A fatty-acid amide hydrolase 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q6GMR7]
EC 3.5.1.99;
Amidase domain-containing protein;
Anandamide amidohydrolase 2;
Oleamide hydrolase 2
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| urb 597 | Homo sapiens (human) | IC50 | 0.0050 | 1 | 1 |
| ol-135 | Homo sapiens (human) | IC50 | 0.0134 | 1 | 1 |
| pf 3845 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
This protein enables 1 target(s):
| Target | Category | Definition |
|---|---|---|
| fatty acid amide hydrolase activity | molecular function | Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid. [PMID:15952893] |
This protein is located in 2 target(s):
| Target | Category | Definition |
|---|---|---|
| lipid droplet | cellular component | An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. [GOC:mah, GOC:tb] |
| membrane | cellular component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
This protein is involved in 2 target(s):
| Target | Category | Definition |
|---|---|---|
| lipid catabolic process | biological process | The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. [GOC:go_curators] |
| arachidonic acid metabolic process | biological process | The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer. [ISBN:0198506732] |