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chloramphenicol and Seizures

chloramphenicol has been researched along with Seizures in 28 studies

Amphenicol: Chloramphenicol and its derivatives.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
") seizure prophylactic dose of fosphenytoin (18 mg kg-1 phenytoin sodium equivalents) were concomitantly administered to 15 African children with malaria."5.10Phenytoin pharmacokinetics and clinical effects in African children following fosphenytoin and chloramphenicol coadministration. ( Kokwaro, GO; Muchohi, SN; Newton, CR; Ogutu, BR; Otieno, GO, 2002)
"A 20 year old woman was admitted to our Department 15 days after the onset of typhoid fever treated with chloramphenicol."3.69Thrombosis of cerebral veins dural sinuses after paratyphi. ( Antonelli, M; Argenta, M; Bozzao, L; Inghilleri, M; Manfredi, M; Marchetti, P; Pedace, F, 1995)
"Chloramphenicol has little ototoxic potential when administered systemically in humans."2.36Ototoxic drugs and noise. ( Brown, RD; Glenn, DW; Henley, CM; Hodges, KB; Jobe, JC; Kupetz, SA; Penny, JE, 1981)
"The presence of convulsions before admission or at any time in the illness, coma on admission, and a history of illness of more than 3 days duration prior to admission were strongly associated with death."1.28Purulent meningitis in children: outcome using a standard management regimen with chloramphenicol. ( Tefuarani, N; Vince, JD, 1992)
"Six cats with stable seizure thresholds were treated with 150 mg/kg of chloramphenicol or its cogener, thiamphenicol, at 12-h intervals over a 30-h period."1.27Effects of protein synthesis inhibitors on sleep and amygdala-kindled seizure thresholds in cats. ( Belsito, O; Bowersox, SS; Shouse, MN, 1984)
"1, 1972, to July 1, 1975, with haemophilus meningitis were reviewed."1.26Haemophilus meningitis in Portsmouth. ( McLaughlin, S; Ware, SJ, 1978)
"One hundred and fifty cases of typhoid in infants and young children are reported."1.25Typhoid fever in young children. ( Mulligan, TO, 1971)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199024 (85.71)18.7374
1990's2 (7.14)18.2507
2000's2 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ogutu, BR1
Newton, CR1
Muchohi, SN1
Otieno, GO1
Kokwaro, GO1
HUMBERT, G1
DESPEIGNES, J1
COTTON, JB1
YU, J1
LACY, GM1
CONWAY, H1
Belsito, O1
Shouse, MN2
Bowersox, SS2
Kessler, DL1
Smith, AL1
Woodrum, DE1
Brown, RD1
Penny, JE1
Henley, CM1
Hodges, KB1
Kupetz, SA1
Glenn, DW1
Jobe, JC1
Inghilleri, M1
Pedace, F1
Argenta, M1
Marchetti, P1
Antonelli, M1
Bozzao, L1
Manfredi, M1
Koie, H1
Kurotobi, EN1
Sakai, T1
Cadoz, M1
Denis, F1
Chiron, JP1
Sow, A1
Diop Mar, I1
Ware, SJ1
McLaughlin, S1
Hambleton, G1
Davies, PA1
Duggan, MB1
Beyer, L1
Feigin, RD1
Stechenberg, BW1
Chang, MJ1
Dunkle, LM1
Wong, ML1
Palkes, H1
Dodge, PR1
Davis, H1
Tefuarani, N1
Vince, JD1
Easton, DM1
Estcourt, PG1
Brimblecombe, FS1
Burgess, W1
Hass, L1
Kurtz, JB1
Waitsuk, P1
Zakariás, S1
Becuş, T1
Gáspár, S1
Strangert, K1
Osuntokun, BO1
Bademosi, O1
Ogunremi, K1
Wright, SG1
Guckian, JC1
Siegenthaler, W1
Vetter, W1
Stiel, D1
Siegenthaler, G1
Lorber, J1
Al-Hachim, GM1
Al-Baker, A1
Scragg, J1
Rubidge, C1
Wallace, HL1
von Wasielewski, E1
Bredehorst, HG1
Mulligan, TO1
Kienitz, M1
von Landwüst, B1

Reviews

4 reviews available for chloramphenicol and Seizures

ArticleYear
Ototoxic drugs and noise.
    Ciba Foundation symposium, 1981, Volume: 85

    Topics: Acoustic Stimulation; Animals; Central Nervous System; Chloramphenicol; Cochlea; Cochlear Microphoni

1981
Bacterial meningitis. Some aspects of diagnosis and treatment.
    Archives of disease in childhood, 1975, Volume: 50, Issue:9

    Topics: Ampicillin; Bacterial Infections; Brain Edema; Child, Preschool; Chloramphenicol; Cloxacillin; Genta

1975
Typhoid fever in African and Indian children in Durban.
    Archives of disease in childhood, 1969, Volume: 44, Issue:233

    Topics: Africa, Southern; Anemia, Hemolytic; Aphasia; Arthritis; Ataxia; Cardiovascular Diseases; Carrier St

1969
[Significant side effects of antibiotics].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1971, Volume: 77

    Topics: Adolescent; Adult; Aged; Animals; Anti-Bacterial Agents; Cephalosporins; Child; Child, Preschool; Ch

1971

Trials

2 trials available for chloramphenicol and Seizures

ArticleYear
Phenytoin pharmacokinetics and clinical effects in African children following fosphenytoin and chloramphenicol coadministration.
    British journal of clinical pharmacology, 2002, Volume: 54, Issue:6

    Topics: Anti-Bacterial Agents; Anticonvulsants; Area Under Curve; Cefotaxime; Child, Preschool; Chlorampheni

2002
Prospective evaluation of treatment of Hemophilus influenzae meningitis.
    The Journal of pediatrics, 1976, Volume: 88, Issue:4 Pt 1

    Topics: Adolescent; Ampicillin; Antibodies, Bacterial; Antigens, Bacterial; Child; Child, Preschool; Chloram

1976

Other Studies

22 other studies available for chloramphenicol and Seizures

ArticleYear
["LISTERIA MONOCYTOGENES" MENINGITIS IN ADULTS. APROPOS OF 4 CASES].
    Journal de medecine de Lyon, 1964, May-05, Volume: 45

    Topics: Anti-Bacterial Agents; Bacteriological Techniques; Cerebrospinal Fluid; Chloramphenicol; Colistin; C

1964
NEONATAL MENINGITIS: PATHOGENESIS, DIAGNOSIS, MANAGEMENT, SEQUELAE.
    Clinical pediatrics, 1965, Volume: 4

    Topics: Adrenal Cortex Hormones; Ampicillin; Cerebrospinal Fluid Proteins; Chloramphenicol; Deafness; Diagno

1965
RECOVERY AFTER MENINGITIS WITH CONVULSIONS AND PARALYSIS FOLLOWING RHINOPLASTY: CAUSE FOR PAUSE; REPORT OF A CASE.
    Plastic and reconstructive surgery, 1965, Volume: 36

    Topics: Chloramphenicol; Drug Therapy; Meningitis; Methicillin; Nose; Nose Deformities, Acquired; Paralysis;

1965
Effects of protein synthesis inhibitors on sleep and amygdala-kindled seizure thresholds in cats.
    Behavioral and neural biology, 1984, Volume: 41, Issue:2

    Topics: Amygdala; Animals; Cats; Chloramphenicol; Disease Susceptibility; Kindling, Neurologic; Seizures; Sl

1984
Chloramphenicol toxicity in a neonate treated with exchange transfusion.
    The Journal of pediatrics, 1980, Volume: 96, Issue:1

    Topics: Anti-Bacterial Agents; Blood Transfusion; Chloramphenicol; Escherichia coli Infections; Female; Huma

1980
Effects of protein synthesis inhibitors on sleep and seizure susceptibility in kindled and nonkindled cats.
    Behavioral and neural biology, 1982, Volume: 35, Issue:4

    Topics: Animals; Brain; Cats; Chloramphenicol; Dose-Response Relationship, Drug; Evoked Potentials; Female;

1982
Thrombosis of cerebral veins dural sinuses after paratyphi.
    Italian journal of neurological sciences, 1995, Volume: 16, Issue:4

    Topics: Adult; Cerebral Veins; Chloramphenicol; Female; Fever; Humans; Magnetic Resonance Imaging; Seizures;

1995
Double-chambered right ventricle in a dog.
    The Journal of veterinary medical science, 2000, Volume: 62, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Chloramphenicol; Dog Disea

2000
[The prognosis and treatment of pneumococcal meningitis in Africa. 402 cases (author's transl)].
    La Nouvelle presse medicale, 1979, Feb-17, Volume: 8, Issue:8

    Topics: Adolescent; Adult; Africa; Age Factors; Aged; Anemia, Sickle Cell; Antigens, Bacterial; Cerebrospina

1979
Haemophilus meningitis in Portsmouth.
    Lancet (London, England), 1978, Jul-22, Volume: 2, Issue:8082

    Topics: Age Factors; Child; Child, Preschool; Chloramphenicol; England; Female; Humans; Infant; Male; Mening

1978
Enteric fever in young Yoruba children.
    Archives of disease in childhood, 1975, Volume: 50, Issue:1

    Topics: Age Factors; Anemia; Arthritis, Infectious; Blood Transfusion; Child, Preschool; Chloramphenicol; Di

1975
Purulent meningitis in children: outcome using a standard management regimen with chloramphenicol.
    Annals of tropical paediatrics, 1992, Volume: 12, Issue:4

    Topics: Bacteria; Child; Child, Preschool; Chloramphenicol; Humans; Infant; Infant, Newborn; Meningitis, Bac

1992
Outbreak of meningococcal disease in Devon.
    British medical journal, 1974, Mar-16, Volume: 1, Issue:5906

    Topics: Adolescent; Adult; Arthropathy, Neurogenic; Blood; Central Nervous System Diseases; Cerebrospinal Fl

1974
[Clinical contributions to the problem of allergic encephalopathies].
    Studii si cercetari de neurologie, 1969, Volume: 14, Issue:3

    Topics: Adult; Brain Diseases; Child; Chloramphenicol; Drug Eruptions; Drug Hypersensitivity; Dysentery; Fac

1969
Clinical course and prognosis of whooping-cough in Swedish children during the first six months of life. A study of hospitalized patients 1958-67.
    Scandinavian journal of infectious diseases, 1970, Volume: 2, Issue:1

    Topics: Age Factors; Apnea; Body Weight; Bordetella Infections; Bordetella pertussis; Bronchitis; Bronchopne

1970
Neuropsychiatric manifestations of typhoid fever in 959 patients.
    Archives of neurology, 1972, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chloramphenicol; Female; Humans; Infant; Male; Men

1972
Complications of antimicrobial therapy.
    American family physician, 1973, Volume: 8, Issue:1

    Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cephalosporins; Chloramphenicol; Drug Hypersensitivity;

1973
[The side-effects of the therapy of chronic lung diseases with antibiotics].
    Respiration; international review of thoracic diseases, 1970, Volume: 27

    Topics: Ampicillin; Anemia, Aplastic; Child, Preschool; Chloramphenicol; Chronic Disease; Drug Hypersensitiv

1970
Personal method of the treatment of Haemophilus influenzai meningitis in children.
    Neuropadiatrie, 1974, Volume: 5, Issue:4

    Topics: Ampicillin; Child; Child, Preschool; Chloramphenicol; Drug Therapy, Combination; Follow-Up Studies;

1974
The prenatal effect of chloramphenicol on the postnatal development of mice.
    Neuropharmacology, 1974, Volume: 13, Issue:4

    Topics: Administration, Oral; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Central N

1974
Typhoid fever in young children.
    British medical journal, 1971, Dec-11, Volume: 4, Issue:5788

    Topics: Age Factors; Anemia; Child; Child, Preschool; Chloramphenicol; Diarrhea; Female; Fever; Humans; Infa

1971
[Comments on the suitability of rectal chloramphenical therapy in bacterial infections during childhood].
    Monatsschrift fur Kinderheilkunde, 1967, Volume: 115, Issue:9

    Topics: Age Factors; Bronchitis; Child; Child, Preschool; Chloramphenicol; Eczema; Female; Fever; Humans; In

1967