Page last updated: 2024-12-07
5'-deoxytoyocamycin
Description
5'-deoxytoyocamycin: from Streptomyces sp. A14345; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 128252 |
| CHEMBL ID | 99388 |
| SCHEMBL ID | 6877410 |
| MeSH ID | M0192044 |
Synonyms (12)
| Synonym |
|---|
| CHEMBL99388 , |
| 5'-deoxytoyocamycin |
| 4-amino-7-(3,4-dihydroxy-5-methyl-tetrahydro-furan-2-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
| 4-amino-7-((2r,3r,4s,5r)-3,4-dihydroxy-5-methyl-tetrahydro-furan-2-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
| 4-amino-7-((2r,3r,4s,5r)-3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
| bdbm50090861 |
| 65562-55-2 |
| 4-amino-7-[(2r,3r,4s,5r)-3,4-dihydroxy-5-methyloxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
| 7h-pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-amino-7-(5-deoxy-beta-d-ribofuranosyl)- |
| SCHEMBL6877410 |
| DTXSID60984150 |
| 4-amino-7-(5-deoxypentofuranosyl)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
Protein Targets (1)
Inhibition Measurements
Biological Processes (7)
Molecular Functions (5)
Ceullar Components (4)
Bioassays (4)
| Assay ID | Title | Year | Journal | Article |
|---|
| AID382097 | Inhibition of adenosine kinase | 2008 | Bioorganic & medicinal chemistry, May-01, Volume: 16, Issue:9
| A CoMSIA study on the adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues. |
| AID33993 | Inhibition concentration against human adenosine kinase | 2002 | Bioorganic & medicinal chemistry letters, Mar-25, Volume: 12, Issue:6
| QSAR study on adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues using the hansch approach. |
| AID33985 | Inhibition of recombinant human adenosine kinase | 2000 | Journal of medicinal chemistry, Jul-27, Volume: 43, Issue:15
| Adenosine kinase inhibitors. 1. Synthesis, enzyme inhibition, and antiseizure activity of 5-iodotubercidin analogues. |
| AID33990 | Inhibition of human adenosine kinase activity | 2002 | Bioorganic & medicinal chemistry letters, Mar-25, Volume: 12, Issue:6
| QSAR study on adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues using the hansch approach. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.58
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.58 (24.57) | | Research Supply Index | 1.79 (2.92) | | Research Growth Index | 4.37 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |