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dipyridamole and Seizures

dipyridamole has been researched along with Seizures in 9 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"One of the most dangerous aspects of theophylline toxicity is seizures."7.69Adenosine receptors are not involved in theophylline-induced seizures. ( Hornfeldt, CS; Larson, AA, 1994)
"Adenosine is a well-known endogenous modulator of neuronal excitability with anticonvulsant properties."5.42Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish. ( Bogo, MR; Bonan, CD; Capiotti, KM; da Costa Schaefer, I; Da Silva, RS; Frantz, JZ; Kist, LW; Menezes, FP; Siebel, AM, 2015)
"We induced generalized seizures by cortical injection of penicillin in anesthetized, paralyzed cats."5.28Role of endogenous adenosine in recurrent generalized seizures. ( Dowell, RT; Eldridge, FL; Paydarfar, D; Scott, SC, 1989)
"One of the most dangerous aspects of theophylline toxicity is seizures."3.69Adenosine receptors are not involved in theophylline-induced seizures. ( Hornfeldt, CS; Larson, AA, 1994)
"Epilepsy is characterized by the manifestation of spontaneous and recurrent seizures."1.91The Effect of Adenosine Signaling on Memory Impairment Induced by Pentylenetetrazole in Zebrafish. ( Bertoncello, KT; Bonan, CD, 2023)
"Adenosine is a well-known endogenous modulator of neuronal excitability with anticonvulsant properties."1.42Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish. ( Bogo, MR; Bonan, CD; Capiotti, KM; da Costa Schaefer, I; Da Silva, RS; Frantz, JZ; Kist, LW; Menezes, FP; Siebel, AM, 2015)
"A clinical diagnosis of thrombotic thrombocytopenic purpura (TTP) was made."1.30A case of dermatomyositis complicated by thrombotic thrombocytopenic purpura. ( Arase, S; Horie, T; Miyaoka, Y; Nameda, Y; Sano, N; Shigekiyo, T; Urano, Y, 1997)
"Pretreatment with adenosinergic agents and MK-801 markedly enhanced the protective effect of the stable analogs of adenosine namely, 2-chloroadenosine and N6-cyclohexyladenosine."1.28Effect of MK-801 and its interaction with adenosinergic agents and carbamazepine against hypoxic stress-induced convulsions and death in mice. ( Kulkarni, SK; Thorat, SN, 1990)
"We induced generalized seizures by cortical injection of penicillin in anesthetized, paralyzed cats."1.28Role of endogenous adenosine in recurrent generalized seizures. ( Dowell, RT; Eldridge, FL; Paydarfar, D; Scott, SC, 1989)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's4 (44.44)18.2507
2000's0 (0.00)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Bertoncello, KT1
Bonan, CD2
Socała, K1
Nieoczym, D1
Pieróg, M1
Wlaź, P1
Siebel, AM1
Menezes, FP1
Capiotti, KM1
Kist, LW1
da Costa Schaefer, I1
Frantz, JZ1
Bogo, MR1
Da Silva, RS1
Hornfeldt, CS1
Larson, AA1
Miyaoka, Y1
Urano, Y1
Nameda, Y1
Shigekiyo, T1
Horie, T1
Sano, N1
Arase, S1
Kulkarni, C1
David, J1
Joseph, T1
Thorat, SN1
Kulkarni, SK1
Morgan, PF1
Deckert, J1
Jacobson, KA1
Marangos, PJ1
Daly, JW1
Eldridge, FL1
Paydarfar, D1
Scott, SC1
Dowell, RT1

Other Studies

9 other studies available for dipyridamole and Seizures

ArticleYear
The Effect of Adenosine Signaling on Memory Impairment Induced by Pentylenetetrazole in Zebrafish.
    Neurochemical research, 2023, Volume: 48, Issue:6

    Topics: Adenosine; Animals; Dipyridamole; Epilepsy; Pentylenetetrazole; Quality of Life; Seizures; Valproic

2023
Role of the adenosine system and glucose restriction in the acute anticonvulsant effect of caprylic acid in the 6 Hz psychomotor seizure test in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2015, Mar-03, Volume: 57

    Topics: 3-Hydroxybutyric Acid; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonis

2015
Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish.
    Zebrafish, 2015, Volume: 12, Issue:2

    Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Diphosphate; Animals; Benzyl Compou

2015
Adenosine receptors are not involved in theophylline-induced seizures.
    Journal of toxicology. Clinical toxicology, 1994, Volume: 32, Issue:3

    Topics: Adenosine; Animals; Carbamazepine; Dipyridamole; Dose-Response Relationship, Drug; Injections, Intra

1994
A case of dermatomyositis complicated by thrombotic thrombocytopenic purpura.
    Dermatology (Basel, Switzerland), 1997, Volume: 194, Issue:1

    Topics: Anti-Inflammatory Agents; Dermatomyositis; Dipyridamole; Dyspnea; Epoprostenol; Fatal Outcome; Fever

1997
Influence of adenosine, dipyridamole, adenosine antagonists and antiepileptic drugs on EEG after discharge following cortical stimulation.
    Indian journal of experimental biology, 1997, Volume: 35, Issue:4

    Topics: Adenosine; Aminophylline; Animals; Anticonvulsants; Cerebral Cortex; Dipyridamole; Electric Stimulat

1997
Effect of MK-801 and its interaction with adenosinergic agents and carbamazepine against hypoxic stress-induced convulsions and death in mice.
    Methods and findings in experimental and clinical pharmacology, 1990, Volume: 12, Issue:9

    Topics: 2-Chloroadenosine; Adenosine; Animals; Carbamazepine; Dipyridamole; Dizocilpine Maleate; Drug Intera

1990
Potent convulsant actions of the adenosine receptor antagonist, xanthine amine congener (XAC).
    Life sciences, 1989, Volume: 45, Issue:8

    Topics: Animals; Caffeine; Convulsants; Diazepam; Dipyridamole; Male; Mice; Purinergic Antagonists; Random A

1989
Role of endogenous adenosine in recurrent generalized seizures.
    Experimental neurology, 1989, Volume: 103, Issue:2

    Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Cats; Cerebral Cortex; Dipyridamole; Doxapram; Nalo

1989