phenylbutazone has been researched along with Seizures in 9 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The muscarinic cholinergic agonist pilocarpine induces in rats seizures and status epilepticus followed by widespread damage to the forebrain." | 7.67 | Differential effects of non-steroidal anti-inflammatory drugs on seizures produced by pilocarpine in rats. ( Bortolotto, ZA; Calderazzo-Filho, LS; Cavalheiro, EA; Ikonomidou-Turski, C; Kleinrok, Z; Turski, L; Turski, WA, 1988) |
| "The muscarinic cholinergic agonist pilocarpine induces in rats seizures and status epilepticus followed by widespread damage to the forebrain." | 3.67 | Differential effects of non-steroidal anti-inflammatory drugs on seizures produced by pilocarpine in rats. ( Bortolotto, ZA; Calderazzo-Filho, LS; Cavalheiro, EA; Ikonomidou-Turski, C; Kleinrok, Z; Turski, L; Turski, WA, 1988) |
| "Phenylbutazone is a potent nonsteroidal, anti-inflammatory drug often used by veterinarians to treat racetrack animals." | 1.28 | Poisoning with equine phenylbutazone in a racetrack worker. ( Newton, TA; Rose, SR, 1991) |
| "She then developed generalized convulsions." | 1.26 | [Atypical late onset of clinical symtoms after phenylbutazone/amidopyrine ingestion (author's transl)]. ( Pohlandt, F; Töllner, U, 1976) |
| "Phenylbutazone treatment increased the potency of DPH in terms of dose and total drug concentration but did not affect the potency of unbound DPH." | 1.25 | Diphenylhydantoin potency and plasma protein binding. ( Azarnoff, DL; Shoeman, DW, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Emele, JF | 1 |
| Shanaman, JE | 1 |
| Töllner, U | 1 |
| Pohlandt, F | 1 |
| Shoeman, DW | 1 |
| Azarnoff, DL | 1 |
| Newton, TA | 1 |
| Rose, SR | 1 |
| Ikonomidou-Turski, C | 1 |
| Cavalheiro, EA | 1 |
| Turski, L | 1 |
| Bortolotto, ZA | 1 |
| Kleinrok, Z | 1 |
| Calderazzo-Filho, LS | 1 |
| Turski, WA | 1 |
| Tubaro, E | 1 |
| Banci, F | 1 |
| Caprino, L | 2 |
| Borrelli, F | 2 |
| Falchetti, R | 2 |
| Akimoto, T | 1 |
| Tsukada, W | 1 |
| Yamasaki, T | 1 |
| Kojima, H | 1 |
| Kasahara, A | 1 |
9 other studies available for phenylbutazone and Seizures
| Article | Year |
|---|---|
Analgesic acitivity of namoxyrate (2-[4-biphenylyl] butyric acid 2-dimethylaminoethanol salt).
Topics: Amino Alcohols; Analgesics; Animals; Aspirin; Biphenyl Compounds; Bradykinin; Butyrates; Codeine; De | 1967 |
[Atypical late onset of clinical symtoms after phenylbutazone/amidopyrine ingestion (author's transl)].
Topics: Alanine Transaminase; Aminopyrine; Aspartate Aminotransferases; Child, Preschool; Diuresis; Female; | 1976 |
Diphenylhydantoin potency and plasma protein binding.
Topics: Administration, Oral; Animals; Blood Proteins; Drug Synergism; Electroshock; Male; Phenylbutazone; P | 1975 |
Poisoning with equine phenylbutazone in a racetrack worker.
Topics: Acute Kidney Injury; Adult; Animals; Chemical and Drug Induced Liver Injury; Coma; Dogs; Drug Overdo | 1991 |
Differential effects of non-steroidal anti-inflammatory drugs on seizures produced by pilocarpine in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Male; Mefenamic Acid; Phenylbutazone; Piloc | 1988 |
Pharmacology of a nicotinamido-methylaminopyrazolone (Ra 101).
Topics: Aminopyrine; Amphetamine; Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Carrageena | 1970 |
Pharmacological research on 4,5-diphenyl-2-bis(2-hydroxyethyl)-aminoxazol (Ditazol), a new synthetic oxazole derivative as an anti-inflammatory agent.
Topics: Administration, Oral; Administration, Topical; Adrenalectomy; Analgesics; Animals; Anti-Inflammatory | 1973 |
General pharmacological properties of 4,5-diphenyl-2-bis-(2-hydroxyethyl)-aminoxazol (ditazol).
Topics: Amphetamine; Animals; Anti-Inflammatory Agents; Atropine; Blood Pressure; Cats; Chlorpromazine; Etha | 1973 |
[Pharmacological studies on 1-(4-methoxy-6-methyl-2-pyrimidinyl)-3-methyl-5-methoxypyrazole (DA-398), a new anti-inflammatory agent].
Topics: Adrenal Glands; Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Antitussive Agents; Anur | 1969 |