citalopram has been researched along with Seizures in 49 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We tested the hypothesis that escitalopram (the therapeutically active S-enantiomer of citalopram) causes fewer seizures in overdose than citalopram at comparable doses of the S-enantiomer." | 7.76 | Escitalopram causes fewer seizures in human overdose than citalopram. ( Bauer, K; Ceschi, A; Gerber-Zupan, G; Hackl, E; Hoffmann-Walbeck, P; Kullak-Ublick, GA; Kupferschmidt, H; Prasa, D; Rauber-Lüthy, C; Sauer, O; Seidel, C; Stedtler, U; Wilks, M; Yilmaz, Z, 2010) |
| " Citalopram, a newer generation SSRI, is commonly prescribed, but despite its low toxicity profile has a potential to cause seizures and dysarrythmias in overdose." | 7.76 | Metabolic acidosis and generalized seizures secondary to citalopram overdose: a case report. ( Al Anazi, T; Al Hayyan, H; Al Hussein, M; Al Modaimegh, H; Al Qahtani, M; Bin Salih, S, 2010) |
| "Generalized seizures are an important manifestation of citalopram toxicity, and cannot be explained solely by electrolyte disturbances or co-ingestion of other drugs or ethanol." | 7.74 | Predictive factors for generalized seizures after deliberate citalopram overdose. ( Graham, A; Gray, JA; Waring, WS, 2008) |
| " In the present study we performed parallel measurements of BDNF mRNA and protein expression in the frontal cortex and hippocampus of the rat after chronic treatment with electroconvulsive seizures (ECS), lithium, desipramine or escitalopram." | 7.72 | The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels. ( Jacobsen, JP; Mørk, A, 2004) |
| "In this regard, we used a model of clonic seizures induced by pentylenetetrazole (PTZ) in male NMRI mice to investigate whether morphine and citalopram exhibit additive anticonvulsant effects and, if so, whether this effect is mediated through modulation of 5-HT(3) receptors." | 5.37 | The role of 5-HT(3) receptors in the additive anticonvulsant effects of citalopram and morphine on pentylenetetrazole-induced clonic seizures in mice. ( Bahremand, A; Dehpour, AR; Ebrahimi, A; Fakhfouri, G; Ghasemi, A; Ghasemi, M; Loloee, S; Payandemehr, B; Pourmand, N; Rahimian, R; Ziai, P, 2011) |
| " Initially, dose-response experiments were performed with intrahippocampal perfusions of GBR-12909 and citalopram, respectively, selective dopamine and serotonin re-uptake blockers." | 5.32 | Anticonvulsant action of GBR-12909 and citalopram against acute experimentally induced limbic seizures. ( Clinckers, R; Ebinger, G; Meurs, A; Michotte, Y; Smolders, I, 2004) |
| "Citalopram was discontinued and fluid restriction was instituted." | 5.32 | Severe symptomatic hyponatremia during citalopram therapy--a case report. ( Cobos-Ayala, C; Flores, G; Perez-Patrigeon, S; Vergara, J, 2004) |
| " In a study with a double-blind, cross-over design, the authors evaluated the effect of citalopram, the most selective SSRI available, on the length of electrically induced seizures and on hormone secretion during ECT." | 5.09 | Administration of citalopram before ECT: seizure duration and hormone responses. ( Daras, M; Markianos, M; Papakostas, YG; Theodoropoulou, M; Vaidakis, N; Zervas, IM, 2000) |
| "Antidepressants were frequently associated with seizures in overdose, but other pharmaceuticals, as mefenamic acid, were also associated with seizures in a considerable number of cases." | 3.80 | Seizures after single-agent overdose with pharmaceutical drugs: analysis of cases reported to a poison center. ( Ceschi, A; Kupferschmidt, H; Monnet-Tschudi, F; Rauber-Lüthy, C; Reichert, C; Reichert, P, 2014) |
| "This is a case of a citalopram and olanzapine overdose causing seizures and severe cardiotoxicity." | 3.79 | Cardiotoxicity in a citalopram and olanzapine overdose. ( Gerona, RR; Lung, DD; Wu, AH, 2013) |
| " Citalopram significantly decreased the spontaneous seizure frequency at the highest dose tested, that is, the mean number of seizures decreased from 12." | 3.78 | The antidepressants citalopram and reboxetine reduce seizure frequency in rats with chronic epilepsy. ( Clinckers, R; Massie, A; Smolders, I; Vermoesen, K, 2012) |
| " Seizures and ECG changes, while uncommon, occur more frequently with citalopram." | 3.78 | Comparison of citalopram and other selective serotonin reuptake inhibitor ingestions in children. ( Benson, BE; Klein-Schwartz, W; Lee, SC; Litovitz, T, 2012) |
| "Escitalopram seems to be less toxic than citalopram after an acute overdose; seizures and tremors were more common with citalopram." | 3.76 | Comparison of toxicity of acute overdoses with citalopram and escitalopram. ( Clark, RF; Hayes, BD; Klein-Schwartz, W; Miloradovich, JE; Muller, AA, 2010) |
| " Citalopram, a newer generation SSRI, is commonly prescribed, but despite its low toxicity profile has a potential to cause seizures and dysarrythmias in overdose." | 3.76 | Metabolic acidosis and generalized seizures secondary to citalopram overdose: a case report. ( Al Anazi, T; Al Hayyan, H; Al Hussein, M; Al Modaimegh, H; Al Qahtani, M; Bin Salih, S, 2010) |
| "We tested the hypothesis that escitalopram (the therapeutically active S-enantiomer of citalopram) causes fewer seizures in overdose than citalopram at comparable doses of the S-enantiomer." | 3.76 | Escitalopram causes fewer seizures in human overdose than citalopram. ( Bauer, K; Ceschi, A; Gerber-Zupan, G; Hackl, E; Hoffmann-Walbeck, P; Kullak-Ublick, GA; Kupferschmidt, H; Prasa, D; Rauber-Lüthy, C; Sauer, O; Seidel, C; Stedtler, U; Wilks, M; Yilmaz, Z, 2010) |
| "Generalized seizures are an important manifestation of citalopram toxicity, and cannot be explained solely by electrolyte disturbances or co-ingestion of other drugs or ethanol." | 3.74 | Predictive factors for generalized seizures after deliberate citalopram overdose. ( Graham, A; Gray, JA; Waring, WS, 2008) |
| "We report a case of citalopram poisoning in a 10-month-old infant with refractory seizures, and an absence of cardiovascular events with subsequent excellent outcome." | 3.73 | Clinical course and toxicokinetic data following isolated citalopram overdose in an infant. ( Baker, SD; Bose, S; Levsky, M; Masullo, LN; Miller, MA, 2006) |
| "The involvement of chronic inhibition of monoamine transporters (MAT) in the brain with respect to sensitization to cocaine- and local anesthetic-induced seizures was studied in mice." | 3.72 | Chronic inhibition of the norepinephrine transporter in the brain participates in seizure sensitization to cocaine and local anesthetics. ( Arai, S; Dohi, T; Kihira, K; Kitayama, S; Kumagai, K; Kumagai, M; Morita, K, 2003) |
| " In the present study we performed parallel measurements of BDNF mRNA and protein expression in the frontal cortex and hippocampus of the rat after chronic treatment with electroconvulsive seizures (ECS), lithium, desipramine or escitalopram." | 3.72 | The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels. ( Jacobsen, JP; Mørk, A, 2004) |
| "Nisoxetine and desipramine (inhibitors of norepinephrine reuptake) each exerted a suppressant effect on spinal cord seizures by decreasing the duration of tonic extension." | 3.66 | Effects of norepinephrine and 5-hydroxytryptamine reuptake inhibitors on electrically-induced spinal cord seizures in rats. ( Jobe, PC; Ray, TB, 1980) |
| "5-HT modulates seizure susceptibility and severity and is dysregulated by seizures." | 1.91 | Selective Serotonin Reuptake Inhibitors and 5-HT ( Boodhoo, NA; Buchanan, GF; Joyal, KG; Littlepage-Saunders, MV; Petrucci, AN; Wendt, LH, 2023) |
| "No cardiac rhythm disturbances or convulsions were seen." | 1.56 | Citalopram intoxication in four week old infant. ( Eijkemans, M; Janson, JA; Kerskes, M; Wasylewicz, ATM, 2020) |
| "The risk of seizure during therapeutic use among elderly patients varies among second-generation anti-depressants." | 1.48 | Second-generation anti-depressants and risk of new-onset seizures in the elderly. ( Finkelstein, Y; Gomes, T; Juurlink, DN; Li, P; Macdonald, EM; Mamdani, MM, 2018) |
| "Mixed connective tissue disorder (MCTD) with predominant polymyositis and neuropsychiatric manifestations was diagnosed as the patient had anti-RNP positive with significantly raised muscle enzymes." | 1.40 | Depression and seizures as the main neuropsychiatric manifestation of mixed connective tissue disorder. ( Kiani, IG; Qureshi, SH; Shah, F, 2014) |
| "Citalopram is a selective serotonin reuptake inhibitor (SSRI), widely used in the treatment of depressive disorders." | 1.38 | 5-HT(3) receptor mediates the dose-dependent effects of citalopram on pentylenetetrazole-induced clonic seizure in mice: involvement of nitric oxide. ( Amouzegar, A; Bahremand, A; Dehpour, AR; Payandemehr, B; Rahimian, R; Sharifzadeh, M; Ziai, P, 2012) |
| "However, serotonin syndrome, seizures, electrocardiographic abnormalities as well as respiratory failure and death have been described in patients with citalopram overdose." | 1.38 | Mechanisms of high-dose citalopram-induced death in a rat model. ( Baud, FJ; Beaune, S; Callebert, J; Juvin, P; Mégarbane, B; Risède, P, 2012) |
| "In this regard, we used a model of clonic seizures induced by pentylenetetrazole (PTZ) in male NMRI mice to investigate whether morphine and citalopram exhibit additive anticonvulsant effects and, if so, whether this effect is mediated through modulation of 5-HT(3) receptors." | 1.37 | The role of 5-HT(3) receptors in the additive anticonvulsant effects of citalopram and morphine on pentylenetetrazole-induced clonic seizures in mice. ( Bahremand, A; Dehpour, AR; Ebrahimi, A; Fakhfouri, G; Ghasemi, A; Ghasemi, M; Loloee, S; Payandemehr, B; Pourmand, N; Rahimian, R; Ziai, P, 2011) |
| "Escitalopram (ESC) is a novel selective serotonin reuptake inhibitor that seems to have a favorable side effect profile." | 1.35 | The safety of the electroconvulsive therapy-escitalopram combination. ( Florakis, A; Markatou, M; Masdrakis, VG; Oulis, P; Papadimitriou, GN; Valamoutopoulos, T, 2008) |
| "We used assessment of seizure severity in the focal pilocarpine model, antidepressant-like activity within the rat forced swim and the mouse tail suspension tests, and locomotor activity in an open field as behavioural tests." | 1.35 | Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant-anticonvulsant action. ( Clinckers, R; De Bundel, D; Ebinger, G; Meurs, A; Michotte, Y; Portelli, J; Smolders, I, 2008) |
| "Citalopram was discontinued and fluid restriction was instituted." | 1.32 | Severe symptomatic hyponatremia during citalopram therapy--a case report. ( Cobos-Ayala, C; Flores, G; Perez-Patrigeon, S; Vergara, J, 2004) |
| "The seizure was successfully treated with benzodiazepines." | 1.32 | Seizure secondary to citalopram overdose. ( Cuenca, PJ; Hoefle, JD; Holt, KR, 2004) |
| "Differentiation of pseudoseizures from epileptic seizures and hysterical stridor from asthma is key to the treatment of patients." | 1.32 | Pseudoseizures and hysterical stridor. ( Kaufman, KR; Mohebati, A; Sotolongo, A, 2004) |
| " Initially, dose-response experiments were performed with intrahippocampal perfusions of GBR-12909 and citalopram, respectively, selective dopamine and serotonin re-uptake blockers." | 1.32 | Anticonvulsant action of GBR-12909 and citalopram against acute experimentally induced limbic seizures. ( Clinckers, R; Ebinger, G; Meurs, A; Michotte, Y; Smolders, I, 2004) |
| "El mouse convulsions were inhibited by oral administration of citalopram for 2 weeks." | 1.29 | The anticonvulsant effect of citalopram on El mice, and the levels of tryptophan and tyrosine and their metabolites in the brain. ( Kabuto, H; Kurimoto, T; Mori, A; Takei, M; Yokoi, I, 1994) |
| " In the present study we determined the time-course and dose-response effects of 6-MeO-THbetaC for blockade of AGS." | 1.26 | Effects of 6-methoxy-1,2,3,4-tetrahydro-beta-carboline (6-MeO-THbetaC) on audiogenic seizures in DBA/2J mice. ( Buckholtz, NS; Sparks, DL, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (6.12) | 18.7374 |
| 1990's | 6 (12.24) | 18.2507 |
| 2000's | 18 (36.73) | 29.6817 |
| 2010's | 19 (38.78) | 24.3611 |
| 2020's | 3 (6.12) | 2.80 |
| Authors | Studies |
|---|---|
| Joyal, KG | 1 |
| Petrucci, AN | 1 |
| Littlepage-Saunders, MV | 1 |
| Boodhoo, NA | 1 |
| Wendt, LH | 1 |
| Buchanan, GF | 2 |
| Janson, JA | 1 |
| Wasylewicz, ATM | 1 |
| Eijkemans, M | 1 |
| Kerskes, M | 1 |
| Herr, J | 1 |
| Hatch, L | 1 |
| Sephien, A | 1 |
| Hanna, K | 1 |
| Russell, JL | 1 |
| Spiller, HA | 1 |
| Chounthirath, T | 1 |
| Casavant, MJ | 1 |
| Finkelstein, Y | 1 |
| Macdonald, EM | 1 |
| Li, P | 1 |
| Mamdani, MM | 1 |
| Gomes, T | 1 |
| Juurlink, DN | 1 |
| Kruse, SW | 1 |
| Dayton, KG | 1 |
| Purnell, BS | 1 |
| Rosner, JI | 1 |
| Lung, DD | 1 |
| Wu, AH | 1 |
| Gerona, RR | 1 |
| Reichert, C | 1 |
| Reichert, P | 1 |
| Monnet-Tschudi, F | 1 |
| Kupferschmidt, H | 2 |
| Ceschi, A | 2 |
| Rauber-Lüthy, C | 2 |
| Kiani, IG | 1 |
| Qureshi, SH | 1 |
| Shah, F | 1 |
| Pardo-Peña, K | 1 |
| Medina-Ceja, L | 1 |
| Morales-Villagrán, A | 1 |
| Armitage, MC | 1 |
| Woolfield, KI | 1 |
| Page, CB | 1 |
| Abouchedid, R | 1 |
| Ho, JH | 1 |
| Hudson, S | 1 |
| Dines, A | 1 |
| Archer, JR | 1 |
| Wood, DM | 1 |
| Dargan, PI | 1 |
| Masdrakis, VG | 1 |
| Oulis, P | 1 |
| Florakis, A | 1 |
| Valamoutopoulos, T | 1 |
| Markatou, M | 1 |
| Papadimitriou, GN | 1 |
| Waring, WS | 1 |
| Gray, JA | 1 |
| Graham, A | 1 |
| Hayes, BD | 1 |
| Klein-Schwartz, W | 2 |
| Clark, RF | 1 |
| Muller, AA | 1 |
| Miloradovich, JE | 1 |
| Arora, M | 1 |
| Praharaj, SK | 1 |
| Sinha, VK | 1 |
| Sarkar, S | 1 |
| Yilmaz, Z | 1 |
| Sauer, O | 1 |
| Stedtler, U | 1 |
| Prasa, D | 1 |
| Seidel, C | 1 |
| Hackl, E | 1 |
| Hoffmann-Walbeck, P | 1 |
| Gerber-Zupan, G | 1 |
| Bauer, K | 1 |
| Kullak-Ublick, GA | 1 |
| Wilks, M | 1 |
| Bin Salih, S | 1 |
| Al Qahtani, M | 1 |
| Al Anazi, T | 1 |
| Al Hussein, M | 1 |
| Al Hayyan, H | 1 |
| Al Modaimegh, H | 1 |
| Bahremand, A | 2 |
| Payandemehr, B | 2 |
| Rahimian, R | 2 |
| Ziai, P | 2 |
| Pourmand, N | 1 |
| Loloee, S | 1 |
| Ebrahimi, A | 1 |
| Ghasemi, A | 1 |
| Fakhfouri, G | 1 |
| Ghasemi, M | 1 |
| Dehpour, AR | 2 |
| Jaako, K | 1 |
| Aonurm-Helm, A | 1 |
| Kalda, A | 1 |
| Anier, K | 1 |
| Zharkovsky, T | 1 |
| Shastin, D | 1 |
| Zharkovsky, A | 1 |
| Vermoesen, K | 1 |
| Massie, A | 1 |
| Smolders, I | 3 |
| Clinckers, R | 3 |
| Benson, BE | 1 |
| Lee, SC | 1 |
| Litovitz, T | 1 |
| Amouzegar, A | 1 |
| Sharifzadeh, M | 1 |
| Beaune, S | 1 |
| Callebert, J | 1 |
| Baud, FJ | 1 |
| Risède, P | 1 |
| Juvin, P | 1 |
| Mégarbane, B | 1 |
| Szyndler, J | 1 |
| Wierzba-Bobrowicz, T | 1 |
| Maciejak, P | 1 |
| Siemiatkowski, M | 1 |
| Rok, P | 1 |
| Lehner, M | 1 |
| Czlonkowska, AI | 1 |
| Bidzinski, A | 1 |
| Wislowska, A | 1 |
| Zienowicz, M | 1 |
| Plaznik, A | 1 |
| Fisher, A | 1 |
| Davis, M | 1 |
| Croft-Baker, J | 1 |
| Purcell, P | 1 |
| McLean, A | 1 |
| Arai, S | 1 |
| Morita, K | 1 |
| Kitayama, S | 1 |
| Kumagai, K | 1 |
| Kumagai, M | 1 |
| Kihira, K | 1 |
| Dohi, T | 1 |
| Engebretsen, KM | 1 |
| Harris, CR | 1 |
| Wood, JE | 1 |
| Flores, G | 1 |
| Perez-Patrigeon, S | 1 |
| Cobos-Ayala, C | 1 |
| Vergara, J | 1 |
| Cuenca, PJ | 1 |
| Holt, KR | 1 |
| Hoefle, JD | 1 |
| Kaufman, KR | 1 |
| Mohebati, A | 1 |
| Sotolongo, A | 1 |
| Jacobsen, JP | 1 |
| Mørk, A | 2 |
| Meurs, A | 2 |
| Ebinger, G | 2 |
| Michotte, Y | 2 |
| Masullo, LN | 1 |
| Miller, MA | 1 |
| Baker, SD | 1 |
| Bose, S | 1 |
| Levsky, M | 1 |
| Sağlam, E | 1 |
| Kayir, H | 1 |
| Celik, T | 1 |
| Uzbay, T | 1 |
| Solberg, DK | 1 |
| Koht, J | 1 |
| Refsum, H | 1 |
| De Bundel, D | 1 |
| Portelli, J | 1 |
| Rudorfer, MV | 1 |
| Golden, RN | 1 |
| Potter, WZ | 1 |
| Sparks, DL | 1 |
| Buckholtz, NS | 1 |
| Jobe, PC | 1 |
| Ray, TB | 1 |
| Kabuto, H | 1 |
| Yokoi, I | 1 |
| Takei, M | 1 |
| Kurimoto, T | 1 |
| Mori, A | 1 |
| Personne, M | 2 |
| Sjöberg, G | 2 |
| Persson, H | 2 |
| Grundemar, L | 1 |
| Wohlfart, B | 1 |
| Lagerstedt, C | 1 |
| Bengtsson, F | 1 |
| Eklundh, G | 1 |
| Glassman, AH | 1 |
| Papakostas, YG | 1 |
| Markianos, M | 1 |
| Zervas, IM | 1 |
| Theodoropoulou, M | 1 |
| Vaidakis, N | 1 |
| Daras, M | 1 |
| Jensen, JB | 1 |
| Mikkelsen, JD | 1 |
| Maj, J | 1 |
| Rogóz, Z | 1 |
| Skuza, G | 1 |
| Sowińska, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Toxicological Screening by GC-MS Among Children Admitted for a First Afebrile Seizure (CASTox): a Pilot Study[NCT03310697] | 48 participants (Actual) | Interventional | 2017-12-19 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for citalopram and Seizures
| Article | Year |
|---|---|
Citalopram-induced severe hyponatraemia with coma and seizure. Case report with literature and spontaneous reports review.
Topics: Adult; Aged; Aged, 80 and over; Citalopram; Coma; Female; Humans; Hyponatremia; Male; Middle Aged; S | 2002 |
Second-generation antidepressants.
Topics: Alprazolam; Amoxapine; Antidepressive Agents; Benzodiazepines; Bupropion; Citalopram; Clinical Trial | 1984 |
2 trials available for citalopram and Seizures
| Article | Year |
|---|---|
Second-generation antidepressants.
Topics: Alprazolam; Amoxapine; Antidepressive Agents; Benzodiazepines; Bupropion; Citalopram; Clinical Trial | 1984 |
Administration of citalopram before ECT: seizure duration and hormone responses.
Topics: Administration, Oral; Aged; Aged, 80 and over; Citalopram; Cross-Over Studies; Depressive Disorder; | 2000 |
46 other studies available for citalopram and Seizures
| Article | Year |
|---|---|
Selective Serotonin Reuptake Inhibitors and 5-HT
Topics: Animals; Citalopram; Death, Sudden; Mice; Respiration; Seizures; Selective Serotonin Reuptake Inhibi | 2023 |
Citalopram intoxication in four week old infant.
Topics: Child; Citalopram; Gastroesophageal Reflux; Humans; Infant; Seizures; Substance-Related Disorders | 2020 |
27-year-old woman • postpartum seizures • PTSD • history of depression • Dx?
Topics: Adult; Antidepressive Agents; Bupropion; Citalopram; Depression, Postpartum; Female; Humans; Seizure | 2021 |
Pediatric ingestion of vilazodone compared to other selective serotonin reuptake inhibitor medications.
Topics: Child; Child, Preschool; Citalopram; Coma; Dose-Response Relationship, Drug; Evidence-Based Medicine | 2017 |
Second-generation anti-depressants and risk of new-onset seizures in the elderly.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Bupropion; Case-Control Studies; | 2018 |
Effect of monoamine reuptake inhibition and α
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochl | 2019 |
Cardiotoxicity in a citalopram and olanzapine overdose.
Topics: Adult; Benzodiazepines; Bradycardia; Citalopram; Drug Overdose; Electrocardiography; Humans; Hypoten | 2013 |
Seizures after single-agent overdose with pharmaceutical drugs: analysis of cases reported to a poison center.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antidepressive Agents; Child; Child, Presch | 2014 |
Depression and seizures as the main neuropsychiatric manifestation of mixed connective tissue disorder.
Topics: Adult; Antibodies, Antinuclear; Anticonvulsants; Antidepressive Agents, Second-Generation; Azathiopr | 2014 |
Serotonin modulates fast ripple activity in rats with spontaneous recurrent seizures.
Topics: Animals; Catheters, Indwelling; Citalopram; Disease Models, Animal; Electrodes, Implanted; Electroen | 2014 |
Serotonin toxicity caused by the interaction of fentanyl and serotonergic medications.
Topics: Amitriptyline; Anesthetics, Intravenous; Antidepressive Agents, Tricyclic; Citalopram; Drug Interact | 2016 |
Citalopram, escitalopram: no more effective than other SSRIs, but more toxic.
Topics: Citalopram; Depressive Disorder; Humans; Long QT Syndrome; Seizures; Selective Serotonin Reuptake In | 2016 |
Acute Toxicity Associated with Use of 5F-Derivations of Synthetic Cannabinoid Receptor Agonists with Analytical Confirmation.
Topics: Adamantane; Administration, Intravenous; Anti-Anxiety Agents; Cannabinoid Receptor Agonists; Citalop | 2016 |
The safety of the electroconvulsive therapy-escitalopram combination.
Topics: Aged; Bipolar Disorder; Citalopram; Combined Modality Therapy; Depressive Disorder, Major; Electroco | 2008 |
Predictive factors for generalized seizures after deliberate citalopram overdose.
Topics: Adult; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Drug Interactions; Drug Overdose | 2008 |
Comparison of toxicity of acute overdoses with citalopram and escitalopram.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Citalopram; Drug Overdose; Fema | 2010 |
Schizencephaly associated with bipolar II disorder.
Topics: Bipolar Disorder; Brain; Citalopram; Depression; Diagnosis, Differential; Dibenzothiazepines; Humans | 2009 |
Escitalopram causes fewer seizures in human overdose than citalopram.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Austria; Citalopram; Drug Overdose; Female; Germany; Hum | 2010 |
Metabolic acidosis and generalized seizures secondary to citalopram overdose: a case report.
Topics: Acidosis; Anticonvulsants; Citalopram; Depression; Drug Overdose; Female; Humans; Lorazepam; Seizure | 2010 |
The role of 5-HT(3) receptors in the additive anticonvulsant effects of citalopram and morphine on pentylenetetrazole-induced clonic seizures in mice.
Topics: Analysis of Variance; Animals; Anticonvulsants; Biguanides; Citalopram; Disease Models, Animal; Dose | 2011 |
Repeated citalopram administration counteracts kainic acid-induced spreading of PSA-NCAM-immunoreactive cells and loss of reelin in the adult mouse hippocampus.
Topics: Animals; Cell Adhesion Molecules, Neuronal; Cell Count; Citalopram; Down-Regulation; Extracellular M | 2011 |
The antidepressants citalopram and reboxetine reduce seizure frequency in rats with chronic epilepsy.
Topics: Animals; Antidepressive Agents; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug | 2012 |
Comparison of citalopram and other selective serotonin reuptake inhibitor ingestions in children.
Topics: Age Factors; Child, Preschool; Citalopram; Dose-Response Relationship, Drug; Electrocardiography; Fe | 2012 |
5-HT(3) receptor mediates the dose-dependent effects of citalopram on pentylenetetrazole-induced clonic seizure in mice: involvement of nitric oxide.
Topics: Animals; Anticonvulsants; Biguanides; Citalopram; Dose-Response Relationship, Drug; Enzyme Inhibitor | 2012 |
Mechanisms of high-dose citalopram-induced death in a rat model.
Topics: Animals; Body Temperature; Citalopram; Cyproheptadine; Diazepam; Dose-Response Relationship, Drug; L | 2012 |
Pentylenetetrazol-kindling of seizures selectively decreases [3H]-citalopram binding in the CA-3 area of rat hippocampus.
Topics: Animals; Autoradiography; Carrier Proteins; Citalopram; Convulsants; Hippocampus; Immunohistochemist | 2002 |
Chronic inhibition of the norepinephrine transporter in the brain participates in seizure sensitization to cocaine and local anesthetics.
Topics: Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Brain; Brain Chemistry; Citalopram; Cocai | 2003 |
Cardiotoxicity and late onset seizures with citalopram overdose.
Topics: Adult; Citalopram; Drug Overdose; Electrocardiography; Humans; Male; Seizures; Selective Serotonin R | 2003 |
Severe symptomatic hyponatremia during citalopram therapy--a case report.
Topics: Citalopram; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middle Aged; Seizures; Selective | 2004 |
Seizure secondary to citalopram overdose.
Topics: Adenosine; Adult; Anti-Arrhythmia Agents; Anticonvulsants; Antidepressive Agents, Second-Generation; | 2004 |
Pseudoseizures and hysterical stridor.
Topics: Academic Medical Centers; Adult; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents, Second | 2004 |
The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Citalopram; Desipramine; Electroshock; Gene Expre | 2004 |
Anticonvulsant action of GBR-12909 and citalopram against acute experimentally induced limbic seizures.
Topics: Acute Disease; Animals; Anticonvulsants; Biogenic Monoamines; Citalopram; Dopamine; Dopamine Antagon | 2004 |
Clinical course and toxicokinetic data following isolated citalopram overdose in an infant.
Topics: Charcoal; Citalopram; Drug Overdose; Female; Humans; Hypnotics and Sedatives; Infant; Intensive Care | 2006 |
Effects of escitalopram on ethanol withdrawal syndrome in rats.
Topics: Alcohol Drinking; Animals; Antidepressive Agents; Central Nervous System Depressants; Citalopram; Do | 2006 |
[A 74-year-old unconscious woman with myoclonia and seizures].
Topics: Aged; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Citalopram; F | 2006 |
Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant-anticonvulsant action.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Chromatography, L | 2008 |
Effects of 6-methoxy-1,2,3,4-tetrahydro-beta-carboline (6-MeO-THbetaC) on audiogenic seizures in DBA/2J mice.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Benzofurans; Carbolines; Citalopram; Clomipramin | 1980 |
Effects of norepinephrine and 5-hydroxytryptamine reuptake inhibitors on electrically-induced spinal cord seizures in rats.
Topics: Animals; Benzofurans; Citalopram; Desipramine; Electric Stimulation; Female; Fluoxetine; Norepinephr | 1980 |
The anticonvulsant effect of citalopram on El mice, and the levels of tryptophan and tyrosine and their metabolites in the brain.
Topics: Animals; Anticonvulsants; Brain; Cerebral Cortex; Citalopram; Corpus Striatum; Hippocampus; Homovani | 1994 |
Citalopram overdose--review of cases treated in Swedish hospitals.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Citalopram; Dose-Response Relationship, Drug; Drug Inter | 1997 |
Symptoms and signs of severe citalopram overdose.
Topics: Adult; Antidepressive Agents; Charcoal; Citalopram; Drug Overdose; Electrocardiography; Female; Gast | 1997 |
[Picture of poisoning in citalopram overdose. Convulsions and ECG symptoms can occur].
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Citalopram; Drug Interactions; Drug Overdose; Electr | 1997 |
Citalopram toxicity.
Topics: Antidepressive Agents; Citalopram; Drug Overdose; Humans; Seizures; Selective Serotonin Reuptake Inh | 1997 |
Chronic antidepressant treatments decrease pro-opiomelanocortin mRNA expression in the pituitary gland: effects of acute stress and 5-HT(1A) receptor activation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acute Disease; Animals; Antidepressive Agents; Citalopram; G | 2001 |
The effect of antidepressant drugs on the locomotor hyperactivity induced by MK-801, a non-competitive NMDA receptor antagonist.
Topics: Animals; Antidepressive Agents; Benzazepines; Citalopram; Dizocilpine Maleate; Fluoxetine; Imipramin | 1992 |