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pargyline and Seizures

pargyline has been researched along with Seizures in 20 studies

Pargyline: A monoamine oxidase inhibitor with antihypertensive properties.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
" The effects of some noradrenergic agents on seizures induced by strychnine were investigated in mice."7.69Strychnine-induced seizures in mice: the role of noradrenaline. ( Amabeoku, G; Chandomba, R, 1994)
"The effects of some noradrenergic agents, phenobarbitone, diazepam and phenytoin on seizures produced by propranolol were investigated in mice."7.69Propranolol-induced seizures in mice: the role of noradrenaline. ( Amabeoku, GJ; Syce, JA, 1997)
"The influence of some noradrenergic, 5-hydroxytryptaminergic and cholinergic agents on imipramine-induced seizures were investigated in mice."7.68The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice. ( Amabeoku, GJ, 1993)
" The effects of some noradrenergic agents on seizures induced by strychnine were investigated in mice."3.69Strychnine-induced seizures in mice: the role of noradrenaline. ( Amabeoku, G; Chandomba, R, 1994)
"The effects of some noradrenergic agents, phenobarbitone, diazepam and phenytoin on seizures produced by propranolol were investigated in mice."3.69Propranolol-induced seizures in mice: the role of noradrenaline. ( Amabeoku, GJ; Syce, JA, 1997)
"The influence of some noradrenergic, 5-hydroxytryptaminergic and cholinergic agents on imipramine-induced seizures were investigated in mice."3.68The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice. ( Amabeoku, GJ, 1993)
"The effects of the chronic administration of antidepressants on threshold electroconvulsive (ECS) seizures were evaluated in rats."1.27Chronic but not acute treatment with antidepressants enhances the electroconvulsive seizure response in rats. ( Peterson, SL; St Mary, JS; Trzeciakowski, JP, 1985)
" In the present study we determined the time-course and dose-response effects of 6-MeO-THbetaC for blockade of AGS."1.26Effects of 6-methoxy-1,2,3,4-tetrahydro-beta-carboline (6-MeO-THbetaC) on audiogenic seizures in DBA/2J mice. ( Buckholtz, NS; Sparks, DL, 1980)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199017 (85.00)18.7374
1990's3 (15.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
LESSIN, AW1
LONG, RF1
PARKES, MW1
Wiklund, L1
Sjölund, B1
Björklund, A1
Sparks, DL1
Buckholtz, NS1
Philo, R1
Amabeoku, G1
Chandomba, R1
Amabeoku, GJ2
Syce, JA1
Wilkison, DM1
Halpern, LM1
Herrera, HH1
Morgan, WW1
Reiter, RJ1
Rogers, ME1
Sam, J1
Peterson, SL1
Trzeciakowski, JP1
St Mary, JS1
Wallach, MB1
Winters, WD1
Mandell, AJ1
Spooner, CE1
Peters, DA1
Hrdina, PD1
Singhal, RL1
Ling, GM1
Diaz, PM1
Boissier, JR1
Simon, P1
Villeneuve, A1
Larousse, C1
Turner, TA1
Spencer, PS1
McKenzie, GM1
Soroko, FE1
Schatz, RA1
Lal, H1
Weissman, A1
Koe, BK1
Foster, LL1
Scott, WN1

Other Studies

20 other studies available for pargyline and Seizures

ArticleYear
CENTRAL STIMULANT ACTIONS OF ALPHA-ALKYL SUBSTITUTED TRYPTAMINES IN MICE.
    British journal of pharmacology and chemotherapy, 1965, Volume: 24

    Topics: Body Temperature; Brain; Carboxy-Lyases; Central Nervous System Stimulants; Indoles; Injections, Int

1965
Morphological and functional studies on the serotoninergic innervation of the inferior olive.
    Journal de physiologie, 1981, Volume: 77, Issue:2-3

    Topics: 5,6-Dihydroxytryptamine; 5,7-Dihydroxytryptamine; Action Potentials; Afferent Pathways; Animals; Aut

1981
Effects of 6-methoxy-1,2,3,4-tetrahydro-beta-carboline (6-MeO-THbetaC) on audiogenic seizures in DBA/2J mice.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:1

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Benzofurans; Carbolines; Citalopram; Clomipramin

1980
Catecholamines and pinealectomy-induced convulsions in the gerbil (Meriones unguiculatus).
    Progress in clinical and biological research, 1982, Volume: 92

    Topics: alpha-Methyltyrosine; Animals; Brain; Catecholamines; Dopamine; Gerbillinae; Levodopa; Male; Methylt

1982
Strychnine-induced seizures in mice: the role of noradrenaline.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Disulfiram; Droxidopa; Idazoxan; Imipram

1994
The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice.
    Experientia, 1993, Oct-15, Volume: 49, Issue:10

    Topics: 5-Hydroxytryptophan; Acetylcholine; alpha-Methyltyrosine; Animals; Atropine; Clonidine; Dioxanes; Dr

1993
Propranolol-induced seizures in mice: the role of noradrenaline.
    Cellular and molecular life sciences : CMLS, 1997, Volume: 53, Issue:8

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic Uptake Inhibitors; alpha-Methyltyros

1997
The role of biogenic amines in amygdalar kindling. I. Local amygdalar afterdischarge.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 211, Issue:1

    Topics: Action Potentials; Amygdala; Animals; Biogenic Amines; Electric Stimulation; Fenclonine; Male; Methy

1979
Brain norepinephrine levels in parathyroidectomized rats induced to convulse by pinealectomy.
    Experimental neurology, 1975, Volume: 48, Issue:3 Pt 1

    Topics: Animals; Brain; Dopamine; Male; Norepinephrine; Parathyroid Glands; Pargyline; Pineal Gland; Postope

1975
3-Arylquinolizidines, potential antidepressant agents.
    Journal of medicinal chemistry, 1975, Volume: 18, Issue:11

    Topics: Acoustic Stimulation; Animals; Antidepressive Agents; Dihydroxyphenylalanine; Lethal Dose 50; Mice;

1975
Chronic but not acute treatment with antidepressants enhances the electroconvulsive seizure response in rats.
    Neuropharmacology, 1985, Volume: 24, Issue:10

    Topics: Amoxapine; Animals; Antidepressive Agents; Clomipramine; Convulsants; Desipramine; Electric Stimulat

1985
A correlation of EEG, reticular multiple unit activity and gross behavior following various antidepressant agents in the cat. IV.
    Electroencephalography and clinical neurophysiology, 1969, Volume: 27, Issue:6

    Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Cats; Chlorpromazine; Desipramine;

1969
The role of brain serotonin in DDT-induced hyperpyrexia.
    Journal of neurochemistry, 1972, Volume: 19, Issue:4

    Topics: Animals; Brain; Brain Stem; DDT; Fenclonine; Fever; Fluorine; Hydroxyindoleacetic Acid; Male; Pargyl

1972
Interaction of pentylenetetrazol and trimethadione on the metabolism of serotonin in brain and its relation to the anticonvulsant action of trimethadione.
    Neuropharmacology, 1974, Volume: 13, Issue:7

    Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Brain; Brain Chemistry; Dose-Response Relationship, D

1974
Flurothyl in mice: seizure, post-convulsive behavior, and interactions with psychotropic drugs.
    Canadian journal of physiology and pharmacology, 1968, Volume: 46, Issue:1

    Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Biperiden; Caffeine; Catalepsy; Central Nervous Sy

1968
Effect of pretreatment with monoamine oxidase inhibitors or (+)-amphetamine on leptazol convulsions in mice and rats.
    The Journal of pharmacy and pharmacology, 1968, Volume: 20

    Topics: Amphetamine; Animals; Iproniazid; Male; Mice; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Pe

1968
The effects of apomorphine, (+)-amphetamine and L-dopa on maximal electroshock convulsions--a comparative study in the rat and mouse.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:9

    Topics: Amphetamine; Animals; Apomorphine; Dextroamphetamine; Dihydroxyphenylalanine; Electroshock; Lethal D

1972
Elevation of brain GABA by pargyline: a possible mechanism for protection against oxygen toxicity.
    Journal of neurochemistry, 1971, Volume: 18, Issue:12

    Topics: Aminobutyrates; Animals; Brain; Brain Chemistry; Hyperbaric Oxygenation; Male; Mice; Mice, Inbred St

1971
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxid

1967
Observations on the effects of decaborane and several potential antidotes in the rat. SAM-TR-67-103.
    [Technical report] SAM-TR. USAF School of Aerospace Medicine, 1967

    Topics: Animals; Antidotes; Ataxia; Boron Compounds; Male; Methanol; Pargyline; Picolines; Pyridoxine; Rats;

1967