Page last updated: 2024-08-17

2,3,4,6-tetrachlorophenol and Seizures

2,3,4,6-tetrachlorophenol has been researched along with Seizures in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's29 (96.67)2.80

Authors

AuthorsStudies
Pietrafusa, N; Specchio, N; Vigevano, F1
Abou-Khalil, B; Aboumatar, S; Bhatia, P; Biton, V; Klein, P; Krauss, GL; Rosenfeld, WE; Sperling, MR; Vossler, DG; Wechsler, R1
Abou-Khalil, B; Aboumatar, S; Bhatia, P; Biton, V; Ferrari, L; Grall, M; Klein, P; Krauss, GL; Rosenfeld, WE; Sperling, MR; Vossler, DG; Wechsler, R1
Biton, V; Halford, JJ; Rosenfeld, WE; Sander, JW; Steinhoff, BJ; Toledo, M1
Privitera, M; Richy, FF; Schabert, VF1
Brigo, F; Del Giovane, C; Lattanzi, S; Russo, E; Silvestrini, M; Striano, P; Trinka, E; Zaccara, G1
Elliott, T; Gienapp, AJ; Ridley-Pryor, T; Wheless, JW1
Karkare, S; Kothare, SV; Shah, YD; Varughese, RT1
Ferrari, L; Kamin, M; Rosenfeld, WE1
Abou-Khalil, B; Aboumatar, S; Klein, P; Krauss, GL; Rosenfeld, WE; Sperling, MR1
Ben-Menachem, E; Brandt, C; García Morales, I; Rosenfeld, WE; Santamarina, E; Serratosa, JM; Steinhoff, BJ1
Aboumatar, S; Biton, V; Ferrari, L; Rosenfeld, WE; Wechsler, R1
Charlier, B; Coglianese, A; Coppola, G; Dal Piaz, F; de Grazia, U; Filippelli, A; Izzo, V; Menna, P; Operto, FF1
Fornari Caprara, AL; Rissardo, JP1
Dhir, A1
Ferrari, L; Nisman, A; Pegan, A; Ursino, J1
Aboumatar, S; Borchert, L; Gelfand, M; Halford, JJ; Kamin, M; Klein, P; Krauss, GL; Rosenfeld, WE; Sperling, MR; Vossler, DG; Wechsler, R1
Chung, SS; French, JA; Kamin, M; Kowalski, J; Krauss, GL; Lee, SK; Maciejowski, M; Mizne, S; Rosenfeld, WE; Sperling, MR1
Brigo, F; Del Giovane, C; Lattanzi, S; Silvestrini, M; Striano, P; Trinka, E; Zaccara, G1
Steinhoff, BJ1
Campbell, A; Guignet, M; White, HS1
Główka, FK; Karaźniewcz-Łada, M; Sommerfeld-Klatta, K; Zielińska-Psuja, B1
Coe, P; Elizebath, R; Gutierrez, EG; Krauss, GL; Yang, J; Zhang, E1
Cutillo, G; Hirsch, LJ; Tolba, H1
Ferrari, L; Nisman, A; Rosenfeld, WE1
Wang, C; Wang, J; Zhang, L1
Klein, P; Löscher, W1
Chung, SS; French, JA; Kamin, M; Krauss, GL; Lee, SK; Maciejowski, M; Rosenfeld, WE; Sperling, MR1
Bartholini, G; Depoortere, H; Lloyd, KG; Sanger, D; Zivkovic, B1

Reviews

12 review(s) available for 2,3,4,6-tetrachlorophenol and Seizures

ArticleYear
Is Cenobamate the Breakthrough We Have Been Wishing for?
    International journal of molecular sciences, 2021, Aug-28, Volume: 22, Issue:17

    Topics: Anticonvulsants; Carbamates; Chlorophenols; Epilepsy; Humans; Seizures; Tetrazoles

2021
Indirect treatment comparison of cenobamate to other ASMs for the treatment of uncontrolled focal seizures.
    Epilepsy & behavior : E&B, 2022, Volume: 126

    Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Randomized Controlled Trials as Topic; Seizures; Tetrazoles; Treatment Outcome

2022
Third-Generation Antiseizure Medications for Adjunctive Treatment of Focal-Onset Seizures in Adults: A Systematic Review and Network Meta-analysis.
    Drugs, 2022, Volume: 82, Issue:2

    Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Dibenzazepines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lacosamide; Male; Middle Aged; Network Meta-Analysis; Nitriles; Pyridones; Pyrrolidinones; Randomized Controlled Trials as Topic; Seizures; Tetrazoles

2022
Cenobamate (YKP3089) and Drug-Resistant Epilepsy: A Review of the Literature.
    Medicina (Kaunas, Lithuania), 2023, Jul-28, Volume: 59, Issue:8

    Topics: Animals; Carbamates; Chlorophenols; Drug Resistant Epilepsy; Seizures; Tetrazoles; United States

2023
Adjunctive Cenobamate for Focal-Onset Seizures in Adults: A Systematic Review and Meta-Analysis.
    CNS drugs, 2020, Volume: 34, Issue:11

    Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Drug Therapy, Combination; Epilepsy; Humans; Randomized Controlled Trials as Topic; Seizures; Tetrazoles; Treatment Outcome

2020
Cenobamate (Xcopri) for focal seizures.
    The Medical letter on drugs and therapeutics, 2020, 08-24, Volume: 62, Issue:1605

    Topics: Anticonvulsants; Carbamates; Chlorophenols; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Seizures; Tetrazoles

2020
[Cenobamate-a new perspective for epilepsy treatment].
    Der Nervenarzt, 2021, Volume: 92, Issue:2

    Topics: Anticonvulsants; Carbamates; Chlorophenols; Epilepsy; Humans; Seizures; Tetrazoles

2021
Cenobamate (XCOPRI): Can preclinical and clinical evidence provide insight into its mechanism of action?
    Epilepsia, 2020, Volume: 61, Issue:11

    Topics: Animals; Anticonvulsants; Carbamates; Chlorophenols; Drug Evaluation, Preclinical; Humans; Randomized Controlled Trials as Topic; Seizures; Tetrazoles

2020
New Methods Used in Pharmacokinetics and Therapeutic Monitoring of the First and Newer Generations of Antiepileptic Drugs (AEDs).
    Molecules (Basel, Switzerland), 2020, Nov-02, Volume: 25, Issue:21

    Topics: Anticonvulsants; Carbamates; Chlorophenols; Drug Monitoring; Humans; Seizures; Tetrazoles

2020
Anti-seizure medications and efficacy against focal to bilateral tonic-clonic seizures: A systematic review with relevance for SUDEP prevention.
    Epilepsy & behavior : E&B, 2021, Volume: 117

    Topics: Anticonvulsants; Carbamates; Chlorophenols; Epilepsy, Tonic-Clonic; Humans; Seizures; Sudden Unexpected Death in Epilepsy; Tetrazoles

2021
Efficacy and safety of cenobamate in patients with uncontrolled focal seizures: A meta-analysis.
    Acta neurologica Scandinavica, 2021, Volume: 144, Issue:1

    Topics: Anticonvulsants; Carbamates; Chlorophenols; Dizziness; Dose-Response Relationship, Drug; Drug Resistant Epilepsy; Fatigue; Humans; Nausea; Randomized Controlled Trials as Topic; Seizures; Tetrazoles; Treatment Outcome; Vertigo

2021
The Pharmacology and Clinical Efficacy of Antiseizure Medications: From Bromide Salts to Cenobamate and Beyond.
    CNS drugs, 2021, Volume: 35, Issue:9

    Topics: Animals; Anticonvulsants; Bromides; Carbamates; Chlorophenols; Drug Therapy, Combination; Epilepsy; Humans; Salts; Seizures; Tetrazoles; Treatment Outcome

2021

Trials

8 trial(s) available for 2,3,4,6-tetrachlorophenol and Seizures

ArticleYear
Long-term individual retention with cenobamate in adults with focal seizures: Pooled data from the clinical development program.
    Epilepsia, 2022, Volume: 63, Issue:1

    Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Seizures; Tetrazoles; Treatment Outcome

2022
Onset of efficacy and adverse events during Cenobamate titration period.
    Acta neurologica Scandinavica, 2022, Volume: 146, Issue:3

    Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Drug Therapy, Combination; Epilepsies, Partial; Humans; Quality of Life; Seizures; Tetrazoles; Treatment Outcome

2022
Post hoc analysis of a phase 3 study for treatment of uncontrolled focal seizures: Adjunctive cenobamate dose and seizure reduction by baseline seizure frequency.
    Epilepsy research, 2022, Volume: 186

    Topics: Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Seizures; Tetrazoles; Treatment Outcome

2022
Cenobamate (YKP3089) as adjunctive treatment for uncontrolled focal seizures in a large, phase 3, multicenter, open-label safety study.
    Epilepsia, 2020, Volume: 61, Issue:6

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Seizures; Tetrazoles; Treatment Outcome; Young Adult

2020
Randomized phase 2 study of adjunctive cenobamate in patients with uncontrolled focal seizures.
    Neurology, 2020, 06-02, Volume: 94, Issue:22

    Topics: Adolescent; Adult; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Seizures; Tetrazoles; Young Adult

2020
Cenobamate treatment of focal-onset seizures: Quality of life and outcome during up to eight years of treatment.
    Epilepsy & behavior : E&B, 2021, Volume: 116

    Topics: Adolescent; Adult; Anticonvulsants; Carbamates; Chlorophenols; Humans; Quality of Life; Seizures; Tetrazoles; Treatment Outcome

2021
Efficacy of adjunctive cenobamate based on number of concomitant antiseizure medications, seizure frequency, and epilepsy duration at baseline: A post-hoc analysis of a randomized clinical study.
    Epilepsy research, 2021, Volume: 172

    Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Humans; Seizures; Tetrazoles; Treatment Outcome

2021
Long-term safety of adjunctive cenobamate in patients with uncontrolled focal seizures: Open-label extension of a randomized clinical study.
    Epilepsia, 2021, Volume: 62, Issue:9

    Topics: Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Seizures; Tetrazoles; Treatment Outcome

2021

Other Studies

10 other study(ies) available for 2,3,4,6-tetrachlorophenol and Seizures

ArticleYear
Post hoc analysis of a phase 3, multicenter, open-label study of cenobamate for treatment of uncontrolled focal seizures: Effects of dose adjustments of concomitant antiseizure medications.
    Epilepsia, 2021, Volume: 62, Issue:12

    Topics: Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Seizures; Tetrazoles; Treatment Outcome

2021
Efficacy of cenobamate for uncontrolled focal seizures: Post hoc analysis of a Phase 3, multicenter, open-label study.
    Epilepsia, 2021, Volume: 62, Issue:12

    Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Seizures; Tetrazoles; Treatment Outcome

2021
Initial Real-World Experience With Cenobamate in Adolescents and Adults: A Single Center Experience.
    Pediatric neurology, 2022, Volume: 129

    Topics: Adolescent; Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Exanthema; Humans; Retrospective Studies; Seizures; Tetrazoles; Treatment Outcome; Young Adult

2022
Adjunctive use of cenobamate for pediatric refractory focal-onset epilepsy: A single-center retrospective study.
    Epilepsy & behavior : E&B, 2022, Volume: 130

    Topics: Adolescent; Adult; Anticonvulsants; Carbamates; Child; Chlorophenols; Drug Resistant Epilepsy; Epilepsies, Partial; Epilepsy; Humans; Retrospective Studies; Seizures; Tetrazoles; Treatment Outcome

2022
Efficacy of cenobamate by focal seizure subtypes: Post-hoc analysis of a phase 3, multicenter, open-label study.
    Epilepsy research, 2022, Volume: 183

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Caffeine; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Humans; Middle Aged; Seizures; Tetrazoles; Treatment Outcome; Young Adult

2022
Efficacy of cenobamate for uncontrolled focal seizures in patients with previous epilepsy-related surgery: Post hoc analysis of a phase 3, multicenter, open-label study.
    Epilepsy research, 2022, Volume: 184

    Topics: Anticonvulsants; Carbamates; Chlorophenols; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Humans; Seizures; Tetrazoles; Treatment Outcome

2022
Development and Validation of a UHPLC-MS/MS-Based Method to Quantify Cenobamate in Human Plasma Samples.
    Molecules (Basel, Switzerland), 2022, Oct-28, Volume: 27, Issue:21

    Topics: Carbamates; Chlorophenols; Chromatography, High Pressure Liquid; Humans; Seizures; Tandem Mass Spectrometry

2022
Cenobamate for the treatment of focal epilepsy.
    Drugs of today (Barcelona, Spain : 1998), 2020, Volume: 56, Issue:4

    Topics: Adult; Anticonvulsants; Carbamates; Chlorophenols; Epilepsies, Partial; Humans; Seizures; Tetrazoles

2020
An Ex Vivo Evaluation of Cenobamate Administered via Enteral Tubes.
    Drugs in R&D, 2020, Volume: 20, Issue:2

    Topics: Administration, Oral; Anticonvulsants; Carbamates; Chlorophenols; Enteral Nutrition; Humans; Seizures; Tablets; Tetrazoles

2020
Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Bicuculline; Chlorophenols; Clomipramine; Depressive Disorder; Disease Models, Animal; gamma-Aminobutyric Acid; Imipramine; Male; Olfactory Bulb; Rats; Receptors, GABA-A; Seizures; Sleep

1987