Page last updated: 2024-08-23

nafimidone and Seizures

nafimidone has been researched along with Seizures in 6 studies

*Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder. [MeSH]

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beedle, EE; Lawson, R; Leander, JD; Robertson, DW1
Beedle, EE; Krushinski, JH; Leander, JD; Rathbun, RC; Robertson, DW; Wong, DT1
Bialer, M; Bibi, D; Mawasi, H1
Acar, MF; Dalkara, S; Sari, S1
Alagöz, MA; Calış, U; Dalkara, S; Karakurt, A; Sayoğlu, B1
Dalkara, S; Karakurt, A; Kendi, E; Ozalp, M; Ozbey, S; Stables, JP1

Other Studies

6 other study(ies) available for nafimidone and Seizures

ArticleYear
Imidazole anticonvulsants: structure-activity relationships of [(biphenylyloxy)alkyl]imidazoles.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:5

    Topics: Animals; Biphenyl Compounds; Chemical Phenomena; Chemistry; Drug Synergism; Hexobarbital; Imidazoles; Male; Mice; Seizures; Sleep; Structure-Activity Relationship

1987
Structure-activity relationships of (arylalkyl)imidazole anticonvulsants: comparison of the (fluorenylalkyl)imidazoles with nafimidone and denzimol.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: Animals; Anticonvulsants; Cerebral Cortex; Chemical Phenomena; Chemistry; Drug Synergism; Female; Flunitrazepam; Hexobarbital; Imidazoles; Mice; Naphazoline; Rats; Rats, Inbred F344; Seizures; Sleep; Structure-Activity Relationship

1986
Design and comparative anticonvulsant activity assessment of CNS-active alkyl-carbamoyl imidazole derivatives.
    Bioorganic & medicinal chemistry, 2016, 09-15, Volume: 24, Issue:18

    Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Carbamates; Electroshock; Imidazoles; Male; Mice; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship

2016
Synthesis, in vivo anticonvulsant testing, and molecular modeling studies of new nafimidone derivatives.
    Drug development research, 2019, Volume: 80, Issue:5

    Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Imidazoles; Injections, Intraperitoneal; Male; Mice; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Naphazoline; Rats; Receptors, GABA-A; Seizures; Structure-Activity Relationship

2019
Synthesis of some novel 1-(2-naphthyl)-2-(imidazol-1-yl)ethanone oxime ester derivatives and evaluation of their anticonvulsant activity.
    European journal of medicinal chemistry, 2012, Volume: 57

    Topics: Animals; Anticonvulsants; Electroshock; Esters; Imidazoles; Isomerism; Mice; Motor Activity; Naphazoline; Neuropsychological Tests; Oximes; Seizures; Structure-Activity Relationship

2012
Synthesis of some 1-(2-naphthyl)-2-(imidazole-1-yl)ethanone oxime and oxime ether derivatives and their anticonvulsant and antimicrobial activities.
    European journal of medicinal chemistry, 2001, Volume: 36, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anticonvulsants; Bacteria; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Electroshock; Ethers; Fungi; Humans; Isomerism; Mice; Microbial Sensitivity Tests; Molecular Conformation; Naphazoline; Oximes; Pentylenetetrazole; Rats; Reflex; Seizures; Structure-Activity Relationship

2001