enkephalin, leucine has been researched along with Seizures in 94 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 59 (62.77) | 18.7374 |
1990's | 29 (30.85) | 18.2507 |
2000's | 4 (4.26) | 29.6817 |
2010's | 2 (2.13) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Almquist, RG; Olsen, CM; Toll, L; Uyeno, ET | 1 |
Aigner, C; Herzog, H; Schunk, E; Schwarzer, C; Stefanova, N; Wenning, G | 1 |
Einheber, S; Milner, TA; Pierce, JP; Skyers, PS | 1 |
An, JJ; Bae, MH; Baik, JH; Borrelli, E; Cho, SR; Choi, SH; Kim, YN; Lee, BH; Lee, SH; Park, KW; Shin, HS | 1 |
Adrian, R; Baratta, J; Koob, GF; Lauterborn, JC; Solbrig, MV | 1 |
Holaday, JW; Mosberg, HI; Robles, L; Tortella, FC | 1 |
Inoki, R; Kotani, Y; Kudo, T; Oheda, N | 1 |
Albertson, TE; Peterson, SL | 1 |
Costa, E; Gillin, JC; Hong, JS; Wood, PL; Yang, HY | 2 |
Elazar, Z; Motles, E; Simantov, R | 1 |
Bearden, LJ; Snead, OC | 1 |
French, ED; Siggins, GR | 1 |
Adler, MW; Cowan, A; Tortella, FC | 2 |
Bloom, FE; Henriksen, SJ | 1 |
Ackermann, RF; Caldecott-Hazard, S; Engel, J; Frederickson, RC; Liebeskind, JC; Shavit, Y | 1 |
Katz, RJ | 1 |
Macdonald, RL; Werz, MA | 1 |
Belluzzi, JD; Kelsey, JE | 1 |
Barbeau, A; Izumi, K; Munekata, E; Nakanishi, T; Wong, P; Yamamoto, H; Yoshida, M | 1 |
Asai, M; Briones, R; Fernández-Guardiola, A; Vindrola, O | 1 |
Meldrum, BS; Menini, C; Naquet, R; Riche, D; Silva-Comte, C | 1 |
Aloisi, F; Longo, V; Scotti De Carolis, A | 1 |
Kaczmarek, L; Kamińska, B; Lasoń, W; Lukasiuk, K; Nowicka, DZ; Przewłocka, B; Przewłocki, R | 1 |
Applegate, CD; Piekut, DT; Pretel, S | 1 |
Christakos, S; Devinsky, O; Howells, R; Lee, S; Lothman, E; Miskovsky, J; Williamson, J | 1 |
Kim, SY; Post, RM; Rosen, JB | 1 |
Daunais, JB; Helton, TE; McGinty, JF | 1 |
Ackermann, RF; Engel, J; Evans, CJ; Maidment, NT; Rocha, L | 1 |
Erickson, JT; Kanter, RK; Millhorn, DE | 1 |
Lasoń, W; Machelska, H; Przewłocka, B; Przewłocki, R | 1 |
Brusa, L; D'Amore, A; Lorenzini, P; Massotti, M | 1 |
Chang, KJ; Comer, SD; De Costa, BR; Hoenicke, EM; McNutt, RW; Mosberg, HI; Sable, AI; Woods, JH | 1 |
Carter, DA; Murphy, D | 1 |
Beani, L; Bianchi, C; Bregola, G; Donatini, A; Ferri, S; Romualdi, P; Simonato, M | 1 |
Bing, G; Bronstein, D; Hong, JS; Kim, HC; Suh, HW; Wilson, B | 1 |
Banks, WA; Kastin, AJ; Plotkin, SR | 1 |
Fischer-Colbrie, R; Schwarzer, C; Sperk, G; Tsunashima, K; Wolkersdorfer, M | 1 |
Labuz, D; Mika, J; Przewłocka, B; Przewłocki, R; Ziółkowska, B | 1 |
Becker, A; Grecksch, G; Hoellt, V; Schroeder, H; Schroeder, U | 1 |
Banks, WA; Cohn, CS; Kastin, AJ; Plotkin, SR | 1 |
Frenk, H; Liebeskind, JC; McCarty, BC | 1 |
Frenk, H; Liebeskind, JC; Urca, G | 1 |
Ackermann, RF; Engel, J; Frenk, H; Liebeskind, JC; Shavit, Y | 1 |
Meldrum, BS; Menini, C; Naquet, R; Stutzmann, JM | 1 |
Bloom, FE; Guillemin, R; Henriksen, SJ; Ling, N; McCoy, F | 1 |
Eger, EI; Harper, MH; Johnson, BH; Winter, PM | 1 |
Bajorek, JG; Chesarek, W; Felmer, M; Lomax, P | 1 |
Frenk, H; Liebeskind, JC; Taylor, AN; Urca, G | 1 |
Gall, CM; White, JD; Yount, GL | 1 |
Iinuma, K; Onodera, K; Suzuki, T; Watanabe, T; Yokoyama, H | 1 |
Hong, JS | 1 |
Brannock, MT; Donovan, DM; O'Hara, BF; Takemura, M; Uhl, GR | 1 |
Lasoń, W; Przewłocka, B; Przewłocki, R | 2 |
Douglass, J; Grimes, L; Hong, JS; Lee, PH; Shook, J | 1 |
Biguet, NF; Chaminade, M; Fayada, C; Guibert, B; Leviel, V; Machek, G; Mallet, J | 1 |
Echevarria, E; Holaday, JW; Lipkowski, AW; Portoghese, PS; Takemori, AE; Tortella, FC | 1 |
Porreca, F; Tortella, FC | 1 |
Gall, CM; Lauterborn, JC; Pico, RM | 1 |
Grimes, L; Hong, JS; Kanamatsu, T; McGinty, JF; Obie, J; Sabol, S; Yoshikawa, K | 1 |
Holaday, JW; Tortella, FC | 2 |
Gall, C | 1 |
Gall, CM | 1 |
Mosberg, HI; Robles, L; Tortella, FC | 1 |
Gall, CM; White, JD | 1 |
Baudry, M; Gall, C; Lynch, G | 1 |
Corder, CN; Faith, RE; Miller, GC; Murgo, AJ; Plotnikoff, NP | 1 |
Laorden, ML; Miralles, FS; Olaso, MJ; Puig, MM | 1 |
Chai, W; Gao, CJ; Li, YQ; Niu, L; Ren, PC; Sun, XD; Wang, W; Zhu, C | 1 |
Snead, OC | 2 |
Cowan, A; Holaday, JW; Robles, LE; Tortella, FC | 2 |
De Kloet, R; Dzoljic, MR; Haffmans, J | 1 |
Castellano, C; Csányl, V; Dóka, A; Oliverio, A; Puglisi-Allegra, S | 1 |
Snead, OC; Stephens, H | 1 |
Blankwater, YJ; Dzoljic, MR; Haffmans, J; Hespe, W; Ukponmwan, OE; Vincent, JE; Zijlstra, FJ | 1 |
Dzoljic, MR; Haffmans, J | 2 |
Frenk, H; Urca, G | 1 |
Asai, M; Linares, G; Vindrola, O; Zubieta, M | 1 |
Asai, M; Avila, ME; Cano-Martínez, A; Matamoros-Trejo, G; Talavera, E | 1 |
Cheng, T; Hang, RC; Lian, QL; Ni, GT; Qian, BR; Tao, HY | 1 |
Khlebnikova, NN; Kryzhanovskiĭ, GN; Lutsenko, VK | 1 |
Goriacheva, TV; Karganov, MIu; Khlebnikova, NN; Kryzhanovskiĭ, GN; Lutsenko, VK | 1 |
Kawakita, Y; Onishi, H; Soma, T; Yamagami, S | 1 |
Bose, R; Frederickson, RC; Pinsky, C | 1 |
Long, JB; Tortella, FC | 1 |
Holaday, JW; Robles, L; Tortella, FC | 1 |
Walker, GE; Yaksh, TL | 1 |
Kotlińska, J; Langwiński, R | 1 |
3 review(s) available for enkephalin, leucine and Seizures
Article | Year |
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Neurotransmitter and neuromodulator function in the kindled seizure and state.
Topics: Amygdala; Animals; Biogenic Amines; Brain; Convulsants; Cyclic AMP; Cyclic GMP; Electric Stimulation; Enkephalins; gamma-Aminobutyric Acid; Kindling, Neurologic; Neurotransmitter Agents; Rats; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, GABA-A; Seizures | 1982 |
Hippocampal opioid peptides and seizures.
Topics: Afferent Pathways; Amygdala; Animals; Dynorphins; Electric Stimulation; Endorphins; Enkephalins; Gene Expression Regulation; Kindling, Neurologic; Limbic System; Nerve Fibers; Receptors, Opioid; Seizures; Synaptic Transmission | 1992 |
Localization and seizure-induced alterations of opioid peptides and CCK in the hippocampus.
Topics: Animals; Cholecystokinin; Dynorphins; Endorphins; Enkephalins; Hippocampus; Neuropeptides; Protein Precursors; RNA, Messenger; Seizures | 1988 |
91 other study(ies) available for enkephalin, leucine and Seizures
Article | Year |
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Replacement of the peptide-backbone amides connecting Tyr-Gly and Gly-Gly in leucine-enkephalin with ketomethylene groups: synthesis and biological activity.
Topics: Analgesia; Animals; Biological Assay; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Enkephalin, Leucine; Glycine; Mice; Receptors, Opioid; Seizures; Structure-Activity Relationship; Tyrosine | 1984 |
Kappa opioid receptor activation blocks progressive neurodegeneration after kainic acid injection.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; CA1 Region, Hippocampal; Enkephalins; Guanidines; Humans; Interneurons; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphinans; Neurodegenerative Diseases; Protein Precursors; Pyramidal Cells; Receptors, Opioid, kappa; Seizures | 2011 |
Increased mu-opioid receptor labeling is found on inner molecular layer terminals of the dentate gyrus following seizures.
Topics: Animals; Dendrites; Dentate Gyrus; Disease Models, Animal; Enkephalins; Immunohistochemistry; Kainic Acid; Male; Mossy Fibers, Hippocampal; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Seizures | 2003 |
Altered GABAergic neurotransmission in mice lacking dopamine D2 receptors.
Topics: Animals; Basal Ganglia; Brain Chemistry; Dopamine; Electroencephalography; Enkephalins; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Mice; Mice, Knockout; Motor Activity; Neural Inhibition; Receptors, Dopamine D2; Receptors, GABA-A; Seizures; Synaptic Transmission; Up-Regulation | 2004 |
Kappa opioid control of seizures produced by a virus in an animal model.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Blotting, Northern; Borna Disease; Cell Survival; Disease Models, Animal; Dynorphins; Electroencephalography; Encephalitis, Viral; Enkephalins; Hippocampus; Male; Naloxone; Narcotic Antagonists; Neurons; Rats; Rats, Inbred Lew; Receptors, Opioid, kappa; Seizures | 2006 |
Electroencephalographic assessment of the role of delta receptors in opioid peptide - induced seizures.
Topics: Animals; Electroencephalography; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures | 1984 |
[Effects of endogenous peptides administered intracerebroventricularly on acetic acid-induced writhing syndrome in mice. I. Neurotensin, bradykinin, somatostatin and methionine-enkephalin].
Topics: Acetates; Animals; Bradykinin; Enkephalin, Methionine; Enkephalins; Mice; Neurotensin; Peptides; Seizures; Somatostatin | 1980 |
Recurrent convulsions and hippocampal [Met5]-enkephalin content.
Topics: Animals; Electroshock; Endorphins; Enkephalin, Methionine; Enkephalins; Hippocampus; Injections; Kainic Acid; Male; Neurons; Rats; Recurrence; Seizures; Substance P; Time Factors | 1980 |
Influence of body temperature on the epileptogenic effect of enkephalin microinjections into the hippocampus.
Topics: Animals; Body Temperature Regulation; Endorphins; Enkephalin, Leucine; Enkephalins; Evoked Potentials; Hippocampus; Male; Rats; Rats, Inbred Strains; Seizures | 1981 |
Anticonvulsants specific for petit mal antagonize epileptogenic effect of leucine enkephalin.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Endorphins; Enkephalins; Epilepsy, Absence; Ethosuximide; Male; Rats; Receptors, Opioid; Seizures; Trimethadione; Valproic Acid | 1980 |
An iontophoretic survey of opioid peptide actions in the rat limbic system: in search of opiate epileptogenic mechanisms.
Topics: Action Potentials; Amygdala; Animals; beta-Endorphin; Endorphins; Enkephalin, Methionine; Enkephalins; Gyrus Cinguli; Hippocampus; Iontophoresis; Limbic System; Male; Morphine; Neurons; Pressure; Rats; Seizures; Septal Nuclei | 1980 |
Comparison of the anticonvulsant effects of opioid peptides and etorphine in rats after icv administration.
Topics: Animals; Anticonvulsants; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Etorphine; Flurothyl; Male; Morphinans; Naloxone; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1981 |
Endorphin studies: electrophysiologic effects.
Topics: Animals; beta-Endorphin; Brain; Brain Mapping; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Evoked Potentials; Interneurons; Kindling, Neurologic; Neural Inhibition; Neurons; Pituitary Gland; Rats; Receptors, Opioid; Seizures | 1981 |
Behavioral and electrographic effects of opioids on kindled seizures in rats.
Topics: Animals; Behavior, Animal; Drug Tolerance; Enkephalins; Guinea Pigs; Humans; Kindling, Neurologic; Male; Mice; Morphine; Morphine Derivatives; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Vas Deferens | 1982 |
Morphine- and endorphin-induced behavioral activation in the mouse: implications for mania and some recent pharmacogenetic studies.
Topics: Animals; Behavior, Animal; Bipolar Disorder; Disease Models, Animal; Endorphins; Enkephalins; Genetics, Behavioral; Humans; Mice; Morphine; Peromyscus; Running; Seizures | 1982 |
Opiate alkaloids antagonize postsynaptic glycine and GABA responses: correlation with convulsant action.
Topics: Animals; Cells, Cultured; Dextrorphan; Enkephalin, Methionine; Enkephalins; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Levorphanol; Mice; Morphine; Naloxone; Narcotics; Neural Inhibition; Neurons; Seizures; Spinal Cord; Synapses | 1982 |
Endorphin mediation of post-ictal effects of kindled seizures in rats.
Topics: Amygdala; Animals; Enkephalins; Globus Pallidus; Kindling, Neurologic; Male; Naloxone; Rats; Rats, Inbred Strains; Reflex; Seizures | 1982 |
Central neuropharmacology of D-Ala2-Met-enkephalinamide and its interactions with taurine in rats.
Topics: Analgesia; Animals; Catatonia; Corpus Striatum; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Humans; Leucine; Male; Rats; Rats, Inbred Strains; Seizures; Taurine | 1981 |
Amygdaloid kindling enhances the enkephalin content in the rat brain.
Topics: Amygdala; Animals; Brain; Electric Stimulation; Endorphins; Enkephalins; Male; Radioimmunoassay; Rats; Seizures | 1981 |
A comparison of the anticonvulsant effects of two systemically active enkephalin analogues in rats.
Topics: Animals; Anticonvulsants; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Flurothyl; Male; Naloxone; Rats; Seizures | 1981 |
Absence of seizure activity following focal cerebral injection of enkephalins in a primate.
Topics: Amygdala; Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Electroencephalography; Enkephalin, Methionine; Enkephalins; Hippocampus; Injections, Intraventricular; Light; Morphine; Narcotics; Papio; Seizures; Thalamus | 1981 |
Changes of hippocampal Met-enkephalin content after recurrent motor seizures.
Topics: Animals; Endorphins; Enkephalins; Functional Laterality; Hippocampus; Kainic Acid; Male; Phenobarbital; Pyrrolidines; Rats; Seizures; Time Factors | 1980 |
EEG and behavioral effects of morphine, enkephalins and derivatives administered into the lateral cerebral ventricles of rats and rabbits.
Topics: Animals; Behavior, Animal; Cerebral Ventricles; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Electroencephalography; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Injections, Intraventricular; Male; Morphine; Nalorphine; Rabbits; Rats; Seizures | 1980 |
Seizure related changes in the regulation of opioid genes and transcription factors in the dentate gyrus of rat hippocampus.
Topics: Animals; Behavior, Animal; Dentate Gyrus; DNA; Enkephalins; Gene Expression Regulation; Genes, fos; Genes, jun; Kainic Acid; Male; Opioid Peptides; Pentylenetetrazole; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Seizures; Transcription Factor AP-1; Transcription Factors | 1995 |
Seizure-induced activation of enkephalin- and somatostatin-synthesizing neurons.
Topics: Animals; Brain; Enkephalins; Gene Expression Regulation; Kainic Acid; Male; Neurons; Organ Specificity; Rats; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Seizures; Somatostatin | 1995 |
Changes in glutamate receptor and proenkephalin gene expression after kindled seizures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Blotting, Northern; Brain; Cerebellum; DNA Probes; Electric Stimulation; Enkephalins; Frontal Lobe; Gene Expression; Hippocampus; In Situ Hybridization; Kainic Acid; Kindling, Neurologic; Macromolecular Substances; Male; Organ Specificity; Parietal Lobe; Protein Precursors; Rats; Receptors, GABA; Receptors, Glutamate; RNA, Messenger; Seizures; Transcription, Genetic | 1994 |
Differential regional and time course increases in thyrotropin-releasing hormone, neuropeptide Y and enkephalin mRNAs following an amygdala kindled seizure.
Topics: Amygdala; Animals; Base Sequence; Enkephalins; Gene Expression Regulation; Kindling, Neurologic; Male; Molecular Sequence Data; Nerve Tissue Proteins; Neuropeptide Y; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures; Thyrotropin-Releasing Hormone; Time Factors | 1994 |
Convulsant doses of cocaine alter immediate early gene and opioid peptide expression in rat limbic forebrain.
Topics: Animals; Cocaine; Convulsants; DNA-Binding Proteins; Dynorphins; Early Growth Response Protein 1; Enkephalins; Gene Expression Regulation; Immediate-Early Proteins; In Situ Hybridization; Kindling, Neurologic; Limbic System; Male; Nerve Tissue Proteins; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Seizures; Time Factors; Transcription Factors | 1993 |
Microdialysis reveals changes in extracellular opioid peptide levels in the amygdala induced by amygdaloid kindling stimulation.
Topics: Amygdala; Animals; Chromatography, High Pressure Liquid; Electric Stimulation; Electroencephalography; Enkephalins; Kindling, Neurologic; Kinetics; Male; Microdialysis; Potassium; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Seizures; Time Factors | 1994 |
Activation of the c-fos gene in prodynorphin- and proenkephalin-expressing cells of nucleus tractus solitarius after seizures.
Topics: Animals; Enkephalins; Gene Expression Regulation; Genes, fos; In Situ Hybridization; Medulla Oblongata; Neurons; Pentylenetetrazole; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures; Solitary Nucleus; Time Factors | 1994 |
The effects of cocaine-induced seizures on the proenkephalin mRNA level in the mouse hippocampus: a possible involvement of the nitric oxide pathway.
Topics: Animals; Arginine; Cocaine; Enkephalins; Gene Expression; Hippocampus; In Situ Hybridization; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Protein Precursors; RNA, Messenger; Seizures | 1994 |
Area tempestas modulates the behavioural responses to nociceptive stimuli in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anticonvulsants; Azocines; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Escape Reaction; Foot; Hot Temperature; Male; Morphine; Naltrexone; Narcotic Antagonists; Olfactory Pathways; Pain; Phenazocine; Pressure; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Seizures; Tail | 1993 |
Convulsive effects of systemic administration of the delta opioid agonist BW373U86 in mice.
Topics: Amino Acid Sequence; Animals; Anticonvulsants; Benzamides; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Midazolam; Molecular Sequence Data; Naltrexone; Pentylenetetrazole; Piperazines; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures | 1993 |
Acute down-regulation of oxytocin and vasopressin mRNA levels following metrazole-induced seizure in the rat.
Topics: Animals; Blotting, Northern; Cell Nucleus; Enkephalins; Gene Expression; Hypothalamus; Male; Oxytocin; Pentylenetetrazole; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures; Supraoptic Nucleus; Transcription, Genetic; Vasopressins | 1993 |
Early changes in prodynorphin mRNA and ir-dynorphin A levels after kindled seizures in the rat.
Topics: Amygdala; Animals; Blotting, Northern; Dynorphins; Enkephalins; Kindling, Neurologic; Male; Protein Precursors; Radioimmunoassay; Rats; Rats, Sprague-Dawley; RNA Probes; RNA, Messenger; Seizures | 1995 |
Dextromethorphan blocks opioid peptide gene expression in the rat hippocampus induced by kainic acid.
Topics: Animals; Dextromethorphan; Enkephalins; Gene Expression Regulation; Hippocampus; In Situ Hybridization; Kainic Acid; Male; Neurotoxins; Protein Precursors; Rats; Rats, Inbred F344; RNA, Messenger; Seizures; Transcription, Genetic | 1997 |
Enkephalin, PPE mRNA, and PTS-1 in alcohol withdrawal seizure-prone and -resistant mice.
Topics: Animals; Enkephalin, Methionine; Enkephalins; Ethanol; Female; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Protein Precursors; RNA, Messenger; Seizures; Substance Withdrawal Syndrome | 1998 |
Limbic seizures induce neuropeptide and chromogranin mRNA expression in rat adrenal medulla.
Topics: Adrenal Medulla; Animals; Chromogranin A; Chromogranins; Enkephalins; Epinephrine; Gene Expression Regulation; Kainic Acid; Kinetics; Limbic System; Male; Neuropeptide Y; Norepinephrine; Protein Biosynthesis; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures; Thiopental; Transcription, Genetic | 1997 |
Evidence for Fos involvement in the regulation of proenkephalin and prodynorphin gene expression in the rat hippocampus.
Topics: Animals; Enkephalins; Gene Expression Regulation; Genes, fos; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Oligonucleotides, Antisense; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Seizures; Transcriptional Activation | 1998 |
The effect of pentylenetetrazol kindling on synaptic mechanisms of interacting glutamatergic and opioid system in the hippocampus of rats.
Topics: Animals; Convulsants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Opioid; Seizures; Synapses | 1998 |
Withdrawal from alcohol in withdrawal seizure-prone and -resistant mice: evidence for enkephalin resistance.
Topics: Aluminum; Animals; Brain Chemistry; Central Nervous System Depressants; Digoxigenin; Enkephalin, Methionine; Enkephalins; Ethanol; Female; Half-Life; Mice; Mice, Inbred Strains; MSH Release-Inhibiting Hormone; Neuropeptides; Protein Precursors; Radioimmunoassay; RNA, Messenger; Seizures; Substance Withdrawal Syndrome | 2001 |
Different brain areas mediate the analgesic and epileptic properties of enkephalin.
Topics: Analgesia; Animals; Brain; Cerebral Aqueduct; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Male; Naloxone; Rats; Receptors, Opioid; Seizures; Thalamic Nuclei | 1978 |
Epileptic properties of leucine- and methionine-enkephalin: comparison with morphine and reversibility by naloxone.
Topics: Animals; Dose-Response Relationship, Drug; Electroencephalography; Endorphins; Enkephalins; Injections, Intraventricular; Leucine; Male; Methionine; Morphine; Naloxone; Rats; Receptors, Opioid; Seizures | 1978 |
Endogenous opioids may mediate post-ictal behavioral depression in amygdaloid-kindled rats.
Topics: Amygdala; Animals; Behavior, Animal; Electric Stimulation; Electroencephalography; Endorphins; Enkephalins; Evoked Potentials; Morphine; Naloxone; Rats; Receptors, Opioid; Seizures | 1979 |
Effects of opiate-like peptides, morphine, and naloxone in the photosensitive baboon, Papio papio.
Topics: Animals; Blood Pressure; Cerebral Cortex; Electroencephalography; Endorphins; Enkephalins; Evoked Potentials; Haplorhini; Injections, Intramuscular; Injections, Intraventricular; Morphine; Myoclonus; Naloxone; Papio; Photic Stimulation; Receptors, Opioid; Respiration; Seizures; Thalamic Nuclei | 1979 |
beta-Endorphin induces nonconvulsive limbic seizures.
Topics: Animals; Behavior, Animal; Electroencephalography; Endorphins; Enkephalins; Injections, Intraventricular; Limbic System; Morphine; Motor Activity; Naloxone; Rats; Seizures | 1978 |
Naloxone does not antagonize general anesthesia in the rat.
Topics: Anesthesia, Inhalation; Animals; Dose-Response Relationship, Drug; Enkephalins; Halothane; Naloxone; Rats; Seizures; Spirometry | 1978 |
Effects of met5-enkephalin and naloxone on spontaneous seizures in the Mongolian gerbil.
Topics: Animals; Behavior, Animal; Electroencephalography; Endorphins; Enkephalins; Female; Gerbillinae; Male; Naloxone; Seizures | 1978 |
Morphine and enkephalin: analgesic and epileptic properties.
Topics: Action Potentials; Analgesia; Animals; Brain; Cerebral Aqueduct; Electroencephalography; Enkephalins; Injections, Intraventricular; Male; Morphine; Naloxone; Oligopeptides; Rats; Seizures | 1977 |
Limbic seizures increase cyclophilin mRNA levels in rat hippocampus.
Topics: Amino Acid Isomerases; Animals; Carrier Proteins; Electric Stimulation; Enkephalins; Gene Expression; Hippocampus; Male; Peptidylprolyl Isomerase; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; RNA, Messenger; Seizures | 1992 |
Opioid mu-deficient CXBK mouse and the role of mu 1-receptors in electrically induced convulsions.
Topics: Animals; Electroshock; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Morphine; Receptors, Opioid, mu; Seizures | 1992 |
Preproenkephalin promoter "cassette" confers brain expression and synaptic regulation in transgenic mice.
Topics: Afferent Pathways; Animals; Base Sequence; Brain; Chloramphenicol O-Acetyltransferase; DNA; Enkephalins; Gene Expression; Gene Expression Regulation; Haloperidol; Humans; Mice; Mice, Transgenic; Molecular Sequence Data; Oligodeoxyribonucleotides; Pentylenetetrazole; Promoter Regions, Genetic; Protein Precursors; Recombinant Fusion Proteins; RNA; RNA, Messenger; Seizures; Synapses | 1992 |
The prodynorphin system in the rat hippocampus is differentially influenced by kainic acid and pentetrazole.
Topics: Animals; Autoradiography; Enkephalins; Hippocampus; In Situ Hybridization; In Vitro Techniques; Kainic Acid; Male; Pentylenetetrazole; Protein Precursors; Rats; Rats, Wistar; Reference Values; RNA, Messenger; Seizures; Sulfur Radioisotopes | 1992 |
Systemic administration of kainic acid differentially regulates the levels of prodynorphin and proenkephalin mRNA and peptides in the rat hippocampus.
Topics: Amino Acid Isomerases; Animals; Carrier Proteins; Endorphins; Enkephalins; Gene Expression Regulation; Hippocampus; Injections, Subcutaneous; Kainic Acid; Male; Peptidylprolyl Isomerase; Protein Precursors; Rats; Rats, Inbred F344; RNA, Messenger; Seizures | 1991 |
Short- and long-term alterations of gene expression in limbic structures by repeated electroconvulsive-induced seizures.
Topics: Animals; Electroshock; Enkephalin, Methionine; Enkephalins; Gene Expression Regulation; Limbic System; Male; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Seizures; Tyrosine 3-Monooxygenase | 1990 |
The release of alpha-neoendorphin from rat hippocampus following kainic acid-induced seizures.
Topics: Animals; Endorphins; Enkephalins; Hippocampus; Kainic Acid; Male; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Seizures | 1990 |
Selective kappa antagonist properties of nor-binaltorphimine in the rat MES seizure model.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anticonvulsants; Electroshock; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Naltrexone; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Seizures | 1989 |
Differential antagonism of mu agonists by U50,488H in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Female; Male; Muscle Contraction; Muscle, Smooth; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Seizures; Urinary Bladder | 1987 |
Focal hippocampal lesions induce seizures and long-lasting changes in mossy fiber enkephalin and CCK immunoreactivity.
Topics: Afferent Pathways; Animals; Cholecystokinin; Electroencephalography; Enkephalins; Hippocampus; Immunohistochemistry; Male; Mice; Motor Activity; Nerve Fibers; Seizures; Time Factors | 1988 |
Kainic acid alters the metabolism of Met5-enkephalin and the level of dynorphin A in the rat hippocampus.
Topics: Animals; Dynorphins; Enkephalin, Methionine; Enkephalins; Hippocampus; Histocytochemistry; Immunochemistry; Kainic Acid; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred F344; RNA, Messenger; Seizures | 1986 |
Dynorphin A (1-13): in vivo opioid antagonist actions and non-opioid anticonvulsant effects in the rat flurothyl test.
Topics: Animals; Anticonvulsants; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Flurothyl; Male; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Seizures | 1986 |
Seizures induce dramatic and distinctly different changes in enkephalin, dynorphin, and CCK immunoreactivities in mouse hippocampal mossy fibers.
Topics: Animals; Cholecystokinin; Dynorphins; Enkephalins; Hippocampus; Immunochemistry; Kainic Acid; Mice; Nerve Fibers; Seizures | 1988 |
Evidence for mu opioid receptor mediation of enkephalin-induced electroencephalographic seizures.
Topics: Animals; Electroencephalography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Naloxone; Naltrexone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures | 1987 |
Increased enkephalin gene expression in the hippocampus following seizures.
Topics: Animals; Enkephalins; Genes; Hippocampus; Male; Protein Precursors; Rats; Rats, Inbred Strains; Seizures; Transcription, Genetic | 1986 |
Induction of ornithine decarboxylase as a possible mediator of seizure-elicited changes in genomic expression in rat hippocampus.
Topics: Adrenalectomy; Animals; Enkephalins; Hippocampus; Kinetics; Male; Ornithine Decarboxylase; Pentobarbital; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Seizures | 1986 |
Enkephalins: immunomodulators.
Topics: Acoustic Stimulation; Adjuvants, Immunologic; Animals; Enkephalins; Granuloma; Humans; Killer Cells, Natural; Leukemia L1210; Lymphocyte Activation; Mice; Organ Size; Rosette Formation; Seizures; Spleen; Thymus Gland | 1985 |
Cerebrospinal fluid leucine-enkephalin-like levels in febrile convulsions.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Brain Chemistry; Child; Child, Preschool; Enkephalin, Leucine; Enkephalins; Female; Humans; Male; Middle Aged; Narcotics; Seizures; Seizures, Febrile | 1985 |
Hypoxic preconditioning attenuates global cerebral ischemic injury following asphyxial cardiac arrest through regulation of delta opioid receptor system.
Topics: Animals; Apoptosis; Arousal; Asphyxia; Behavior, Animal; Blotting, Western; Brain Ischemia; Brain Stem; Enkephalin, Leucine; Fluorescent Antibody Technique; Heart Arrest; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia, Brain; In Situ Nick-End Labeling; Ischemic Preconditioning; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Postural Balance; Rats; Real-Time Polymerase Chain Reaction; Receptors, Opioid, delta; RNA, Small Interfering; Seizures; Survival Analysis | 2012 |
Mu and delta opioid receptor interactions in a rat model of drug induced seizures.
Topics: Animals; Disease Models, Animal; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures | 1984 |
Seizures induced by carbachol, morphine, and leucine-enkephalin: a comparison.
Topics: Animals; Carbachol; Enkephalin, Leucine; Male; Morphine; Rats; Receptors, Opioid; Seizures | 1983 |
A selective role for delta-receptors in the regulation of opioid-induced changes in seizure threshold.
Topics: Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Male; Meperidine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures; Sensory Thresholds | 1983 |
ICI 154,129, a delta-opioid receptor antagonist raises seizure threshold in rats.
Topics: Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Seizures | 1984 |
Metabolic rate in different rat brain areas during seizures induced by a specific delta opiate receptor agonist.
Topics: Animals; Brain; Carbon Radioisotopes; Deoxy Sugars; Deoxyglucose; Electroencephalography; Enkephalin, Leucine; Kinetics; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures | 1984 |
Opioid antagonism of electroshock-induced seizures.
Topics: Animals; beta-Endorphin; Electroshock; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Mice; Mice, Inbred C57BL; Morphine; Naltrexone; Narcotics; Seizures; Time Factors | 1984 |
The ontogeny of seizures induced by leucine-enkephalin and beta-endorphin.
Topics: Aging; Animals; beta-Endorphin; Brain; Electroencephalography; Endorphins; Enkephalin, Leucine; Evoked Potentials; Male; Naloxone; Rats; Rats, Inbred Strains; Seizures | 1984 |
Correlation between the distribution of 3H-labelled enkephalin in rat brain and the anatomical regions involved in enkephalin-induced seizures.
Topics: Animals; Autoradiography; Brain; Diffusion; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Evoked Potentials; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Seizures | 1983 |
Differential epileptogenic potentials of selective mu and delta opiate receptor agonists.
Topics: Animals; Convulsants; Drug Interactions; Endorphins; Enkephalin, Leucine; Hippocampus; Injections; Injections, Intraventricular; Male; Oligopeptides; Rats; Rats, Inbred Strains; Seizures | 1983 |
Intracerebral opiates block the epileptic effect of intracerebroventricular (ICV) leucine-enkephalin.
Topics: Animals; Anticonvulsants; Drug Interactions; Enkephalin, Leucine; Injections, Intraventricular; Levorphanol; Male; Morphine; Nucleus Accumbens; Periaqueductal Gray; Rats; Rats, Inbred Strains; Seizures | 1983 |
Brain content of immunoreactive [Leu5]enkephalin and [Met5]enkephalin after pentylenetetrazol-induced convulsions.
Topics: Animals; Brain; Enkephalin, Leucine; Enkephalin, Methionine; Male; Pentylenetetrazole; Radioimmunoassay; Rats; Rats, Inbred Strains; Seizures | 1983 |
Opioid peptides content in the rat brain during the ictal phase and after pentylenetetrazol-kindled rats.
Topics: Animals; Brain; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Kindling, Neurologic; Male; Pentylenetetrazole; Radioimmunoassay; Rats; Rats, Wistar; Seizures; Time Factors; Tissue Distribution | 1995 |
[Changes of Leu-enkephalin in striatum and hypothalamus of rats during hyperbaric oxygen exposure].
Topics: Animals; Atmosphere Exposure Chambers; Corpus Striatum; Enkephalin, Leucine; Hyperbaric Oxygenation; Hypothalamus; Male; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Seizures | 1993 |
[The effect of leucine enkephalin on the development of a convulsive afterdischarge in the sensorimotor cortex of rats].
Topics: Animals; Electric Stimulation; Enkephalin, Leucine; Evoked Potentials; Male; Motor Cortex; Neurons; Rats; Reaction Time; Seizures | 1992 |
[Changes in the contents of peptides in the sensory-motor cortex of rats in response to post-stimulation convulsive discharges].
Topics: Animals; Electric Stimulation; Electrophysiology; Enkephalin, Leucine; Enkephalin, Methionine; Male; Motor Cortex; Neuropeptides; Rats; Seizures; Somatosensory Cortex; Somatostatin | 1992 |
Alteration of opioid receptors in seizure-susceptible El mouse brain.
Topics: Animals; Brain; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Kinetics; Mice; Receptors, Opioid; Seizures; Subcellular Fractions | 1989 |
Mu- and delta-opioid modulation of electrically-induced epileptic seizures in mice.
Topics: Animals; Electric Stimulation; Enkephalin, Leucine; Epilepsy; Mice; Morphine; Naloxone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures | 1986 |
Endogenous anticonvulsant substance in rat cerebrospinal fluid after a generalized seizure.
Topics: Animals; Anticonvulsants; Electroshock; Enkephalin, Leucine; Male; Naloxone; Narcotic Antagonists; Peptide Hydrolases; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures | 1985 |
The anticonvulsant effects of DADLE are primarily mediated by activation of delta opioid receptors: interactions between delta and mu receptor antagonists.
Topics: Animals; Anticonvulsants; Cerebral Ventricles; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures | 1985 |
Opiate-induced seizures: a study of mu and delta specific mechanisms.
Topics: Animals; Electroencephalography; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Morphine; Narcotics; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures | 1986 |
Studies on the effects of intrathalamically injected DADL and morphine on nociceptive thresholds and electroencephalographic activity: a thalamic delta receptor syndrome.
Topics: Animals; Electroencephalography; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Morphine; Pain; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures; Sensory Thresholds; Thalamus | 1986 |
Audiogenic seizures during ethanol withdrawal can be blocked by a delta opioid agonist.
Topics: Acoustic Stimulation; Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethanol; Female; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures; Substance Withdrawal Syndrome | 1986 |
Effects of delta opioid antagonists on enkephalin-induced seizures.
Topics: Animals; Enkephalin, Leucine; Male; Narcotic Antagonists; Oligopeptides; Rats; Receptors, Opioid; Seizures | 1987 |