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bemegride and Seizures

bemegride has been researched along with Seizures in 80 studies

Bemegride: A CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Folic acid deficient diet reduces the duration and severity of intravenous megimide seizures in the rat after 6 months of diet."7.65Reduction of duration and severity of megimide seizures in rats on a folic acid deficient diet. ( Hommes, OR; Jansen, MJ; Kok, JC; ten Berge, EJ, 1977)
"The bemegride test was considered as diagnostically helpful in 37 cases (86%) based on observations of the course."5.27[EEG activation using bemegride in the diagnosis of epilepsy. 2. Catamnestic studies]. ( Bülau, P; Fröscher, W, 1984)
" It has been found in experimental primary-generalized epileptic activity induced by bemegride that preliminary injection of nicotinamide increased the latency of the emergence of the first epileptic seizures."3.66[Effect of nicotinamide on focal and generalized epileptic activity in the cerebral cortex]. ( Braslavskiĭ, VE; Germanov, SB; Kryzhanovskiĭ, GN; Nikushkin, EV; Shchavelev, VA, 1982)
" An analogous effect was also observed in the development of general convulsive seizures induced in rats by injection of bemegride."3.66[Increase in the peroxidation of neuron membrane lipids, one of the pathogenetic mechanisms of epileptic activity]. ( Braslavskiĭ, VE; Kryzhanovskiĭ, GN; Nikushkin, EV, 1981)
" L-5418 and dephenylhydantoin did not increase the threshold of seizures induced by bemegride while trimethadione raised the threshold."3.66Anti-convulsant effect of phthalazino-[2,3b]-phthalazine-5(14H), 12(7H)-dione (L-5418). II. Electroencephalographic study. ( Fujimura, H; Go, K; Tsurumi, K, 1978)
"Folic acid deficient diet reduces the duration and severity of intravenous megimide seizures in the rat after 6 months of diet."3.65Reduction of duration and severity of megimide seizures in rats on a folic acid deficient diet. ( Hommes, OR; Jansen, MJ; Kok, JC; ten Berge, EJ, 1977)
"The occurrence of audiogenic seizures in mice has been used as the basis of a method for measuring the antagonism between sodium thiopentone and bemegride or leptazol."3.64Drug antagonism and audiogenic seizures in mice. ( WILSON, CW, 1959)
"Generalized convulsive seizures can be triggered by sensory stimuli in animals treated with subthreshold levels of convulsant drugs."2.37Mechanisms of sensory seizures: brain-stem neuronal response changes and convulsant drugs. ( Caspary, DM; Faingold, CL; Hoffmann, WE, 1985)
"Bemegride activation was performed in order to evaluate the predisposition of epileptogenicity of FSECs."1.40Electroencephalographic features of familial spontaneous epileptic cats. ( Fujita, M; Hamamoto, Y; Hasegawa, D; Kuwabara, T; Matsuki, N; Mizoguchi, S; Ogawa, F; Uchida, K, 2014)
"Because of poor seizure even at maximum electrical dosage, aminophylline was administered just before initiating electroconvulsive therapy."1.35Bemegride lengthens seizure duration during electric convulsive therapy in a schizophrenic patient with increased seizure threshold. ( Kaneko, S; Katagai, H; Kikuchi, A; Yasui-Furukori, N, 2009)
"Cinnarizine has an objective stabilizing and anticonvulsive effect on the brain tissue."1.28Protective effect of cinnarizine against convulsive elevation of nonesterified fatty acids in CNS. ( Chmela, Z; Navrátil, J; Sklenovský, A, 1990)
"The bemegride test was considered as diagnostically helpful in 37 cases (86%) based on observations of the course."1.27[EEG activation using bemegride in the diagnosis of epilepsy. 2. Catamnestic studies]. ( Bülau, P; Fröscher, W, 1984)
"The difficulty of developing convulsive seizure in rhesus monkeys suggests that this species is particularly suited for the study of partial complex seizure."1.26Secondarily generalized convulsive seizures induced by daily amygdaloid stimulation in rhesus monkeys. ( Mizoguchi, T; Osawa, T; Wada, JA, 1978)
"Glycogen was depleted only by amphetamine-like compounds or by bemegride-induced convulsions."1.25Physiological and drug-induced changes in the glycogen content of mouse brain. ( Hutchins, DA; Rogers, KJ, 1970)

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-199075 (93.75)18.7374
1990's3 (3.75)18.2507
2000's1 (1.25)29.6817
2010's1 (1.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hasegawa, D1
Mizoguchi, S1
Kuwabara, T1
Hamamoto, Y1
Ogawa, F1
Matsuki, N1
Uchida, K1
Fujita, M1
Katagai, H1
Yasui-Furukori, N1
Kikuchi, A1
Kaneko, S1
COHEN, B1
REY-BELLET, J1
BERGMAN, PS1
ECKEL, D1
SEIFEN, E1
WILSON, CW1
CAVAZZUTI, GB1
BENATTI, C1
FUJITA, B1
KLAPETEK, J1
PROCHAZKOVA, V1
SETLIK, L1
KURIHARA, M1
POIRE, R1
ROYER, P1
DEGRAEVE, M1
RUSTIN, C1
LAYCOCK, GM2
SHULMAN, A2
YEN, HC1
SIGG, EB1
WARNER, CL1
KOLUCH, J1
MRNA, B1
RODIN, EA2
FINK, GB1
JUCHAU, MR1
SETNIKAR, I1
MAGISTRETTI, MJ1
POLAK, A1
PLUM, F1
AIZAWA, T1
MURAMATSU, F1
HAMAGUCHI, K1
TOMITA, M1
KAKIMI, R1
TOYODA, M1
DOW, RS1
RAMWELL, PW1
SHAW, JE1
ROOK, JR1
Glötzner, F2
Grüsser, OJ2
Braslavskiĭ, VE2
Shchavelev, VA1
Kryzhanovskiĭ, GN5
Nikushkin, EV4
Germanov, SB2
Sklenovský, A4
Chmela, Z4
Bülau, P1
Fröscher, W1
Strauss, E1
Wada, J1
Kosaka, B1
Mori, K1
Fujita, S1
Kawaguchi, K1
Chikami, T1
Ohno, K1
Tsuji, M1
Onishi, H1
Yamagami, S1
Kawakita, Y1
Voronko, VA1
Stone, WE2
Javid, MJ1
Eigyo, M1
Shiomi, T1
Inoue, Y1
Sakaguchi, I1
Ishibashi, C1
Murata, S1
Koyabu, K1
Matsushita, A1
Adachi, I1
Ueda, M1
Chimote, KV1
Moghe, PJ1
Wada, JA2
Mizoguchi, T1
Osawa, T1
Kumashiro, H1
Aono, T1
Watanabe, K1
Koizumi, S1
Nakanishi, S1
Kaneko, Y1
Ohno, E1
Uemura, S1
Remick, RA1
Soubrie, P1
Simon, P1
Hommes, OR2
ten Berge, EJ1
Jansen, MJ1
Kok, JC1
Hayes, AG1
Gartside, IB1
Straughan, DW1
Go, K1
Tsurumi, K1
Fujimura, H1
Makul'kin, RF1
Shandra, AA1
Järbe, TU1
Johansson, JO1
Turnbull, MJ1
Watkins, JW1
van Duijn, H1
Beckmann, MK1
Navrátil, J2
Sugimoto, K1
Hasegawa, Y1
Minematsu, K1
Yamaguchi, T1
Faingold, CL1
Hoffmann, WE1
Caspary, DM1
Tupeev, IR1
Bordiukov, MM1
Rodin, E3
Onuma, T2
Wasson, S2
Porzak, J2
Rodin, M1
Asami, Y1
Otsuka, M1
Hirohashi, T1
Inaba, S1
Yamamoto, H1
Predescu, V1
Roman, I1
Meyer, JS3
Sakamoto, K1
Akiyama, M2
Yoshida, K1
Yoshitake, S1
Blum, JE1
Haefely, W1
Jalfre, M1
Polc, P1
Schärer, K1
Rümke, CL2
Villeneuve, A1
Chusid, JG1
Kopeloff, LM1
Lüdtke, AH1
Scharrer, P1
Schmidt, L1
Frank, GB2
Jhamandas, K2
Kimura, R1
Murata, T1
Luttges, MW1
Andry, ML1
Arblaster, CI1
Obbens, EA1
Bianchi Saus, A1
Silva Gaudin, E1
Scarabino, R1
Gonzalez, S1
Caldwell, D1
Laginess, D1
Gotoh, F1
Toshitake, S1
Kanda, T1
Shinohara, Y1
Fukuuchi, Y1
Danielsen, J1
Ellebjerg, J1
Hutchins, DA1
Rogers, KJ1
Hahn, F2
May, HU1
Mukawa, J1
Iwata, Y1
Kobayashi, K1
Oku, T1
Whisler, KE1
Tews, JK1
Kretzschmar, R1
Meyer, HJ1
Noordhoek, J1
Hrebícek, J1

Reviews

2 reviews available for bemegride and Seizures

ArticleYear
Mechanisms of sensory seizures: brain-stem neuronal response changes and convulsant drugs.
    Federation proceedings, 1985, Volume: 44, Issue:8

    Topics: Animals; Anticonvulsants; Bemegride; Bicuculline; Convulsants; Neurons; Reticular Formation; Seizure

1985
[Evaluation of the activation methods in epilepsy].
    Acta neurologica latinoamericana, 1967, Volume: 13, Issue:1

    Topics: Adult; Age Factors; Animals; Bemegride; Cats; Cerebral Cortex; Child; Electric Stimulation; Electroe

1967

Trials

2 trials available for bemegride and Seizures

ArticleYear
[Fluorothyl: pharmacological aspect and clinical use].
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1968, Volume: 1, Issue:5

    Topics: Affective Symptoms; Animals; Bemegride; Bipolar Disorder; Central Nervous System Stimulants; Clinica

1968
Comparable EEG activation by megimide and metrazol.
    Epilepsia, 1966, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aged; Bemegride; Body Weight; Clinical Trials as Topic; Electroencephalography; E

1966

Other Studies

76 other studies available for bemegride and Seizures

ArticleYear
Electroencephalographic features of familial spontaneous epileptic cats.
    Epilepsy research, 2014, Volume: 108, Issue:6

    Topics: Animals; Bemegride; Brain; Cats; Convulsants; Disease Models, Animal; Electrodes, Implanted; Electro

2014
Bemegride lengthens seizure duration during electric convulsive therapy in a schizophrenic patient with increased seizure threshold.
    The journal of ECT, 2009, Volume: 25, Issue:1

    Topics: Bemegride; Convulsants; Electroconvulsive Therapy; Humans; Male; Middle Aged; Schizophrenia; Seizure

2009
Electroencephalographic and convulsive responses of patients with brain disease to methetharimide.
    Neurology, 1960, Volume: 10

    Topics: Bemegride; Brain; Brain Diseases; Central Nervous System Stimulants; Electroencephalography; Humans;

1960
[Comparison of the respiratory analeptic and convulsive properties of pentylenetetrazole and bemegride under the influence of morphine].
    Der Anaesthesist, 1960, Volume: 9

    Topics: Bemegride; Central Nervous System Stimulants; Morphine; Pentylenetetrazole; Respiration; Seizures

1960
Drug antagonism and audiogenic seizures in mice.
    British journal of pharmacology and chemotherapy, 1959, Volume: 14

    Topics: Animals; Bemegride; Central Nervous System Stimulants; Convulsants; Drug Antagonism; Epilepsy, Refle

1959
[Significance and diagnostic value of megimide activation in the electroencephalographic study of febrile convulsions in childhood].
    La Clinica pediatrica, 1961, Volume: 43

    Topics: Bemegride; Central Nervous System Stimulants; Electroencephalography; Seizures; Seizures, Febrile

1961
[A case of adversive seizure].
    No to shinkei = Brain and nerve, 1963, Volume: 15

    Topics: Bemegride; Epilepsy; Humans; Lysergic Acid Diethylamide; Seizures

1963
[INDUCTION OF LATENT EPILEPTIC ACTIVITY WITH MEGIMIDE IN TEMPORAL EPILEPSY].
    Ceskoslovenska neurologie, 1963, Volume: 26

    Topics: Bemegride; Epilepsy; Epilepsy, Temporal Lobe; Humans; Seizures; Temporal Lobe

1963
[THE SIGNIFICANCE OF THE ACTIVATION OF EEG TRACINGS WITH BEMEGRIDE IN CONVULSIVE DISEASES].
    Ceskoslovenska neurologie, 1963, Volume: 26

    Topics: Bemegride; Electroencephalography; Enuresis; Epilepsy; Humans; Paralysis; Seizures; Syncope

1963
[SOME PHARMACOLOGICAL EXPERIMENTS ON ANTIDEPRESSANTS--IN REFERENCE TO CEREBRAL MONOAMINES].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1963, Volume: 65

    Topics: 5-Hydroxytryptophan; Antidepressive Agents; Bemegride; Dihydroxyphenylalanine; Eyelids; Fever; Imipr

1963
[EXPERIMENTAL DETERMINATION OF ANTICONVULSANT PROPERTIES OF DICHLORPHENAMIDE BY ELECTROENCEPHALOGRAPHIC STUDY UNDER INTERMITTENT PHOTIC STIMULATION].
    Annales medicales de Nancy, 1963, Volume: 2

    Topics: Acetazolamide; Adolescent; Alcoholism; Anticonvulsants; Anxiety; Bemegride; Dichlorphenamide; Electr

1963
PARTIAL AGONISTS IN THE CENTRAL NERVOUS SYSTEM.
    Nature, 1963, Nov-30, Volume: 200

    Topics: Animals; Anticonvulsants; Bemegride; Central Nervous System Stimulants; Hypnotics and Sedatives; Mic

1963
STIMULANT ACTION OF PYRIDYL DERIVATIVES OF BENZODIOXANS AND BENZODIOXEPANS.
    International journal of neuropharmacology, 1963, Volume: 2

    Topics: Animals; Anticonvulsants; Atropine; Bemegride; Central Nervous System Agents; Central Nervous System

1963
THE CONVULSIVE EFFECT OF BEMEGRID.
    Activitas nervosa superior, 1964, Volume: 6

    Topics: Animals; Bemegride; Lagomorpha; Pentylenetetrazole; Rabbits; Research; Seizures; Toxicology

1964
SOME RELATIONSHIPS OF INDUCED SEIZURE PATTERNS TO CLINICAL FINDINGS IN EPILEPTIC PATIENTS.
    Epilepsia, 1964, Volume: 5

    Topics: Amobarbital; Bemegride; Biomedical Research; Electronic Data Processing; Epilepsy; Epilepsy, Tonic-C

1964
COMPARATIVE NEUROTOXICITY AND ANTIPENTYLENETETRAZOL ACTIVITY OF SOME PIPERIDINEDIONES.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Bemegride; Glutethimide; Hypnotics and Sedatives; Mice; Pentylenetetrazole; Pharmacology; Phenobarbi

1964
CARDIAC EFFECTS OF DIMEFLINE COMPARED WITH THOSE OF OTHER CENTRAL NERVOUS SYSTEM STIMULANTS.
    Archives internationales de pharmacodynamie et de therapie, 1964, Sep-01, Volume: 151

    Topics: Aminobutyrates; Bemegride; Benzene; Calcium; Central Nervous System Stimulants; Chlorides; Coronary

1964
COMPARISON OF NEW ANALEPTICS IN BARBITURATE-POISONED ANIMALS.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 145

    Topics: Barbiturates; Bemegride; Cats; Central Nervous System Stimulants; Dogs; Electroencephalography; Phar

1964
CEREBRAL CIRCULATION, METABOLISM, AND ELECTRICAL ACTIVITY DURING CONVULSION INDUCED BY MEGIMIDE.
    Japanese circulation journal, 1965, Volume: 29

    Topics: Bemegride; Blood Pressure; Blood Pressure Determination; Cats; Cerebrospinal Fluid; Cerebrovascular

1965
EXTRINSIC REGULATORY MECHANISMS OF SEIZURE ACTIVITY.
    Epilepsia, 1965, Volume: 6

    Topics: Bemegride; Brain; Cerebellum; Cobalt; Decerebrate State; Electric Stimulation; Electrophysiology; Ep

1965
THE EFFECT OF PICROTOXIN ON MOTOR ACTIVITY AND THE ELECTROENCEPHALOGRAM OF MICE.
    British journal of pharmacology and chemotherapy, 1965, Volume: 24

    Topics: Amphetamine; Amphetamines; Animals; Bemegride; Blood Pressure; Dextroamphetamine; Electroencephalogr

1965
Ether convulsions controlled by thiopentone and megimide.
    Anaesthesia, 1959, Volume: 14

    Topics: Bemegride; Central Nervous System Stimulants; Ether; Ethers; Seizures; Thiopental

1959
[The cortical DC potential, the EEG and the membrane potential during convulsive activity and hypoxia].
    Revue neurologique, 1967, Volume: 117, Issue:1

    Topics: Action Potentials; Animals; Apnea; Bemegride; Cats; Cerebral Cortex; Electric Stimulation; Electroen

1967
[Effect of nicotinamide on focal and generalized epileptic activity in the cerebral cortex].
    Biulleten' eksperimental'noi biologii i meditsiny, 1982, Volume: 94, Issue:8

    Topics: Animals; Bemegride; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical;

1982
Nonesterified fatty acids in the brain structures--the effect of convulsive activity.
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1984, Volume: 106

    Topics: Animals; Bemegride; Brain; Brain Chemistry; Chromatography, Thin Layer; Fatty Acids, Nonesterified;

1984
The effect of antiepileptic drugs on nonesterified fatty acids in the brain structures during convulsive state.
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1984, Volume: 106

    Topics: Animals; Anticonvulsants; Bemegride; Brain; Diazepam; Drug Evaluation, Preclinical; Fatty Acids, Non

1984
[EEG activation using bemegride in the diagnosis of epilepsy. 2. Catamnestic studies].
    EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete, 1984, Volume: 15, Issue:3

    Topics: Adult; Bemegride; Diagnosis, Differential; Electroencephalography; Epilepsy; False Positive Reaction

1984
Spontaneous facial expressions occurring at onset of focal seizure activity.
    Archives of neurology, 1983, Volume: 40, Issue:9

    Topics: Adolescent; Adult; Bemegride; Child; Child, Preschool; Electroencephalography; Emotions; Facial Expr

1983
Muscarinic cholinergic receptors of the convulsive strain (E1) mouse.
    Folia psychiatrica et neurologica japonica, 1983, Volume: 37, Issue:3

    Topics: Animals; Bemegride; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Quinuclidinyl Benzi

1983
[Endogenous phospholipase hydrolysis in the cerebral cortex during the development of epileptic activity].
    Biulleten' eksperimental'noi biologii i meditsiny, 1982, Volume: 94, Issue:12

    Topics: Animals; Bemegride; Cerebral Cortex; Enzyme Activation; Epilepsies, Partial; Fatty Acids; Hydrolysis

1982
[Increase in the peroxidation of neuron membrane lipids, one of the pathogenetic mechanisms of epileptic activity].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:6

    Topics: Animals; Bemegride; Butylated Hydroxytoluene; Cerebral Cortex; Electroencephalography; Lipid Peroxid

1981
Effects of anticonvulsants and glutamate antagonists on the convulsive action of kainic acid.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 243, Issue:1

    Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bemegride; Bicuculline; Drug Interactions; Excit

1980
Pharmacological studies on a new dihydrothienopyridine calcium antagonist, S-312-d. 5th communication: anticonvulsant effects in mice.
    Japanese journal of pharmacology, 1994, Volume: 65, Issue:2

    Topics: Administration, Oral; Animals; Anticonvulsants; Bemegride; Calcium Channel Blockers; Dihydropyridine

1994
Putative neurotransmitters in CNS and chemoconvulsions.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 228, Issue:2

    Topics: Animals; Bemegride; Catecholamines; Central Nervous System; Female; Male; Mice; Neurotransmitter Age

1977
Secondarily generalized convulsive seizures induced by daily amygdaloid stimulation in rhesus monkeys.
    Neurology, 1978, Volume: 28, Issue:10

    Topics: Amygdala; Animals; Bemegride; Electric Stimulation; Female; Haplorhini; Macaca mulatta; Male; Papio;

1978
DC potential shifts associated with convulsive seizures and brain monoamine changes in rabbits.
    Folia psychiatrica et neurologica japonica, 1977, Volume: 31, Issue:3

    Topics: 5-Hydroxytryptophan; Adolescent; Animals; Bemegride; Brain Damage, Chronic; Caudate Nucleus; Cerebra

1977
Complex partial and pseudoseizure disorders.
    The American journal of psychiatry, 1979, Volume: 136, Issue:3

    Topics: Adult; Bemegride; Brain; Conversion Disorder; Diagnosis, Differential; Electroencephalography; Epile

1979
Comparative study of the antagonism of bemegride and picrotoxin on behavioural depressant effects of diazepam in rats and mice.
    Neuropharmacology, 1978, Volume: 17, Issue:2

    Topics: Amnesia; Animals; Behavior, Animal; Bemegride; Diazepam; Humans; Male; Mice; Motor Activity; Motor S

1978
Reduction of duration and severity of megimide seizures in rats on a folic acid deficient diet.
    Epilepsia, 1977, Volume: 18, Issue:4

    Topics: Animals; Bemegride; Body Weight; Brain Chemistry; Female; Folic Acid; Folic Acid Deficiency; Rats; S

1977
Effect of four convulsants on the time course of presynaptic inhibition and the relation to seizure activity.
    Neuropharmacology, 1977, Volume: 16, Issue:11

    Topics: Animals; Bemegride; Bicuculline; Cerebral Cortex; Convulsants; Instinct; Male; Medulla Oblongata; Ne

1977
Anti-convulsant effect of phthalazino-[2,3b]-phthalazine-5(14H), 12(7H)-dione (L-5418). II. Electroencephalographic study.
    Japanese journal of pharmacology, 1978, Volume: 28, Issue:1

    Topics: Animals; Anticonvulsants; Bemegride; Brain; Electrodes, Implanted; Electroencephalography; Electrosh

1978
[Principle of the determinant and formation of complexes of epileptic activity].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1978, Volume: 78, Issue:4

    Topics: Animals; Bemegride; Cats; Cerebral Cortex; Electrophysiology; Ether; Halothane; Seizures; Strychnine

1978
Pentobarbital, diazepam and bemegride: their effects on open-field behavior in the gerbil (Meriones unguiculatus).
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 225, Issue:1

    Topics: Animals; Behavior, Animal; Bemegride; Body Temperature; Diazepam; Drug Interactions; Female; Gerbill

1977
Determination of halothane-induced sleeping time in the rat: effect of prior administration of centrally active drugs.
    British journal of pharmacology, 1976, Volume: 58, Issue:1

    Topics: Animals; Bemegride; Brain Chemistry; Circadian Rhythm; Drug Interactions; Female; Halothane; Injecti

1976
Dipropylacetic acid (Depakine) in experimental epilepsy in the alert cat.
    Epilepsia, 1975, Volume: 16, Issue:1

    Topics: Animals; Anticonvulsants; Bemegride; Cats; Cobalt; Injections, Intravenous; Injections, Subcutaneous

1975
Protective effect of cinnarizine against convulsive elevation of nonesterified fatty acids in CNS.
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1990, Volume: 126

    Topics: Animals; Bemegride; Brain; Cinnarizine; Fatty Acids, Nonesterified; Male; Rats; Rats, Inbred Strains

1990
Protective effect of nifedipine on convulsive NEFA increase in CNS.
    Activitas nervosa superior, 1990, Volume: 32, Issue:1

    Topics: Animals; Bemegride; Fatty Acids, Nonesterified; Male; Nifedipine; Rats; Rats, Inbred Strains; Seizur

1990
[Aphasic seizure provoked by bemegride administration].
    Rinsho shinkeigaku = Clinical neurology, 1985, Volume: 25, Issue:8

    Topics: Aphasia; Bemegride; Humans; Male; Middle Aged; Seizures

1985
[State of the antioxidant system during induction in rats of primary generalized epileptic activity].
    Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 100, Issue:11

    Topics: Animals; Bemegride; Brain; Glutathione Peroxidase; Glutathione Reductase; Male; Rats; Rats, Inbred S

1985
Neurophysiological mechanisms involved in grand mal seizures induced by Metrazol and Megimide.
    Electroencephalography and clinical neurophysiology, 1971, Volume: 30, Issue:1

    Topics: Amygdala; Animals; Behavior, Animal; Bemegride; Brain; Cats; Caudate Nucleus; Cerebellum; Cerebral C

1971
The synthesis and pharmacology of a novel benzodiazepine derivative, 1-methyl-5-(o-fluorophenyl)-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one(ID-540).
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:10

    Topics: Aggression; Animals; Anti-Anxiety Agents; Behavior, Animal; Bemegride; Benzodiazepinones; Cats; Chlo

1974
Clinical appraisal of activation with Megimide, Baytinal and alcohol in chronic alcoholism.
    Electroencephalography and clinical neurophysiology, 1967, Volume: 22, Issue:6

    Topics: Alcoholism; Antisocial Personality Disorder; Barbiturates; Bemegride; Cerebral Cortex; Electroenceph

1967
Monitoring cerebral blood flow, metabolism and EEG.
    Electroencephalography and clinical neurophysiology, 1967, Volume: 23, Issue:6

    Topics: Acidosis, Respiratory; Animals; Bemegride; Blood Flow Velocity; Carbon Dioxide; Cerebral Arteries; C

1967
Studies on the pathophysiology of "centrencephalic" epilepsy.
    Electroencephalography and clinical neurophysiology, 1969, Volume: 27, Issue:5

    Topics: Animals; Bemegride; Brain Stem; Cats; Cerebral Cortex; Reticular Formation; Seizures

1969
[Pharmacology and toxicology of the anticonvulsant agent clonazepam].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:3

    Topics: Animals; Anticonvulsants; Bemegride; Benzazepines; Brain; Cats; Central Nervous System; Chemical Phe

1973
Increased susceptibility of mice to seizures after some anticonvulsant drugs.
    European journal of pharmacology, 1967, Volume: 1, Issue:5

    Topics: Animals; Anticonvulsants; Bemegride; Central Nervous System Stimulants; Drug Synergism; Electroshock

1967
Use of chronic irritative foci in laboratory evaluation of antiepileptic drugs.
    Epilepsia, 1969, Volume: 10, Issue:2

    Topics: Aluminum; Aminobutyrates; Animals; Bemegride; Central Nervous System Stimulants; Chlordiazepoxide; C

1969
[The effects of Bemegride, Pentetrazole and Nikethamide on blood pressure, heart rate and respiration in alcohol-intoxicated rats].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:10

    Topics: Alcoholic Intoxication; Animals; Bemegride; Blood Pressure; Central Nervous System Stimulants; Heart

1970
Effects of drugs acting alone and in combination on the motor activity of intact mice.
    British journal of pharmacology, 1970, Volume: 39, Issue:4

    Topics: Adjuvants, Anesthesia; Aminobutyrates; Animals; Bemegride; Caffeine; Central Nervous System; Central

1970
Effects of general stimulant drugs on the electrical responses of isolated slabs of cat's cerebral cortex.
    British journal of pharmacology, 1970, Volume: 39, Issue:4

    Topics: Action Potentials; Animals; Bemegride; Caffeine; Cats; Central Nervous System Stimulants; Cerebral C

1970
Influence of alkylamides of glutamic acid and related compounds on the central nervous system. I. Central depressant effect of theanine.
    Chemical & pharmaceutical bulletin, 1971, Volume: 19, Issue:6

    Topics: Amides; Amino Acids; Animals; Bemegride; Brain; Brain Chemistry; Caffeine; Carbon Isotopes; Central

1971
Convulsive activity in garter snakes.
    Behavioral biology, 1972, Volume: 7, Issue:2

    Topics: Animals; Behavior, Animal; Bemegride; Body Temperature; Brain; Central Nervous System; Central Nervo

1972
Bemegride antagonism to the development of physical dependence on barbitone in rodents.
    Experientia, 1974, Sep-15, Volume: 30, Issue:9

    Topics: Animals; Barbiturates; Behavior, Animal; Bemegride; Female; Humans; Rats; Seizures; Substance Withdr

1974
Psychomotor epilepsy and aggressive behavior.
    Archives of general psychiatry, 1973, Volume: 28, Issue:2

    Topics: Acting Out; Adolescent; Aggression; Automatism; Bemegride; Brain Damage, Chronic; Electroencephalogr

1973
Liver function and folate epilepsy in the rat.
    Journal of the neurological sciences, 1973, Volume: 20, Issue:3

    Topics: Animals; Bemegride; Electrocardiography; Electroencephalography; Folic Acid; Hepatectomy; Injections

1973
Photic evoked responses during induced epileptic seizures.
    Epilepsia, 1966, Volume: 7, Issue:3

    Topics: Animals; Bemegride; Cats; Cerebral Cortex; Electric Stimulation; Electroencephalography; Epilepsy, A

1966
Monitoring cerebral blood flow and oxygen, glucose, lactate and ammonia metabolism.
    Circulation research, 1967, Volume: 21, Issue:5

    Topics: Ammonia; Animals; Arteries; Bemegride; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; B

1967
Changes in cerebrospinal fluid sodium and potassium concentrations during seizure activity.
    Neurology, 1970, Volume: 20, Issue:12

    Topics: Animals; Bemegride; Cerebral Arteries; Disease Models, Animal; Haplorhini; Potassium; Seizures; Sodi

1970
Physiological and drug-induced changes in the glycogen content of mouse brain.
    British journal of pharmacology, 1970, Volume: 39, Issue:1

    Topics: Amphetamine; Animals; Bemegride; Body Temperature; Brain Chemistry; Caffeine; Catecholamines; Circad

1970
Concerning the depressant activity of analeptics (pentylenetetrazol, bemegride, nikethamide, picrotoxin).
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 188, Issue:2

    Topics: Anesthesia; Animals; Barbiturates; Bemegride; Depression, Chemical; Guinea Pigs; Nikethamide; Nitrou

1970
[Experimental study on the seizure wave induced by intravenous injection of megimide--in comparison with the induction pattern by metrazol].
    No to shinkei = Brain and nerve, 1967, Volume: 19, Issue:6

    Topics: Animals; Bemegride; Cats; Cerebral Cortex; Electroencephalography; Injections, Intravenous; Pentylen

1967
Cerebral amino acids and lipids in drug-induced status epilepticus.
    Journal of neurochemistry, 1968, Volume: 15, Issue:3

    Topics: Amino Acids; Ammonia; Animals; Bemegride; Brain Chemistry; Dogs; Lipids; Male; Pentylenetetrazole; S

1968
[Membrane potentials and after dis charges of cortical cells, EEG and cortical DC-potentials in generalized convulsions].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1968, Volume: 210, Issue:4

    Topics: Action Potentials; Animals; Bemegride; Cats; Cerebral Cortex; Electric Stimulation; Electroencephalo

1968
[On the inflence of fluid volume on the efficacy of bemegride, Pentetrazole and picrotoxin in phenobarbital poisoning].
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 174, Issue:2

    Topics: Animals; Bemegride; Mice; Pentylenetetrazole; Pharmaceutical Vehicles; Phenobarbital; Picrotoxin; Se

1968
The influence of lynestrenol on the rate of metabolism of phenobarbital, phenytoin and hexobarbital in mice.
    European journal of pharmacology, 1969, Volume: 6, Issue:2

    Topics: Animals; Bemegride; Electroshock; Enzyme Induction; Female; Hexobarbital; Lynestrenol; Male; Mice; P

1969
Latent periods of cortical evoked potentials during postparoxysmal depression of background EEG activity.
    Activitas nervosa superior, 1966, Volume: 8, Issue:1

    Topics: Animals; Bemegride; Cats; Cerebral Cortex; Electroencephalography; Light; Seizures

1966