Page last updated: 2024-10-26

endosulfan and Seizures

endosulfan has been researched along with Seizures in 14 studies

Endosulfan: A polychlorinated compound used for controlling a variety of insects. It is practically water-insoluble, but readily adheres to clay particles and persists in soil and water for several years. Its mode of action involves repetitive nerve-discharges positively correlated to increase in temperature. This compound is extremely toxic to most fish. (From Comp Biochem Physiol (C) 1993 Jul;105(3):347-61)
endosulfan : A cyclic sulfite ester that is 1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide substituted by chloro groups at positions 6, 7, 8, 9, 10 and 10.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Endosulfan poisoning can be suspected in the presence of primary central nervous system manifestations including seizures, with or without clinical or laboratory evidence of other organ dysfunction such as liver failure."3.73Characteristics of endosulfan poisoning: a study of 23 cases. ( Aygun, D; Baydin, A; Karatas, AD, 2006)
"In order to study the response of rats to repeated administration of the insecticide, endosulfan during the period of growth to maturity, food intake, body weight gain, Spontaneous Motor Activity (SMA) and Muscle Coordination (MC) were determined at regular intervals in male immature Wistar rats treated with a tolerated dose of (2 mg/kg/day) orally for 90 days."3.68Behavioural and biochemical changes produced by repeated oral administration of the insecticide endosulfan in immature rats. ( Balasubramaniam, E; Kazi, M; Paul, V; Sheela, S, 1993)
"Endosulfan is an organochloride insecticide, widely used in insect control."1.35Unintentional endosulfan poisoning. ( Alpay, NR; Gumusay, U; Guneysel, O; Satar, S; Sebe, A, 2009)
"Endosulfan is a widely used insecticide that is associated with a high fatality rate in humans when ingested accidentally or with the aim of suicide."1.35Acute endosulfan poisoning: a retrospective study. ( Chun, BJ; Moon, JM, 2009)
"Endosulfan has been banned in many countries; however, it is still used in the United States."1.35Death in a toddler following endosulfan ingestion. ( Parbhu, B; Rodgers, G; Sullivan, JE, 2009)
"Endosulfan is a highly toxic organochlorine insecticide that produces well-known neurological symptoms of tonic-clonic convulsions, headache, dizziness and ataxia but also can cause gastrointestinal symptoms and metabolic disturbances."1.32Acute endosulfan poisoning with cerebral edema and cardiac failure. ( Eyer, F; Felgenhauer, N; Jetzinger, E; Pfab, R; Zilker, TR, 2004)
"The seizure was attributed to exposure to the organochlorine, however, subsequent EEG recordings demonstrated a non-specific epileptiform focus in the frontal lobes."1.30Acute carbamate and organochlorine toxicity causing convulsions in an agricultural pilot: a case report. ( Cable, GG; Doherty, S, 1999)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's3 (21.43)18.2507
2000's7 (50.00)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Durukan, P1
Ozdemir, C1
Coskun, R1
Ikizceli, I1
Esmaoglu, A1
Kurtoglu, S1
Guven, M1
Satar, S1
Sebe, A1
Alpay, NR1
Gumusay, U1
Guneysel, O1
Moon, JM1
Chun, BJ1
Parbhu, B1
Rodgers, G1
Sullivan, JE1
Jindal, A1
Sankhyan, N1
Oktay, C1
Goksu, E1
Bozdemir, N1
Soyuncu, S1
Eyer, F1
Felgenhauer, N1
Jetzinger, E1
Pfab, R1
Zilker, TR1
Karatas, AD1
Aygun, D1
Baydin, A1
Paul, V1
Sheela, S1
Balasubramaniam, E1
Kazi, M1
Cable, GG1
Doherty, S1
Nicholson, SS1
Cooper, GW1
Blanco-Coronado, JL1
Repetto, M1
Ginestal, RJ1
Vicente, JR1
Yelamos, F1
Lardelli, A1
Cole, LM1
Casida, JE1
Shemesh, Y1
Bourvine, A1
Gold, D1
Bracha, P1

Other Studies

14 other studies available for endosulfan and Seizures

ArticleYear
Experiences with endosulfan mass poisoning in rural areas.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2009, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Endosulfan; Female; Gastric Lavage; Humans; Infant

2009
Unintentional endosulfan poisoning.
    Bratislavske lekarske listy, 2009, Volume: 110, Issue:5

    Topics: Endosulfan; Family Health; Female; Food Contamination; Humans; Insecticides; Seizures

2009
Acute endosulfan poisoning: a retrospective study.
    Human & experimental toxicology, 2009, Volume: 28, Issue:5

    Topics: Acute Disease; Acute Kidney Injury; Adolescent; Adult; Aged; Anticonvulsants; Chemical and Drug Indu

2009
Death in a toddler following endosulfan ingestion.
    Clinical toxicology (Philadelphia, Pa.), 2009, Volume: 47, Issue:9

    Topics: Anticonvulsants; Child, Preschool; Endosulfan; Fatal Outcome; Humans; Insecticides; Male; Seizures;

2009
Endosulfan poisoning resulting from skin exposure.
    Indian journal of pediatrics, 2012, Volume: 79, Issue:8

    Topics: Administration, Cutaneous; Animals; Child, Preschool; Endosulfan; Female; Humans; Insecticides; Lice

2012
Unintentional toxicity due to endosulfan: a case report of two patients and characteristics of endosulfan toxicity.
    Veterinary and human toxicology, 2003, Volume: 45, Issue:6

    Topics: Coma; Diagnosis, Differential; Electrocardiography; Emergency Treatment; Endosulfan; Female; Glasgow

2003
Acute endosulfan poisoning with cerebral edema and cardiac failure.
    Journal of toxicology. Clinical toxicology, 2004, Volume: 42, Issue:6

    Topics: Adult; Alcoholism; Arrhythmias, Cardiac; Barbiturates; Brain Edema; Cardiac Output, Low; Endosulfan;

2004
Characteristics of endosulfan poisoning: a study of 23 cases.
    Singapore medical journal, 2006, Volume: 47, Issue:12

    Topics: Adolescent; Adult; Aged; Developing Countries; Endosulfan; Environmental Exposure; Female; Humans; I

2006
Behavioural and biochemical changes produced by repeated oral administration of the insecticide endosulfan in immature rats.
    Indian journal of physiology and pharmacology, 1993, Volume: 37, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Behavior, Animal; Body Weight; Eating; E

1993
Acute carbamate and organochlorine toxicity causing convulsions in an agricultural pilot: a case report.
    Aviation, space, and environmental medicine, 1999, Volume: 70, Issue:1

    Topics: Adult; Aerospace Medicine; Agricultural Workers' Diseases; Diagnosis, Differential; Electroencephalo

1999
Apparent endosulfan toxicosis in calves.
    Journal of the American Veterinary Medical Association, 1977, Feb-01, Volume: 170, Issue:3

    Topics: Animals; Cattle; Cattle Diseases; Endosulfan; Seizures

1977
Acute intoxication by endosulfan.
    Journal of toxicology. Clinical toxicology, 1992, Volume: 30, Issue:4

    Topics: Accidents; Acid-Base Equilibrium; Acidosis; Adult; Endosulfan; Female; Hemodynamics; Humans; Hypergl

1992
Polychlorocycloalkane insecticide-induced convulsions in mice in relation to disruption of the GABA-regulated chloride ionophore.
    Life sciences, 1986, Nov-17, Volume: 39, Issue:20

    Topics: Animals; Binding, Competitive; Brain; Chlorides; Endosulfan; Hydrocarbons, Chlorinated; Insecticides

1986
Survival after acute endosulfan intoxication.
    Journal of toxicology. Clinical toxicology, 1988, Volume: 26, Issue:3-4

    Topics: Adult; Endosulfan; Hemodynamics; Humans; Male; Seizures

1988