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beta-alanine and Seizures

beta-alanine has been researched along with Seizures in 10 studies

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"beta-Alanine is a central-nervous-system depressant."5.24Hyper-beta-alaninemia associated with beta-aminoaciduria and gamma-aminobutyricaciduria, somnolence and seizures. ( Davies, E; Pueschel, S; Scriver, CR, 1966)
"Taurine treatment limited mitochondrial superoxide generation, supporting a role for taurine in maintaining complex I activity."1.43Mitochondrial defects associated with β-alanine toxicity: relevance to hyper-beta-alaninemia. ( Alexeyev, M; Jong, CJ; Mehdi, AB; Schaffer, SW; Shetewy, A; Shimada-Takaura, K; Takahashi, K; Warner, D, 2016)
" Neurotoxic signs such as hyperesthesia and/or excitement, as well as convulsions, were observed in both FBAL x HCl and FA x Na groups; these toxic signs were also found in the UFT group."1.32Neurotoxic effects of alpha-fluoro-beta-alanine (FBAL) and fluoroacetic acid (FA) on dogs. ( Ariyoshi, T; Yada, H; Yamashita, K, 2004)
"Convulsant activity of pazufloxacin mesilate (PZFX mesilate), a new quinolone antibacterial agent for intravenous use, in combination with nonsteroidal anti-inflammatory drug (NSAID) was investigated in mice after intravenous or intracerebroventricular administration."1.31[Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration]. ( Fukuda, H; Kawamura, Y, 2002)
"Diazepam, known to produce its anticonvulsant, sedative and muscle relaxant effects through its interaction either with central GABA or glycine receptors was found to be the most potent (48."1.27Effects of glycine and other inhibitory amino acid neurotransmitters on strychnine convulsive threshold in mice. ( Sangiah, S, 1985)
"Homotaurine is a powerful GABA agonist that exerts a central action upon parenteral administration."1.26Activating effects of homotaurine and taurine on corticoreticular epilepsy. ( Black, JA; Fariello, RG; Golden, GT, 1981)
"beta-Alanine is a central-nervous-system depressant."1.24Hyper-beta-alaninemia associated with beta-aminoaciduria and gamma-aminobutyricaciduria, somnolence and seizures. ( Davies, E; Pueschel, S; Scriver, CR, 1966)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's1 (10.00)18.2507
2000's2 (20.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakada, K1
Yoshikawa, M1
Ide, S1
Suemasa, A1
Kawamura, S1
Kobayashi, T1
Masuda, E1
Ito, Y1
Hayakawa, W1
Katayama, T1
Yamada, S1
Arisawa, M1
Minami, M1
Shuto, S1
Shetewy, A1
Shimada-Takaura, K1
Warner, D1
Jong, CJ1
Mehdi, AB1
Alexeyev, M1
Takahashi, K1
Schaffer, SW1
Fukuda, H1
Kawamura, Y1
Yamashita, K1
Yada, H1
Ariyoshi, T1
Scriver, CR1
Pueschel, S1
Davies, E1
Fariello, RG1
Golden, GT1
Black, JA1
Katsuki, K1
Shinohara, K1
Yamada, T1
Marson, CA1
Hammond, EJ1
Wilder, BJ1
Sangiah, S1

Reviews

1 review available for beta-alanine and Seizures

ArticleYear
Gamma-vinyl GABA.
    General pharmacology, 1985, Volume: 16, Issue:5

    Topics: 4-Aminobutyrate Transaminase; Amino Acids; Aminocaproates; Animals; Behavior, Animal; beta-Alanine;

1985

Other Studies

9 other studies available for beta-alanine and Seizures

ArticleYear
Cyclopropane-based conformational restriction of GABA by a stereochemical diversity-oriented strategy: identification of an efficient lead for potent inhibitors of GABA transports.
    Bioorganic & medicinal chemistry, 2013, Sep-01, Volume: 21, Issue:17

    Topics: Animals; Anticonvulsants; Brain; Cyclopropanes; GABA Modulators; GABA Plasma Membrane Transport Prot

2013
Mitochondrial defects associated with β-alanine toxicity: relevance to hyper-beta-alaninemia.
    Molecular and cellular biochemistry, 2016, Volume: 416, Issue:1-2

    Topics: Animals; beta-Alanine; Disorders of Excessive Somnolence; Electron Transport Complex I; Embryo, Mamm

2016
[Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration].
    The Japanese journal of antibiotics, 2002, Volume: 55, Issue:3

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agent

2002
Neurotoxic effects of alpha-fluoro-beta-alanine (FBAL) and fluoroacetic acid (FA) on dogs.
    The Journal of toxicological sciences, 2004, Volume: 29, Issue:2

    Topics: Administration, Oral; Animals; beta-Alanine; Dogs; Fluoroacetates; Fluorouracil; Hyperesthesia; Male

2004
Hyper-beta-alaninemia associated with beta-aminoaciduria and gamma-aminobutyricaciduria, somnolence and seizures.
    The New England journal of medicine, 1966, 03-24, Volume: 274, Issue:12

    Topics: 4-Aminobutyrate Transaminase; Amino Acid Metabolism, Inborn Errors; beta-Alanine; Disorders of Exces

1966
Activating effects of homotaurine and taurine on corticoreticular epilepsy.
    Epilepsia, 1981, Volume: 22, Issue:2

    Topics: Animals; beta-Alanine; Cats; Electrodes, Implanted; Electroencephalography; gamma-Aminobutyric Acid;

1981
A case of fatal seizure and unconsciousness caused by panipenem/betamipron.
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1998, Volume: 72, Issue:6

    Topics: Aged; Aged, 80 and over; beta-Alanine; Drug Therapy, Combination; Fatal Outcome; Female; Humans; Sei

1998
An experimental model to investigate disinhibitory mechanisms in penicillin epileptogenesis.
    Electroencephalography and clinical neurophysiology. Supplement, 1978, Issue:34

    Topics: Animals; beta-Alanine; Cats; gamma-Aminobutyric Acid; Glycine; Homocysteine; Iontophoresis; Neurotra

1978
Effects of glycine and other inhibitory amino acid neurotransmitters on strychnine convulsive threshold in mice.
    Veterinary and human toxicology, 1985, Volume: 27, Issue:2

    Topics: Alanine; Animals; beta-Alanine; Diazepam; Dose-Response Relationship, Drug; Glycine; Male; Mice; Mic

1985