experimental brain research, 1990, Volume: 81, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Dioxanes; Dopamine beta-Hydroxylase; Epilepsy; Hippocampus; Hydroxydopamines; Idazoxan; Kindling, Neurologic; Locus Coeruleus; Male; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reference Values; Seizures; Transplantation, Heterotopic

1990
Transient elevation of amygdala alpha 2 adrenergic receptor binding sites during the early stages of amygdala kindling.
    Epilepsy research, 1990, Volume: 5, Issue:2

    Topics: Amygdala; Animals; Autoradiography; Dioxanes; Idazoxan; Kindling, Neurologic; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Seizures

1990
Attenuation of ethanol intoxication by alpha-2 adrenoceptor antagonists.
    Life sciences, 1989, Volume: 44, Issue:2

    Topics: Adrenergic alpha-Antagonists; Alcoholic Intoxication; Animals; Azides; Behavior, Animal; Benzodiazepines; Dioxanes; Ethanol; Idazoxan; Imidazoles; Mice; Receptors, GABA-A; Seizures

1989
Noradrenergic mechanisms in hippocampal kindling with rapidly recurring seizures.
    Brain research, 1989, Jul-10, Volume: 491, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Electric Stimulation; Hippocampus; Hydroxydopamines; Idazoxan; Kindling, Neurologic; Male; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Seizures

1989
Anticonvulsant action of intranigral gamma-vinyl-GABA: role of nonadrenergic neurotransmission.
    Brain research, 1988, Jan-12, Volume: 438, Issue:1-2

    Topics: Aminocaproates; Animals; Anticonvulsants; Dihydroxyphenylalanine; Dioxanes; Dioxins; Idazoxan; Muscimol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Seizures; Spinal Cord; Substantia Nigra; Vigabatrin

1988
Evidence implicating alpha-2 adrenergic receptors in the anticonvulsant action of intranigral muscimol.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:3

    Topics: Animals; Anticonvulsants; Dioxanes; Idazoxan; Kindling, Neurologic; Male; Microinjections; Muscimol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Seizures; Substantia Nigra

1987
Activity of locus coeruleus neurons in amygdala kindled rats: role in the suppression of afterdischarge.
    Brain research, 1987, Mar-24, Volume: 407, Issue:1

    Topics: Action Potentials; Amygdala; Animals; Dioxanes; Electroencephalography; Idazoxan; Kindling, Neurologic; Locus Coeruleus; Male; Norepinephrine; Rats; Rats, Inbred Strains; Seizures

1987