antipyrine has been researched along with Seizures in 20 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To explore the effect of edaravone (ED) on apoptosis of hippocampus neurons in seizures rats induced by pentylenetetrazole (PTZ)." | 7.80 | Effect of edaravone on apoptosis of hippocampus neuron in seizures rats kindled by pentylenetetrazole. ( Cheng, XL; Zhang, JJ, 2014) |
| "To explore the effect of edaravone (ED) on apoptosis of hippocampus neurons in seizures rats induced by pentylenetetrazole (PTZ)." | 3.80 | Effect of edaravone on apoptosis of hippocampus neuron in seizures rats kindled by pentylenetetrazole. ( Cheng, XL; Zhang, JJ, 2014) |
| " Edaravone increased expression of GRP78 and decreased expression of caspase-12 in hippocampus rat with pilocarpine-induced seizures, reduced the number of neuronal apoptosis." | 3.77 | [Effects of edaravone on the expression of GRP78, Caspase-12, and neuron apoptosis in juvenile rat hippocampus after status convulsive]. ( Jiang, CM; Li, GQ; Wang, HP, 2011) |
| "Edaravone inhibited expression of IL-1beta and NF-kappaB in pilocarpine-induced seizures in rat hippocampus, reduced the number of neuronal apoptosis." | 3.75 | [Effects of edaravone on the expression of interleukin-1beta, nuclear factor-kappaB and neuron apoptosis in juvenile rat hippocampus after status convulsion]. ( Deng, XL; Li, GQ; Wang, HP, 2009) |
| " In the rat model of amygdala-kindled seizures, we measured CBF changes with the quantitative [(14)C]-iodoantipyrine autoradiographic method during secondary generalized (SGS, n=26 fully-kindled rats) and focal seizures (FS, n=19 partially kindled rats), according to sequential timing of injection with respect to seizure onset." | 3.74 | [Epileptogenic and non-epileptogenic zones: blood flow studies of temporo-limbic seizures]. ( Armspach, JP; Chassagnon, S; Hirsch, E; Kehrli, P; Namer, IJ; Nehlig, A, 2007) |
| " Local coupling of blood flow and metabolism was studied under different types of anesthesia (barbiturate, halothane), following experimental tumor implantation, and during penicillin seizures or spreading depression." | 3.66 | A double tracer autoradiographic technique for simultaneous measurement of cerebral blood flow and cerebral metabolism in rats. ( Hossmann, KA; Mies, G; Niebuhr, I, 1981) |
| "The kainic acid (KA) model of induced seizures has been widely used to study temporal lobe epilepsy." | 1.40 | 3-Methyl-1-phenyl-2-pyrazolin-5-one or N-acetylcysteine prevents hippocampal mossy fiber sprouting and rectifies subsequent convulsive susceptibility in a rat model of kainic acid-induced seizure ceased by pentobarbital. ( Fukui, M; Miyamoto, R; Nomura, S; Shimakawa, S; Tamai, H, 2014) |
| "The tracer was injected at 30 s before seizure induction (early ictal), simultaneous with the application of stimulation (ictal), at 60 s after stimulation (late ictal), at the end of the electrical afterdischarge (early postictal), and at 6 min after the stimulation (late postictal)." | 1.33 | Time course and mapping of cerebral perfusion during amygdala secondarily generalized seizures. ( Chassagnon, S; de Vasconcelos, AP; Ferrandon, A; Koning, E; Marescaux, C; Nehlig, A, 2005) |
| "During stage 0 seizures, LCBF rates increased significantly ipsilaterally in medial and central amygdala and substantia nigra." | 1.33 | Optimal window for ictal blood flow mapping. Insight from the study of discrete temporo-limbic seizures in rats. ( André, V; Chassagnon, S; Ferrandon, A; Koning, E; Nehlig, A, 2006) |
| "Seizures were induced by topical bicuculline methiodide applied through two cranial windows drilled over homotopic sites of the frontal cortex, and LCBF was measured by quantitative autoradiography by using 4-iodo[N-methyl-14C]antipyrine." | 1.29 | Nitric oxide mediates the increase in local cerebral blood flow during focal seizures. ( Baldwin, RA; Pereira de Vasconcelos, A; Wasterlain, CG, 1995) |
| "Limbic seizure status was induced by microinjection of kainic acid into a unilateral amygdala in rats." | 1.28 | Uncoupling of local blood flow and metabolism in the hippocampal CA3 in kainic acid-induced limbic seizure status. ( Nishihara, I; Sako, K; Tanaka, S; Tanaka, T; Yonemasu, Y, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (35.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 5 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, XL | 1 |
| Zhang, JJ | 1 |
| Nomura, S | 1 |
| Shimakawa, S | 1 |
| Miyamoto, R | 1 |
| Fukui, M | 1 |
| Tamai, H | 1 |
| Baba, A | 1 |
| Kawakami, Y | 1 |
| Saito, K | 1 |
| Murashima, YL | 1 |
| Itoh, Y | 1 |
| Wang, HP | 3 |
| Deng, XL | 2 |
| Li, GQ | 3 |
| Jiang, CM | 1 |
| André, V | 2 |
| Henry, D | 1 |
| Nehlig, A | 4 |
| ZAKHARIIA, EA | 1 |
| ZAPADNIUK, VI | 1 |
| TOPCHIBASHEV, IM | 1 |
| ISAKHANOV, AG | 1 |
| Chassagnon, S | 3 |
| de Vasconcelos, AP | 1 |
| Ferrandon, A | 2 |
| Koning, E | 2 |
| Marescaux, C | 1 |
| Armspach, JP | 1 |
| Namer, IJ | 1 |
| Kehrli, P | 1 |
| Hirsch, E | 1 |
| Büch, HP | 1 |
| Baldauf, J | 1 |
| Wolff, I | 1 |
| Mies, G | 1 |
| Niebuhr, I | 1 |
| Hossmann, KA | 1 |
| Pereira de Vasconcelos, A | 1 |
| Baldwin, RA | 1 |
| Wasterlain, CG | 1 |
| Ueno, H | 1 |
| Yamashita, Y | 1 |
| Caveness, WF | 1 |
| Shih, TM | 1 |
| Scremin, OU | 1 |
| Tanaka, S | 1 |
| Sako, K | 1 |
| Tanaka, T | 1 |
| Nishihara, I | 1 |
| Yonemasu, Y | 1 |
| Rimmer, EM | 1 |
| Richens, A | 1 |
| Dupont, V | 1 |
| Vachon, F | 1 |
| Emile, J | 1 |
| Carbon, C | 1 |
20 other studies available for antipyrine and Seizures
| Article | Year |
|---|---|
Effect of edaravone on apoptosis of hippocampus neuron in seizures rats kindled by pentylenetetrazole.
Topics: Animals; Antipyrine; Apoptosis; Caspase 3; Edaravone; fas Receptor; Hippocampus; Kindling, Neurologi | 2014 |
3-Methyl-1-phenyl-2-pyrazolin-5-one or N-acetylcysteine prevents hippocampal mossy fiber sprouting and rectifies subsequent convulsive susceptibility in a rat model of kainic acid-induced seizure ceased by pentobarbital.
Topics: Acetylcysteine; Aldehydes; Animals; Anticonvulsants; Antipyrine; Cell Survival; Edaravone; Excitator | 2014 |
Effects of Edaravone on Hippocampal Antioxidants in EL Mice.
Topics: Action Potentials; Animals; Antioxidants; Antipyrine; Edaravone; Electroencephalography; Glutathione | 2016 |
[Effects of edaravone on the expression of interleukin-1beta, nuclear factor-kappaB and neuron apoptosis in juvenile rat hippocampus after status convulsion].
Topics: Animals; Antipyrine; Apoptosis; Edaravone; Hippocampus; Interleukin-1beta; Male; Neurons; NF-kappa B | 2009 |
[Effects of edaravone on glial fibrillary acidic protein and interleukin-lβ expression and neuronal apoptosis in juvenile rat hippocampus after status convulsion].
Topics: Animals; Antipyrine; Apoptosis; Edaravone; Free Radical Scavengers; Glial Fibrillary Acidic Protein; | 2011 |
[Effects of edaravone on the expression of GRP78, Caspase-12, and neuron apoptosis in juvenile rat hippocampus after status convulsive].
Topics: Animals; Antipyrine; Apoptosis; Caspase 12; Edaravone; Heat-Shock Proteins; Hippocampus; Male; Rats; | 2011 |
Dynamic variations of local cerebral blood flow in maximal electroshock seizures in the rat.
Topics: Animals; Antipyrine; Autoradiography; Brain; Carbon Radioisotopes; Cerebral Cortex; Electroshock; Hy | 2002 |
[THE REPRODUCTION OF AUDIOGENIC CONVULSIONS AFTER THE PRELIMINARY ADMINISTRATION OF PYRAMIDONE TO ANIMALS].
Topics: Acetazolamide; Aminopyrine; Anticonvulsants; Antipyrine; Epilepsy, Reflex; Mice; Pharmacology; Pheno | 1964 |
[Control of convulsions in tetanus with analgesin].
Topics: Antipyrine; Drug Combinations; Ether; Humans; Plant Oils; Procaine; Seizures; Tetanus; Tetanus Toxoi | 1951 |
Time course and mapping of cerebral perfusion during amygdala secondarily generalized seizures.
Topics: Amygdala; Animals; Antipyrine; Autoradiography; Brain; Brain Mapping; Carbon Radioisotopes; Cerebral | 2005 |
Optimal window for ictal blood flow mapping. Insight from the study of discrete temporo-limbic seizures in rats.
Topics: Amygdala; Animals; Antipyrine; Carbon Radioisotopes; Cerebrovascular Circulation; Electric Stimulati | 2006 |
[Epileptogenic and non-epileptogenic zones: blood flow studies of temporo-limbic seizures].
Topics: Animals; Antipyrine; Cerebrovascular Circulation; Electroencephalography; Epilepsy, Temporal Lobe; F | 2007 |
[Drug distribution during convulsive seizure in comparison with narcosis].
Topics: Adipose Tissue; Animals; Antipyrine; Brain; Female; Liver; Pentylenetetrazole; Phenobarbital; Rats; | 1980 |
A double tracer autoradiographic technique for simultaneous measurement of cerebral blood flow and cerebral metabolism in rats.
Topics: Animals; Antipyrine; Autoradiography; Brain; Brain Neoplasms; Cerebrovascular Circulation; Cortical | 1981 |
Nitric oxide mediates the increase in local cerebral blood flow during focal seizures.
Topics: Amino Acid Oxidoreductases; Animals; Antipyrine; Arginine; Autoradiography; Bicuculline; Cerebrovasc | 1995 |
Regional cerebral blood flow pattern in focal epileptiform seizures in the monkey.
Topics: Animals; Antipyrine; Carbon Radioisotopes; Caudate Nucleus; Cerebellum; Cerebral Cortex; Cerebrovasc | 1975 |
Cerebral blood flow and metabolism in soman-induced convulsions.
Topics: Animals; Antipyrine; Autoradiography; Behavior, Animal; Blood Pressure; Brain Chemistry; Cerebrovasc | 1992 |
Uncoupling of local blood flow and metabolism in the hippocampal CA3 in kainic acid-induced limbic seizure status.
Topics: Animals; Antipyrine; Autoradiography; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; D | 1990 |
Interaction between vigabatrin and phenytoin.
Topics: Adolescent; Adult; Aminocaproates; Anticonvulsants; Antipyrine; Blood Proteins; Drug Interactions; F | 1989 |
[Cerebral malaria with deep coma and acute renal insufficiency. Cure after 6 days of respiratory resuscitation associated with specific treatment of the malaria].
Topics: Acute Kidney Injury; Antipyrine; Brain Diseases; Coma; Humans; Malaria; Male; Middle Aged; Neurologi | 1967 |