edaravone has been researched along with Seizures in 9 studies
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To explore the effect of edaravone (ED) on apoptosis of hippocampus neurons in seizures rats induced by pentylenetetrazole (PTZ)." | 7.80 | Effect of edaravone on apoptosis of hippocampus neuron in seizures rats kindled by pentylenetetrazole. ( Cheng, XL; Zhang, JJ, 2014) |
| "In the IP PTZ model, edaravone increased time latencies to seizures (P<0." | 4.31 | Acute and Sub-chronic Anticonvulsant Effects of Edaravone on Seizure Induced by Pentylenetetrazole or Electroshock in Mice, Nitric Oxide Involvement. ( Dastgheib, M; Moezi, L; Oftadehgan, S; Pirsalami, F; Purkhosrow, A; Sattarinezhad, E, 2023) |
| "To explore the effect of edaravone (ED) on apoptosis of hippocampus neurons in seizures rats induced by pentylenetetrazole (PTZ)." | 3.80 | Effect of edaravone on apoptosis of hippocampus neuron in seizures rats kindled by pentylenetetrazole. ( Cheng, XL; Zhang, JJ, 2014) |
| " Edaravone increased expression of GRP78 and decreased expression of caspase-12 in hippocampus rat with pilocarpine-induced seizures, reduced the number of neuronal apoptosis." | 3.77 | [Effects of edaravone on the expression of GRP78, Caspase-12, and neuron apoptosis in juvenile rat hippocampus after status convulsive]. ( Jiang, CM; Li, GQ; Wang, HP, 2011) |
| "Edaravone inhibited expression of IL-1beta and NF-kappaB in pilocarpine-induced seizures in rat hippocampus, reduced the number of neuronal apoptosis." | 3.75 | [Effects of edaravone on the expression of interleukin-1beta, nuclear factor-kappaB and neuron apoptosis in juvenile rat hippocampus after status convulsion]. ( Deng, XL; Li, GQ; Wang, HP, 2009) |
| "Edaravone pretreatment suppressed epileptiform activity by reducing the mean spike frequency and the behavior scores in ECoG recording." | 1.62 | Anticonvulsive effects of edaravone on penicillin-induced focal onset seizure model in the conscious rats. ( Aygun, H; Kurt, S, 2021) |
| "The kainic acid (KA) model of induced seizures has been widely used to study temporal lobe epilepsy." | 1.40 | 3-Methyl-1-phenyl-2-pyrazolin-5-one or N-acetylcysteine prevents hippocampal mossy fiber sprouting and rectifies subsequent convulsive susceptibility in a rat model of kainic acid-induced seizure ceased by pentobarbital. ( Fukui, M; Miyamoto, R; Nomura, S; Shimakawa, S; Tamai, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Moezi, L | 1 |
| Pirsalami, F | 1 |
| Dastgheib, M | 1 |
| Oftadehgan, S | 1 |
| Purkhosrow, A | 1 |
| Sattarinezhad, E | 1 |
| Hao, L | 1 |
| Dong, L | 1 |
| Yu, Q | 1 |
| Shen, W | 1 |
| Wei, X | 1 |
| Kurt, S | 1 |
| Aygun, H | 1 |
| Cheng, XL | 1 |
| Zhang, JJ | 1 |
| Nomura, S | 1 |
| Shimakawa, S | 1 |
| Miyamoto, R | 1 |
| Fukui, M | 1 |
| Tamai, H | 1 |
| Baba, A | 1 |
| Kawakami, Y | 1 |
| Saito, K | 1 |
| Murashima, YL | 1 |
| Itoh, Y | 1 |
| Wang, HP | 3 |
| Deng, XL | 2 |
| Li, GQ | 3 |
| Jiang, CM | 1 |
9 other studies available for edaravone and Seizures
| Article | Year |
|---|---|
Acute and Sub-chronic Anticonvulsant Effects of Edaravone on Seizure Induced by Pentylenetetrazole or Electroshock in Mice, Nitric Oxide Involvement.
Topics: Animals; Anticonvulsants; Edaravone; Electroshock; Enzyme Inhibitors; Male; Mice; NG-Nitroarginine M | 2023 |
Edaravone inhibits procaspase-3 denitrosylation and activation through FasL-Trx2 pathway in KA-induced seizure.
Topics: Animals; Caspase 3; Disease Models, Animal; Edaravone; Fas Ligand Protein; Kainic Acid; Male; Neurop | 2020 |
Anticonvulsive effects of edaravone on penicillin-induced focal onset seizure model in the conscious rats.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Edaravone; Injec | 2021 |
Effect of edaravone on apoptosis of hippocampus neuron in seizures rats kindled by pentylenetetrazole.
Topics: Animals; Antipyrine; Apoptosis; Caspase 3; Edaravone; fas Receptor; Hippocampus; Kindling, Neurologi | 2014 |
3-Methyl-1-phenyl-2-pyrazolin-5-one or N-acetylcysteine prevents hippocampal mossy fiber sprouting and rectifies subsequent convulsive susceptibility in a rat model of kainic acid-induced seizure ceased by pentobarbital.
Topics: Acetylcysteine; Aldehydes; Animals; Anticonvulsants; Antipyrine; Cell Survival; Edaravone; Excitator | 2014 |
Effects of Edaravone on Hippocampal Antioxidants in EL Mice.
Topics: Action Potentials; Animals; Antioxidants; Antipyrine; Edaravone; Electroencephalography; Glutathione | 2016 |
[Effects of edaravone on the expression of interleukin-1beta, nuclear factor-kappaB and neuron apoptosis in juvenile rat hippocampus after status convulsion].
Topics: Animals; Antipyrine; Apoptosis; Edaravone; Hippocampus; Interleukin-1beta; Male; Neurons; NF-kappa B | 2009 |
[Effects of edaravone on glial fibrillary acidic protein and interleukin-lβ expression and neuronal apoptosis in juvenile rat hippocampus after status convulsion].
Topics: Animals; Antipyrine; Apoptosis; Edaravone; Free Radical Scavengers; Glial Fibrillary Acidic Protein; | 2011 |
[Effects of edaravone on the expression of GRP78, Caspase-12, and neuron apoptosis in juvenile rat hippocampus after status convulsive].
Topics: Animals; Antipyrine; Apoptosis; Caspase 12; Edaravone; Heat-Shock Proteins; Hippocampus; Male; Rats; | 2011 |