Page last updated: 2024-12-07
5'-deoxytoyocamycin
Description
5'-deoxytoyocamycin: from Streptomyces sp. A14345; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
PubMed CID | 128252 |
CHEMBL ID | 99388 |
SCHEMBL ID | 6877410 |
MeSH ID | M0192044 |
Synonyms (12)
Synonym |
CHEMBL99388 , |
5'-deoxytoyocamycin |
4-amino-7-(3,4-dihydroxy-5-methyl-tetrahydro-furan-2-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
4-amino-7-((2r,3r,4s,5r)-3,4-dihydroxy-5-methyl-tetrahydro-furan-2-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
4-amino-7-((2r,3r,4s,5r)-3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
bdbm50090861 |
65562-55-2 |
4-amino-7-[(2r,3r,4s,5r)-3,4-dihydroxy-5-methyloxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
7h-pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-amino-7-(5-deoxy-beta-d-ribofuranosyl)- |
SCHEMBL6877410 |
DTXSID60984150 |
4-amino-7-(5-deoxypentofuranosyl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
Protein Targets (1)
Inhibition Measurements
Biological Processes (7)
Molecular Functions (5)
Ceullar Components (4)
Bioassays (4)
Assay ID | Title | Year | Journal | Article |
AID382097 | Inhibition of adenosine kinase | 2008 | Bioorganic & medicinal chemistry, May-01, Volume: 16, Issue:9
| A CoMSIA study on the adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues. |
AID33993 | Inhibition concentration against human adenosine kinase | 2002 | Bioorganic & medicinal chemistry letters, Mar-25, Volume: 12, Issue:6
| QSAR study on adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues using the hansch approach. |
AID33985 | Inhibition of recombinant human adenosine kinase | 2000 | Journal of medicinal chemistry, Jul-27, Volume: 43, Issue:15
| Adenosine kinase inhibitors. 1. Synthesis, enzyme inhibition, and antiseizure activity of 5-iodotubercidin analogues. |
AID33990 | Inhibition of human adenosine kinase activity | 2002 | Bioorganic & medicinal chemistry letters, Mar-25, Volume: 12, Issue:6
| QSAR study on adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues using the hansch approach. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (5)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (20.00) | 18.2507 |
2000's | 3 (60.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.58
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 12.58 (24.57) | Research Supply Index | 1.79 (2.92) | Research Growth Index | 4.37 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |