benzamidine has been researched along with Seizures in 1 studies
benzamidine: RN given refers to parent cpd
benzamidine : A carboxamidine that is benzene carrying an amidino group.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Five bis-benzamidines were screened towards murine magnesium deficiency-dependent audiogenic seizures, unravelling two compounds with efficacious doses 50 (ED(50)) less than 10mg/kg." | 3.76 | 1,2-ethane bis-1-amino-4-benzamidine is active against several brain insult and seizure challenges through anti-NMDA mechanisms targeting the 3H-TCP binding site and antioxidant action. ( Bac, P; Gressens, P; Maurois, P; Pages, N; Stables, JP; Stanicki, D; Vamecq, J; Vanden Eynde, JJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vamecq, J | 1 |
| Maurois, P | 1 |
| Pages, N | 1 |
| Bac, P | 1 |
| Stables, JP | 1 |
| Gressens, P | 1 |
| Stanicki, D | 1 |
| Vanden Eynde, JJ | 1 |
1 other study available for benzamidine and Seizures
| Article | Year |
|---|---|
1,2-ethane bis-1-amino-4-benzamidine is active against several brain insult and seizure challenges through anti-NMDA mechanisms targeting the 3H-TCP binding site and antioxidant action.
Topics: Animals; Anticonvulsants; Antioxidants; Benzamidines; Binding Sites; Body Temperature; Brain; Mice; | 2010 |