thiazoles has been researched along with Seizures in 75 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (24.00) | 18.7374 |
| 1990's | 20 (26.67) | 18.2507 |
| 2000's | 17 (22.67) | 29.6817 |
| 2010's | 14 (18.67) | 24.3611 |
| 2020's | 6 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ammar, YA; Bayoumi, AH; Ezz Eldin, RR; Fayed, EA; Ragab, A | 1 |
| de Oliveira, MCVA; Duarte, FS; Pereira, MC; Pitta, IR; Pitta, MGR; Silva, AA; Viana, DCF | 1 |
| Antonova, IV; Dyomina, AV; Griflyuk, AV; Kovalenko, AA; Postnikova, TY; Smolensky, IV; Zaitsev, AV; Zakharova, MV | 1 |
| Cheng, X; Liu, D; Wang, Y | 1 |
| Biag, JD; Bonazzi, S; Burdette, D; Curtis, D; Deng, L; Dodart, JC; Goold, CP; Gorde, A; Gray, A; Hamann, LG; Karki, RG; Keaney, EP; Labbe-Giguere, N; Liang, G; Liu, S; Lombardo, F; Lubicka, D; Malik, HA; McTighe, S; Murphy, LO; Nunez, J; Peukert, S; Piizzi, G; Salas, S; Sun, Y; Thomsen, NM; Wilson, CJ | 1 |
| Khisal, S; Mishra, R; Partap, S; Siddiqui, AA; Yar, MS | 1 |
| Danzer, SC; Gross, C; MacLeod, MC; Tiwari, D; White, AR | 1 |
| An, XF; Liu, XJ; Yang, GS; Yu, D; Zhang, YJ; Zhou, XY | 1 |
| Barkhof, F; Boon, BDC; Groot, C; Ikonomovic, MD; Klunk, WE; Lammertsma, AA; Ossenkoppele, R; Rozemuller, AJM; Scheltens, P; Tolboom, N; van Berckel, BNM | 1 |
| Benke, TA; Bernard, PB; Browning, MD; Castano, AM; O'Leary, H; Simpson, K | 1 |
| Bahare, RS; Khan, SA; Malik, S | 1 |
| Deng, XQ; Liu, DC; Quan, ZS; Wang, SB | 1 |
| Avoli, M; D'Antuono, M; Hamidi, S | 1 |
| Al-Omar, MA; Al-Rashood, STA; El-Messery, SM; El-Subbagh, HI; El-Taher, KEH; Hassan, GS; Hefnawy, MM | 1 |
| Malikowska, N; Misiura, K; Podkowa, A; Sałat, K; Łączkowski, KZ | 1 |
| Mishra, M; Saraf, SK; Shukla, R; Singh, AP; Sonar, PK | 1 |
| Baranowska-Łączkowska, A; Biernasiuk, A; Furgała, A; Malm, A; Misiura, K; Sałat, K; Zielińska, S; Łączkowski, KZ | 1 |
| Choi, H; Hong, JT; Kim, Y; Kim, YB; Lee, K; Ma, Y; Nam, SY; Oh, KW; Yun, SR | 1 |
| Heard, K; Krier, S; Zahniser, NR | 1 |
| Bauchwitz, RP; Chen, S; Jope, RS; Min, WW; Sikorski, C; Yan, Q; Yuskaitis, CJ | 1 |
| Boeck, CR; Carqueja, CL; Dal'agnolo, D; de Araújo Herculano, B; Martins, WC; Piermartiri, TC; Stroeh, E; Tasca, CI; Vandresen-Filho, S | 1 |
| Bochenski, M; Danysz, W; Kotlinska, JH | 1 |
| Aizenman, CD; Spawn, A | 1 |
| Erdur, B; Ergin, A; Kortunay, S; Yuksel, A | 1 |
| Atack, JR; Broughton, HB; Chambers, MS; Collinson, N; Cook, S; Dawson, GR; Hobbs, SC; MacLeod, AM; Marshall, G; Maubach, KA; Pillai, GV; Reeve, AJ | 1 |
| Hedges, D; Jeppson, K; Whitehead, P | 1 |
| FEATHERSTON, WM | 1 |
| HOLOWACH, J; O'LEARY, JL; THURSTON, DL | 1 |
| CHRISTEN, JP; JACCOTTET, M | 1 |
| MORTON, K | 1 |
| CHEN, G; ENSOR, CR | 1 |
| Dubois, D | 1 |
| Cleveland, NJ; Dewitt, CD; Heard, K | 1 |
| Chechlacz, M; Gilliams-Francis, K; Lamonica, K; Lin, SL; Liu, J; Naegele, JR; Navarro-Quiroga, I; Neema, M | 1 |
| Alp, FI; Altintaş, H; Atana, D; Ateş, O; Birteksöz, S; Kaleli, D; Otük, G; Ozdemir, O; Uyde-Doğan, BS; Uzun, M | 1 |
| Akkaya, C; Kirli, S; Kotan, Z; Sarandol, A; Sivrioglu, EY | 1 |
| Chai, KY; Jin, HG; Piao, HR; Quan, ZS; Sun, XY | 1 |
| Beno, DW; Beutel, BA; Blomme, EA; Camp, HS; Carroll, SL; Clark, RF; Gu, YG; Hansen, TM; Healan-Greenberg, CH; Keyes, RF; Li, Q; Lubbers, NL; Sham, HL; Wang, R; Wang, X; Waring, JF; Weitzberg, M; Widomski, DL; Xu, X; Yang, Y; Zhang, T | 1 |
| Fishback, JA; Green, AM; Kaushal, N; Matsumoto, RR; McCurdy, CR; Mésangeau, C; Narayanan, S; Poupaert, JH; Shaikh, J; Viard, E; Xu, YT | 1 |
| Efthymiou, ML; Fournier, E; Garnier, R | 1 |
| Kahn, RS; Manoguerra, AS | 1 |
| Anderson, JA; Dostal, LA | 1 |
| Caliş, U; Demirdamar, R; Erol, DD; Ertan, M; Yuluğ, N | 1 |
| Barreau, M; Blanchard, JC; Boireau, A; Doble, A; Jimonet, P; Laduron, P; Lavayre, J; Malgouris, C; Piot, O; Pratt, J | 1 |
| Iinuma, K; Onodera, K; Watanabe, T; Yokoyama, H | 1 |
| Chantegrel, J; de Lima, JG; Luu-Duc, C; Narcisse, G; Perrissin, M; Rousseau, A | 1 |
| Barta-Szalai, G; Domány, G; Pálosi, E; Schön, I; Szabó, S | 1 |
| Capan, G; Ergenç, N | 1 |
| Debarnot, F; Mary, V; Pratt, J; Rataud, J; Stutzmann, JM | 1 |
| el-Feky, SA | 1 |
| Chimirri, A; DeSarro, A; DeSarro, GB; Grasso, S; Zappalà, M | 1 |
| Biggio, G; Carotti, A; Cellamare, S; Franco, M; Ghiani, CA; Latrofa, A; Liso, G; Serra, M; Trapani, G; Tuligi, G | 1 |
| Cacciaguerra, S; Isa, M; Kanyonyo, M; Poupaert, JH; Spampinato, S; Ucar, H; Van derpoorten, K | 1 |
| Eid, NM; el-Tawab, HA; Ragab, FA | 1 |
| Cacciaguerra, S; Delarge, J; Depovere, P; Isa, M; Masereel, B; Poupaert, JH; Spampinato, S; Stables, JP; Ucar, H; Van derpoorten, K | 1 |
| Horga, JF; Javaloy, J; Román, JF; Vidal, MT; Zapater, P | 1 |
| Meade, HM; Seeley, NA; Sturman, G | 1 |
| Audiau, F; Barreau, M; Blanchard, JC; Boireau, A; Bour, Y; Coléno, MA; Doble, A; Doerflinger, G; Donat, MH; Duchesne, JM; Ganil, P; Gontier, S; Guérémy, C; Honor, E; Hubert, P; Huu, CD; Jimonet, P; Just, B; Kerphirique, R; Laduron, PM; Le Blevec, J; Meunier, M; Mignani, S; Miquet, JM; Nemecek, C | 1 |
| Amiridze, N; Brown, OR; Dale, WE; Dang, Y | 1 |
| Camandola, S; Chan, SL; Culmsee, C; Greig, NH; Guo, Z; Mattson, MP; Yu, QS; Zhu, X | 1 |
| Seeley, N; Sturman, G | 1 |
| Couturier, C | 1 |
| Pandeya, SN; Siddigui, N | 1 |
| Bodewei, R; Fischer, W; Satzinger, G | 1 |
| Blanchard, JC; Böhme, GA; Gandolfo, G; Gottesmann, C; Laduron, PM; Lafforgue, J; Lazdunski, M; Stutzmann, JM | 1 |
| Croucher, M; Gueremy, C; Le Fur, G; Legrand, JJ; Mazadier, M; Meldrum, B; Mizoule, J; Ollat, C; Uzan, A | 1 |
| Aguilar Barberá, M; Cardesin Castro, R; Peres Serra, J; Reñé Ramírez, R | 1 |
| Fujii, T; Ito, N; Miyazaki, K; Takashima, T; Watanabe, N | 1 |
| Lazzari, R; Paolucci, G | 1 |
| Barthwal, JP; Brumleve, SJ; Misra, RS; Parmar, SS | 1 |
| Inoki, R; Otori, K; Yamamoto, I | 1 |
| Dwivedi, C; Gupta, TK; Parmar, SS | 1 |
| Barreto, FT; Coutinho, A | 1 |
| Bell, RR; Smith, JP | 1 |
2 review(s) available for thiazoles and Seizures
| Article | Year |
|---|---|
Antipsychotic medication and seizures: a review.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Quinolones; Risperidone; Seizures; Thiazoles | 2003 |
Toxicology and overdose of atypical antipsychotic medications in children: does newer necessarily mean safer?
Topics: Antipsychotic Agents; Aripiprazole; Basal Ganglia Diseases; Benzodiazepines; Cardiomyopathies; Child; Clozapine; Diabetes Mellitus; Dibenzothiazepines; Drug Interactions; Drug Overdose; Dry Eye Syndromes; Humans; Hyperlipidemias; Hypotension; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Seizures; Thiazoles | 2005 |
73 other study(ies) available for thiazoles and Seizures
| Article | Year |
|---|---|
In vivo screening and toxicity studies of indolinone incorporated thiosemicarbazone, thiazole and piperidinosulfonyl moieties as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Injections, Intraperitoneal; Male; Mice; Molecular Structure; Oxindoles; Pentylenetetrazole; Piperidines; Seizures; Structure-Activity Relationship; Thiazoles; Thiosemicarbazones | 2021 |
Synthesis of novel thiazolidinic-phthalimide derivatives evaluated as new multi-target antiepileptic agents.
Topics: Animals; Anticonvulsants; Cells, Cultured; Dose-Response Relationship, Drug; Epilepsy; Humans; Male; Molecular Docking Simulation; Molecular Structure; Phthalimides; Rats; Rats, Wistar; Seizures; Structure-Activity Relationship; Thiazoles | 2022 |
MTEP, a Selective mGluR5 Antagonist, Had a Neuroprotective Effect but Did Not Prevent the Development of Spontaneous Recurrent Seizures and Behavioral Comorbidities in the Rat Lithium-Pilocarpine Model of Epilepsy.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Epilepsy; Hippocampus; Lithium; Male; Neurons; Neuroprotective Agents; Pilocarpine; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Seizures; Thiazoles | 2022 |
Design, Synthesis and Biological Evaluation of Benzo[D]Thiazole with Dimethylpyrazol Derivatives.
Topics: Animals; Anticonvulsants; Benzothiazoles; Cell Line, Tumor; GABA Agents; Humans; Mice; Seizures; Synaptic Transmission; Thiazoles | 2019 |
Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders.
Topics: Animals; Anticonvulsants; Binding Sites; Brain; Drug Discovery; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Neurons; Protein Binding; Protein Kinase Inhibitors; Pyrimidines; Rats; Seizures; Thiazoles; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 1 Protein | 2020 |
Synthesis, anti-convulsant activity and molecular docking study of novel thiazole pyridazinone hybrid analogues.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Female; Injections, Subcutaneous; Male; Mice; Molecular Docking Simulation; Molecular Structure; Pentylenetetrazole; Pyridazines; Seizures; Structure-Activity Relationship; Thiazoles | 2020 |
PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes.
Topics: Adenine; Animals; Cerebral Cortex; Class I Phosphatidylinositol 3-Kinases; Epilepsy; Female; Hippocampus; Male; Megalencephaly; Mice; Neurons; Phosphoinositide-3 Kinase Inhibitors; PTEN Phosphohydrolase; Quinazolines; Seizures; Thiazoles | 2020 |
Synergistic effect of mild hypothermia and the Notch inhibitor DAPT against post stroke seizures.
Topics: Animals; Cerebral Cortex; Diamines; Down-Regulation; Hippocampus; Hypothermia; Kainic Acid; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Notch; Seizures; Signal Transduction; Stroke; Thiazoles; Up-Regulation | 2017 |
Quantitative PET and Histology of Brain Biopsy Reveal Lack of Selective Pittsburgh Compound-B Binding to Intracerebral Amyloidoma.
Topics: Amyloidosis; Aniline Compounds; Biopsy; Brain; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Positron-Emission Tomography; Seizures; Thiazoles | 2018 |
Phosphorylation of FMRP and alterations of FMRP complex underlie enhanced mLTD in adult rats triggered by early life seizures.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Fragile X Mental Retardation Protein; Hippocampus; In Vitro Techniques; Kainic Acid; Long-Term Synaptic Depression; Phosphorylation; Pregnancy; Protein Phosphatase 2; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Ribosomal Protein S6 Kinases, 70-kDa; Seizures; Signal Transduction; Subcellular Fractions; Thiazoles | 2013 |
Design, synthesis and anticonvulsant evaluation of N-(benzo[d]thiazol-2-ylcarbamoyl)-2-methyl-4-oxoquinazoline-3(4H)-carbothioamide derivatives: a hybrid pharmacophore approach.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Disease Models, Animal; Drug Design; Electroshock; Injections, Intraperitoneal; Mice; Molecular Structure; Quinazolines; Rats; Rats, Wistar; Seizures; Thiazoles; Thioamides | 2013 |
Synthesis and anticonvulsant activity evaluation of 7-alkoxy[1,2,4]triazolo[3,4-b]benzothiazol-3(2H)-ones.
Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Electroshock; gamma-Aminobutyric Acid; Mice; Neurotoxicity Syndromes; Seizures; Structure-Activity Relationship; Thiazoles | 2014 |
On the contribution of KCC2 and carbonic anhydrase to two types of in vitro interictal discharge.
Topics: Acetazolamide; Animals; CA3 Region, Hippocampal; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; gamma-Aminobutyric Acid; Male; Membrane Potentials; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Solute Carrier Family 12, Member 1; Thiazoles; Thioglycolates | 2015 |
Synthesis, biological evaluation and molecular modeling study of some new thiazolodiazepine analogs as CNS active agents.
Topics: Animals; Anticonvulsants; Azepines; Carboxylic Acids; GABA-A Receptor Agonists; Hypnotics and Sedatives; Mice; Models, Molecular; Pentylenetetrazole; Receptors, GABA-A; Seizures; Thiazoles | 2016 |
Synthesis and anticonvulsant activities of novel 2-(cyclopentylmethylene)hydrazinyl-1,3-thiazoles in mouse models of seizures.
Topics: Animals; Anticonvulsants; Carbon-13 Magnetic Resonance Spectroscopy; Disease Models, Animal; Male; Mass Spectrometry; Mice; Pilocarpine; Proton Magnetic Resonance Spectroscopy; Rotarod Performance Test; Seizures; Thiazoles | 2016 |
Schiff Bases of Benzothiazol-2-ylamine and Thiazolo[5,4-b] pyridin-2-ylamine as Anticonvulsants: Synthesis, Characterization and Toxicity Profiling.
Topics: Animals; Anticonvulsants; Benzothiazoles; Male; Mice; Schiff Bases; Seizures; Thiazoles; Toxicity Tests, Acute | 2016 |
Synthesis, antimicrobial and anticonvulsant screening of small library of tetrahydro-2H-thiopyran-4-yl based thiazoles and selenazoles.
Topics: Animals; Anti-Bacterial Agents; Anticonvulsants; Antifungal Agents; Candida; Dose-Response Relationship, Drug; Gram-Positive Bacteria; Male; Mice; Microbial Sensitivity Tests; Molecular Structure; Organoselenium Compounds; Seizures; Small Molecule Libraries; Structure-Activity Relationship; Thiazoles | 2016 |
Protective effects of sanjoinine A against N-methyl-D-aspartate-induced seizure.
Topics: Animals; Anticonvulsants; Calcium; Cell Survival; Cells, Cultured; Electroencephalography; Electroshock; Excitatory Amino Acid Agonists; Female; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Seizures; Tetrazolium Salts; Thiazoles; Ziziphus | 2008 |
Administration of ziprasidone for 10 days increases cocaine toxicity in mice.
Topics: Animals; Antipsychotic Agents; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Synergism; Longevity; Male; Mice; Mice, Inbred Strains; Piperazines; Seizures; Thiazoles; Time Factors; Withholding Treatment | 2008 |
Elevated glycogen synthase kinase-3 activity in Fragile X mice: key metabolic regulator with evidence for treatment potential.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Antimanic Agents; Brain; Citrates; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exploratory Behavior; Fragile X Mental Retardation Protein; Gene Expression Regulation; Glycogen Synthase Kinase 3; Indoles; Lithium Chloride; Male; Maleimides; Mice; Mice, Knockout; Pyridines; Seizures; Serine; Thiazoles; Urea | 2009 |
Atorvastatin prevents hippocampal cell death due to quinolinic acid-induced seizures in mice by increasing Akt phosphorylation and glutamate uptake.
Topics: Analysis of Variance; Animals; Atorvastatin; Cell Death; Complex Mixtures; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Male; Mice; Oncogene Protein v-akt; Phosphorylation; Pyrroles; Quinolinic Acid; Seizures; Tetrazolium Salts; Thiazoles; Tritium | 2009 |
The role of group I mGlu receptors in the expression of ethanol-induced conditioned place preference and ethanol withdrawal seizures in rats.
Topics: Animals; Conditioning, Psychological; Epilepsy, Reflex; Ethanol; Male; Motor Activity; Pyridines; Quinolines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reproducibility of Results; Seizures; Spatial Behavior; Substance Withdrawal Syndrome; Thiazoles | 2011 |
Abnormal visual processing and increased seizure susceptibility result from developmental exposure to the biocide methylisothiazolinone.
Topics: Animals; Disease Models, Animal; Disinfectants; Seizures; Thiazoles; Vision Disorders; Xenopus laevis | 2012 |
Assessment of propofol, midazolam and ziprasidone, or the combinations for the prevention of acute cocaine toxicity in a mouse model.
Topics: Animals; Anticonvulsants; Antipsychotic Agents; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Antagonists; Drug Therapy, Combination; GABA Modulators; Male; Mice; Midazolam; Piperazines; Propofol; Seizures; Serotonin Antagonists; Thiazoles | 2013 |
Identification of a novel, selective GABA(A) alpha5 receptor inverse agonist which enhances cognition.
Topics: Animals; Brain; Cell Line; Cognition; Female; GABA Agonists; Hippocampus; Humans; In Vitro Techniques; Ligands; Male; Maze Learning; Memory; Mice; Nootropic Agents; Oocytes; Patch-Clamp Techniques; Protein Subunits; Radioligand Assay; Rats; Receptors, GABA-A; Seizures; Structure-Activity Relationship; Thiazoles; Thiophenes; Xenopus laevis | 2003 |
Convulsions following use of asterol dihydrochloride; report of a case.
Topics: Antifungal Agents; Fungicides, Industrial; Seizures; Thiazoles; Tinea | 1952 |
Controlled search for neurological disturbances associated with asterol applications; preliminary report.
Topics: Antifungal Agents; Electroencephalography; Fungicides, Industrial; Seizures; Thiazoles; Tinea | 1954 |
[Convulsant poisoning in children; meta & asterol].
Topics: Acetaldehyde; Antifungal Agents; Child; Convulsants; Fungicides, Industrial; Humans; Infant; Seizures; Thiazoles | 1957 |
[Convulsions in infants caused by the cutaneous use of asterol].
Topics: Antifungal Agents; Child; Humans; Infant; Mycoses; Seizures; Thiazoles | 1961 |
Convulsions following diamthazole (asterol).
Topics: Antifungal Agents; Fungicides, Industrial; Humans; Seizures; Thiazoles | 1960 |
Anticonvulsant activities of certain thiazolidones and hydantoins as determined by electric shock procedures in cats, rats and mice.
Topics: Animals; Anticonvulsants; Cats; Convulsive Therapy; Electroshock; Hydantoins; Mice; Rats; Seizures; Thiazoles | 1949 |
Ziprasidone pretreatment attenuates the lethal effects of cocaine in a mouse model.
Topics: Acute Disease; Animals; Antipsychotic Agents; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Overdose; Injections, Intraperitoneal; Mice; Piperazines; Premedication; Random Allocation; Seizures; Single-Blind Method; Survival Analysis; Thiazoles; Treatment Outcome | 2005 |
DNA damage and nonhomologous end joining in excitotoxicity: neuroprotective role of DNA-PKcs in kainic acid-induced seizures.
Topics: Animals; Benzothiazoles; Cell Death; Cells, Cultured; DNA Damage; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Entorhinal Cortex; Excitatory Amino Acid Agonists; Heterozygote; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mitochondria; Nerve Degeneration; Neurons; Nuclear Proteins; Seizures; Thiazoles; Toluene; Tumor Suppressor Protein p53 | 2005 |
Synthesis and evaluation of antimicrobial and anticonvulsant activities of some new 3-[2- (5-aryl-1,3,4-oxadiazol-2-yl/4-carbethoxymethylthiazol-2-yl) imino-4-thiazolidinon-5-ylidene]-5-substituted/nonsubstituted 1H-indole-2-ones and investigation of thei
Topics: Anti-Infective Agents; Anticonvulsants; Antifungal Agents; Bacteria; Fungi; Gas Chromatography-Mass Spectrometry; Indicators and Reagents; Indoles; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Pentylenetetrazole; Seizures; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thiazoles | 2006 |
A patient using ziprasidone with polydipsia, seizure, hyponatremia and rhabdomyolysis.
Topics: Adult; Antipsychotic Agents; Drinking Behavior; Humans; Hyponatremia; Male; Piperazines; Rhabdomyolysis; Schizophrenia; Seizures; Thiazoles | 2006 |
Anticonvulsant and toxicity evaluation of some 7-alkoxy-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline-1(2H)-ones.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Mice; Mice, Inbred C57BL; Molecular Structure; Quinolines; Quinolones; Seizures; Stereoisomerism; Thiazoles | 2006 |
N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1-methylprop-2-ynyl}carboxy derivatives as acetyl-coA carboxylase inhibitors--improvement of cardiovascular and neurological liabilities via structural modifications.
Topics: Acetyl-CoA Carboxylase; Administration, Oral; Animals; Blood Pressure; Gene Expression; Heart Rate; Infusions, Intravenous; Male; Myocardium; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship; Thiazoles | 2007 |
Conversion of a highly selective sigma-1 receptor-ligand to sigma-2 receptor preferring ligands with anticocaine activity.
Topics: Animals; Anticonvulsants; Brain; Cocaine; Cocaine-Related Disorders; In Vitro Techniques; Ligands; Mice; Oxazoles; Piperazines; Radioligand Assay; Rats; Receptors, sigma; Seizures; Sigma-1 Receptor; Structure-Activity Relationship; Thiazoles | 2008 |
Acute thioproline poisoning.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; France; Humans; Infant; Male; Seizures; Thiazoles; Thiazolidines | 1982 |
Acute poisoning with thiazolidine carboxylic acid.
Topics: Anticonvulsants; Child, Preschool; Humans; Male; Physostigmine; Seizures; Thiazoles; Thiazolidines | 1981 |
Developmental toxicity study in rats treated with the anticonvulsant, ralitoline.
Topics: Abnormalities, Drug-Induced; Animals; Anorexia; Anticonvulsants; Aorta, Thoracic; Ataxia; Bone and Bones; Dose-Response Relationship, Drug; Female; Fetal Growth Retardation; Fetal Resorption; Lethal Dose 50; Pregnancy; Pregnancy Complications; Rats; Rats, Sprague-Dawley; Seizures; Thiazoles; Weight Gain | 1995 |
Synthesis and biological activities of some 3,6-disubstituted thiazolo[3,2-b][1,2,4]triazoles.
Topics: Animals; Anticonvulsants; Antifungal Agents; Candida; Electroshock; Male; Mice; Microbial Sensitivity Tests; Pentylenetetrazole; Seizures; Spectrophotometry, Infrared; Thiazoles; Triazoles | 1995 |
Synthesis, anticonvulsant and neuroprotective activities of RP 66055, a riluzole derivative.
Topics: Animals; Anticonvulsants; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Dopamine; Gerbillinae; Hypoxia, Brain; In Vitro Techniques; Male; Mice; Molecular Structure; Nervous System; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Seizures; Sodium Channel Blockers; Sodium Channels; Thiazoles | 1994 |
2-Thiazolylethylamine, a selective histamine H1 agonist, decreases seizure susceptibility in mice.
Topics: Animals; Anticonvulsants; Dimaprit; Dose-Response Relationship, Drug; Electroshock; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Receptors, Histamine H1; Seizures; Thiazoles | 1994 |
Synthesis and pharmacological evaluation of some 3-phenacyl-5-benzylidene-thiazolidine-2,4-diones.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Chromatography, Thin Layer; Edema; Immersion; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Rats; Seizures; Spectrophotometry, Infrared; Thiazoles | 1994 |
New 4-arylaminopiperidines with antihypoxic and anticonvulsive activity.
Topics: Animals; Anticonvulsants; Cell Survival; Cyanides; Hypoxia; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Piperidines; Seizures; Thiazoles | 1994 |
Synthesis and anticonvulsant activity of new 4-thiazolidone and 4-thiazoline derivatives.
Topics: Animals; Anticonvulsants; Electroshock; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship; Thiazoles | 1994 |
Comparative study of voltage-sensitive sodium channel blockers in focal ischaemia and electric convulsions in rodents.
Topics: Animals; Anticonvulsants; Brain Ischemia; Carbamazepine; Cerebral Arteries; Electrophysiology; Electroshock; Imidazoles; Lamotrigine; Male; Mice; Phenytoin; Piperazines; Rats; Rats, Inbred F344; Seizures; Sodium Channels; Thiazoles; Triazines | 1994 |
Synthesis and anticonvulsant properties of some novel quinazolinone thiazolidine and 4-thiazolidone derivatives.
Topics: Animals; Anticonvulsants; Female; Male; Mice; Pentylenetetrazole; Quinazolines; Seizures; Spectrophotometry, Infrared; Thiazoles | 1993 |
Molecular requirement for anticonvulsant activity in a series of thiazolo-1,4-benzodiazepine derivatives and comparison with classical benzodiazepines.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Benzodiazepines; Binding, Competitive; Body Temperature; Flumazenil; Flunitrazepam; In Vitro Techniques; Injections, Intraperitoneal; Male; Mice; Mice, Inbred DBA; Molecular Weight; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship; Thiazoles | 1993 |
Synthesis and anticonvulsant activity of some 1,2,3,3a-tetrahydropyrrolo[2,1-b]-benzothiazol-, -thiazol- or -oxazol-1-ones in rodents.
Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Isoniazid; Male; Mice; Pyrrolidines; Rats; Rats, Sprague-Dawley; Seizures; Thiazoles | 1996 |
2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives: novel, potent and selective sigma1 receptor ligands.
Topics: Animals; Anticonvulsants; Benzoxazoles; Brain; Convulsants; Electroshock; Guinea Pigs; Ligands; Male; Mice; Motor Activity; Neuroprotective Agents; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, sigma; Seizures; Sigma-1 Receptor; Structure-Activity Relationship; Thiazoles | 1997 |
Synthesis and anticonvulsant activity of new thiazolidinone and thioxoimidazolidinone derivatives derived from furochromones.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Convulsants; Imidazoles; Khellin; Male; Mice; Pentylenetetrazole; Phenobarbital; Seizures; Thiazoles | 1997 |
Synthesis and anticonvulsant activity of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives.
Topics: Animals; Anticonvulsants; Electric Stimulation; Injections, Intraperitoneal; Male; Mice; Oxazoles; Rats; Seizures; Thiazoles | 1998 |
Anticonvulsant effects of nimodipine and two novel dihydropyridines (PCA 50922 and PCA 50941) against seizures elicited by pentylenetetrazole and electroconvulsive shock in mice.
Topics: Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Clonazepam; Dihydropyridines; Electroshock; Female; Male; Mice; Mice, Inbred Strains; Nimodipine; Pentylenetetrazole; Phenytoin; Seizures; Thiazoles | 1998 |
Histamine H2-receptor modulation in two mouse models of seizure susceptibility.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Benzothiazoles; Convulsants; Dimaprit; Female; Histamine Agonists; Histamine Antagonists; Male; Mice; Mice, Inbred DBA; Pentylenetetrazole; Phenoxypropanolamines; Piperidines; Receptors, Histamine H2; Seizures; Thiazoles | 1999 |
Riluzole series. Synthesis and in vivo "antiglutamate" activity of 6-substituted-2-benzothiazolamines and 3-substituted-2-imino-benzothiazolines.
Topics: Animals; Benzothiazoles; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoxia; Imines; Injections, Intraventricular; Male; Mice; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Riluzole; Seizures; Structure-Activity Relationship; Sulfoxides; Thiazoles | 1999 |
Evidence that kynurenine pathway metabolites mediate hyperbaric oxygen-induced convulsions.
Topics: Animals; Coma; Enzyme Inhibitors; Hyperbaric Oxygenation; Kynurenine; Kynurenine 3-Monooxygenase; Male; Mixed Function Oxygenases; ortho-Aminobenzoates; Rats; Rats, Sprague-Dawley; Seizures; Sulfonamides; Thiazoles; Time Factors; Tryptophan | 2000 |
A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.
Topics: Amyloid beta-Peptides; Animals; Antineoplastic Agents; Benzothiazoles; Brain Ischemia; Caspase 3; Caspases; Cell Death; Cell Survival; Cells, Cultured; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Glutamic Acid; Kainic Acid; Mice; Mice, Inbred C57BL; Mitochondria; Neurons; Prodrugs; Rats; Rats, Sprague-Dawley; Seizures; Thiazoles; Toluene; Tumor Suppressor Protein p53 | 2001 |
Effect of amthamine, a histamine H2-agonist, in two mouse chemical-induced seizure models.
Topics: Animals; Epilepsy; Female; Histamine Agonists; Male; Mice; Receptors, Histamine H2; Seizures; Thiazoles | 2001 |
[Severe thiazolidine carboxylic acid poisoning in the child. One case (author's transl)].
Topics: Acidosis; Coma; Humans; Hyperglycemia; Infant; Male; Remission, Spontaneous; Seizures; Thiazoles | 1979 |
Evaluation of some 1,2,4-dithiazolidines as anticonvulsant agents in Wistar rats.
Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Rats; Rats, Wistar; Seizures; Structure-Activity Relationship; Thiazoles | 1992 |
Anticonvulsant and sodium channel blocking effects of ralitoline in different screening models.
Topics: Animals; Anticonvulsants; Brain; Cells, Cultured; Electric Stimulation; Male; Mice; Models, Biological; Motor Activity; Pentylenetetrazole; Phenobarbital; Rats; Rats, Wistar; Seizures; Sodium Channels; Strychnine; Thiazoles | 1992 |
Riluzole prevents hyperexcitability produced by the mast cell degranulating peptide and dendrotoxin I in the rat.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Elapid Venoms; Electroencephalography; Hippocampus; Injections, Intraventricular; Male; Peptides; Rats; Rats, Inbred Strains; Riluzole; Seizures; Thiazoles | 1991 |
2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission--I. Anticonvulsant properties.
Topics: Amino Acids; Animals; Anticonvulsants; Bicuculline; Electroshock; Female; Glutamate Decarboxylase; Harmaline; Male; Mice; Mice, Inbred DBA; Ouabain; Papio; Pentylenetetrazole; Picrotoxin; Rats; Riluzole; Seizures; Synaptic Transmission; Thiazoles | 1985 |
[Thioproline poisoning and generalized convulsive crisis].
Topics: Adult; Electroencephalography; Female; Humans; Seizures; Thiazoles; Thiazolidines | 1986 |
Toxicological and teratological studies of 4((5-chloro-2-oxo-3-benzothiazolinyl)acetyl)-1-piperazine ethanol hydrochloride (Tiaramide hydrochloride), an anti-inflammatory drug.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Inflammatory Agents; Behavior, Animal; Blood Cells; Blood Chemical Analysis; Body Weight; Dogs; Ethanol; Female; Fetus; Haplorhini; Lethal Dose 50; Macaca; Male; Mice; Organ Size; Piperazines; Pregnancy; Rabbits; Rats; Seizures; Thiazoles; Time Factors | 1973 |
[A case of poisoning due to cutaneous application of an antifungal agent].
Topics: Adrenocorticotropic Hormone; Antifungal Agents; Buttocks; Electroencephalography; Erythema; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Seizures; Thiazoles | 1968 |
Substituted benzoxazole-benzthiazole-2-thiones: interrelationship between anticonvulsant activity and inhibition of nicotinamide adenine dinucleotide-dependent oxidations and monoamine oxidase.
Topics: Aminobenzoates; Animals; Anticonvulsants; Benzoxazoles; Brain; In Vitro Techniques; Isocitrates; Ketoglutaric Acids; Monoamine Oxidase Inhibitors; NAD; Oxidation-Reduction; Pentylenetetrazole; Pyruvates; Rats; Seizures; Spectrometry, Fluorescence; Succinates; Thiazoles; Thiones | 1974 |
Pharmacological studies on antagonists against nicotine-induced convulsions and death.
Topics: Animals; Anticonvulsants; Chlorpromazine; Drug Antagonism; Female; Ganglionic Blockers; Hexamethonium Compounds; Histamine H1 Antagonists; Male; Meprobamate; Mice; Nicotine; Parasympatholytics; Perphenazine; Phenobarbital; Phentolamine; Reserpine; Seizures; Sympatholytics; Thiazoles; Tolazoline; Tranquilizing Agents; Urea | 1966 |
Substituted thiazolidones as anticonvulsants.
Topics: Animals; Anticonvulsants; Female; Ketones; Male; Mice; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Thiazoles | 1972 |
Treatment of hepatosplenic schistosomiasis mansoni with niridazole: relationships among liver function, effective dose, and side effects.
Topics: Adolescent; Adult; Anthelmintics; Blood Chemical Analysis; Child; Collateral Circulation; Electroencephalography; Female; Humans; Imidazoles; Liver; Liver Diseases; Liver Function Tests; Male; Middle Aged; Portography; Psychoses, Substance-Induced; Schistosomiasis; Seizures; Splenic Diseases; Thiazoles | 1969 |
Toxicity of the levo form of tetramisole in Angora goats.
Topics: Administration, Oral; Animals; Body Weight; Drug Tolerance; Goats; Imidazoles; Neurologic Manifestations; Poisoning; Seizures; Species Specificity; Thiazoles | 1971 |