Page last updated: 2024-11-05

phenaglycodol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Phenaglycodol is a sedative-hypnotic drug that was first synthesized in 1952. It is a derivative of glycerol and is structurally similar to meprobamate. Phenaglycodol has been shown to have anxiolytic, sedative, and muscle relaxant effects in animal studies. However, it has been largely replaced by other drugs with more favorable side effect profiles. Phenaglycodol is still studied in some research settings, particularly in relation to its potential for the treatment of anxiety and insomnia. The mechanisms of action of phenaglycodol are not fully understood, but it is believed to act on the central nervous system by modulating GABAergic neurotransmission.'

phenaglycodol: structure in Merck Index, 9th ed, #6992; minor descriptor (66-79); on-line and Index Medicus search BUTANEDIOLS (66-79); minor descriptor (66-79); file maintained to BUTYLENE GLYCOLS [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6617
CHEMBL ID2105293
CHEBI ID134889
SCHEMBL ID259155
MeSH IDM0090245

Synonyms (60)

Synonym
atadiol
2, 2-(4-chlorophenyl)-3-methyl-
79-93-6
felixyn
phenylglycodol
nsc169451
wln: qx1&1&xq1&r dg
b586
usaf el-44
nsc-169451
stesil
ultran
fenaglicodolo
phenaglycodol
acalmid
pausital
2-p-chlorophenyl-3-methyl-2,3-butanediol
remin
phenglykodol
ent 15,208
sinforil
acalo
2, 2-(p-chlorophenyl)-3-methyl-
sedapsin
alterton
2-(4-chlorophenyl)-3-methylbutane-2,3-diol
2-(p-chlorophenyl)-3-methyl-2,3-butanediol
fenaglycodol [czech]
phenaglycodolum [inn-latin]
brn 2209509
einecs 201-235-3
nsc 169451
2-(4-chlorophenyl)-3-methyl-2,3-butanediol
2,3-butanediol, 2-(4-chlorophenyl)-3-methyl-
2,3-butanediol, 2-(p-chlorophenyl)-3-methyl-
fenaglicodol [inn-spanish]
phenaglycodol [inn:ban]
nsc63894
nsc-63894
NCIOPEN2_002720
CHEBI:134889
CHEMBL2105293
lmq31ku50k ,
fenaglycodol
4-06-00-06040 (beilstein handbook reference)
unii-lmq31ku50k
phenaglycodolum
fenaglicodol
phenaglycodol [who-dd]
(+/-)-2-(p-chlorophenyl)-3-methyl-2,3-butanediol
phenaglycodol [inn]
SCHEMBL259155
HTYIXCKSEQQCJO-UHFFFAOYSA-N
DTXSID6023444
AKOS028110222
2,3-butanediol, 2-(4-chlorophenyl)-3-methyl- (9ci)
Q19598565
nsc 63894; sinforil; stesil; ultran
felixin
puasital
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
alkylbenzeneA monocyclic arene that is benzene substituted with one or more alkyl groups.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (29)

TimeframeStudies, This Drug (%)All Drugs %
pre-199029 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 22.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index22.66 (24.57)
Research Supply Index3.43 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (22.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other30 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]