oxolinic acid has been researched along with Seizures in 2 studies
quinolone antibiotic : An organonitrogen heterocyclic antibiotic whose structure contains a quinolone or quinolone-related skeleton.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mice were observed for convulsions for 90 minutes after the administration of temafloxacin HCl (100 mg/kg orally [p." | 1.28 | Assessment of temafloxacin neurotoxicity in rodents. ( Giardina, WJ, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giardina, WJ | 1 |
| Williams, PD | 1 |
| Helton, DR | 1 |
2 other studies available for oxolinic acid and Seizures
| Article | Year |
|---|---|
Assessment of temafloxacin neurotoxicity in rodents.
Topics: Animals; Anti-Infective Agents; Central Nervous System; Ciprofloxacin; Enoxacin; Fluoroquinolones; M | 1991 |
The proconvulsive activity of quinolone antibiotics in an animal model.
Topics: Animals; Anti-Infective Agents; Convulsants; Dose-Response Relationship, Drug; Male; Mice; Mice, Inb | 1991 |