Page last updated: 2024-08-26

imipenem, anhydrous and Seizures

imipenem, anhydrous has been researched along with Seizures in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (20.75)	18.7374
1990's	24 (45.28)	18.2507
2000's	11 (20.75)	29.6817
2010's	6 (11.32)	24.3611
2020's	1 (1.89)	2.80

Authors

Authors	Studies
Bermingham, A; Blais, J; Capka, V; Cariaga, T; Casarez, A; Colvin, R; Dean, CR; Fekete, A; Gong, W; Growcott, E; Guo, H; Jones, AK; Li, C; Li, F; Lin, X; Lindvall, M; Lopez, S; McKenney, D; Metzger, L; Moser, HE; Prathapam, R; Rasper, D; Reck, F; Rudewicz, P; Sethuraman, V; Shaul, J; Shen, X; Simmons, RL; Tang, D; Tashiro, K; Tjandra, M; Turner, N; Uehara, T; Vitt, C; Whitebread, S; Yifru, A; Zang, X; Zhu, Q	1
Caroline, C; Chien-Boon Lye, D; Choon-Kiat Tan, N; Ding, YY; Hsien-Xiong Lee, R; Lim, JP; Neo, HY; Pei-Ying Ho, E; Tan, KT; Wei-Han Ng, D	1
Benjamin, DK; Capparelli, EV; Clark, RH; Cohen-Wolkowiez, M; Herring, AH; Hornik, CP; Kearns, GL; Smith, PB; van den Anker, J	1
Cannon, JP; Clark, NM; Grim, SA; Lee, TA; Setlak, P	1
Chen, K; Shi, Z; Wang, Q; Wu, Y	1
Rüegg, S; Sutter, R; Tschudin-Sutter, S	1
Galante, D	1
Arnold, HM; Augustin, KM; Casabar, E; Dubberke, ER; Hladnik, LM; McKinnon, PS; Reichley, RM; Ritchie, DJ; Westervelt, P	1
Kurata, Y; Kurosawa, T; Nawa, T; Shibasaki, S; Suzuki, H; Yagi, Y	1
Barsaoui, S; Ben Jaballah, N; Bousnina, S; Bouziri, A; Hajji, N; Hariga, D; Kechrid, A; Sammoud, A; Smaoui, H	1
Fukuda, H; Kawamura, Y	1
Lovic, OS; Susic, V; Zivanovic, D	1
Stanojlovic, O; Stojanovic, J; Susic, V; Zivanovic, D	2
Ammendola, D; De Sarro, A; De Sarro, G; Nava, F	1
Day, IP; Goudie, J; Nishiki, K; Williams, PD	1
Matsumura, H; Nouda, H; Sumita, Y; Sunagawa, M	1
Ammendola, D; De Sarro, A; De Sarro, G	1
Caldwell, JW; Fink, MP; Heard, SO; Johnson, RH; Leeper, KV; Niederman, MS; Schentag, JJ; Siami, GA; Snydman, DR; Wunderink, RG	1
Burke, JP; Classen, DC; Evans, RS; Pestotnik, SL; Stevens, LE	1
Bianchi Llave, JL; Duro Ruiz, G; López-Gómez, M; Mediavilla García, JD	1
Kania, D; Lane, M; Rapp, RP	1
Guglielmo, BJ; Jacobs, RA	1
Norrby, SR	2
Campise, M	1
Schranz, J	1
Imamura, H; Jona, H; Kiyonaga, H; Moriya, M; Nakagawa, S; Nakano, M; Ohtake, N; Sato, H; Shimizu, A; Ushijima, R	1
Hunter, WJ	1
Gildon, KM; Norrby, SR	1
Cho, JH; Jin, C; Jung, I; Kim, DH; Kim, M; Ku, HJ; Oh, CH; Yook, J	1
Turhal, NS	1
Bouquet, S; Couet, W; Dupuis, A; Limosin, A; Mimoz, O; Paquereau, J	1
Salaria, M	1
Daras, M; Hauser, WA; Koppel, BS; Politis, C; van Duin, D	1
Fukasawa, M; Matsumura, H; Sunagawa, M	1
Hill, EM; McCarthy, ID; Mostow, SR; Newcomb, HW	1
Allen, N; Semel, JD	1
Ballow, CH; Leo, RJ	1
Inderlied, CB; Kim, KS; Mason, WH; Ross, LA; Wong, VK; Wright, HT	1
Dretler, RH; Job, ML	1
Brown, RB; Morris, AB; Sands, M	1
Chmel, H; Eng, RH; Munsif, AN; Smith, SM; Yangco, BG	1
Eguchi, T; Fujishita, M; Kataoka, R; Kotani, S; Miyagi, T; Miyoshi, I; Taguchi, H; Takeuchi, T	1
Giles, RE; Patel, JB	1
Haruta, T; Kobayashi, Y; Kubo, K; Kuroki, S; Okura, KE; Yamamoto, H; Yamaoka, K	1
May, G	1
Schliamser, SE	1
Calandra, G; Carrigan, J; Guess, H; Lydick, E; Weiss, L	1
Bennett, DB; Comereski, CR; Williams, PD	1
Park, SY; Parker, RH	1
Ahonkhai, VI; Aziz, MA; Brown, KR; Calandra, GB; Grad, LC; Wang, C	1
Alexander, JW; Fant, WK; Rivera, JO; Solomkin, JS	1

Reviews

8 review(s) available for imipenem, anhydrous and Seizures

Article	Year
The risk of seizures among the carbapenems: a meta-analysis. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:8 Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Child; Cilastatin; Cilastatin, Imipenem Drug Combination; Doripenem; Drug Combinations; Ertapenem; Humans; Imipenem; Meropenem; Risk; Seizures; Thienamycins	2014
Seizures as adverse events of antibiotic drugs: A systematic review. Neurology, 2015, Oct-13, Volume: 85, Issue:15 Topics: Animals; Anti-Bacterial Agents; Central Nervous System; Cephalosporins; Humans; Imipenem; Risk; Seizures	2015
Neurotoxicity of carbapenem antibacterials. Drug safety, 1996, Volume: 15, Issue:2 Topics: Animals; Carbapenems; Child; Cilastatin; Humans; Imipenem; Meropenem; Receptors, GABA; Seizures; Thienamycins	1996
Safety profile of meropenem: a review of nearly 5,000 patients treated with meropenem. Scandinavian journal of infectious diseases, 1999, Volume: 31, Issue:1 Topics: Adult; Anti-Bacterial Agents; Cephalosporins; Child; Child, Preschool; Clindamycin; Diarrhea; Drug Eruptions; Humans; Imipenem; Meningitis; Meropenem; Nausea; Seizures; Thienamycins; Thrombocytosis	1999
Carbapenems in serious infections: a risk-benefit assessment. Drug safety, 2000, Volume: 22, Issue:3 Topics: Adult; Cephalosporins; Child; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Tolerance; Humans; Imipenem; Meningitis, Bacterial; Meropenem; Risk Assessment; Seizures; Thienamycins	2000
Imipenem. Indian pediatrics, 2001, Volume: 38, Issue:12 Topics: Adolescent; Child; Child, Preschool; Cross Infection; Exanthema; Humans; Imipenem; Infant; Seizures; Thienamycins	2001
Topics in clinical pharmacology: imipenem, a new broad spectrum antibiotic. The American journal of the medical sciences, 1988, Volume: 296, Issue:4 Topics: Humans; Imipenem; Seizures	1988
Review of imipenem. Infection control : IC, 1986, Volume: 7, Issue:6 Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Imipenem; Seizures; Thienamycins	1986

Trials

5 trial(s) available for imipenem, anhydrous and Seizures

Article	Year
Treatment of severe pneumonia in hospitalized patients: results of a multicenter, randomized, double-blind trial comparing intravenous ciprofloxacin with imipenem-cilastatin. The Severe Pneumonia Study Group. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:3 Topics: Adult; Aged; Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Double-Blind Method; Drug Combinations; Drug Resistance, Microbial; Female; Hospitalization; Humans; Imipenem; Injections, Intravenous; Male; Middle Aged; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Regression Analysis; Seizures	1994
Imipenem/cilastatin treatment of bacterial meningitis in children. The Pediatric infectious disease journal, 1991, Volume: 10, Issue:2 Topics: Anti-Bacterial Agents; Bacterial Infections; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Infant; Male; Meningitis; Meningitis, Haemophilus; Meningitis, Meningococcal; Retrospective Studies; Seizures	1991
Seizure propensity with imipenem. Archives of internal medicine, 1989, Volume: 149, Issue:8 Topics: Aged; Aged, 80 and over; Animals; Cefotaxime; Female; Humans; Imipenem; Male; Mice; Middle Aged; Multicenter Studies as Topic; Penicillin G; Seizures	1989
Factors predisposing to seizures in seriously ill infected patients receiving antibiotics: experience with imipenem/cilastatin. The American journal of medicine, 1988, Volume: 84, Issue:5 Topics: Anti-Bacterial Agents; Bacterial Infections; Body Weight; Central Nervous System Diseases; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Kidney Function Tests; Male; Regression Analysis; Retrospective Studies; Risk Factors; Seizures; Thienamycins; Time Factors; United States	1988
Randomized trial of imipenem/cilastatin versus gentamicin and clindamycin in mixed flora infections. The American journal of medicine, 1985, Jun-07, Volume: 78, Issue:6A Topics: Adult; Aged; Bacterial Infections; Cilastatin; Clindamycin; Clinical Trials as Topic; Creatinine; Cyclopropanes; Drug Combinations; Female; Gentamicins; Humans; Imipenem; Male; Middle Aged; Random Allocation; Seizures; Thienamycins	1985

Other Studies

40 other study(ies) available for imipenem, anhydrous and Seizures

Article	Year
Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228. Bioorganic & medicinal chemistry letters, 2018, 02-15, Volume: 28, Issue:4 Topics: Animals; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; CHO Cells; Cricetulus; Drug Stability; Escherichia coli; Female; Humans; Meropenem; Mice; Microbial Sensitivity Tests; Molecular Structure; Monobactams; Pseudomonas aeruginosa; Receptors, GABA-A; Seizures; Structure-Activity Relationship; Thienamycins	2018
Higher rates of carbapenem-related seizures in older hospitalised adults. Internal medicine journal, 2020, Volume: 50, Issue:1 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Ertapenem; Female; Hospitalization; Humans; Imipenem; Logistic Models; Male; Meropenem; Seizures; Singapore	2020
Adverse events associated with meropenem versus imipenem/cilastatin therapy in a large retrospective cohort of hospitalized infants. The Pediatric infectious disease journal, 2013, Volume: 32, Issue:7 Topics: Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Cohort Studies; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Humans; Imipenem; Incidence; Infant; Intensive Care, Neonatal; Meropenem; Retrospective Studies; Seizures; Survival Analysis; Thienamycins	2013
A Retrospective Study on the Incidence of Seizures among Neurosurgical Patients Who Treated with Imipenem/Cilastatin or Meropenem. Current pharmaceutical biotechnology, 2014, Volume: 15, Issue:8 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Incidence; Male; Meropenem; Middle Aged; Retrospective Studies; Seizures; Thienamycins; Young Adult	2014
An unusual cause of seizures during subarachnoid anesthesia in a patient undergoing transurethral resection of the prostate: a case report. Minerva anestesiologica, 2009, Volume: 75, Issue:4 Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cilastatin; Diagnosis, Differential; Humans; Imipenem; Intraoperative Complications; Male; Preanesthetic Medication; Prostatic Hyperplasia; Seizures; Subarachnoid Space; Transurethral Resection of Prostate	2009
Assessment of an alternative meropenem dosing strategy compared with imipenem-cilastatin or traditional meropenem dosing after cefepime failure or intolerance in adults with neutropenic fever. Pharmacotherapy, 2009, Volume: 29, Issue:8 Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cilastatin; Cilastatin, Imipenem Drug Combination; Cohort Studies; Dose-Response Relationship, Drug; Drug Combinations; Female; Fever; Hospital Mortality; Humans; Imipenem; Male; Meropenem; Middle Aged; Neutropenia; Retreatment; Seizures; Thienamycins; Time Factors	2009
[Convulsive liability of an oral carbapenem antibiotic, tebipenem pivoxil]. The Japanese journal of antibiotics, 2009, Volume: 62, Issue:3 Topics: Administration, Oral; Animals; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Imipenem; Infusions, Intravenous; Injections, Intraventricular; Male; Mice; Pentylenetetrazole; Rats; Seizures	2009
[Iatrogenic meningitis after diagnosis lumbar puncture: 3 cases reports in the paediatric Children's Hospital of Tunis]. Bulletin de la Societe de pathologie exotique (1990), 2011, Volume: 104, Issue:1 Topics: beta-Lactam Resistance; Brain Abscess; Brain Damage, Chronic; Ciprofloxacin; Drug Therapy, Combination; Enterobacter cloacae; Enterobacteriaceae Infections; Female; Fosfomycin; Humans; Hydrocephalus; Iatrogenic Disease; Imipenem; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Klebsiella Infections; Klebsiella pneumoniae; Male; Meningitis, Bacterial; Muscle Hypotonia; Seizures; Serratia Infections; Serratia marcescens; Spinal Puncture; Subdural Effusion; Tunisia	2011
[Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:3 Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; beta-Alanine; Biphenyl Compounds; Cefazolin; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Convulsants; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Imipenem; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Norfloxacin; Oxazines; Penicillin G; Quinolones; Seizures; Thienamycins	2002
Effects of manipulation of N-methyl-D-aspartate receptors on imipenem/cilastatin-induced seizures in rats. The Indian journal of medical research, 2004, Volume: 119, Issue:2 Topics: Acetamides; Animals; Binding Sites; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Electroencephalography; Imipenem; Male; Pyrrolidinones; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Valine	2004
Induction of audiogenic seizures in imipenem/cilastatin-treated rats. Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:2 Topics: Animals; Anti-Bacterial Agents; Brain; Cilastatin; Dipeptidases; Drug Therapy, Combination; Electroencephalography; Imipenem; Injections, Intraventricular; Male; Motor Activity; Rats; Rats, Wistar; Seizures; Signal Processing, Computer-Assisted	2004
The effects of phenytoin and phenobarbital on seizures induced by imipenem/cilastatin in rats. Acta neurologica Belgica, 2004, Volume: 104, Issue:1 Topics: Animals; Anticonvulsants; Cilastatin; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Imipenem; Injections, Intraventricular; Male; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Wistar; Seizures	2004
Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice. Brain research, 1995, Feb-06, Volume: 671, Issue:1 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Anticonvulsants; Dizocilpine Maleate; Excitatory Amino Acids; Glutamine; Imipenem; Kynurenic Acid; Mice; Mice, Inbred DBA; Muscimol; Piperazines; Piperidines; Quinoxalines; Seizures	1995
Correlation between in vitro and in vivo models of proconvulsive activity with the carbapenem antibiotics, biapenem, imipenem/cilastatin and meropenem. Toxicology letters, 1995, Volume: 76, Issue:3 Topics: Analysis of Variance; Animals; Binding, Competitive; Cilastatin; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Imipenem; Injections, Intravenous; Male; Meropenem; Mice; Muscimol; Pentylenetetrazole; Rats; Receptors, GABA-A; Seizures; Thienamycins	1995
Structural features resulting in convulsive activity of carbapenem compounds: effect of C-2 side chain. The Journal of antibiotics, 1995, Volume: 48, Issue:5 Topics: Animals; Imipenem; Meropenem; Mice; Mice, Inbred ICR; Receptors, GABA; Seizures; Structure-Activity Relationship; Thienamycins	1995
Effects of some quinolones on imipenem-induced seizures in DBA/2 mice. General pharmacology, 1994, Volume: 25, Issue:2 Topics: Acoustic Stimulation; Animals; Anti-Infective Agents; Drug Interactions; Electrocardiography; Imipenem; Injections, Intravenous; Lipids; Mice; Mice, Inbred DBA; Molecular Weight; Nalidixic Acid; Seizures; Species Specificity; Structure-Activity Relationship	1994
Prospective surveillance of imipenem/cilastatin use and associated seizures using a hospital information system. The Annals of pharmacotherapy, 1993, Volume: 27, Issue:4 Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Algorithms; Child; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Pharmacy Information Systems; Drug Combinations; Female; Hospital Bed Capacity, 500 and over; Hospitals, University; Humans; Imipenem; Incidence; Length of Stay; Male; Middle Aged; Patient Admission; Population Surveillance; Prospective Studies; Seizures; Utah	1993
[Convulsions induced by imipenem in an HIV-positive patient]. Enfermedades infecciosas y microbiologia clinica, 1995, Volume: 13, Issue:9 Topics: Adult; Female; HIV Seropositivity; Humans; Imipenem; Otitis Media, Suppurative; Pseudomonas Infections; Seizures; Thienamycins	1995
Seizures related to use of imipenem-cilastatin. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Jul-01, Volume: 53, Issue:13 Topics: Adult; Aged; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Humans; Imipenem; Male; Middle Aged; Risk Factors; Seizures	1996
Impact of dosage-monitoring system on frequency of seizures associated with imipenem-cilastatin. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Sep-01, Volume: 53, Issue:17 Topics: Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Delivery Systems; Drug Monitoring; Drug Therapy, Combination; Humans; Imipenem; Risk Factors; Seizures	1996
Neurological complication during imipenem/cilastatin therapy in uraemic patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:7 Topics: Aged; Aged, 80 and over; Cilastatin; Confusion; Female; Humans; Imipenem; Male; Middle Aged; Nervous System; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Protease Inhibitors; Seizures; Thienamycins; Tremor; Uremia	1998
Comparisons of seizure incidence and adverse experiences between imipenem and meropenem. Critical care medicine, 1998, Volume: 26, Issue:8 Topics: Animals; Drug Approval; Humans; Imipenem; Incidence; Meropenem; Seizures; Thienamycins; United States; United States Food and Drug Administration	1998
Novel dithiocarbamate carbapenems with anti-MRSA activity. Bioorganic & medicinal chemistry, 1998, Volume: 6, Issue:7 Topics: Animals; Bacterial Proteins; Blood Proteins; Carbapenems; Carrier Proteins; Colony Count, Microbial; Dipeptidases; Hexosyltransferases; Humans; Imipenem; Kidney; Male; Methicillin Resistance; Mice; Mice, Inbred ICR; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Protein Binding; Rats; Seizures; Staphylococcus aureus; Structure-Activity Relationship; Swine; Thienamycins	1998
Imipenem-induced seizure: a case of inappropriate, excessive, and prolonged surgical prophylaxis. Hospital pharmacy, 1993, Volume: 28, Issue:10 Topics: Aged; Drug Utilization Review; Humans; Imipenem; Male; Pharmacy Service, Hospital; Seizures; South Carolina	1993
Low convulsive activity of a new carbapenem antibiotic, DK-35C, as compared with existing congeners. Toxicology, 1999, Nov-05, Volume: 138, Issue:2 Topics: Animals; Carbapenems; Cefazolin; Cephalosporins; GABA Agonists; Imipenem; Injections, Intraventricular; Male; Meropenem; Mice; Mice, Inbred ICR; Muscimol; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Synaptic Membranes; Thienamycins	1999
Cyclosporin A and imipenem associated seizure activity in allogeneic bone marrow transplantation patients. Journal of chemotherapy (Florence, Italy), 1999, Volume: 11, Issue:5 Topics: Adult; Bone Marrow Transplantation; Cyclosporine; Female; Humans; Imipenem; Immunosuppressive Agents; Male; Middle Aged; Postoperative Complications; Seizures	1999
Pharmacokinetic-pharmacodynamic modeling of electroencephalogram effect of imipenem in rats with acute renal failure. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:12 Topics: Acute Kidney Injury; Animals; Electroencephalography; Imipenem; Kidney Function Tests; Male; Models, Biological; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Seizures; Thienamycins	2001
Seizures in the critically ill: the role of imipenem. Epilepsia, 2001, Volume: 42, Issue:12 Topics: Acute Disease; Anti-Bacterial Agents; Critical Illness; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Hospital Records; Hospitalization; Humans; Imipenem; Incidence; Life Tables; Risk Factors; Seizures; Treatment Outcome	2001
Structure-activity relationships of carbapenem and penem compounds for the convulsive property. The Journal of antibiotics, 1992, Volume: 45, Issue:12 Topics: Animals; Anti-Bacterial Agents; Brain; Imipenem; Incidence; Injections, Intraventricular; Meropenem; Mice; Seizures; Structure-Activity Relationship; Thienamycins	1992
Imipenem-cilastatin dosing intervention program by pharmacists. American journal of hospital pharmacy, 1992, Volume: 49, Issue:5 Topics: Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Colorado; Drug Combinations; Hospital Bed Capacity, 300 to 499; Humans; Imipenem; Medication Errors; Pharmacists; Pharmacy Service, Hospital; Program Evaluation; Retrospective Studies; Risk Factors; Seizures	1992
Seizures in patients simultaneously receiving theophylline and imipenem or ciprofloxacin or metronidazole. Southern medical journal, 1991, Volume: 84, Issue:4 Topics: Aged; Ciprofloxacin; Drug Interactions; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Imipenem; Male; Metronidazole; Middle Aged; Monitoring, Physiologic; Seizures; Theophylline	1991
Seizure activity associated with imipenem use: clinical case reports and review of the literature. DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:4 Topics: Aged; Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Seizures	1991
Seizure activity with imipenem therapy: incidence and risk factors. DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:5 Topics: Aged; Aged, 80 and over; Bacterial Infections; Humans; Imipenem; Joint Diseases; Knee Joint; Male; Pneumonia; Risk Factors; Seizures	1990
Seizure propensity with imipenem. Archives of internal medicine, 1990, Volume: 150, Issue:7 Topics: Cilastatin; Cilastatin, Imipenem Drug Combination; Creatinine; Drug Administration Schedule; Drug Combinations; Humans; Imipenem; Seizures	1990
[Seizure and tremor occurring in acute leukemia patients treated with imipenem/cilastatin]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:3 Topics: Acute Disease; Adult; Aged; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Leukemia; Middle Aged; Seizures; Tremor	1989
Meropenem: evidence of lack of proconvulsive tendency in mice. The Journal of antimicrobial chemotherapy, 1989, Volume: 24 Suppl A Topics: Animals; Carbapenems; Cilastatin; Imipenem; Male; Meropenem; Mice; Seizures; Thienamycins	1989
[Fundamental and clinical evaluation of imipenem/cilastatin sodium in the field of pediatrics]. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:7 Topics: Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Drug Eruptions; Female; Humans; Imipenem; Infant; Infusions, Intravenous; Male; Seizures; Thienamycins	1986
Neurotoxicity of beta-lactam antibiotics. Experimental kinetic and neurophysiological studies. Scandinavian journal of infectious diseases. Supplementum, 1988, Volume: 55 Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Blood-Brain Barrier; Brain; Carbapenems; Cilastatin; Drug Interactions; Electroencephalography; Enterobacteriaceae Infections; Female; Hippocampus; Imipenem; Male; Meningitis; Penicillin G; Rabbits; Rats; Rats, Inbred Strains; Seizures; Thiopental; Tissue Distribution; Uremia	1988
Animal model for evaluating the convulsive liability of beta-lactam antibiotics. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:5 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Binding, Competitive; Cefazolin; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Disease Models, Animal; Drug Combinations; gamma-Aminobutyric Acid; Imipenem; Lactams; Male; Mice; Pentylenetetrazole; Seizures; Thienamycins	1988
Review of adverse experiences and tolerability in the first 2,516 patients treated with imipenem/cilastatin. The American journal of medicine, 1985, Jun-07, Volume: 78, Issue:6A Topics: Adolescent; Adult; Aged; Anaphylaxis; Cilastatin; Cyclopropanes; Digestive System; Drug Combinations; Drug Hypersensitivity; Humans; Imipenem; Liver; Middle Aged; Seizures; Thienamycins	1985