nitrazepam has been researched along with Seizures in 24 studies
Nitrazepam: A benzodiazepine derivative used as an anticonvulsant and hypnotic.
nitrazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one which is substituted at positions 5 and 7 by phenyl and nitro groups, respectively. It is used as a hypnotic for the short-term management of insomnia and for the treatment of epileptic spasms in infants (West's syndrome).
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The anticonvulsant effects of clonazepam, nitrazepam and chlordiazepoxide alone, or combined with diphenylhydantoin, were studied on pentylenetetrazol- and bicuculline-induced seizures." | 7.66 | Effects of combined treatment with diphenylhydantoin and different benzodiazepines on pentylenetetrazol- and bicuculline-induced seizures in mice. ( Czuczwar, SJ; Kleinrok, Z; Turski, L, 1982) |
| "The anticonvulsant effects of clonazepam, nitrazepam and chlordiazepoxide alone, or combined with diphenylhydantoin, were studied on pentylenetetrazol- and bicuculline-induced seizures." | 3.66 | Effects of combined treatment with diphenylhydantoin and different benzodiazepines on pentylenetetrazol- and bicuculline-induced seizures in mice. ( Czuczwar, SJ; Kleinrok, Z; Turski, L, 1982) |
| "Diazepam, oxazepam, N-methyloxazepam, nitrazepam and N-desmethyldiazepam prevented seizures in mice produced by lidocaine, mepivacaine, and prilocaine, and in rats by lidocaine when administered IP five minutes before IP local anesthetic." | 3.66 | Structure activity relationships of selected benzodiazepines as anticonvulsants to local anesthetics. ( Coffman, WB; McFarland, SA; Meyer, EA; Mumford, R; Wynn, RL, 1980) |
| "The therapeutics results with the use of different drugs (diazepam, nitrazepam, clonazepam, diphenylhydantoin, barbiturates--phenobarbital and primidone--, sodium dipropylacetate and ACTH) in twenty-nine patients with Lennox--Gastaut syndrome are carefully analysed." | 3.65 | [Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome]. ( Lison, MP; Speciali, GG, 1977) |
| " The controls were comprised of naive rats (G-VI) and naive rats dosed in the same manner as the dependent rats." | 1.26 | Participant of serotonin turnover rate in the brain on barbital withdrawal convulsion. ( Hiramori, T; Nakao, K; Tagashira, E; Urano, T; Yanaura, S, 1982) |
| "Comparison of the PD50 from clonic seizure at the peak-effect hours revealed that the benzodiazepines were 16 to 96 times more potent than phenobarbitone on a molar basis, while phenobarbitone itself was 12 to 26 times more potent than ethosuximide and trimethadione." | 1.26 | The temporal dimensions of anticonvulsant action of some newer benzodiazepines against metrazol induced seizures in mice and rats. ( Banerjee, U; Yeoh, PN, 1977) |
| "Different strengths of seizure foci were induced by penicillin G 1000, 3000 and 6000 U injected into the cortex, amygdala and intralaminal thalamus, and the spread of epileptic discharges in the subcortex or surrounding area and to the contralateral area was followed." | 1.26 | [Depressive effects of benzodiazepines on penicillin-induced epileptic discharges]. ( Fukushima, H; Kitagawa, S; Tsuchiya, T, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (91.67) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lukovits, I | 1 |
| Lopata, A | 1 |
| Belozertsev, IuA | 1 |
| Shchelkanova, OA | 1 |
| Belozertsev, FIu | 1 |
| Iuntsev, SV | 1 |
| Czuczwar, SJ | 1 |
| Turski, L | 1 |
| Kleinrok, Z | 1 |
| Tagashira, E | 1 |
| Hiramori, T | 1 |
| Urano, T | 1 |
| Nakao, K | 1 |
| Yanaura, S | 1 |
| Wynn, RL | 1 |
| McFarland, SA | 1 |
| Meyer, EA | 1 |
| Coffman, WB | 1 |
| Mumford, R | 1 |
| Mares, P | 1 |
| Seidl, J | 1 |
| Suzuki, Y | 1 |
| Nagai, T | 1 |
| Okada, S | 1 |
| Ritson, EB | 1 |
| Speciali, GG | 1 |
| Lison, MP | 1 |
| Banerjee, U | 1 |
| Yeoh, PN | 1 |
| Tsuchiya, T | 1 |
| Fukushima, H | 1 |
| Kitagawa, S | 1 |
| Berman, W | 1 |
| Wyllie, E | 1 |
| Wyllie, R | 1 |
| Cruse, RP | 1 |
| Rothner, AD | 1 |
| Erenberg, G | 1 |
| Helwig, H | 1 |
| Greenblatt, DJ | 1 |
| Shader, RI | 1 |
| Browne, TR | 1 |
| Penry, JK | 1 |
| Alberti, G | 1 |
| De Toma, M | 1 |
| Cottini, R | 1 |
| Ferngren, H | 1 |
| Hellström, B | 1 |
| Hagberg, B | 1 |
| Hansson, O | 1 |
| Vassella, F | 1 |
| Pavlincova, E | 1 |
| Schneider, HJ | 1 |
| Rudin, HJ | 1 |
| Karbowski, K | 1 |
| Hooshmand, H | 1 |
| Suter, CG | 1 |
| Dennis, J | 1 |
| Bower, BD | 1 |
| Tassinari, CA | 1 |
| Dravet, C | 1 |
| Roger, J | 1 |
| Cano, JP | 1 |
| Gastaut, H | 1 |
| Lipp, JA | 1 |
3 reviews available for nitrazepam and Seizures
| Article | Year |
|---|---|
[Psychopharmacological agents in children].
Topics: Acetylcholine; Aminobutyrates; Antipsychotic Agents; Cerebral Palsy; Child; Chlordiazepoxide; Diazep | 1973 |
Drug therapy. Benzodiazepines (second of two parts).
Topics: Affective Symptoms; Alcoholism; Analgesia; Anesthesia, General; Anesthesia, Obstetrical; Anti-Anxiet | 1974 |
Benzodiazepines in the treatment of epilepsy. A review.
Topics: Adult; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Disease Models, Animal; Eclampsia; Elec | 1973 |
21 other studies available for nitrazepam and Seizures
| Article | Year |
|---|---|
Decomposition of pharmacological activity indices into mutually independent components using principal component analysis.
Topics: Animals; Anti-Infective Agents; Benzodiazepines; Hydroxyquinolines; Mathematics; Pharmacology; Rifam | 1980 |
[Comparative evaluation of the hypnotic drugs under conditions of brain injury].
Topics: Animals; Azabicyclo Compounds; Brain Injuries; Hypnotics and Sedatives; Hypoxia; Injections, Intrape | 2012 |
Effects of combined treatment with diphenylhydantoin and different benzodiazepines on pentylenetetrazol- and bicuculline-induced seizures in mice.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Chlordiazepoxide; Clonazepam; Dose-Response Relationship, | 1982 |
Participant of serotonin turnover rate in the brain on barbital withdrawal convulsion.
Topics: Animals; Barbital; Barbiturates; Brain; Chlorpromazine; Humans; Hydroxyindoleacetic Acid; Male; Nitr | 1982 |
Structure activity relationships of selected benzodiazepines as anticonvulsants to local anesthetics.
Topics: Anesthetics, Local; Animals; Anticonvulsants; Benzodiazepines; Diazepam; Lidocaine; Male; Mepivacain | 1980 |
Anti-metrazol effects of nitrazepam during ontogenesis in the rat.
Topics: Age Factors; Animals; Animals, Newborn; Male; Nitrazepam; Pentylenetetrazole; Rats; Rats, Inbred Str | 1982 |
[Influence of co-administered antiepileptic drugs on nitrazepam tolerance in mice].
Topics: Animals; Anticonvulsants; Benzodiazepines; Disease Models, Animal; Drug Interactions; Drug Therapy, | 1998 |
Psychological medicine. Treatment of alcoholism.
Topics: Adolescent; Adult; Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholics Anonymous; Alcoholism; | 1975 |
[Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, Preschool; Clonazepam; Dia | 1977 |
The temporal dimensions of anticonvulsant action of some newer benzodiazepines against metrazol induced seizures in mice and rats.
Topics: Animals; Benzodiazepines; Clonazepam; Diazepam; Drug Evaluation, Preclinical; Ethosuximide; Female; | 1977 |
[Depressive effects of benzodiazepines on penicillin-induced epileptic discharges].
Topics: Animals; Benzodiazepines; Cats; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Electroencep | 1976 |
Letter: The ketogenic diet, West and Lennox syndromes.
Topics: Child; Child, Preschool; Clonazepam; Diazepam; Humans; Infant; Intellectual Disability; Myoclonus; N | 1975 |
The mechanism of nitrazepam-induced drooling and aspiration.
Topics: Child; Deglutition; Deglutition Disorders; Esophagus; Female; Humans; Infant; Male; Manometry; Muscl | 1986 |
[Epilepsy in childhood].
Topics: Adrenocorticotropic Hormone; Child; Child, Preschool; Electroencephalography; Epilepsy; Epilepsy, Ab | 1972 |
[Anticonvulsants. 6. Treatment of infantile spasm with hypsarrhythmia].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Benzazepines; Brain Damage, Chronic; Child; Child, P | 1971 |
[Anticonvulsants. 7. Treatment of myclonic-astatic epilepsy in small children].
Topics: Acetazolamide; Adrenocorticotropic Hormone; Child, Preschool; Diazepam; Epilepsy, Absence; Epilepsy, | 1971 |
Treatment of infantile spasms and Lennox-Gastaut syndrome with clonazepam (Rivotril).
Topics: Adrenocorticotropic Hormone; Alanine Transaminase; Alkaline Phosphatase; Anticonvulsants; Aspartate | 1973 |
Classification and treatment of seizure disorders in children.
Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, | 1970 |
The Aicardi syndrome.
Topics: Abnormalities, Multiple; Agenesis of Corpus Callosum; Brain; Cerebral Cortex; Electroencephalography | 1972 |
Tonic status epilepticus precipitated by intravenous benzodiazepine in five patients with Lennox-Gastaut syndrome.
Topics: Adolescent; Benzazepines; Child; Consciousness; Diazepam; Electroencephalography; Epilepsy, Absence; | 1972 |
Effect of benzodiazepine derivatives on soman-induced seizure activity and convulsions in the monkey.
Topics: Animals; Benzazepines; Cholinesterase Inhibitors; Diazepam; Dose-Response Relationship, Drug; Electr | 1973 |