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meclofenamic acid and Seizures

meclofenamic acid has been researched along with Seizures in 2 studies

Meclofenamic Acid: A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
meclofenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Gap junctions have been implicated in seizure generation and propagation, and as such, may represent a novel therapeutic target but have been little investigated in vivo."1.33Antiepileptic effect of gap-junction blockers in a rat model of refractory focal cortical epilepsy. ( Cock, HR; Kelso, AR; Nilsen, KE, 2006)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nilsen, KE1
Kelso, AR1
Cock, HR1
Wallenstein, MC1

Other Studies

2 other studies available for meclofenamic acid and Seizures

ArticleYear
Antiepileptic effect of gap-junction blockers in a rat model of refractory focal cortical epilepsy.
    Epilepsia, 2006, Volume: 47, Issue:7

    Topics: Administration, Topical; Animals; Anticonvulsants; Behavior, Animal; Carbenoxolone; Cerebral Cortex;

2006
Differential effect of prostaglandin synthetase inhibitor pretreatment on pentylenetetrazol-induced seizures in rat.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 275, Issue:1

    Topics: Acetaminophen; Animals; Behavior, Animal; Cyclooxygenase Inhibitors; Electric Stimulation; Electroen

1985