fluconazole has been researched along with Seizures in 9 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Patients receiving fluconazole had higher serum cyclosporine levels and more adverse neurologic events (headaches, tremors, or seizures in 13 fluconazole recipients compared with 3 placebo recipients; P = 0." | 5.09 | Prophylactic fluconazole in liver transplant recipients. A randomized, double-blind, placebo-controlled trial. ( Busuttil, RW; Pakrasi, A; Winston, DJ, 1999) |
| "Mortality was associated with Glasgow coma score (GCS) below 15 (adjusted Hazard ratio (aHR) 1." | 2.94 | Determinants of two-year mortality among HIV positive patients with Cryptococcal meningitis initiating standard antifungal treatment with or without adjunctive dexamethasone in Uganda. ( Anywaine, Z; Day, J; Ggayi, AB; Kaleebu, P; Kibengo, FM; Kitonsa, J; Kiwanuka, J; Mayanja, Y; Nikweri, Y; Nsubuga, R; Onyango, M, 2020) |
| "Fluconazole can increase phenytoin serum concentrations leading to toxicity." | 2.39 | Fluconazole-induced symptomatic phenytoin toxicity. ( Cadle, RM; Hamill, RJ; Rodriguez-Barradas, MC; Zenon, GJ, 1994) |
| "The incidence of coccidioidomycosis is increasing, and published pediatric experience is limited." | 1.43 | Coccidioidomycosis: Experience From a Children's Hospital in an Area of Endemicity. ( Dimitrova, D; Ross, L, 2016) |
| "He presented with headache, seizures, confusion, fever and left hemiparesis upon hospitalization in 2006 at Hospital São Marcos." | 1.40 | Cerebral aspergillosis in a patient with leprosy and diabetes: a case report. ( Bezerra, GF; da Silva, MA; Filho, WE; Nascimento, AC; Nascimento, Mdo D; Segundo, JB; Viana, GM; Vidal, FC, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Karakurt, A | 1 |
| Ozalp, M | 1 |
| Işik, S | 1 |
| Stables, JP | 1 |
| Dalkara, S | 1 |
| Kitonsa, J | 1 |
| Nsubuga, R | 1 |
| Mayanja, Y | 1 |
| Kiwanuka, J | 1 |
| Nikweri, Y | 1 |
| Onyango, M | 1 |
| Anywaine, Z | 1 |
| Ggayi, AB | 1 |
| Kibengo, FM | 1 |
| Kaleebu, P | 1 |
| Day, J | 1 |
| Segundo, JB | 1 |
| da Silva, MA | 1 |
| Filho, WE | 1 |
| Nascimento, AC | 1 |
| Vidal, FC | 1 |
| Bezerra, GF | 1 |
| Viana, GM | 1 |
| Nascimento, Mdo D | 1 |
| Dimitrova, D | 1 |
| Ross, L | 1 |
| Cartner, M | 1 |
| Holley, A | 1 |
| Allworth, A | 1 |
| Pham, LV | 1 |
| Quang, AT | 1 |
| Ton Nu, PA | 1 |
| Duc, TT | 1 |
| Thi, HN | 1 |
| Cadle, RM | 1 |
| Zenon, GJ | 1 |
| Rodriguez-Barradas, MC | 1 |
| Hamill, RJ | 1 |
| Winston, DJ | 1 |
| Pakrasi, A | 1 |
| Busuttil, RW | 1 |
| Matsumoto, K | 1 |
| Ueno, K | 1 |
| Yoshimura, H | 1 |
| Morii, M | 1 |
| Takada, M | 1 |
| Sawai, T | 1 |
| Mitsutake, K | 1 |
| Shibakawa, M | 1 |
1 review available for fluconazole and Seizures
| Article | Year |
|---|---|
Fluconazole-induced symptomatic phenytoin toxicity.
Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Drug Interactions; Fluconazole; Humans; Male; | 1994 |
2 trials available for fluconazole and Seizures
| Article | Year |
|---|---|
Determinants of two-year mortality among HIV positive patients with Cryptococcal meningitis initiating standard antifungal treatment with or without adjunctive dexamethasone in Uganda.
Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Anti-Inflammatory Agents; Antifungal A | 2020 |
Prophylactic fluconazole in liver transplant recipients. A randomized, double-blind, placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Antifungal Agents; Cyclosporine; Female; Fluconazole; Headache; Humans; Liv | 1999 |
6 other studies available for fluconazole and Seizures
| Article | Year |
|---|---|
Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives.
Topics: Animals; Anti-Infective Agents; Anticonvulsants; Crystallography, X-Ray; Imidazoles; Molecular Confo | 2010 |
Cerebral aspergillosis in a patient with leprosy and diabetes: a case report.
Topics: Amphotericin B; Anticonvulsants; Antifungal Agents; Aspergillus fumigatus; Biopsy; Carbamazepine; Ce | 2014 |
Coccidioidomycosis: Experience From a Children's Hospital in an Area of Endemicity.
Topics: Adolescent; Antifungal Agents; Child; Child, Preschool; Coccidioidomycosis; Complement Fixation Test | 2016 |
False impressions from clear cerebrospinal fluid and a normal computed tomography scan: the pressure is still on for a diagnosis.
Topics: Adult; Antifungal Agents; Cerebrospinal Fluid; Confusion; Fluconazole; Humans; Immunocompetence; Mal | 2008 |
Cladophialophora bantiana and Candida albicans mixed infection in cerebral abscess of an HIV-negative patient.
Topics: Adult; Antifungal Agents; Brain; Brain Abscess; Brain Neoplasms; Candida albicans; Diagnosis, Differ | 2008 |
Fluconazole-induced convulsions at serum trough concentrations of approximately 80 microg/mL.
Topics: Aged; Antifungal Agents; Candidiasis; Drug Administration Schedule; Female; Fluconazole; Humans; Mal | 2000 |