1-methyl-3-isobutylxanthine has been researched along with Seizures in 2 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When isbufylline-pretreated rats were challenged with pentylenetetrazole, the EEG was characterized by a short run of wave discharges (whose duration was shorter than that of other groups)." | 5.28 | Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study. ( Bortot, L; Cutrufo, C; Giachetti, A; Manzini, S, 1992) |
| "When isbufylline-pretreated rats were challenged with pentylenetetrazole, the EEG was characterized by a short run of wave discharges (whose duration was shorter than that of other groups)." | 1.28 | Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study. ( Bortot, L; Cutrufo, C; Giachetti, A; Manzini, S, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Snyder, SH | 1 |
| Sklar, P | 1 |
| Cutrufo, C | 1 |
| Bortot, L | 1 |
| Giachetti, A | 1 |
| Manzini, S | 1 |
2 other studies available for 1-methyl-3-isobutylxanthine and Seizures
| Article | Year |
|---|---|
Behavioral and molecular actions of caffeine: focus on adenosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Anxiety Disorders; Behavior; Caffeine; Child; Cycli | 1984 |
Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, | 1992 |