Page last updated: 2024-08-23

vx and Seizures

vx has been researched along with Seizures in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's2 (14.29)18.2507
2000's3 (21.43)29.6817
2010's8 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bealer, SL; Dudek, FE; Ekstrand, JJ; Lehmkuhle, MJ; McDonough, JH; Miller-Smith, SM; Scholl, EA1
Ardinger, C; Dunn, E; Haines, K; Lee-Stubbs, R; Matson, L; McCarren, H; McDonough, J; Miller-Smith, S; Whitten, K1
Aas, P; Enger, S; Mariussen, E; Myhrer, T1
Bennett, JP; Bennett, WS; Chambers, HW; Chambers, JE; Leach, CA; Meek, EC; Pringle, RB; Wills, RW1
Clark, MG; Finneran, K; Hilmas, CJ; Poole, MJ; Williams, PT1
McDonough, JH; Shih, TM; Skovira, JW1
McDonough, JH; O'Donnell, JC; Shih, TM2
Guarisco, JA; Kan, RK; McDonough, JH; Myers, TM; Shih, TM1
Chambers, HW; Chambers, JE; Meek, EC; Pringle, RB1
Grauer, E; Levy, A1
Belkin, M; Solberg, Y1
Bajgar, J1
McDonough, JH; McLeod, CG; Nipwoda, MT1

Reviews

1 review(s) available for vx and Seizures

ArticleYear
The role of excitotoxicity in organophosphorous nerve agents central poisoning.
    Trends in pharmacological sciences, 1997, Volume: 18, Issue:6

    Topics: Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Convulsants; Excitatory Amino Acid Antagonists; Humans; Neurons; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Receptors, N-Methyl-D-Aspartate; Sarin; Seizures; Soman; Synaptic Transmission

1997

Other Studies

13 other study(ies) available for vx and Seizures

ArticleYear
Age-dependent behaviors, seizure severity and neuronal damage in response to nerve agents or the organophosphate DFP in immature and adult rats.
    Neurotoxicology, 2018, Volume: 66

    Topics: Animals; Behavior, Animal; Brain; Female; Isoflurophate; Male; Nerve Agents; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Seizures

2018
Evaluation of first-line anticonvulsants to treat nerve agent-induced seizures and prevent neuropathology in adult and pediatric rats.
    Neurotoxicology, 2019, Volume: 74

    Topics: Aging; Animals; Animals, Newborn; Anticonvulsants; Diazepam; Dose-Response Relationship, Drug; Electrocorticography; Female; Male; Midazolam; Nerve Agents; Nervous System Diseases; Neuroprotective Agents; Organothiophosphorus Compounds; Pregnancy; Rats; Rats, Sprague-Dawley; Sarin; Seizures; Status Epilepticus

2019
Supralethal poisoning by any of the classical nerve agents is effectively counteracted by procyclidine regimens in rats.
    Neurotoxicology, 2015, Volume: 50

    Topics: Animals; Anticonvulsants; Antidotes; Body Weight; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Lethal Dose 50; Levetiracetam; Male; Nerve Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Piracetam; Procyclidine; Pyridinium Compounds; Rats; Rats, Wistar; Seizures; Soman

2015
Novel substituted phenoxyalkyl pyridinium oximes enhance survival and attenuate seizure-like behavior of rats receiving lethal levels of nerve agent surrogates.
    Toxicology, 2016, Jan-02, Volume: 339

    Topics: Acetylcholinesterase; Animals; Antidotes; Behavior, Animal; Brain; Cholinesterase Inhibitors; Male; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyrrolidines; Rats; Rats, Sprague-Dawley; Seizures; Survival Analysis

2016
Galantamine is a novel post-exposure therapeutic against lethal VX challenge.
    Toxicology and applied pharmacology, 2009, Oct-15, Volume: 240, Issue:2

    Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diaphragm; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Erythrocytes; Galantamine; Guinea Pigs; Male; Muscle Fatigue; Muscle Tonus; Neurotoxicity Syndromes; Organothiophosphorus Compounds; Paralysis; Phrenic Nerve; Pralidoxime Compounds; Seizures; Time Factors

2009
Effects of 4-pyridine aldoxime on nerve agent-inhibited acetylcholinesterase activity in guinea pigs.
    Archives of toxicology, 2009, Volume: 83, Issue:12

    Topics: Acetylcholinesterase; Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Longevity; Male; Neurotoxicity Syndromes; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Salivation; Sarin; Seizures; Tears

2009
Changes in extracellular striatal acetylcholine and brain seizure activity following acute exposure to nerve agents in freely moving guinea pigs.
    Toxicology mechanisms and methods, 2010, Volume: 20, Issue:3

    Topics: Acetylcholine; Animals; Brain; Chemical Warfare Agents; Choline; Cholinesterase Inhibitors; Corpus Striatum; Electroencephalography; Guinea Pigs; Male; Organothiophosphorus Compounds; Sarin; Seizures; Soman

2010
The oxime pro-2-PAM provides minimal protection against the CNS effects of the nerve agents sarin, cyclosarin, and VX in guinea pigs.
    Toxicology mechanisms and methods, 2011, Volume: 21, Issue:1

    Topics: Animals; Cholinesterase Reactivators; Guinea Pigs; Male; Organophosphorus Compounds; Organothiophosphorus Compounds; Pralidoxime Compounds; Prodrugs; Sarin; Seizures

2011
In vivo microdialysis and electroencephalographic activity in freely moving guinea pigs exposed to organophosphorus nerve agents sarin and VX: analysis of acetylcholine and glutamate.
    Archives of toxicology, 2011, Volume: 85, Issue:12

    Topics: Acetylcholine; Animals; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Electroencephalography; Glutamic Acid; Guinea Pigs; Male; Microdialysis; Multivariate Analysis; Organothiophosphorus Compounds; Sarin; Seizures; Severity of Illness Index

2011
Testing of novel brain-penetrating oxime reactivators of acetylcholinesterase inhibited by nerve agent surrogates.
    Chemico-biological interactions, 2013, Mar-25, Volume: 203, Issue:1

    Topics: Acetylcholinesterase; Animals; Blood-Brain Barrier; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Evaluation, Preclinical; GPI-Linked Proteins; Male; Organophosphates; Organothiophosphorus Compounds; Oximes; Rats; Rats, Sprague-Dawley; Sarin; Seizures

2013
Oxotremorine-induced hypothermia as a method for evaluating long-term neuronal changes following poisoning by cholinesterase inhibitors in rats.
    Toxicology, 2007, Dec-05, Volume: 242, Issue:1-3

    Topics: Aldicarb; Animals; Body Temperature; Carbamates; Central Nervous System; Cholinesterase Inhibitors; Disease Models, Animal; Hypothermia; Lethal Dose 50; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Organophosphorus Compounds; Organothiophosphorus Compounds; Oxotremorine; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Recovery of Function; Reproducibility of Results; Sarin; Seizures; Time Factors; Toxicity Tests

2007
Biological monitoring of exposure to nerve agents.
    British journal of industrial medicine, 1992, Volume: 49, Issue:9

    Topics: Acetylcholinesterase; Animals; Brain; Diaphragm; Dogs; Organophosphorus Compounds; Organothiophosphorus Compounds; Rats; Salivation; Sarin; Seizures; Soman

1992
Direct microinjection of soman or VX into the amygdala produces repetitive limbic convulsions and neuropathology.
    Brain research, 1987, Dec-01, Volume: 435, Issue:1-2

    Topics: Amygdala; Animals; Brain; Convulsants; Male; Microinjections; Organothiophosphorus Compounds; Rats; Rats, Inbred Strains; Seizures; Soman

1987