epinastine has been researched along with Seizures in 2 studies
epinastine: RN given refers parent cpd
epinastine : A benzazepine that is 6,11-dihydro-5H-dibenzo[b,e]azepine in which the azepine ring is fused to the e side of 4,5-dihydro-1H-imidazol-2-amine.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The centrally acting histamine H1 antagonists including pyrilamine (mepyramine) and ketotifen showed an acceleration in the rate of electrical stimulation to develop fully kindled convulsive seizures." | 3.69 | Centrally acting histamine H1 antagonists promote the development of amygdala kindling in rats. ( Iinuma, K; Onodera, K; Sato, M; Watanabe, T; Yokoyama, H, 1996) |
| "In this study, electroconvulsion was induced by stimulating rats using ear-clip electrodes, and the durations of electroencephalogram (EEG) seizure, tonic extensor (TE) seizure and clonic (CL) seizure induced by maximal electroshock were measured." | 1.34 | Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats. ( Ago, J; Ishikawa, T; Kamei, C; Matsumoto, N; Murakami, A; Rahman, A; Takechi, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishikawa, T | 1 |
| Takechi, K | 1 |
| Rahman, A | 1 |
| Ago, J | 1 |
| Matsumoto, N | 1 |
| Murakami, A | 1 |
| Kamei, C | 1 |
| Yokoyama, H | 1 |
| Sato, M | 1 |
| Iinuma, K | 1 |
| Onodera, K | 1 |
| Watanabe, T | 1 |
2 other studies available for epinastine and Seizures
| Article | Year |
|---|---|
Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.
Topics: Administration, Oral; Animals; Animals, Suckling; Chlorpheniramine; Cyproheptadine; Dibenzazepines; | 2007 |
Centrally acting histamine H1 antagonists promote the development of amygdala kindling in rats.
Topics: Amygdala; Animals; Dibenzazepines; Electroencephalography; Histamine H1 Antagonists; Imidazoles; Ket | 1996 |