clonidine has been researched along with Seizures in 78 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of drugs affecting GABA and glutamic acid receptors on theophylline-induced seizures were investigated in mice." | 7.70 | Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice. ( Amabeoku, GJ, 1999) |
| "The effects of muscimol, amino-oxyacetic acid (AOAA), diamino-N-butyric acid (DABA), bicuculline, picrotoxin, diazepam and phenobarbitone on the protective effect of clonidine against pentylenetetrazol-induced seizures were studied in mice." | 7.69 | gamma Aminobutyric acid mediation of the anticonvulsant effect of clonidine on pentylenetetrazol-induced seizures in mice. ( Amabeoku, G; Bwakura, E; Chikuni, O, 1994) |
| " The effects of some noradrenergic agents on seizures induced by strychnine were investigated in mice." | 7.69 | Strychnine-induced seizures in mice: the role of noradrenaline. ( Amabeoku, G; Chandomba, R, 1994) |
| "The influence of some noradrenergic, 5-hydroxytryptaminergic and cholinergic agents on imipramine-induced seizures were investigated in mice." | 7.68 | The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice. ( Amabeoku, GJ, 1993) |
| "We investigated in rats whether alterations in noradrenergic function caused by 6-hydroxydopamine or alpha- and beta-adrenoceptor agonists and antagonists would modify the susceptibility of the brain to electroencephalographic seizures induced by intrahippocampal infusion of quinolinic acid." | 7.67 | Norepinephrine modulates seizures induced by quinolinic acid in rats: selective and distinct roles of alpha-adrenoceptor subtypes. ( Samanin, R; Tullii, M; Vezzani, A; Wu, HQ, 1987) |
| "Injections of 5,7-dihydroxytryptamine (5,7-DHT) in the rat ventromedial tegmentum, which depleted forebrain serotonin, and of 6-hydroxydopamine in the dorsal noradrenergic bundle, which caused a marked reduction of forebrain noradrenaline, intensified pentylenetetrazol (PTZ)-induced seizures." | 7.67 | Evidence that the dorsal raphe area is involved in the effect of clonidine against pentylenetetrazole-induced seizures in rats. ( Bendotti, C; Lazarova, M; Samanin, R, 1984) |
| "10 mg/kg yohimbine significantly reduced the latency to the first convulsion of rats treated with 90 mg/kg pentylenetetrazol (PTZ) and markedly increased the number of animals showing generalized strong clonic seizures and dying within 1 h." | 7.66 | Potentiation by yohimbine of pentylenetetrazol-induced seizures in rats: role of alpha 2 adrenergic receptors. ( Lazarova, M; Samanin, R, 1983) |
| "5 mg/kg clonidine significantly increased the latency to the first convulsion and reduced tonic seizures and mortality caused by pentylenetetrazol (PTZ), 90 mg/kg, administered subcutaneously to rats." | 7.66 | Serotonin mediation of the protective effect of clonidine against pentylenetetrazol-induced seizures in rats. ( Lazarova, M; Samanin, R, 1983) |
| "The results were: (1) CLON elevated seizure thresholds obtained once at the beginning and end of kindling, but only when compared to sham control values (needle insertion only) in the same animals; IDA significantly reduced thresholds." | 5.34 | The alpha2 adrenoreceptor agonist clonidine suppresses evoked and spontaneous seizures, whereas the alpha2 adrenoreceptor antagonist idazoxan promotes seizures in amygdala-kindled kittens. ( de Lanerolle, N; Farber, PR; Scordato, JC; Shouse, MN, 2007) |
| "Focal and convulsive seizure thresholds were evaluated 10-12 min postinfusion and compared to thresholds obtained during two interspersed control conditions (vehicle control = 1 microliter microinfusion of sterile saline; sham control = needle insertion only)." | 5.29 | The alpha 2-adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2-adrenoreceptor antagonist idazoxan promotes seizures in amygdala-kindled kittens: a comparison of amygdala and pontine microinfusion effects. ( Alcalde, O; Bier, M; Farber, PR; Langer, J; Moghimi, R; Richkind, M; Shouse, MN; Szymusiak, R, 1996) |
| " Since several pathophysiological phenomena are common for both ischemia and seizures, we have explored the effect of acute and chronic administration of the adenosine A3 receptor selective agonist IB-MECA (N6-(3-iodobenzyl) adenosine-5'-N-methylcarboxamide) prior to seizures induced by N-methyl-D-aspartate (NMDA), pentamethylenetetrazole, or electric shock." | 5.29 | The effects of adenosine A3 receptor stimulation on seizures in mice. ( Carter, MF; Deutsch, SI; Jacobson, KA; Lin, RC; Mastropaolo, J; Meshulam, Y; Von Lubitz, DK, 1995) |
| "Focal and convulsive seizure thresholds were evaluated 10-12 min post-infusion and compared to thresholds obtained during two, interspersed control conditions (vehicle control: 1 microliter microinfusion of sterile saline; sham control: needle insertion only)." | 5.29 | The alpha 2-agonist clonidine suppresses seizures, whereas the alpha 2-antagonist idazoxan promotes seizures--a microinfusion study in amygdala-kindled kittens. ( Alcalde, O; Bier, M; Langer, J; Richkind, M; Shouse, MN; Szymusiak, R, 1994) |
| "Focal and convulsive seizure thresholds were evaluated 10-12 min post-infusion and compared to thresholds obtained during two, interspersed control conditions (vehicle control = 1 microliter microinfusion of sterile saline; sham control = needle insertion only)." | 5.29 | The alpha 2 adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2 adrenoreceptor antagonist idazoxan promotes seizures: pontine microinfusion studies of amygdala-kindled kittens. ( Alcalde, O; Bier, M; Farber, PR; Langer, J; Moghimi, R; Richkind, M; Shouse, MN; Szymusiak, R, 1996) |
| "kainic acid were a decrease in noradrenaline and an increase in 5-hydroxyindoleacetic acid in the acute (3 h after kainic acid injection) suggesting strongly increased neurotransmitter turnover in noradrenergic and serotonergic neurons." | 5.27 | Alpha 2-adrenoceptors modulate kainic acid-induced limbic seizures. ( Baran, H; Hornykiewicz, O; Hörtnagl, H; Sapetschnig, G; Sperk, G, 1985) |
| "Yohimbine tended to decrease seizure-latency at all doses, but statistical significance (p less than 0." | 5.27 | The effect of clonidine and yohimbine on audiogenic seizures (AGS) in rats. ( Kolonen, S; Tacke, U, 1984) |
| "Adenosine has anticonvulsant effects in various models of seizures." | 3.80 | The role of alpha-2 adrenoceptors in the anticonvulsant effects of adenosine on pentylenetetrazole-induced seizure threshold in mice. ( Mansoori, E; Moezi, L; Niknahad, H; Shafaroodi, H, 2014) |
| "The effects of drugs affecting GABA and glutamic acid receptors on theophylline-induced seizures were investigated in mice." | 3.70 | Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice. ( Amabeoku, GJ, 1999) |
| "The effects of alpha-adrenoceptors agents on seizures induced by intraperitoneal administration of lidocaine (75 mg/kg) were studied in mice." | 3.70 | Tizanidine protects mice against convulsions induced by lidocaine: involvement of alpha 2-adrenoceptors. ( Altenburg, SP; Farah, MB, 1999) |
| "The effects of muscimol, amino-oxyacetic acid (AOAA), diamino-N-butyric acid (DABA), bicuculline, picrotoxin, diazepam and phenobarbitone on the protective effect of clonidine against pentylenetetrazol-induced seizures were studied in mice." | 3.69 | gamma Aminobutyric acid mediation of the anticonvulsant effect of clonidine on pentylenetetrazol-induced seizures in mice. ( Amabeoku, G; Bwakura, E; Chikuni, O, 1994) |
| "Selected examples from three series of isomeric (alkylthio)-1,2,4-triazoles were prepared and examined for anticonvulsant activity versus strychnine-, maximal-electroshock-, pentylenetetrazole-, and 3-mercaptopropionic-acid-induced seizures in mice." | 3.69 | 5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents. ( Dalton, CR; Dudley, MW; Kane, JM; Kehne, JH; Ketteler, HJ; McCloskey, TC; Miller, FP; Ogden, AM; Senyah, Y; Staeger, MA, 1994) |
| " The effects of some noradrenergic agents on seizures induced by strychnine were investigated in mice." | 3.69 | Strychnine-induced seizures in mice: the role of noradrenaline. ( Amabeoku, G; Chandomba, R, 1994) |
| "The influence of some noradrenergic, 5-hydroxytryptaminergic and cholinergic agents on imipramine-induced seizures were investigated in mice." | 3.68 | The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice. ( Amabeoku, GJ, 1993) |
| "Injections of 5,7-dihydroxytryptamine (5,7-DHT) in the rat ventromedial tegmentum, which depleted forebrain serotonin, and of 6-hydroxydopamine in the dorsal noradrenergic bundle, which caused a marked reduction of forebrain noradrenaline, intensified pentylenetetrazol (PTZ)-induced seizures." | 3.67 | Evidence that the dorsal raphe area is involved in the effect of clonidine against pentylenetetrazole-induced seizures in rats. ( Bendotti, C; Lazarova, M; Samanin, R, 1984) |
| "We investigated in rats whether alterations in noradrenergic function caused by 6-hydroxydopamine or alpha- and beta-adrenoceptor agonists and antagonists would modify the susceptibility of the brain to electroencephalographic seizures induced by intrahippocampal infusion of quinolinic acid." | 3.67 | Norepinephrine modulates seizures induced by quinolinic acid in rats: selective and distinct roles of alpha-adrenoceptor subtypes. ( Samanin, R; Tullii, M; Vezzani, A; Wu, HQ, 1987) |
| "5 mg/kg clonidine significantly increased the latency to the first convulsion and reduced tonic seizures and mortality caused by pentylenetetrazol (PTZ), 90 mg/kg, administered subcutaneously to rats." | 3.66 | Serotonin mediation of the protective effect of clonidine against pentylenetetrazol-induced seizures in rats. ( Lazarova, M; Samanin, R, 1983) |
| "10 mg/kg yohimbine significantly reduced the latency to the first convulsion of rats treated with 90 mg/kg pentylenetetrazol (PTZ) and markedly increased the number of animals showing generalized strong clonic seizures and dying within 1 h." | 3.66 | Potentiation by yohimbine of pentylenetetrazol-induced seizures in rats: role of alpha 2 adrenergic receptors. ( Lazarova, M; Samanin, R, 1983) |
| "The preferential alpha 2-noradrenergic agonist clonidine dose-relatedly increased the onset of seizures and mortality times, and decreased severity in rats treated with D,L-allylglycine." | 3.66 | Alpha-noradrenaline modulation of D,L-allylgycine seizures. ( Ashton, D; Wauquier, A, 1981) |
| "Seizures are reported to occur more frequently among children with diagnoses of autism and pervasive developmental disorder (PDD), and some reports indicate a frequency as high as 30%." | 2.71 | EEG sedation for children with autism. ( Castello, FV; Mehta, UC; Patel, I, 2004) |
| " While medications for ADHD are generally well-tolerated, there are common, although less severe, as well as rare but severe adverse events AEs during treatment with ADHD drugs." | 2.49 | Practitioner review: current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents. ( Banaschewski, T; Buitelaar, J; Coghill, D; Cortese, S; Danckaerts, M; Dittmann, RW; Graham, J; Holtmann, M; Sergeant, J; Taylor, E, 2013) |
| "The authors believe that diencephalic seizures can present with a spectrum of autonomic features, and treatment should be tailored with the appropriate pharmacologic blockade." | 2.40 | Sympathetic storms in a child with a midbrain glioma: a variant of diencephalic seizures. ( Conway, EJ; DaRosso, RC; Epstein, FJ; Goh, KY; Muszynski, CA, 1999) |
| "Using model of clonic seizure induced by intravenous pentylenetetrazole (PTZ) in male mice, we investigated whether α₂-adrenoceptors is involved in the effects of cannabinoids on the seizure threshold." | 1.39 | The role of α₂-adrenoceptors in the anti-convulsant effects of cannabinoids on pentylenetetrazole-induced seizure threshold in mice. ( Bahremand, A; Dehpour, AR; Moezi, L; Shafaroodi, H, 2013) |
| "The results were: (1) CLON elevated seizure thresholds obtained once at the beginning and end of kindling, but only when compared to sham control values (needle insertion only) in the same animals; IDA significantly reduced thresholds." | 1.34 | The alpha2 adrenoreceptor agonist clonidine suppresses evoked and spontaneous seizures, whereas the alpha2 adrenoreceptor antagonist idazoxan promotes seizures in amygdala-kindled kittens. ( de Lanerolle, N; Farber, PR; Scordato, JC; Shouse, MN, 2007) |
| "Posterior reversible encephalopathy syndrome (PRES) is an acronym that identifies a new clinico-neuroradiologic entity occurring in association with different conditions." | 1.33 | PRES: posterior or potentially reversible encephalopathy syndrome? ( Abbate, M; Ferlazzo, E; Granata, F; Mazzù, I; Musolino, R; Narbone, MC, 2006) |
| "The thresholds for the clonic seizures induced after intravenous administration of pentylenetetrazole (PTZ) or bicuculline were assessed in mice weighing 23-30 g." | 1.31 | The role of alpha2-adrenoceptors in the modulatory effects of morphine on seizure susceptibility in mice. ( Dehpour, AR; Homayoun, H; Khavandgar, S, 2002) |
| "Its efficacy and tolerance in treating withdrawal symptoms is, however, suboptimal." | 1.31 | Topiramate in opiate withdrawal. ( Besson, J; Cottier, AC; Zullino, DF, 2002) |
| "Focal and convulsive seizure thresholds were evaluated 10-12 min post-infusion and compared to thresholds obtained during two, interspersed control conditions (vehicle control: 1 microliter microinfusion of sterile saline; sham control: needle insertion only)." | 1.29 | The alpha 2-agonist clonidine suppresses seizures, whereas the alpha 2-antagonist idazoxan promotes seizures--a microinfusion study in amygdala-kindled kittens. ( Alcalde, O; Bier, M; Langer, J; Richkind, M; Shouse, MN; Szymusiak, R, 1994) |
| " Since several pathophysiological phenomena are common for both ischemia and seizures, we have explored the effect of acute and chronic administration of the adenosine A3 receptor selective agonist IB-MECA (N6-(3-iodobenzyl) adenosine-5'-N-methylcarboxamide) prior to seizures induced by N-methyl-D-aspartate (NMDA), pentamethylenetetrazole, or electric shock." | 1.29 | The effects of adenosine A3 receptor stimulation on seizures in mice. ( Carter, MF; Deutsch, SI; Jacobson, KA; Lin, RC; Mastropaolo, J; Meshulam, Y; Von Lubitz, DK, 1995) |
| "Pretreatment with clonidine changed neither cumulative convulsant doses (Group 1: 41." | 1.29 | Clonidine does not affect lidocaine seizure threshold in rats. ( Goto, H; Hirakawa, M; Yokoyama, M, 1993) |
| "Focal and convulsive seizure thresholds were evaluated 10-12 min postinfusion and compared to thresholds obtained during two interspersed control conditions (vehicle control = 1 microliter microinfusion of sterile saline; sham control = needle insertion only)." | 1.29 | The alpha 2-adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2-adrenoreceptor antagonist idazoxan promotes seizures in amygdala-kindled kittens: a comparison of amygdala and pontine microinfusion effects. ( Alcalde, O; Bier, M; Farber, PR; Langer, J; Moghimi, R; Richkind, M; Shouse, MN; Szymusiak, R, 1996) |
| "Focal and convulsive seizure thresholds were evaluated 10-12 min post-infusion and compared to thresholds obtained during two, interspersed control conditions (vehicle control = 1 microliter microinfusion of sterile saline; sham control = needle insertion only)." | 1.29 | The alpha 2 adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2 adrenoreceptor antagonist idazoxan promotes seizures: pontine microinfusion studies of amygdala-kindled kittens. ( Alcalde, O; Bier, M; Farber, PR; Langer, J; Moghimi, R; Richkind, M; Shouse, MN; Szymusiak, R, 1996) |
| "Treatment with tizanidine was effective in 60% of the patients; there were high correlations between spasticity before and after tizanidine administration and the severity of symptoms and also between the degree of improvement in spasticity and in that of the symptoms." | 1.28 | Development of a simple spasticity quantification method: effects of tizanidine on spasticity in patients with sequelae of cerebrovascular disease. ( Asanuma, M; Hirata, H; Ogawa, N; Ota, Z; Yamamoto, M; Yamawaki, Y, 1992) |
| "Pretreatment with reserpine had no effect on either the time to onset or duration of maximal dentate activation." | 1.28 | Cholinergic and adrenergic agents modify the initiation and termination of epileptic discharges in the dentate gyrus. ( Lothman, EW; Stringer, JL, 1991) |
| " The high dosage of chlordimeform and both dosages of lidocaine enhanced the rate of kindling development (mean sessions to stage 5 seizures = 8." | 1.28 | Enhanced susceptibility to kindling by chlordimeform may be mediated by a local anesthetic action. ( Gilbert, ME; Mack, CM, 1989) |
| "Yohimbine tended to decrease seizure-latency at all doses, but statistical significance (p less than 0." | 1.27 | The effect of clonidine and yohimbine on audiogenic seizures (AGS) in rats. ( Kolonen, S; Tacke, U, 1984) |
| "Though the convulsions looked similar to morphine-induced seizures, naloxone failed to antagonize these effects." | 1.27 | Possible mechanism of digoxin-induced convulsions. ( Kulkarni, SK; Mehta, AK, 1983) |
| "When the discharge became bilateral, generalized seizures were soon apparent." | 1.27 | Effect of clonidine on amygdala kindling in normal and 6-hydroxydopamine-pretreated rats. ( Giugno, L; McIntyre, DC, 1988) |
| "kainic acid were a decrease in noradrenaline and an increase in 5-hydroxyindoleacetic acid in the acute (3 h after kainic acid injection) suggesting strongly increased neurotransmitter turnover in noradrenergic and serotonergic neurons." | 1.27 | Alpha 2-adrenoceptors modulate kainic acid-induced limbic seizures. ( Baran, H; Hornykiewicz, O; Hörtnagl, H; Sapetschnig, G; Sperk, G, 1985) |
| "[3H]clonidine binding was increased in the brainstem of the mutants, and to a lesser extent in the cerebral cortex, while it was slightly diminished in the hypothalamic area." | 1.27 | Altered postnatal ontogeny of alpha 1- and alpha 2-adrenoceptor binding sites in the brain of a convulsive mutant mouse (quaking). ( Baumann, N; Graillot, C; Le Saux, F; Maurin, Y, 1985) |
| "However, the incidence of convulsions was increased by FLA-63 in rats pretreated with the catecholamine precursor L-dihydroxyphenylalanine." | 1.27 | Neuropharmacological modification of central catecholamines: effects on pinealectomy-induced convulsions. ( Blask, DE; Stockmeier, CA, 1986) |
| " Observed on four drug-induced behavior categories, it was found that both clonidine and propranolol attenuated the toxic effects of relatively low dose levels of digitoxin, while at higher digitoxin dose levels only propranolol was able to reduce significantly the ED50 and the LD50." | 1.26 | Effect of age, clonidine or propranolol on behavioral toxicity induced with digitoxin in mice. ( Felleman, VH; Palfai, T, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (46.15) | 18.7374 |
| 1990's | 22 (28.21) | 18.2507 |
| 2000's | 11 (14.10) | 29.6817 |
| 2010's | 8 (10.26) | 24.3611 |
| 2020's | 1 (1.28) | 2.80 |
| Authors | Studies |
|---|---|
| Kane, JM | 1 |
| Staeger, MA | 1 |
| Dalton, CR | 1 |
| Miller, FP | 1 |
| Dudley, MW | 1 |
| Ogden, AM | 1 |
| Kehne, JH | 1 |
| Ketteler, HJ | 1 |
| McCloskey, TC | 1 |
| Senyah, Y | 1 |
| Zhang, R | 1 |
| Tan, Z | 1 |
| Niu, J | 1 |
| Feng, HJ | 1 |
| Barzegar, M | 1 |
| Piri, R | 1 |
| Naghavi-Behzad, M | 1 |
| Ghasempour, M | 1 |
| Shafaroodi, H | 2 |
| Moezi, L | 2 |
| Bahremand, A | 2 |
| Dehpour, AR | 3 |
| Sevrez, C | 1 |
| Lavocat, MP | 1 |
| Mounier, G | 1 |
| Elefant, E | 1 |
| Magnin, S | 1 |
| Teyssier, G | 1 |
| Patural, H | 1 |
| Mansoori, E | 1 |
| Niknahad, H | 1 |
| Payandemehr, B | 1 |
| Ebrahimi, A | 1 |
| Nasrabady, SE | 1 |
| Rahimian, R | 1 |
| Bahremand, T | 1 |
| Sharifzadeh, M | 1 |
| Bamford, A | 1 |
| Crowe, BH | 1 |
| Hacohen, Y | 1 |
| Lin, JP | 1 |
| Clarke, A | 1 |
| Tudor-Williams, G | 1 |
| Sancho-Shimizu, V | 1 |
| Vincent, A | 1 |
| Lim, M | 1 |
| Pullaperuma, SP | 1 |
| Chachua, T | 1 |
| Bilanishvili, I | 1 |
| Khizanishvili, N | 1 |
| Nanobashvili, Z | 1 |
| Cortese, S | 1 |
| Holtmann, M | 1 |
| Banaschewski, T | 1 |
| Buitelaar, J | 1 |
| Coghill, D | 1 |
| Danckaerts, M | 1 |
| Dittmann, RW | 1 |
| Graham, J | 1 |
| Taylor, E | 1 |
| Sergeant, J | 1 |
| Homayoun, H | 1 |
| Khavandgar, S | 1 |
| Zullino, DF | 1 |
| Cottier, AC | 1 |
| Besson, J | 1 |
| Mehta, UC | 1 |
| Patel, I | 1 |
| Castello, FV | 1 |
| Szot, P | 1 |
| Lester, M | 1 |
| Laughlin, ML | 1 |
| Palmiter, RD | 1 |
| Liles, LC | 1 |
| Weinshenker, D | 1 |
| Ahmed, SU | 1 |
| Vallejo, R | 1 |
| Hord, ED | 1 |
| Mendhekar, DN | 1 |
| Bordes, M | 1 |
| Cros, AM | 1 |
| Narbone, MC | 1 |
| Musolino, R | 1 |
| Granata, F | 1 |
| Mazzù, I | 1 |
| Abbate, M | 1 |
| Ferlazzo, E | 1 |
| Shouse, MN | 4 |
| Scordato, JC | 1 |
| Farber, PR | 3 |
| de Lanerolle, N | 1 |
| Behrman, A | 1 |
| Goertemoeller, S | 1 |
| Feron, FJ | 1 |
| Hendriksen, JG | 1 |
| Nicolai, J | 1 |
| Vles, JS | 1 |
| Yue, W | 1 |
| Zhang, SS | 1 |
| Homeida, AM | 2 |
| Cooke, RG | 2 |
| Ashton, D | 2 |
| Wauquier, A | 2 |
| Papanicolaou, J | 1 |
| Summers, RJ | 1 |
| Vajda, FJ | 1 |
| Louis, WJ | 1 |
| Maurin, Y | 4 |
| Arbilla, S | 1 |
| Dedek, J | 1 |
| Lee, CR | 1 |
| Baumann, N | 4 |
| Langer, SZ | 1 |
| Lazarova, M | 3 |
| Samanin, R | 4 |
| Kulkarni, SK | 2 |
| Mehta, AK | 1 |
| Bendotti, C | 1 |
| Tacke, U | 1 |
| Kolonen, S | 1 |
| Pappas, BA | 1 |
| Walsh, P | 1 |
| Blum, K | 1 |
| Briggs, AH | 1 |
| DeLallo, L | 1 |
| Leysen, JE | 1 |
| Nutt, DJ | 1 |
| Smith, SL | 1 |
| Heal, DJ | 2 |
| Palfai, T | 1 |
| Felleman, VH | 1 |
| Akagi, H | 1 |
| Bowdler, JM | 1 |
| Green, AR | 1 |
| Von Lubitz, DK | 1 |
| Carter, MF | 1 |
| Deutsch, SI | 1 |
| Lin, RC | 1 |
| Mastropaolo, J | 1 |
| Meshulam, Y | 1 |
| Jacobson, KA | 1 |
| Genkova-Papazova, M | 1 |
| Lazarova-Bakarova, M | 1 |
| Petkov, VD | 1 |
| Pelletier, MR | 1 |
| Corcoran, ME | 1 |
| Bier, M | 3 |
| Langer, J | 3 |
| Alcalde, O | 3 |
| Richkind, M | 3 |
| Szymusiak, R | 3 |
| Amabeoku, G | 2 |
| Chandomba, R | 1 |
| Chikuni, O | 1 |
| Bwakura, E | 1 |
| Amabeoku, GJ | 2 |
| Yokoyama, M | 1 |
| Hirakawa, M | 1 |
| Goto, H | 1 |
| Moghimi, R | 2 |
| Cantwell, DP | 1 |
| Swanson, J | 1 |
| Connor, DF | 1 |
| Altenburg, SP | 1 |
| Farah, MB | 1 |
| Denizbaşi, A | 1 |
| Berkman, K | 1 |
| Ozyazgan, S | 1 |
| Eşkazan, E | 1 |
| Enginar, N | 1 |
| Yamantürk, P | 1 |
| Nurten, A | 1 |
| Koyuncuoğlu, H | 1 |
| Goh, KY | 1 |
| Conway, EJ | 1 |
| DaRosso, RC | 1 |
| Muszynski, CA | 1 |
| Epstein, FJ | 1 |
| Oishi, R | 1 |
| Suenaga, N | 1 |
| Hidaka, T | 1 |
| Fukuda, T | 1 |
| Conner, CS | 1 |
| Watanabe, AS | 1 |
| Chermat, R | 1 |
| Lachapelle, F | 1 |
| Simon, P | 2 |
| Roberts, DC | 1 |
| McCaughran, JA | 1 |
| Fibiger, HC | 1 |
| Dadkar, VN | 1 |
| Dahanukar, SA | 1 |
| Sheth, UK | 1 |
| Mitrovic, N | 1 |
| Le Saux, F | 2 |
| Gioanni, H | 1 |
| Gioanni, Y | 1 |
| Besson, MJ | 1 |
| Ogawa, N | 1 |
| Asanuma, M | 1 |
| Hirata, H | 1 |
| Ota, Z | 1 |
| Yamawaki, Y | 1 |
| Yamamoto, M | 1 |
| Ueno, K | 1 |
| Miyai, K | 1 |
| Mitsuzane, K | 1 |
| Stringer, JL | 1 |
| Lothman, EW | 1 |
| Popoli, P | 1 |
| Pezzola, A | 2 |
| Scotti de Carolis, A | 2 |
| Gilbert, ME | 1 |
| Mack, CM | 1 |
| Kunchandy, J | 1 |
| McIntyre, DC | 1 |
| Giugno, L | 1 |
| Pohl, M | 1 |
| Mares, P | 1 |
| Picková, M | 1 |
| Passarelli, F | 1 |
| Das, M | 1 |
| Chauhan, SP | 1 |
| Ganguly, DK | 1 |
| Baran, H | 1 |
| Sperk, G | 1 |
| Hörtnagl, H | 1 |
| Sapetschnig, G | 1 |
| Hornykiewicz, O | 1 |
| Graillot, C | 2 |
| Wu, HQ | 1 |
| Tullii, M | 1 |
| Vezzani, A | 1 |
| Jazrawi, SP | 1 |
| Horton, RW | 1 |
| Stockmeier, CA | 1 |
| Blask, DE | 1 |
| Siegel, EG | 1 |
| Bonfiglio, JF | 1 |
| Ritschel, WA | 1 |
| Fant, W | 1 |
| Boissier, JR | 1 |
| Zebrowska-Lupina, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Therapeutic Use of Repetitive Transcranial Magnetic Stimulation (rTMS) in Pediatric Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Cohorts (ADHD): a Randomized, Sham-controlled Study.[NCT06069323] | 80 participants (Anticipated) | Interventional | 2023-06-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for clonidine and Seizures
| Article | Year |
|---|---|
Practitioner review: current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents.
Topics: Adolescent; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Blood Pressure | 2013 |
[Inhalation induction with sevoflurane in paediatrics: what is new?].
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Drug Synergism; | 2006 |
Sympathetic storms in a child with a midbrain glioma: a variant of diencephalic seizures.
Topics: Anticonvulsants; Astrocytoma; Autonomic Nervous System Diseases; Brain Neoplasms; Child; Clonidine; | 1999 |
Clonidine overdose: a review.
Topics: Adolescent; Adult; Cardiovascular Diseases; Child, Preschool; Clonidine; Coma; Female; Humans; Hypot | 1979 |
2 trials available for clonidine and Seizures
| Article | Year |
|---|---|
Clonidine Sedation Effects in Children During Electroencephalography.
Topics: Child; Child, Preschool; Clonidine; Conscious Sedation; Consciousness; Electroencephalography; Femal | 2017 |
EEG sedation for children with autism.
Topics: Autistic Disorder; Child Development Disorders, Pervasive; Clonidine; Electroencephalography; Humans | 2004 |
72 other studies available for clonidine and Seizures
| Article | Year |
|---|---|
5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents.
Topics: Animals; Anticonvulsants; Cerebellum; Cerebral Cortex; Chlorides; Electroshock; Flumazenil; Male; Mi | 1994 |
Adrenergic α2 receptors are implicated in seizure-induced respiratory arrest in DBA/1 mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Atomoxetine Hydrochlori | 2021 |
The role of α₂-adrenoceptors in the anti-convulsant effects of cannabinoids on pentylenetetrazole-induced seizure threshold in mice.
Topics: Animals; Anticonvulsants; Arachidonic Acids; Cannabinoids; Clonidine; Dose-Response Relationship, Dr | 2013 |
[Transplacental or breast milk intoxication to clonidine: a case of neonatal hypotonia and drowsiness].
Topics: Clonidine; Consciousness Disorders; Diagnosis, Differential; Female; Humans; Hypertension, Pregnancy | 2014 |
The role of alpha-2 adrenoceptors in the anticonvulsant effects of adenosine on pentylenetetrazole-induced seizure threshold in mice.
Topics: Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic | 2014 |
Protective effects of lithium chloride on seizure susceptibility: Involvement of α2-adrenoceptor.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Benzofurans; | 2015 |
Pediatric Herpes Simplex Virus Encephalitis Complicated by N-Methyl-D-aspartate Receptor Antibody Encephalitis.
Topics: Acyclovir; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Antiviral Agents; Autoantibodies; Clonid | 2015 |
Noradrenergic modulation of seizure activity.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; D | 2010 |
The role of alpha2-adrenoceptors in the modulatory effects of morphine on seizure susceptibility in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Differential Threshold; | 2002 |
Topiramate in opiate withdrawal.
Topics: Adrenergic alpha-Agonists; Adult; Anticonvulsants; Clonidine; Female; Fructose; Heroin Dependence; H | 2002 |
The anticonvulsant and proconvulsant effects of alpha2-adrenoreceptor agonists are mediated by distinct populations of alpha2A-adrenoreceptors.
Topics: Adrenergic alpha-Agonists; Animals; Anticonvulsants; Autoreceptors; Clonidine; Convulsants; Guanfaci | 2004 |
Seizures after a Bier block with clonidine and lidocaine: is clonidine really the culprit?
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Clonidine; Drug Interactions; Humans; Lidoca | 2005 |
Clonidine-induced gynecomastia and hyperprolactinemia in a 6-year-old child.
Topics: Age Factors; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Comor | 2005 |
PRES: posterior or potentially reversible encephalopathy syndrome?
Topics: Adult; Anti-Inflammatory Agents; Anticonvulsants; Antihypertensive Agents; Brain; Brain Diseases; Cl | 2006 |
The alpha2 adrenoreceptor agonist clonidine suppresses evoked and spontaneous seizures, whereas the alpha2 adrenoreceptor antagonist idazoxan promotes seizures in amygdala-kindled kittens.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Animals, Newborn; Cats; | 2007 |
A sticky situation: toxicity of clonidine and fentanyl transdermal patches in pediatrics.
Topics: Accidents; Administration, Cutaneous; Analgesics, Opioid; Antihypertensive Agents; Clonidine; Coma; | 2007 |
New-onset seizures: a possible association with clonidine?
Topics: Adrenergic alpha-Agonists; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Cerebral | 2008 |
[Effects of clonidine and yohimbine on semicarbazide-induced convulsion and electroconvulsive shock].
Topics: Animals; Clonidine; Electroshock; Female; Hydroxydopamines; Male; Mice; Oxidopamine; Propranolol; Re | 1984 |
Pharmacological aspects of metaldehyde poisoning in mice.
Topics: Acetaldehyde; Animals; Brain; Clonidine; Diazepam; Female; Hydroxyindoleacetic Acid; Male; Mice; Mic | 1982 |
Alpha-noradrenaline modulation of D,L-allylgycine seizures.
Topics: Allylglycine; Animals; Clonidine; Glycine; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strain | 1981 |
The relationship between alpha 2-adrenoceptor selectivity and anticonvulsant effect in a series of clonidine-like drugs.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Clonidine; Female; Male; Pentylenetetrazole; Prazosin; Ra | 1982 |
Noradrenergic neurotransmission in the brain of a convulsive mutant mouse, differences between the cerebral cortex and the brain stem.
Topics: Animals; Brain; Brain Stem; Cerebral Cortex; Clonidine; Female; Male; Mice; Mice, Inbred C57BL; Mice | 1982 |
Potentiation by yohimbine of pentylenetetrazol-induced seizures in rats: role of alpha 2 adrenergic receptors.
Topics: Animals; Clonidine; Drug Synergism; Male; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, | 1983 |
Possible mechanism of digoxin-induced convulsions.
Topics: Animals; Calcium Chloride; Clonidine; Diazepam; Digoxin; Female; gamma-Aminobutyric Acid; Magnesium; | 1983 |
Evidence that the dorsal raphe area is involved in the effect of clonidine against pentylenetetrazole-induced seizures in rats.
Topics: 5,7-Dihydroxytryptamine; Animals; Anticonvulsants; Brain Chemistry; Brain Stem; Clonidine; Hydroxydo | 1984 |
The effect of clonidine and yohimbine on audiogenic seizures (AGS) in rats.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Clonidine; Norepinephrine; Rats; Seizures; Yohimbine | 1984 |
Behavioral comparison of pentylenetetrazol, clonidine, chlordiazepoxide and diazepam in infant rats.
Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Chlordiazepoxide; Clonidine; Diazepam; Mot | 1983 |
Clonidine enhancement of ethanol withdrawal in mice.
Topics: Animals; Clonidine; Drug Interactions; Ethanol; Humans; Mice; Mice, Inbred Strains; Pyrazoles; Seizu | 1983 |
Serotonin mediation of the protective effect of clonidine against pentylenetetrazol-induced seizures in rats.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Fenfluramine; Male; Metergoline; Methysergide; | 1983 |
Neurotransmitters and receptor binding in amygdaloid kindled rats: serotonergic and noradrenergic modulatory effects.
Topics: 5-Hydroxytryptophan; Amygdala; Animals; Brain; Clonidine; Dexetimide; Electric Stimulation; Male; Mi | 1980 |
Anti-convulsant activity of diazepam and clonidine on metaldehyde-induced seizures in mice: effects on brain gamma-amino butyric acid concentrations and monoamine oxidase activity.
Topics: Acetaldehyde; Animals; Brain Chemistry; Clonidine; Diazepam; Female; gamma-Aminobutyric Acid; Male; | 1982 |
Hypophysectomy does not prevent the enhanced monoamine-mediated behavioural responses following repeated electroconvulsive shocks.
Topics: Animals; Apomorphine; Biogenic Amines; Clonidine; Electroshock; Hypophysectomy; Male; Motor Activity | 1982 |
Effect of age, clonidine or propranolol on behavioral toxicity induced with digitoxin in mice.
Topics: Aging; Animals; Behavior, Animal; Clonidine; Digitoxin; Drug Interactions; Gait; Male; Mice; Postura | 1982 |
Repeated electroconvulsive shock attenuates clonidine-induced hypoactivity in rodents.
Topics: Animals; Behavior, Animal; Brain Chemistry; Clonidine; Dose-Response Relationship, Drug; Drug Intera | 1981 |
The effects of adenosine A3 receptor stimulation on seizures in mice.
Topics: Adenosine; Animals; Clonidine; Drug Interactions; Electroshock; Injections, Intraperitoneal; Male; M | 1995 |
The 5-HT2 receptor antagonist ketanserine prevents electroconvulsive shock- and clonidine-induced amnesia.
Topics: Amnesia; Animals; Avoidance Learning; Clonidine; Electroshock; Injections, Intraperitoneal; Ketanser | 1994 |
Infusions of alpha-2 noradrenergic agonists and antagonists into the amygdala: effects on kindling.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Am | 1993 |
The alpha 2-agonist clonidine suppresses seizures, whereas the alpha 2-antagonist idazoxan promotes seizures--a microinfusion study in amygdala-kindled kittens.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Amygdala; Animals; An | 1994 |
Strychnine-induced seizures in mice: the role of noradrenaline.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Disulfiram; Droxidopa; Idazoxan; Imipram | 1994 |
gamma Aminobutyric acid mediation of the anticonvulsant effect of clonidine on pentylenetetrazol-induced seizures in mice.
Topics: Animals; Clonidine; Disease Models, Animal; gamma-Aminobutyric Acid; Mice; Pentylenetetrazole; Seizu | 1994 |
The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice.
Topics: 5-Hydroxytryptophan; Acetylcholine; alpha-Methyltyrosine; Animals; Atropine; Clonidine; Dioxanes; Dr | 1993 |
Clonidine does not affect lidocaine seizure threshold in rats.
Topics: Animals; Blood Pressure; Carbon Dioxide; Clonidine; Dose-Response Relationship, Drug; Heart Rate; He | 1993 |
The alpha 2-adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2-adrenoreceptor antagonist idazoxan promotes seizures in amygdala-kindled kittens: a comparison of amygdala and pontine microinfusion effects.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Cats; Clonidine; Dioxane | 1996 |
The alpha 2 adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2 adrenoreceptor antagonist idazoxan promotes seizures: pontine microinfusion studies of amygdala-kindled kittens.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agon | 1996 |
Case study: adverse response to clonidine.
Topics: Adrenergic alpha-Agonists; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Fatal Ou | 1997 |
Tizanidine protects mice against convulsions induced by lidocaine: involvement of alpha 2-adrenoceptors.
Topics: Animals; Anticonvulsants; Behavior, Animal; Clonidine; Drug Interactions; Lidocaine; Male; Mice; Phe | 1999 |
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Cl | 1999 |
The effect of tizanidine on maximal electroshock seizures (MES) in mice.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Clonidine; Electroshoc | 1999 |
Scopolamine-induced convulsions in food given fasted mice: effects of clonidine and tizanidine.
Topics: Animals; Anticonvulsants; Clonidine; Fasting; Male; Mice; Scopolamine; Seizures | 1999 |
The role of alpha-adrenoceptors in the regulation of pentylenetetrazol convulsions in mice.
Topics: Animals; Clonidine; Hydroxydopamines; Male; Mice; Pentylenetetrazole; Phentolamine; Receptors, Adren | 1979 |
Anticonvulsant effect of yohimbine in quaking mice: antagonism by clonidine and prazosine.
Topics: Animals; Anticonvulsants; Clonidine; Male; Mice; Mice, Quaking; Phentolamine; Prazosin; Quinazolines | 1979 |
Behavioural effects of 6-hydroxydopamine-induced depletion of spinal noradrenaline.
Topics: Amphetamine; Animals; Brain Chemistry; Clonidine; Hydroxydopamines; Male; Motor Activity; Norepineph | 1979 |
Role of dopaminergic and noradrenergic mechanisms in Metrazole convulsions in mice.
Topics: Animals; Apomorphine; Benserazide; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Clonidine; | 1979 |
Distribution of [3H]clonidine binding sites in the brain of the convulsive mutant quaking mouse: a radioautographic analysis.
Topics: Animals; Autoradiography; Binding Sites; Brain; Clonidine; In Vitro Techniques; Kinetics; Male; Mice | 1992 |
Development of a simple spasticity quantification method: effects of tizanidine on spasticity in patients with sequelae of cerebrovascular disease.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Clonidine; Female; Humans; Male; Middle Aged; Musc | 1992 |
Phenytoin-tizanidine interaction.
Topics: Anticonvulsants; Biotransformation; Clonidine; Drug Interactions; Drug Monitoring; Female; Humans; M | 1991 |
Cholinergic and adrenergic agents modify the initiation and termination of epileptic discharges in the dentate gyrus.
Topics: Animals; Atropine; Clonidine; Electric Stimulation; Epilepsy; Hippocampus; Male; Parasympathomimetic | 1991 |
An EEG and behavioural study on the interactions of clonidine with phencyclidine and ketamine in rats.
Topics: Animals; Brain; Clonidine; Drug Interactions; Electroencephalography; Ketamine; Male; Muscle Tonus; | 1990 |
Enhanced susceptibility to kindling by chlordimeform may be mediated by a local anesthetic action.
Topics: Amidines; Amygdala; Anesthetics, Local; Animals; Chlorphenamidine; Clonidine; Electroencephalography | 1989 |
Modulatory effect of alpha 2 adrenoceptor agonists on Ro 5-4864-induced convulsions in rats and mice.
Topics: Animals; Anticonvulsants; Azepines; Benzodiazepinones; Brain; Clonidine; Convulsants; Guanfacine; Gu | 1987 |
Effect of clonidine on amygdala kindling in normal and 6-hydroxydopamine-pretreated rats.
Topics: Amygdala; Animals; Brain; Clonidine; Electrophysiology; Hydroxydopamines; Kindling, Neurologic; Male | 1988 |
Influence of clonidine on metrazol-induced seizures in young rats.
Topics: Animals; Clonidine; Male; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alp | 1987 |
Study on the anticonvulsant activity of clonidine against pentylenetetrazol-induced seizures in rats: pharmacological evidence of alpha 2-adrenoceptors mediation.
Topics: Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Clonidine; Electroencephalography; Male; Mot | 1986 |
Alpha 2-antagonistic effect of N-carbamoyl-2-(2,6-dichlorophenyl) acetamidine hydrochloride (LON-954).
Topics: Adrenergic alpha-Antagonists; Animals; Body Temperature; Clonidine; Dopamine Antagonists; Female; Gu | 1988 |
Alpha 2-adrenoceptors modulate kainic acid-induced limbic seizures.
Topics: Animals; Brain Chemistry; Clonidine; Diazepam; Haloperidol; Kainic Acid; Male; Metergoline; Prazosin | 1985 |
Altered postnatal ontogeny of alpha 1- and alpha 2-adrenoceptor binding sites in the brain of a convulsive mutant mouse (quaking).
Topics: Animals; Brain; Brain Chemistry; Clonidine; Dihydroalprenolol; Female; Male; Mice; Mice, Inbred C57B | 1985 |
Modulation of alpha 1-and alpha 2-adrenoceptor binding sites in the brain of audiogenic seizure susceptible mice (DBA/2J).
Topics: Acoustic Stimulation; Animals; Brain; Clonidine; Dihydroalprenolol; Female; Kinetics; Male; Mice; Mi | 1985 |
Norepinephrine modulates seizures induced by quinolinic acid in rats: selective and distinct roles of alpha-adrenoceptor subtypes.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Hippocampus; Hydroxydopamines; Male; Methoxami | 1987 |
Brain adrenoceptor binding sites in mice susceptible (DBA/2J) and resistant (C57 Bl/6) to audiogenic seizures.
Topics: Acoustic Stimulation; Animals; Binding Sites; Brain; Clonidine; Dihydroalprenolol; Disease Susceptib | 1986 |
Neuropharmacological modification of central catecholamines: effects on pinealectomy-induced convulsions.
Topics: alpha-Methyltyrosine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Catechol | 1986 |
Investigation of clonidine and lofexidine for the treatment of barbiturate withdrawal in mice.
Topics: Animals; Barbiturates; Clonidine; Male; Mice; Mice, Inbred DBA; Seizures; Substance Withdrawal Syndr | 1985 |
[Psychopharmacologic profile of prazepam].
Topics: Aggression; Animals; Avoidance Learning; Benzazepines; Clonidine; Cyclopropanes; Depression, Chemica | 1972 |