carcinine has been researched along with Seizures in 2 studies
carcinine: structure
carcinine : A beta-alanine derivative that is the amide obtained by formal condensation of the carboxy group of beta-alanine with the primary amino group of histamine.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The kindling seizure was induced by ip injection with subconvulsant dose of pentylenetetrazole every 48 h." | 1.32 | [Effect of alahistidine on brain histamine content and seizure development]. ( Chen, Z; Hu, WW; Jin, CL; Sakurai, E; Xu, LS; Yanai, K, 2004) |
| "2 Carcinine was highly selective for the histamine H3 receptor over H1 or H2 receptor (Ki (microM)=0." | 1.32 | Pharmacological effects of carcinine on histaminergic neurons in the brain. ( Chen, Z; Hu, W; Jin, C; Kato, M; Kiso, Y; Sakurai, E; Watanabe, T; Wei, E; Yanai, K, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, WW | 1 |
| Chen, Z | 2 |
| Xu, LS | 1 |
| Jin, CL | 1 |
| Sakurai, E | 2 |
| Yanai, K | 2 |
| Hu, W | 1 |
| Jin, C | 1 |
| Kiso, Y | 1 |
| Kato, M | 1 |
| Watanabe, T | 1 |
| Wei, E | 1 |
2 other studies available for carcinine and Seizures
| Article | Year |
|---|---|
[Effect of alahistidine on brain histamine content and seizure development].
Topics: Animals; Brain Chemistry; Carnosine; Histamine; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley | 2004 |
Pharmacological effects of carcinine on histaminergic neurons in the brain.
Topics: Animals; Avoidance Learning; Brain; Carnosine; Convulsants; Dopamine; Histamine; Histidine Decarboxy | 2004 |