Page last updated: 2024-10-16

acetaldehyde and Seizures

acetaldehyde has been researched along with Seizures in 17 studies

Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"To prospectively describe clinical signs, therapeutic management, outcomes, and delayed-onset seizures due to metaldehyde poisoning in dogs."4.31A prospective study on clinical signs, management, outcomes, and delayed neurologic sequelae due to metaldehyde poisoning in 26 dogs. ( Berny, P; Dutil, GF, 2023)
"Twelve of 17 dogs had convulsions and survived; 9 were followed up for at least 3 years after poisoning, and none had any other seizure episode or neurological sequelae."1.91A prospective study on clinical signs, management, outcomes, and delayed neurologic sequelae due to metaldehyde poisoning in 26 dogs. ( Berny, P; Dutil, GF, 2023)
"No dog had any further seizures after its SE."1.37Effect of prolonged status epilepticus as a result of intoxication on epileptogenesis in a UK canine population. ( Horton, C; Jull, P; Risio, LD; Volk, HA, 2011)
"The most prevalent clinical signs were seizures, hyperthermia, tachycardia and muscle tremors."1.34Clinical, neurological and clinicopathological signs, treatment and outcome of metaldehyde intoxication in 18 dogs. ( Aroch, I; Segev, G; Yas-Natan, E, 2007)
"Withdrawal seizure prone (WSP) and withdrawal seizure resistant (WRS) mice were genetically selected to express severe or mild handling-induced convulsions (HIC), respectively, after cessation of chronic ethanol (EtOH) vapor inhalation."1.28Acute dependence on depressant drugs is determined by common genes in mice. ( Belknap, JK; Crabbe, JC; Merrill, C, 1991)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199012 (70.59)18.7374
1990's1 (5.88)18.2507
2000's1 (5.88)29.6817
2010's2 (11.76)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Dutil, GF1
Berny, P1
Jull, P1
Risio, LD1
Horton, C1
Volk, HA1
Poncelet, L1
CHRISTEN, JP1
JACCOTTET, M1
Yas-Natan, E1
Segev, G1
Aroch, I1
Homeida, AM2
Cooke, RG2
Longstreth, WT1
Pierson, DJ1
Longbottom, GM1
Gordon, AS1
Stubbings, DP1
Harris, WF1
Crabbe, JC1
Merrill, C1
Belknap, JK1
Webster, CJ1
Webster, JM1
Ortiz, A1
Littleton, JM1
Griffiths, PJ1
Simmons, JR1
Udall, ND1
Mellerio, F1

Other Studies

17 other studies available for acetaldehyde and Seizures

ArticleYear
A prospective study on clinical signs, management, outcomes, and delayed neurologic sequelae due to metaldehyde poisoning in 26 dogs.
    Open veterinary journal, 2023, Volume: 13, Issue:5

    Topics: Acetaldehyde; Animals; Dog Diseases; Dogs; Emetics; Prospective Studies; Seizures

2023
Effect of prolonged status epilepticus as a result of intoxication on epileptogenesis in a UK canine population.
    The Veterinary record, 2011, Oct-01, Volume: 169, Issue:14

    Topics: Acetaldehyde; Animals; Dog Diseases; Dogs; Female; Insecticides; Macrolides; Male; Molluscacides; My

2011
Epileptic brain damage in dogs and cats: myth or reality?
    The Veterinary record, 2011, Oct-01, Volume: 169, Issue:14

    Topics: Acetaldehyde; Animals; Dog Diseases; Female; Male; Molluscacides; Seizures; Status Epilepticus

2011
[Convulsant poisoning in children; meta & asterol].
    Revue medicale de la Suisse romande, 1957, Volume: 77, Issue:9

    Topics: Acetaldehyde; Antifungal Agents; Child; Convulsants; Fungicides, Industrial; Humans; Infant; Seizure

1957
Clinical, neurological and clinicopathological signs, treatment and outcome of metaldehyde intoxication in 18 dogs.
    The Journal of small animal practice, 2007, Volume: 48, Issue:8

    Topics: Acetaldehyde; Animals; Anticonvulsants; Blood Chemical Analysis; Dog Diseases; Dogs; Female; Israel;

2007
Pharmacological aspects of metaldehyde poisoning in mice.
    Journal of veterinary pharmacology and therapeutics, 1982, Volume: 5, Issue:1

    Topics: Acetaldehyde; Animals; Brain; Clonidine; Diazepam; Female; Hydroxyindoleacetic Acid; Male; Mice; Mic

1982
Metaldehyde poisoning from slug bait ingestion.
    The Western journal of medicine, 1982, Volume: 137, Issue:2

    Topics: Acetaldehyde; Adult; Anticonvulsants; Electroencephalography; Female; Humans; Memory Disorders; Moll

1982
Anti-convulsant activity of diazepam and clonidine on metaldehyde-induced seizures in mice: effects on brain gamma-amino butyric acid concentrations and monoamine oxidase activity.
    Journal of veterinary pharmacology and therapeutics, 1982, Volume: 5, Issue:3

    Topics: Acetaldehyde; Animals; Brain Chemistry; Clonidine; Diazepam; Female; gamma-Aminobutyric Acid; Male;

1982
Metaldehyde poisoning in a dairy herd.
    The Veterinary record, 1979, May-19, Volume: 104, Issue:20

    Topics: Acetaldehyde; Animals; Ataxia; Cattle; Cattle Diseases; Female; Molluscacides; Polymers; Seizures; T

1979
Three cases of metaldehyde poisoning in cattle.
    The Veterinary record, 1976, May-01, Volume: 98, Issue:18

    Topics: Acetaldehyde; Animals; Blindness; Cattle; Cattle Diseases; Molluscacides; Movement Disorders; Polyme

1976
Metaldehyde poisoning in three horses.
    Modern veterinary practice, 1975, Volume: 56, Issue:5

    Topics: Acetaldehyde; Animals; Female; Horse Diseases; Horses; Lethal Dose 50; Male; Molluscacides; Polymers

1975
Acute dependence on depressant drugs is determined by common genes in mice.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:2

    Topics: Acetaldehyde; Animals; Butanols; Ethanol; Injections, Intraperitoneal; Male; Mice; Pentobarbital; Se

1991
Anaesthetic control for metaldehyde poisoning.
    The Veterinary record, 1986, Nov-15, Volume: 119, Issue:20

    Topics: Acetaldehyde; Animals; Dog Diseases; Dogs; Molluscacides; Pentobarbital; Seizures

1986
Letter: A simple screening test for drugs of potential use in ethanol withdrawal.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:12

    Topics: Acetaldehyde; Animals; Drug Evaluation, Preclinical; Ethanol; Humans; Male; Mice; Seizures; Substanc

1973
An outbreak of metaldehyde poisoning in sheep.
    The Veterinary record, 1974, Sep-07, Volume: 95, Issue:10

    Topics: Acetaldehyde; Animals; Female; Fever; Polymers; Respiration; Salivation; Seizures; Sheep; Sheep Dise

1974
The toxicity of the molluscicides metaldehyde and methiocarb to dogs.
    The Veterinary record, 1973, Oct-13, Volume: 93, Issue:15

    Topics: Acetaldehyde; Animals; Atropine; Carbamates; Dog Diseases; Dogs; Gluconates; Glucose; Hyperemia; Kid

1973
[Acute poisonings and convulsive crises. Electroencephalographic study of 3 very different products: Rimifon, chloralose, metaldehyde].
    Revue neurologique, 1967, Volume: 117, Issue:3

    Topics: Acetaldehyde; Brain; Chloralose; Coma; Electroencephalography; Humans; Isoniazid; Poisoning; Seizure

1967