Page last updated: 2024-08-23

tramadol and Seizures

tramadol has been researched along with Seizures in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (7.81)	18.2507
2000's	13 (20.31)	29.6817
2010's	32 (50.00)	24.3611
2020's	14 (21.88)	2.80

Authors

Authors	Studies
Askari, M; Farrokhfall, K; Foadoddini, M; Mehrpour, O; Miri-Moghaddam, E; Nakhaee, S	1
Jeon, HL; Kim, JH; Lee, H; Park, S; Shin, JY	1
Adebowale, AA; Balogun, SA; Fawale, MB; Idowu, AO; Komolafe, MA; Sanusi, AA	1
Cisternino, S; Declèves, X; Malissin, I; Mégarbane, B; Pallet, N; Puszkiel, A	1
Chan, CK; Cheng, W; Lam, RPK	1
Lidetu, T; Zewdu, D	1
El-Bassyouni, GT; Elgohary, R; ElShebiney, SA; Hamzawy, EMA; Kenawy, SH	1
Abdelkawy, K; Abdeshafy, MM; Ali, AA; Elbarbry, F; Elsabaa, RM	1
Chawla, P; Raj, K; Singh, S	1
Ahmadi, AA; Asouri, M; Gholami, M; Nasirikenari, M; Rostamnezhad, M; Saboory, E	1
Ali, EI; Elfayomy, NM; Elmansy, AMM; Farrag, MA; Shamloul, RM	1
Ahmadiani, A; Asadi, S; Ershad, A; Savaheli, S; Sherafati, F; Sorayya, M; Valian, N	1
Bazmi, E; Behnoush, B; Khodakarim, S; Looha, MA; Nazari, SH; Soori, H	1
Amirabadizadeh, A; Askari, M; Brent, J; Farrokhfall, K; Foadoddini, M; Megarbane, B; Mehrpour, O; Miri-Moghaddam, E; Nakhaee, S	1
Chevillard, L; Indja, W; Lagard, C; Malissin, I; Mégarbane, B; Risède, P	1
Demirdjian, S; Dufour, C; Laplanche, A; Lemare, F; Maritaz, C; Valteau-Couanet, D	1
Ahmadimanesh, M; Ahsani Nasab, S; Ghazi-Khansari, M; Rouini, MR; Shadnia, S; Sheikholeslami, B	1
Dale, W; Danovitch, I; Hassamal, S; Miotto, K	1
Ashkezari, MD; Farahmand, B; Mohammadpour, A; Shokrzadeh, M	1
Chevillard, L; Lagard, C; Mégarbane, B	1
Mégarbane, B; Vodovar, D	1
Dormuth, CR; Gomes, T; Juurlink, DN; Mamdani, MM; Morrow, RL; Paterson, M	1
El-Nabarawy, NA; Gouda, AS; Mégarbane, B	1
Bryant, SM; Chhabra, N; Pallasch, EM; Wahl, M	1
Carpenter, JE; Dunkley, CA; Kazzi, Z; Moran, TP; Murray, BP	1
Ahangar, N; Bameri, B; Fallah, M; Mohammadi, H; Samadi, M; Shaki, F	1
Gholami, M; Roshan-Milani, S; Saboory, E	1
Fujimoto, Y; Funao, T; Mori, T; Nishikawa, K; Suehiro, K; Takahashi, R	1
Isbister, GK; Ryan, NM	1
Fung, SM; Ho, RY; Kearney, TE; Tsutaoka, BT	1
Elassal, MA; Kamel, EM; Kandil, A; Khater, AH; Moustafa, R; Reda, W; Said, HG; Seifeldin, AF; Sobhy, MH	1
Abo Elfetoh, N; Farghaly, HSM; Gabra, RH; Khedr, EM; Noaman, M	1
Katz, KD	1
Kumar, M; Rehni, AK; Singh, I	1
Afshari, R; Ghooshkhanehee, H	1
Abdollahi, M; Asadi, Z; Fayaznouri, M; Panahandeh, R; Talaie, H	1
Arora, S; Rehni, AK; Singh, N; Singh, TG	1
Roberts, DJ; Stellpflug, SJ	1
Afshari, R; Tashakori, A	1
Asghari-Roodsari, A; Dehpour, AR; Javadi-Paydar, M; Khodadad, TK; Lesani, A; Norouzi, A; Shirkhodaei, M	1
Claudet, I; Honorat, R; Maréchal, C	1
Barber, J	1
Abdollahi, M; Afshari, R; Dart, RC; Mehrpour, O; Seghatoleslami, A; Taghaddosinejad, F	1
Bankstahl, JP; Bankstahl, M; Bloms-Funke, P; Löscher, W	1
Dai, Y; Li, X; Zuo, Y	1
Dart, RC; Emamhadi, M; Nikniya, M; Sanaei-Zadeh, H; Zamani, N	1
Brent, J; Hafezi, P; Mousavi-Fatemi, K; Shadnia, S; Soltaninejad, K	1
Farajidana, H; Hassanian-Moghaddam, H; Sanaei-Zadeh, H; Zamani, N	1
Bekjarovski, N; Chaparoska, D; Radulovikj-Bekjarovska, S	1
Azouma, A; Maiga, DD; Seyni, H; Sidikou, A	1
Berkovic, SF; Labate, A; Newton, MR; Vernon, GM	1
Albertson, TE; Alsop, JA; Marquardt, KA	1
Boyd, IW	1
Jovanović-Cupić, V; Martinović, Z; Nesić, N	1
Raffa, RB; Stone, DJ	1
Ehrenreich, H; Poser, W	1
Anderson, DL; Benson, BE; Gorman, SE; Ruskosky, DR; Spiller, HA; Stancavage, MM; Villalobos, D	1
Tobias, JD	1
Alderfer, RJ; Graham, DJ; Kahn, LH	1
Manocha, A; Mediratta, PK; Sharma, KK	1
Rawitscher, L; Reus, VI	1
Derby, L; Gasse, C; Jick, H; Vasilakis-Scaramozza, C	1
Levine, BS; Pestaner, JP; Ripple, MG; Smialek, JE	1
Alderfer, R; Anderson, G; Blough, D; Drinkard, CR; Gardner, JS; Graham, D; Shatin, D	1

Reviews

4 review(s) available for tramadol and Seizures

Article	Year
Neurobehavioral Consequences Associated with Long Term Tramadol Utilization and Pathological Mechanisms. CNS & neurological disorders drug targets, 2019, Volume: 18, Issue:10 Topics: Analgesics, Opioid; Animals; Humans; Parkinson Disease, Secondary; Seizures; Serotonin Syndrome; Tramadol	2019
Tramadol: Understanding the Risk of Serotonin Syndrome and Seizures. The American journal of medicine, 2018, Volume: 131, Issue:11 Topics: Analgesics, Opioid; Anticonvulsants; Humans; Risk Factors; Seizures; Serotonin Syndrome; Tramadol	2018
[Convulsive crisis in Tramadol and caffeine abusers: about 8 cases and review of the literature]. The Pan African medical journal, 2012, Volume: 13 Topics: Adolescent; Adult; Analgesics, Opioid; Caffeine; Central Nervous System Stimulants; Humans; Retrospective Studies; Seizures; Substance-Related Disorders; Tramadol; Young Adult	2012
Lethal combination of tramadol and multiple drugs affecting serotonin. The American journal of forensic medicine and pathology, 2000, Volume: 21, Issue:4 Topics: Adult; Alcoholism; Analgesics, Opioid; Cyclohexanols; Dibenzothiazepines; Drug Interactions; Fatal Outcome; Humans; Lorazepam; Male; MEDLINE; Mental Processes; Quetiapine Fumarate; Receptors, Serotonin; Seizures; Selective Serotonin Reuptake Inhibitors; Smoking; Tramadol; Trazodone; Venlafaxine Hydrochloride	2000

Other Studies

60 other study(ies) available for tramadol and Seizures

Article	Year
The effects of quercetin on seizure, inflammation parameters and oxidative stress in acute on chronic tramadol intoxication. BMC pharmacology & toxicology, 2021, 10-19, Volume: 22, Issue:1 Topics: Adrenal Glands; Analgesics, Opioid; Animals; Brain; Drug Overdose; Heart; Inflammation; Kidney; Liver; Male; Malondialdehyde; Myocardium; Nitric Oxide; Oxidative Stress; Quercetin; Rats, Wistar; Seizures; Thiobarbituric Acid Reactive Substances; Tramadol	2021
Association between tramadol use and seizures: A nationwide case-case-time-control study. Pharmacoepidemiology and drug safety, 2022, Volume: 31, Issue:6 Topics: Analgesics, Opioid; Case-Control Studies; Cross-Over Studies; Female; Humans; Male; Middle Aged; Odds Ratio; Seizures; Tramadol	2022
Tramadol-Induced Acute Seizures: A Report of Three Cases. West African journal of medicine, 2022, Jan-31, Volume: 39, Issue:1 Topics: Adult; Analgesics, Opioid; Humans; Male; Nigeria; Seizures; Tramadol; Young Adult	2022
Massive tramadol ingestion resulting in fatal brain injury - a pharmacokinetic study with discussion on the involved mechanisms of toxicity. Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:9 Topics: Adult; Analgesics, Opioid; Brain Injuries; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Delayed-Action Preparations; Eating; Female; Genotype; Humans; Seizures; Tramadol	2022
Factors associated with seizure in tramadol overdose: a 12-year retrospective study in Hong Kong. Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:11 Topics: Adult; Analgesics, Opioid; Child; Drug Overdose; Female; Hong Kong; Humans; Male; Retrospective Studies; Seizures; Tachycardia, Sinus; Tramadol	2022
Incidence and predictors of post stroke seizure among adult stroke patients admitted at Felege Hiwot compressive specialized hospital, Bahir Dar, North West Ethiopia, 2021: a retrospective follow up study. BMC neurology, 2023, Jan-25, Volume: 23, Issue:1 Topics: Adult; Aged; Ethiopia; Follow-Up Studies; Hospitals; Humans; Incidence; Retrospective Studies; Seizures; Stroke; Tramadol	2023
Zinc oxide calcium silicate composite attenuates acute tramadol toxicity in mice. BMC pharmacology & toxicology, 2023, 02-09, Volume: 24, Issue:1 Topics: Analgesics, Opioid; Animals; Calcium Compounds; Mice; Seizures; Tramadol; Zinc Oxide	2023
Clinical and Laboratory Factors Related to Seizure and Serotonin Toxicity in Tramadol Intoxication: An Egyptian Study. Clinical drug investigation, 2023, Volume: 43, Issue:12 Topics: Adult; Analgesics, Opioid; Drug Overdose; Egypt; Female; Humans; Male; Prospective Studies; Seizures; Serotonin; Tramadol	2023
Long-time effects of prenatal morphine, tramadol, methadone, and buprenorphine exposure on seizure and anxiety in immature rats. The International journal of neuroscience, 2020, Volume: 130, Issue:9 Topics: Animals; Animals, Newborn; Anxiety; Behavior, Animal; Buprenorphine; Female; Locomotion; Male; Maze Learning; Methadone; Morphine; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Seizures; Sex Factors; Tramadol	2020
Tramadol-associated seizures in Egypt: Epidemiological, clinical, and radiological study. Neurotoxicology, 2020, Volume: 79 Topics: Adolescent; Adult; Analgesics, Opioid; Automobile Driving; Brain; Brain Waves; Cross-Sectional Studies; Egypt; Electroencephalography; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Occupations; Retrospective Studies; Risk Assessment; Risk Factors; Seizures; Sex Factors; Time Factors; Tramadol; Young Adult	2020
Preconditioning by ultra-low dose of tramadol reduces the severity of tramadol-induced seizure: Contribution of glutamate receptors. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 133 Topics: Analgesics, Opioid; Animals; Anticonvulsants; Brain; Calcium-Binding Proteins; Calponins; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Male; Microfilament Proteins; Neuropeptides; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Severity of Illness Index; Tramadol	2021
Machine learning algorithms to predict seizure due to acute tramadol poisoning. Human & experimental toxicology, 2021, Volume: 40, Issue:8 Topics: Adolescent; Adult; Analgesics, Opioid; Bayes Theorem; Bicarbonates; Decision Making; Emergency Service, Hospital; Female; Humans; Hydrogen-Ion Concentration; Machine Learning; Male; Models, Biological; Neural Networks, Computer; Pulse; Seizures; Sex Characteristics; Tramadol; Young Adult	2021
The effects of naloxone, diazepam, and quercetin on seizure and sedation in acute on chronic tramadol administration: an experimental study. Behavioral and brain functions : BBF, 2021, May-29, Volume: 17, Issue:1 Topics: Animals; Diazepam; Male; Naloxone; Quercetin; Rats; Rats, Wistar; Seizures; Tramadol	2021
Is naloxone the best antidote to reverse tramadol-induced neuro-respiratory toxicity in overdose? An experimental investigation in the rat. Clinical toxicology (Philadelphia, Pa.), 2018, Volume: 56, Issue:8 Topics: Analgesics, Opioid; Animals; Antidotes; Drug Overdose; Naloxone; Rats; Rats, Sprague-Dawley; Respiratory Insufficiency; Seizures; Tramadol	2018
High-dose thiotepa-related neurotoxicity and the role of tramadol in children. BMC cancer, 2018, 02-13, Volume: 18, Issue:1 Topics: Adolescent; Analgesics, Opioid; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Synergism; Female; Headache; Humans; Male; Multivariate Analysis; Neoplasms; Neurotoxicity Syndromes; Retrospective Studies; Seizures; Thiotepa; Tramadol	2018
Correlation between plasma concentrations of tramadol and its metabolites and the incidence of seizure in tramadol-intoxicated patients. Drug metabolism and personalized therapy, 2018, 06-27, Volume: 33, Issue:2 Topics: Adolescent; Adult; Analgesics, Opioid; Biotransformation; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Humans; Incidence; Iran; Male; Prospective Studies; Risk Factors; Seizures; Sex Factors; Toxicokinetics; Tramadol; Young Adult	2018
Demographic Characteristics and Functional Performance of the Kidneys and Hearts of Patients with Acute Tramadol Toxicity. Drug research, 2019, Volume: 69, Issue:4 Topics: Adolescent; Adult; Analgesics, Opioid; Codeine; Cross-Sectional Studies; Demography; Drug Overdose; Female; Heart; Humans; Iran; Kidney; Male; Physical Functional Performance; Receptors, Opioid, mu; Seizures; Single-Blind Method; Tramadol; Young Adult	2019
Tramadol: Distinguishing the Pathophysiology of Serotonin Syndrome and Seizures. The American journal of medicine, 2018, Volume: 131, Issue:11 Topics: Analgesics, Opioid; Humans; Seizures; Serotonin Syndrome; Tramadol	2018
Seizures induced by tramadol overdose: what is the respective contribution of tramadol and each of its metabolites? Drug metabolism and personalized therapy, 2019, 02-28, Volume: 34, Issue:1 Topics: Drug Overdose; Humans; Incidence; Seizures; Tramadol	2019
Tramadol and the risk of seizure: nested case-control study of US patients with employer-sponsored health benefits. BMJ open, 2019, 03-13, Volume: 9, Issue:3 Topics: Adolescent; Adult; Analgesics, Opioid; Case-Control Studies; Codeine; Female; Health Benefit Plans, Employee; Humans; Insurance, Health; Male; Middle Aged; Retrospective Studies; Seizures; Tramadol; United States; United States Food and Drug Administration; Young Adult	2019
Understanding the risk of seizure in tramadol overdose: still a long way to go. Clinical toxicology (Philadelphia, Pa.), 2019, Volume: 57, Issue:12 Topics: Causality; Drug Overdose; Humans; Naloxone; Registries; Seizures; Tramadol	2019
Tramadol, naloxone, and seizures. Clinical toxicology (Philadelphia, Pa.), 2019, Volume: 57, Issue:12 Topics: Causality; Humans; Naloxone; Registries; Seizures; Tramadol	2019
In reply to Dr. Chhabra, Dr. Mégarbane, and colleagues. Clinical toxicology (Philadelphia, Pa.), 2019, Volume: 57, Issue:12 Topics: Causality; Humans; Naloxone; Registries; Seizures; Tramadol	2019
Caffeine attenuates seizure and brain mitochondrial disruption induced by Tramadol: the role of adenosinergic pathway. Drug and chemical toxicology, 2021, Volume: 44, Issue:6 Topics: Animals; Brain; Caffeine; Disease Models, Animal; Mice; Mitochondria; Protein Carbonylation; Seizures; Tramadol	2021
Proconvulsant effects of tramadol and morphine on pentylenetetrazol-induced seizures in adult rats using different routes of administration. Epilepsy & behavior : E&B, 2014, Volume: 36 Topics: Analgesics; Animals; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Synergism; Female; Morphine; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Time Factors; Tramadol	2014
Brain serotonin content regulates the manifestation of tramadol-induced seizures in rats: disparity between tramadol-induced seizure and serotonin syndrome. Anesthesiology, 2015, Volume: 122, Issue:1 Topics: Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; Male; Rats; Rats, Sprague-Dawley; Seizures; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Serotonin Syndrome; Tramadol	2015
Tramadol overdose causes seizures and respiratory depression but serotonin toxicity appears unlikely. Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:6 Topics: Adult; Analgesics, Opioid; Brain; Brain Waves; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Lung; Male; Middle Aged; New South Wales; Prognosis; Respiration; Respiratory Insufficiency; Retrospective Studies; Risk Factors; Seizures; Serotonin Syndrome; Severity of Illness Index; Tertiary Care Centers; Tramadol	2015
Comparative Toxicity of Tapentadol and Tramadol Utilizing Data Reported to the National Poison Data System. The Annals of pharmacotherapy, 2015, Volume: 49, Issue:12 Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Analgesics, Opioid; Child; Child, Preschool; Drug Overdose; Female; Humans; Infant; Male; Middle Aged; Phenols; Poison Control Centers; Retrospective Studies; Risk; Seizures; Tapentadol; Tramadol; Vomiting; Young Adult	2015
Latarjet Procedure for Anterior Shoulder Instability Due to Tramadol-Induced Seizures: A Multicenter Study. The American journal of sports medicine, 2016, Volume: 44, Issue:4 Topics: Adult; Analgesics, Opioid; Female; Humans; Joint Instability; Male; Opioid-Related Disorders; Orthopedic Procedures; Patient Satisfaction; Prospective Studies; Seizures; Shoulder Dislocation; Shoulder Joint; Tramadol	2016
Cortical excitability in tramadol dependent patients: A transcranial magnetic stimulation study. Drug and alcohol dependence, 2016, Dec-01, Volume: 169 Topics: Adult; Analgesics, Opioid; Cortical Excitability; Evoked Potentials, Motor; Humans; Male; Motor Cortex; Neural Inhibition; Opioid-Related Disorders; Rest; Seizures; Tramadol; Transcranial Magnetic Stimulation; Young Adult	2016
Tramadol is an opioid. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2008, Volume: 4, Issue:2 Topics: Analgesics, Opioid; Consumer Product Safety; Drug Interactions; Humans; Patient Education as Topic; Seizures; Terminology as Topic; Tramadol	2008
Tramadol-induced seizurogenic effect: a possible role of opioid-dependent gamma-aminobutyric acid inhibitory pathway. Basic & clinical pharmacology & toxicology, 2008, Volume: 103, Issue:3 Topics: Amines; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; Naloxone; Narcotic Antagonists; Pentylenetetrazole; Receptors, GABA; Receptors, Opioid; Seizures; Tramadol	2008
Tramadol overdose induced seizure, dramatic rise of CPK and acute renal failure. JPMA. The Journal of the Pakistan Medical Association, 2009, Volume: 59, Issue:3 Topics: Acute Kidney Injury; Adult; Analgesics, Opioid; Drug Overdose; Humans; Male; Seizures; Suicide, Attempted; Tramadol	2009
Dose-independent occurrence of seizure with tramadol. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2009, Volume: 5, Issue:2 Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Brain; Cross-Sectional Studies; Dose-Response Relationship, Drug; Electroencephalography; Female; Humans; Iran; Male; Middle Aged; Seizures; Tomography, X-Ray Computed; Tramadol; Young Adult	2009
Tramadol-induced seizurogenic effect: a possible role of opioid-dependent histamine H1 receptor activation-linked mechanism. Naunyn-Schmiedeberg's archives of pharmacology, 2010, Volume: 381, Issue:1 Topics: Analgesics, Opioid; Animals; Histamine H1 Antagonists, Non-Sedating; Male; Mice; Receptors, Histamine H1; Seizures; Tramadol	2010
Which xenobiotic(s) could be responsible for the radiologic findings below? Answer: any proconvulsant xenobiotic, in this case tramadol, bupropion, and nortriptyline. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2010, Volume: 6, Issue:1 Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Back Pain; Bupropion; Drug Synergism; Female; Humans; Magnetic Resonance Imaging; Nortriptyline; Radiography; Seizures; Spinal Fractures; Thoracic Vertebrae; Tramadol	2010
Tramadol overdose as a cause of serotonin syndrome: a case series. Clinical toxicology (Philadelphia, Pa.), 2010, Volume: 48, Issue:4 Topics: Adult; Demography; Drug Overdose; Female; Humans; Male; Prospective Studies; Seizures; Serotonin Syndrome; Substance-Related Disorders; Tramadol	2010
Involvement of the nitric oxide pathway in the anticonvulsant effect of tramadol on pentylenetetrazole-induced seizures in mice. Epilepsy & behavior : E&B, 2010, Volume: 19, Issue:3 Topics: Analysis of Variance; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Male; Mice; Mice, Inbred Strains; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures; Signal Transduction; Time Factors; Tramadol	2010
Serotonin syndrome induced by tramadol intoxication in an 8-month-old infant. Pediatric neurology, 2011, Volume: 44, Issue:1 Topics: Analgesics, Opioid; Epistaxis; Female; Fever; Glasgow Coma Scale; Hemodynamics; Humans; Infant; Reflex; Seizures; Serotonin Syndrome; Tramadol	2011
Examining the use of tramadol hydrochloride as an antidepressant. Experimental and clinical psychopharmacology, 2011, Volume: 19, Issue:2 Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Drug Tolerance; Humans; Mice; Rats; Respiration; Seizures; Sleep; Substance Withdrawal Syndrome; Substance-Related Disorders; Tramadol	2011
Factors related to seizure in tramadol poisoning and its blood concentration. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2011, Volume: 7, Issue:3 Topics: Adolescent; Adult; Age Factors; Analgesics, Opioid; Chromatography, Gas; Dose-Response Relationship, Drug; Drug Overdose; Female; Glasgow Coma Scale; Humans; Iran; Male; Middle Aged; Poisoning; Prospective Studies; Seizures; Sex Factors; Tramadol; Young Adult	2011
Striking differences in proconvulsant-induced alterations of seizure threshold in two rat models. Neurotoxicology, 2012, Volume: 33, Issue:1 Topics: Animals; Anticonvulsants; Caffeine; Central Nervous System Stimulants; Chlorpromazine; Convulsants; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Electroshock; Male; Pentylenetetrazole; Phenobarbital; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Reaction Time; Seizures; Theophylline; Time Factors; Tramadol	2012
Children's seizures caused by continuous intravenous infusion of tramadol analgesia: two rare case reports. Paediatric anaesthesia, 2012, Volume: 22, Issue:3 Topics: Analgesics, Opioid; Anesthesia, General; Child, Preschool; Heart Rate; Humans; Hypospadias; Infant; Infusions, Intravenous; Male; Pain, Postoperative; Seizures; Teratoma; Tramadol; Urethra	2012
Electrocardiographic manifestations of tramadol toxicity with special reference to their ability for prediction of seizures. The American journal of emergency medicine, 2012, Volume: 30, Issue:8 Topics: Adolescent; Adult; Analgesics, Opioid; Child; Electrocardiography; Heart; Heart Rate; Humans; Male; Middle Aged; Predictive Value of Tests; Retrospective Studies; Seizures; Tramadol; Young Adult	2012
Recurrent seizures in tramadol intoxication: implications for therapy based on 100 patients. Basic & clinical pharmacology & toxicology, 2012, Volume: 111, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Anticonvulsants; Child; Female; Humans; Incidence; Male; Middle Aged; Prescription Drug Misuse; Retrospective Studies; Seizures; Tramadol; Young Adult	2012
Tramadol-induced seizures and trauma. European review for medical and pharmacological sciences, 2012, Volume: 16 Suppl 1 Topics: Adolescent; Adult; Analgesics, Opioid; Child; Child, Preschool; Drug Overdose; Female; Humans; Male; Middle Aged; Retrospective Studies; Seizures; Substance-Related Disorders; Suicide, Attempted; Tramadol; Wounds and Injuries; Young Adult	2012
Seizures after use and abuse of tramadol. Prilozi, 2012, Volume: 33, Issue:1 Topics: Adult; Analgesics, Opioid; Female; Heroin Dependence; Humans; Male; Middle Aged; Seizures; Suicide, Attempted; Tramadol	2012
Tramadol and new-onset seizures. The Medical journal of Australia, 2005, Jan-03, Volume: 182, Issue:1 Topics: Adolescent; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Risk Assessment; Seizures; Tramadol	2005
Tramadol exposures reported to statewide poison control system. The Annals of pharmacotherapy, 2005, Volume: 39, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; California; Central Nervous System; Child; Child, Preschool; Depression; Drug Overdose; Female; Humans; Infant; Logistic Models; Male; Medication Errors; Middle Aged; Nausea; Poison Control Centers; Retrospective Studies; Seizures; Self Administration; Self Medication; Suicide, Attempted; Tachycardia; Time Factors; Tramadol; Vomiting	2005
Tramadol and seizures. The Medical journal of Australia, 2005, Jun-06, Volume: 182, Issue:11 Topics: Analgesics, Opioid; Australia; Drug Interactions; Humans; Seizures; Tramadol	2005
Seizures associated with intoxication and abuse of tramadol. Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:2 Topics: Adolescent; Adult; Drug Synergism; Electroencephalography; Female; Humans; Male; Narcotics; Prospective Studies; Seizures; Substance-Related Disorders; Tramadol	2006
Unexceptional seizure potential of tramadol or its enantiomers or metabolites in mice. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:2 Topics: Analgesics, Opioid; Animals; Codeine; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Hot Temperature; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Quinidine; Reserpine; Seizures; Stereoisomerism; Tramadol	2008
Dependence on tramadol. The Clinical investigator, 1993, Volume: 72, Issue:1 Topics: Adult; Drug Tolerance; Euphoria; Female; Humans; Naltrexone; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders; Tramadol	1993
Prospective multicenter evaluation of tramadol exposure. Journal of toxicology. Clinical toxicology, 1997, Volume: 35, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Child; Child, Preschool; Drug Overdose; Female; Humans; Infant; Male; Middle Aged; Naloxone; Narcotic Antagonists; Poison Control Centers; Prospective Studies; Seizures; Tramadol	1997
Seizure after overdose of tramadol. Southern medical journal, 1997, Volume: 90, Issue:8 Topics: Analgesics, Opioid; Drug Overdose; Female; Humans; Infant; Injections, Intravenous; Seizures; Tramadol	1997
Seizures reported with tramadol. JAMA, 1997, Nov-26, Volume: 278, Issue:20 Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Humans; Seizures; Tramadol	1997
Tramadol, a centrally acting opioid: anticonvulsant effect against maximal electroshock seizure in mice. Indian journal of physiology and pharmacology, 1998, Volume: 42, Issue:3 Topics: Animals; Anticonvulsants; Benzomorphans; Drug Interactions; Electroshock; Female; Male; Mice; Naloxone; Narcotic Antagonists; Receptors, Opioid, kappa; Seizures; Tramadol	1998
Possible interaction of tramadol and antidepressants. The American journal of psychiatry, 2000, Volume: 157, Issue:5 Topics: Antidepressive Agents; Drug Interactions; Drug Therapy, Combination; Female; Fluoxetine; Humans; Obsessive-Compulsive Disorder; Seizures; Selective Serotonin Reuptake Inhibitors; Tramadol	2000
Incidence of first-time idiopathic seizures in users of tramadol. Pharmacotherapy, 2000, Volume: 20, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Case-Control Studies; Child; Child, Preschool; Female; Humans; Incidence; Infant; Male; Middle Aged; Seizures; Tramadol	2000
Tramadol and seizures: a surveillance study in a managed care population. Pharmacotherapy, 2000, Volume: 20, Issue:12 Topics: Adolescent; Adult; Age Factors; Aged; Analgesics, Opioid; Case-Control Studies; Cohort Studies; Drug Interactions; Female; Humans; Insurance Claim Review; Longitudinal Studies; Male; Managed Care Programs; Medical Records; Middle Aged; Reproducibility of Results; Retrospective Studies; Risk Factors; Seizures; Tramadol	2000