propranolol has been researched along with Seizures in 91 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effects of some noradrenergic agents on seizures induced by strychnine were investigated in mice." | 7.69 | Strychnine-induced seizures in mice: the role of noradrenaline. ( Amabeoku, G; Chandomba, R, 1994) |
| "The effects of some noradrenergic agents, phenobarbitone, diazepam and phenytoin on seizures produced by propranolol were investigated in mice." | 7.69 | Propranolol-induced seizures in mice: the role of noradrenaline. ( Amabeoku, GJ; Syce, JA, 1997) |
| "The effects of levodopa, apomorphine and 3,4-dihydroxyphenylserine (DOPS) on tonic seizures elicited by strychnine were investigated in mice." | 7.67 | Influence of levodopa, apomorphine and 3,4-dihydroxyphenylserine (DOPS) on strychnine-induced seizures in mice. ( Gamaniel, K; Osuide, G; Wambebe, C, 1984) |
| "The goal of this study was to test the hypothesis that phentolamine and propranolol premedication would affect tonus differently than clonus in pentylenetetrazol (PTZ)-induced tonic-clonic seizures in dogs." | 7.67 | Influence of phentolamine and propranolol on the length of tonus and clonus in pentylenetetrazol-induced seizures in dogs. ( Cunningham, JG; Stephenson, RB, 1984) |
| "The aim of this study was to determine the possible effect of propranolol, a beta-adrenoceptor blocker, on maximal electroshock seizures (MES) in mice." | 7.67 | The effect of propranolol on maximal electroshock seizures in mice. ( Akcasu, A; Akkan, AG; Eşkazan, E; Ozüner, Z; Yillar, DO, 1989) |
| "The tremorogenic effect of nicotine was studied in control rats and in rats withdrawn for 16-48 h from six to nine days' ethanol administration." | 7.67 | Ethanol withdrawal tremor potentiates the tremorogenic action of nicotine. ( Gothóni, P; Ikola, W, 1985) |
| "Severe hypoglycemia was common in infants aged >1 year, when PPL was used for ≥6 months." | 5.72 | Severe hypoglycemia in propranolol treatment for infantile hemangiomas. ( Baba, N; Kaneko, T; Kuwano, Y; Morimoto, A; Ozeki, M; Sasaki, S, 2022) |
| "Pretreatment with propranolol increased the time-to-seizure by 70% and practolol by 50% without altering gross lung appearance or lung wet wt/dry wt." | 5.27 | Beta adrenergic receptors and glucagon in seizures from exposure to oxygen at high pressure (OHP). ( Beckman, DL; Crittenden, DJ, 1983) |
| "kainic acid were a decrease in noradrenaline and an increase in 5-hydroxyindoleacetic acid in the acute (3 h after kainic acid injection) suggesting strongly increased neurotransmitter turnover in noradrenergic and serotonergic neurons." | 5.27 | Alpha 2-adrenoceptors modulate kainic acid-induced limbic seizures. ( Baran, H; Hornykiewicz, O; Hörtnagl, H; Sapetschnig, G; Sperk, G, 1985) |
| "Both patients experienced generalized seizures and had a transient intraventricular conduction defect on electrocardiogram." | 5.26 | Seizures and intraventricular conduction defect in propranolol poisoning. A report of two cases. ( Bock, J; Buiumsohn, A; Eisenberg, ES; Frishman, WH; Jacob, H; Rosen, N, 1979) |
| "The effects of some noradrenergic agents, phenobarbitone, diazepam and phenytoin on seizures produced by propranolol were investigated in mice." | 3.69 | Propranolol-induced seizures in mice: the role of noradrenaline. ( Amabeoku, GJ; Syce, JA, 1997) |
| " The effects of some noradrenergic agents on seizures induced by strychnine were investigated in mice." | 3.69 | Strychnine-induced seizures in mice: the role of noradrenaline. ( Amabeoku, G; Chandomba, R, 1994) |
| "Death from cocaine intoxication results from one or more of the multiple mechanisms including seizures, cardiovascular collapse, or apnea." | 3.68 | Acute cocaine toxicity: the effect of agents in non-seizure-induced death. ( Albertson, TE; Derlet, RW; Tseng, CC, 1993) |
| "The effects of levodopa, apomorphine and 3,4-dihydroxyphenylserine (DOPS) on tonic seizures elicited by strychnine were investigated in mice." | 3.67 | Influence of levodopa, apomorphine and 3,4-dihydroxyphenylserine (DOPS) on strychnine-induced seizures in mice. ( Gamaniel, K; Osuide, G; Wambebe, C, 1984) |
| "The aim of this study was to determine the possible effect of propranolol, a beta-adrenoceptor blocker, on maximal electroshock seizures (MES) in mice." | 3.67 | The effect of propranolol on maximal electroshock seizures in mice. ( Akcasu, A; Akkan, AG; Eşkazan, E; Ozüner, Z; Yillar, DO, 1989) |
| "The tremorogenic effect of nicotine was studied in control rats and in rats withdrawn for 16-48 h from six to nine days' ethanol administration." | 3.67 | Ethanol withdrawal tremor potentiates the tremorogenic action of nicotine. ( Gothóni, P; Ikola, W, 1985) |
| "The presenting symptoms, course, and treatment of 10 patients with severe theophylline toxicity (heart rate above 120, multifocal atrial tachycardia or premature ventricular contractions, hypotension, seizures) are described." | 3.67 | Severe theophylline toxicity. Role of conservative measures, antiarrhythmic agents, and charcoal hemoperfusion. ( Greenberg, A; Kroboth, PD; Piraino, BH; Weiss, J, 1984) |
| "The goal of this study was to test the hypothesis that phentolamine and propranolol premedication would affect tonus differently than clonus in pentylenetetrazol (PTZ)-induced tonic-clonic seizures in dogs." | 3.67 | Influence of phentolamine and propranolol on the length of tonus and clonus in pentylenetetrazol-induced seizures in dogs. ( Cunningham, JG; Stephenson, RB, 1984) |
| " The other cases published are: 1) 10 cases with oxprenolol (including 5 cases of coma and 4 deaths), 2) 9 cases with acebutolol (2 deaths) including 5 with studies of the kinetics of the product (1 personal case), 3) 7 cases with pindolol (no bradycardia, good prognosis), 4) 6 cases (1 personal) with metoprolol (4 cases of massive ingestion with 1 death), 5) 3 cases with alprenolol (1 death), 6) 4 cases with sotalol (2 cases of turned apex, 1 death), 7) 1 case with atenolol." | 3.66 | [Acute poisoning caused by beta blockers in the adult. Apropos of 7 cases]. ( Auzépy, P; Boukara, N; Giudicelli, JF; Richard, C, 1983) |
| " In animals pretreated with reserpine, propranolol, or aminophylline, pentylenetetrazol seizures were more severe, cyclic AMP elevations were attenuated or blocked, and cyclic GMP increases were unaffected or augmented." | 3.66 | Effects of reserpine, propranolol, and aminophylline on seizure activity and CNS cyclic nucleotides. ( Ferrendelli, JA; Gross, RA, 1979) |
| "The role of brain monoamines in the anticonvulsant effect of imipramine was investigated in albino rats, against maximal electroshock-induced seizures, by using drugs with well-defined effects on brain monoamines." | 3.65 | Role of brain monoamines in the anticonvulsant effect of imipramine in albino rats. ( Bhattacharya, SK; Das, PK; Mukhopadhyay, SN; Reddy, PK, 1976) |
| "l-Propranolol was found to protect mice from hyperbaric oxygen-induced seizures." | 3.65 | Disposition of propranolol isomers in mice. ( Finck, AD; Kawashima, K; Levy, A; Ngai, SH; Spector, S, 1976) |
| "Severe hypoglycemia was common in infants aged >1 year, when PPL was used for ≥6 months." | 1.72 | Severe hypoglycemia in propranolol treatment for infantile hemangiomas. ( Baba, N; Kaneko, T; Kuwano, Y; Morimoto, A; Ozeki, M; Sasaki, S, 2022) |
| "The additive anti-seizure effect of propranolol and lower doses of morphine was blocked by naltrexone in intraperitoneal PTZ model." | 1.43 | The interaction between morphine and propranolol in chemical and electrical seizure models of mice. ( Fakhrzad, A; Khosravani, E; Moezi, L; Shafaroodi, H, 2016) |
| " Combining of xanthone with piperazine moiety resulted in obtaining of compounds with increased bioavailability after oral administration." | 1.39 | Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety. ( Bojarski, AJ; Gunia, A; Marona, H; Pytka, K; Satała, G; Siwek, A; Szkaradek, N; Szneler, E; Waszkielewicz, AM, 2013) |
| "During seizures the occurrence of AV conduction blocks increased, predisposing Kv1." | 1.36 | Kv1.1 potassium channel deficiency reveals brain-driven cardiac dysfunction as a candidate mechanism for sudden unexplained death in epilepsy. ( Chen, TT; Glasscock, E; Klassen, TL; Noebels, JL; Yoo, JW, 2010) |
| "Propranolol is a beta-adrenoceptor antagonist used clinically." | 1.35 | Propranolol increases the threshold for lidocaine-induced convulsions in awake rats: a direct effect on the brain. ( Asada, A; Hase, I; Nakamura, T; Oda, Y; Takahashi, R; Tanaka, K, 2008) |
| "However, the attenuation of severe seizures by a single PRA, PHEN, DZP, or PHB cotreatment was accompanied by a decrease in the brain COCA concentration." | 1.31 | Comparison of effect of ethanol and anticonvulsants on cardiovascular drug-modified cocaine toxicity. ( Fukui, Y; Hayase, T; Yamamoto, K; Yamamoto, Y, 2000) |
| "Death, seizure, cardiovascular collapse, hypoglycemia, coma and respiratory depression." | 1.29 | Relative toxicity of beta blockers in overdose. ( Buckley, NA; Dawson, AH; Epid, D; Reith, DM; Sayer, GP; Whyte, IM, 1996) |
| "Pretreatment with reserpine had no effect on either the time to onset or duration of maximal dentate activation." | 1.28 | Cholinergic and adrenergic agents modify the initiation and termination of epileptic discharges in the dentate gyrus. ( Lothman, EW; Stringer, JL, 1991) |
| "Treatment with propranolol or isoproterenol did not have any effect on convulsive activity of PINX gerbils, except that isoproterenol increased the excitability of all the gerbils." | 1.28 | Noradrenergic involvement in pinealectomy induced convulsions in gerbils. ( Champney, TH, 1990) |
| "When haloperidol (1." | 1.28 | Protection against d-amphetamine toxicity. ( Albertson, TE; Derlet, RW; Rice, P, 1990) |
| "MK-801, at all doses, reduced seizures in all groups (p less than or equal to 0." | 1.28 | Antagonism of cocaine, amphetamine, and methamphetamine toxicity. ( Albertson, TE; Derlet, RW; Rice, P, 1990) |
| "Pretreatment with propranolol increased the time-to-seizure by 70% and practolol by 50% without altering gross lung appearance or lung wet wt/dry wt." | 1.27 | Beta adrenergic receptors and glucagon in seizures from exposure to oxygen at high pressure (OHP). ( Beckman, DL; Crittenden, DJ, 1983) |
| "kainic acid were a decrease in noradrenaline and an increase in 5-hydroxyindoleacetic acid in the acute (3 h after kainic acid injection) suggesting strongly increased neurotransmitter turnover in noradrenergic and serotonergic neurons." | 1.27 | Alpha 2-adrenoceptors modulate kainic acid-induced limbic seizures. ( Baran, H; Hornykiewicz, O; Hörtnagl, H; Sapetschnig, G; Sperk, G, 1985) |
| "Sixty seconds after the onset of seizure activity, the animals either received no drug (control) or propranolol (IV or IO via an 18-gauge spinal needle placed in the right proximal tibia)." | 1.27 | Suppression of pentylenetetrazol-elicited seizure activity by intraosseous propranolol in pigs. ( Dolce, K; Jim, KF; Kahn, C; Lathers, CM; Matthews, WD; Spivey, WH, 1988) |
| "Sotalol was used as a control drug to check which of the effects of propranolol could be regarded as due to beta blockade." | 1.26 | Propranolol and morphine. ( Navarro, G; Richardson, R; Zuban, AT, 1976) |
| "Epileptiform seizures resistant to treatment with diazepam and barbiturates were frequent and probably not solely caused by cerebral ischaemia." | 1.26 | Convulsions and possible spasm of the lower oesophageal sphincter in a fatal case of propranolol intoxication. ( Holm, HA; Kittang, E; Laake, K; Refstad, SO, 1981) |
| " Observed on four drug-induced behavior categories, it was found that both clonidine and propranolol attenuated the toxic effects of relatively low dose levels of digitoxin, while at higher digitoxin dose levels only propranolol was able to reduce significantly the ED50 and the LD50." | 1.26 | Effect of age, clonidine or propranolol on behavioral toxicity induced with digitoxin in mice. ( Felleman, VH; Palfai, T, 1982) |
| "Both patients experienced generalized seizures and had a transient intraventricular conduction defect on electrocardiogram." | 1.26 | Seizures and intraventricular conduction defect in propranolol poisoning. A report of two cases. ( Bock, J; Buiumsohn, A; Eisenberg, ES; Frishman, WH; Jacob, H; Rosen, N, 1979) |
| "The rise in seizure threshold still occurred when animals were pretreated with alpha-methyl-p-tyrosine (200 mg ." | 1.26 | Studies on the post-ictal rise in seizure threshold. ( Cowen, PJ; Green, AR; Nutt, DJ, 1981) |
| "d-Indenolol was less active than dl-indenolol in lowering of methamphetamine group toxicity and calming of fighting behavior, though muscle relaxant, hypolocomotive and anticonvulsant effects of d-indenolol were virtually equal to those of the racemate." | 1.26 | Effects of indenolol (YB-2), a new beta-adrenergic blocking agent, and its dextro isomer on the central nervous system of mice and rabbits. ( Maeno, H; Tachikawa, S; Takenaka, T, 1978) |
| "Glycogen was depleted only by amphetamine-like compounds or by bemegride-induced convulsions." | 1.25 | Physiological and drug-induced changes in the glycogen content of mouse brain. ( Hutchins, DA; Rogers, KJ, 1970) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 66 (72.53) | 18.7374 |
| 1990's | 12 (13.19) | 18.2507 |
| 2000's | 6 (6.59) | 29.6817 |
| 2010's | 5 (5.49) | 24.3611 |
| 2020's | 2 (2.20) | 2.80 |
| Authors | Studies |
|---|---|
| Marona, H | 2 |
| Szkaradek, N | 2 |
| Rapacz, A | 1 |
| Filipek, B | 1 |
| Dybała, M | 1 |
| Siwek, A | 2 |
| Cegła, M | 1 |
| Szneler, E | 2 |
| Waszkielewicz, AM | 1 |
| Gunia, A | 1 |
| Pytka, K | 1 |
| Satała, G | 1 |
| Bojarski, AJ | 1 |
| Tiefenbach, J | 1 |
| Park, JJ | 1 |
| Kaliaperumal, C | 1 |
| Morimoto, A | 1 |
| Ozeki, M | 1 |
| Sasaki, S | 1 |
| Baba, N | 1 |
| Kuwano, Y | 1 |
| Kaneko, T | 1 |
| Shafaroodi, H | 1 |
| Khosravani, E | 1 |
| Fakhrzad, A | 1 |
| Moezi, L | 1 |
| Glasscock, E | 1 |
| Yoo, JW | 1 |
| Chen, TT | 1 |
| Klassen, TL | 1 |
| Noebels, JL | 1 |
| Fusilli, G | 1 |
| Merico, G | 1 |
| Gurrado, R | 1 |
| Rosa, T | 1 |
| Acquafredda, A | 1 |
| Cavallo, L | 1 |
| Felippotti, TT | 1 |
| dos Reis Ferreira, CM | 1 |
| de Freitas, RL | 1 |
| de Oliveira, RC | 1 |
| de Oliveira, R | 1 |
| Paschoalin-Maurin, T | 1 |
| Coimbra, NC | 1 |
| Navarro, E | 1 |
| Alonso, SJ | 1 |
| Martín, FA | 1 |
| Castellano, MA | 1 |
| Nakamura, T | 1 |
| Oda, Y | 1 |
| Takahashi, R | 1 |
| Tanaka, K | 1 |
| Hase, I | 1 |
| Asada, A | 1 |
| Adams, CW | 1 |
| Nance, WE | 1 |
| Yue, W | 1 |
| Zhang, SS | 1 |
| Nutt, DJ | 1 |
| Cowen, PJ | 1 |
| Green, AR | 2 |
| Papanicolaou, J | 1 |
| Vajda, FJ | 1 |
| Summers, RJ | 1 |
| Louis, WJ | 1 |
| Auzépy, P | 1 |
| Boukara, N | 1 |
| Richard, C | 1 |
| Giudicelli, JF | 1 |
| Weinstein, RS | 1 |
| Peterson, SL | 1 |
| Albertson, TE | 4 |
| Stark, LG | 1 |
| Joy, RM | 1 |
| Gordon, LS | 1 |
| Folbergrová, J | 2 |
| Bowdler, JM | 1 |
| Crittenden, DJ | 1 |
| Beckman, DL | 1 |
| Wambebe, C | 1 |
| Osuide, G | 1 |
| Gamaniel, K | 1 |
| Pei, YQ | 1 |
| Yao, HY | 1 |
| Zhang, ZL | 1 |
| Mittleman, HS | 1 |
| Mittleman, RE | 1 |
| Elser, B | 1 |
| Tagashira, E | 1 |
| Hiramori, T | 1 |
| Nakao, K | 1 |
| Urano, T | 1 |
| Yanaura, S | 1 |
| Greenberg, A | 1 |
| Piraino, BH | 1 |
| Kroboth, PD | 1 |
| Weiss, J | 1 |
| Cunningham, JG | 1 |
| Stephenson, RB | 1 |
| Dolan, JG | 1 |
| Mushlin, AI | 1 |
| Smith, DL | 1 |
| Looney, TJ | 1 |
| Ashton, D | 1 |
| Leysen, JE | 1 |
| Wauquier, A | 1 |
| Parrish, C | 1 |
| Wooster, WE | 1 |
| Braen, GR | 1 |
| Robertson, HD | 1 |
| Palfai, T | 1 |
| Felleman, VH | 1 |
| Canedo, MI | 1 |
| Frank, MJ | 1 |
| Abdulla, AM | 1 |
| Waddingham, S | 1 |
| Belknap, JK | 1 |
| Canada, AT | 1 |
| Lesko, LJ | 1 |
| Halloran, TJ | 1 |
| Phillips, CE | 1 |
| Billimoria, RB | 1 |
| Naik, PR | 1 |
| Satoskar, RS | 1 |
| Laake, K | 1 |
| Kittang, E | 1 |
| Refstad, SO | 1 |
| Holm, HA | 1 |
| Guinn, MM | 1 |
| Bedford, JA | 1 |
| Wilson, MC | 1 |
| Amabeoku, G | 1 |
| Chandomba, R | 1 |
| Ferraro, G | 1 |
| Sardo, P | 1 |
| Sabatino, M | 1 |
| Caravaglios, G | 1 |
| La Grutta, V | 1 |
| Tseng, CC | 1 |
| Derlet, RW | 3 |
| Reith, DM | 1 |
| Dawson, AH | 1 |
| Epid, D | 1 |
| Whyte, IM | 1 |
| Buckley, NA | 1 |
| Sayer, GP | 1 |
| Amabeoku, GJ | 1 |
| Syce, JA | 1 |
| Raju, SS | 1 |
| Gopalakrishna, HN | 1 |
| Venkatadri, N | 1 |
| Hayase, T | 1 |
| Yamamoto, Y | 1 |
| Yamamoto, K | 1 |
| Fukui, Y | 1 |
| Pericic, D | 1 |
| Jazvinscak, M | 1 |
| Svob, D | 1 |
| Mirkovic, K | 1 |
| Fischer, W | 1 |
| Tachikawa, S | 1 |
| Takenaka, T | 1 |
| Maeno, H | 1 |
| Anlezark, G | 1 |
| Horton, R | 1 |
| Meldrum, B | 1 |
| Huh, S | 1 |
| Kim, KH | 1 |
| Hong, SS | 1 |
| Frishman, W | 1 |
| Jacob, H | 2 |
| Eisenberg, E | 1 |
| Ribner, H | 1 |
| Navarro, G | 1 |
| Richardson, R | 1 |
| Zuban, AT | 1 |
| Sabelli, HC | 1 |
| Diamond, BI | 1 |
| May, J | 1 |
| Havdala, HS | 1 |
| Bhattacharya, SK | 1 |
| Mukhopadhyay, SN | 1 |
| Reddy, PK | 1 |
| Das, PK | 1 |
| Gross, RA | 1 |
| Ferrendelli, JA | 1 |
| Callaghan, DA | 1 |
| Schwark, WS | 1 |
| Buiumsohn, A | 1 |
| Eisenberg, ES | 1 |
| Rosen, N | 1 |
| Bock, J | 1 |
| Frishman, WH | 1 |
| Dadkar, VN | 1 |
| Dahanukar, SA | 1 |
| Sheth, UK | 1 |
| Robertson, CC | 1 |
| Sellers, EM | 1 |
| Tartara, A | 1 |
| Bo, P | 1 |
| Savoldi, F | 1 |
| Bolzani, L | 1 |
| Levy, A | 1 |
| Ngai, SH | 1 |
| Finck, AD | 1 |
| Kawashima, K | 1 |
| Spector, S | 1 |
| Kittner, H | 1 |
| Müller, M | 2 |
| Stringer, JL | 1 |
| Lothman, EW | 1 |
| Rice, P | 2 |
| Champney, TH | 1 |
| Lohmann, D | 1 |
| Lehmann, D | 1 |
| Morgenstern, E | 1 |
| Faust, G | 1 |
| Akkan, AG | 1 |
| Yillar, DO | 1 |
| Eşkazan, E | 1 |
| Akcasu, A | 1 |
| Ozüner, Z | 1 |
| Schramek, J | 1 |
| Mares, P | 1 |
| Picková, M | 1 |
| Wamil, A | 1 |
| Kleinrok, Z | 1 |
| Gothóni, P | 1 |
| Ikola, W | 1 |
| Oehler, J | 1 |
| Jähkel, M | 1 |
| Schmidt, J | 1 |
| Schneider, SM | 1 |
| Borok, Z | 1 |
| Michelson, EA | 1 |
| Lints, CE | 1 |
| Nyquist-Battie, C | 1 |
| Baran, H | 1 |
| Sperk, G | 1 |
| Hörtnagl, H | 1 |
| Sapetschnig, G | 1 |
| Hornykiewicz, O | 1 |
| Jim, KF | 1 |
| Lathers, CM | 1 |
| Spivey, WH | 1 |
| Matthews, WD | 1 |
| Kahn, C | 1 |
| Dolce, K | 1 |
| Lane, AS | 1 |
| Woodward, AC | 1 |
| Goldman, MR | 1 |
| Russell, RD | 1 |
| Stripling, JS | 1 |
| Brichard, G | 1 |
| Murmann, W | 1 |
| Almirante, L | 1 |
| Saccani-Guelfi, M | 1 |
| Yeoh, PN | 1 |
| Wolf, HH | 1 |
| McBride, JT | 1 |
| McBride, MC | 1 |
| Viles, PH | 1 |
| Saelens, DA | 2 |
| Walle, T | 2 |
| Privitera, PJ | 2 |
| Knapp, DR | 2 |
| Gaffney, T | 2 |
| Trivedi, CP | 1 |
| Sharma, RD | 1 |
| Bauditz, W | 2 |
| Bartelheimer, HK | 2 |
| Hutchins, DA | 1 |
| Rogers, KJ | 1 |
| Koppanyi, T | 1 |
| Maling, HM | 1 |
| Saul, W | 1 |
| Brodie, BB | 1 |
2 reviews available for propranolol and Seizures
| Article | Year |
|---|---|
A 5-year outcome of propranolol for the treatment of paediatric intracranial cavernoma: case report and a review of the literature.
Topics: Child; Hemangioma, Cavernous, Central Nervous System; Humans; Intracranial Hemorrhages; Magnetic Res | 2023 |
Recognition and management of poisoning with beta-adrenergic blocking agents.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Coma; Cyanosis; Epinephrine; G | 1984 |
1 trial available for propranolol and Seizures
| Article | Year |
|---|---|
[Practolol in anesthesia (ICI 50.172, Eraldin)].
Topics: Acetanilides; Adolescent; Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Amino Alcohols; Ane | 1972 |
88 other studies available for propranolol and Seizures
| Article | Year |
|---|---|
Preliminary evaluation of pharmacological properties of some xanthone derivatives.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Anti-Arrh | 2009 |
Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety.
Topics: Administration, Oral; Animals; Anticonvulsants; Drug Evaluation, Preclinical; Electroshock; Half-Lif | 2013 |
Severe hypoglycemia in propranolol treatment for infantile hemangiomas.
Topics: Adrenergic beta-Antagonists; Child; Female; Hemangioma; Hemangioma, Capillary; Humans; Hypoglycemia; | 2022 |
The interaction between morphine and propranolol in chemical and electrical seizure models of mice.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administrat | 2016 |
Kv1.1 potassium channel deficiency reveals brain-driven cardiac dysfunction as a candidate mechanism for sudden unexplained death in epilepsy.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrioventricular Block; Atropine; Bradycardia | 2010 |
Propranolol for infantile haemangiomas and neuroglycopenic seizures.
Topics: Adrenergic beta-Antagonists; Blood Glucose; Hemangioma; Humans; Hyperphagia; Hypoglycemia; Infant; L | 2010 |
Paradoxical effect of noradrenaline-mediated neurotransmission in the antinociceptive phenomenon that accompanies tonic-clonic seizures: role of locus coeruleus neurons and α(2)- and β-noradrenergic receptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Neurons; Animals; Disease Models, Animal; Dose-R | 2011 |
Toxicological and pharmacological effects of D-arginine.
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Autonomic Nervous System; Behavior, Animal; Betameth | 2005 |
Propranolol increases the threshold for lidocaine-induced convulsions in awake rats: a direct effect on the brain.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Anticonvulsants; Brain; Dose-Response Rela | 2008 |
Persistent tachycardia, paroxymal hypertension, and seizures: association with hyperglycinuria, dominantly inherited microphthalmia, and cataracts.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Cataract; Female; Glycine; Humans; Hyperte | 1967 |
[Effects of clonidine and yohimbine on semicarbazide-induced convulsion and electroconvulsive shock].
Topics: Animals; Clonidine; Electroshock; Female; Hydroxydopamines; Male; Mice; Oxidopamine; Propranolol; Re | 1984 |
Studies on the post-ictal rise in seizure threshold.
Topics: Animals; Anticonvulsants; Bicuculline; Brain; Convulsants; Electroshock; GABA Antagonists; Halothane | 1981 |
Role of beta-adrenoceptors in the anticonvulsant effect of propranolol on leptazol-induced convulsions in rats.
Topics: Animals; Anticonvulsants; Female; Male; Pentylenetetrazole; Propranolol; Rats; Rats, Inbred Strains; | 1982 |
[Acute poisoning caused by beta blockers in the adult. Apropos of 7 cases].
Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Adult; Alcohol Drinking; Bradycardia; Coma; Dos | 1983 |
Cumulative after-discharge as the principal factor in the acquisition of kindled seizures.
Topics: Animals; Brain; Diazepam; Male; Phenobarbital; Propranolol; Rats; Seizures | 1981 |
Homocysteine-induced seizures in the mouse cerebral cortex after propranolol pretreatment. Lack of correlation between cyclic adenosine monophosphate levels and phosphorylase activation.
Topics: Animals; Cerebral Cortex; Cyclic AMP; Homocysteine; Male; Mice; Mice, Inbred Strains; Phosphorylases | 1981 |
Regional rat brain benzodiazepine receptor number and gamma-aminobutyric acid concentration following a convulsion.
Topics: Anesthesia; Animals; Bicuculline; Brain; Electroshock; gamma-Aminobutyric Acid; Male; Nerve Tissue P | 1982 |
Beta adrenergic receptors and glucagon in seizures from exposure to oxygen at high pressure (OHP).
Topics: Animals; Glucagon; Hyperbaric Oxygenation; Isoproterenol; Lung; Male; Practolol; Propranolol; Rats; | 1983 |
Influence of levodopa, apomorphine and 3,4-dihydroxyphenylserine (DOPS) on strychnine-induced seizures in mice.
Topics: Animals; Apomorphine; Droxidopa; Levodopa; Mice; Phentolamine; Propranolol; Seizures; Serine; Strych | 1984 |
[Central depressive action of propranolol (author's transl)].
Topics: Animals; Central Nervous System Depressants; Female; Male; Mice; Phenobarbital; Phenytoin; Propranol | 1981 |
Cocaine.
Topics: Cocaine; Emergencies; Fever; Humans; Hypertension; Propranolol; Seizures; Substance-Related Disorder | 1984 |
Effects of central monoamine compounds on tranylcypromine-induced barbital-withdrawal convulsions.
Topics: alpha-Methyltyrosine; Animals; Barbital; Barbiturates; Dose-Response Relationship, Drug; Humans; Mal | 1983 |
Severe theophylline toxicity. Role of conservative measures, antiarrhythmic agents, and charcoal hemoperfusion.
Topics: Aged; Heart Rate; Hemoperfusion; Humans; Hypotension; Kinetics; Male; Middle Aged; Propranolol; Seiz | 1984 |
Influence of phentolamine and propranolol on the length of tonus and clonus in pentylenetetrazol-induced seizures in dogs.
Topics: Animals; Dog Diseases; Dogs; Female; Humans; Male; Muscle Contraction; Muscle Tonus; Pentylenetetraz | 1984 |
Hypertension, vascular headaches, and seizures after carotid endarterectomy. Case report and therapeutic considerations.
Topics: Carotid Arteries; Endarterectomy; Female; Humans; Hypertension; Middle Aged; Phenobarbital; Prazosin | 1984 |
Seizures secondary to thyrotoxicosis and high-dosage propranolol therapy.
Topics: Adolescent; Humans; Hyperthyroidism; Male; Propranolol; Seizures | 1983 |
Neurotransmitters and receptor binding in amygdaloid kindled rats: serotonergic and noradrenergic modulatory effects.
Topics: 5-Hydroxytryptophan; Amygdala; Animals; Brain; Clonidine; Dexetimide; Electric Stimulation; Male; Mi | 1980 |
Les torsades des pointes.
Topics: Adolescent; Diagnosis, Differential; Electrocardiography; Female; Heart Ventricles; Humans; Pacemake | 1982 |
Effect of age, clonidine or propranolol on behavioral toxicity induced with digitoxin in mice.
Topics: Aging; Animals; Behavior, Animal; Clonidine; Digitoxin; Drug Interactions; Gait; Male; Mice; Postura | 1982 |
Rhythm disturbances in hypertrophic cardiomyopathy: prevalence, relation to symptoms and management.
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Elect | 1980 |
Barbiturate dependence in mice: effects of propranolol on the withdrawal syndrome.
Topics: Animals; Barbiturates; Disease Models, Animal; Humans; Isomerism; Male; Mice; Mice, Inbred C57BL; Pr | 1980 |
Two reasons for unusual therapeutic drug monitoring results in hospitalized patients.
Topics: Adult; Aged; Drug Therapy; Female; Hospitalization; Humans; Hypertension, Malignant; Male; Medicatio | 1980 |
Propranolol intoxication. A severe case responding to norepinephrine therapy.
Topics: Coma; Female; Half-Life; Humans; Hypotension; Isoproterenol; Middle Aged; Norepinephrine; Propranolo | 1981 |
Effect of diazepam alone and in combination with chlorpromazine or propranolol in experimentally induced convulsions in mice.
Topics: Animals; Chlorpromazine; Diazepam; Drug Therapy, Combination; Electroshock; Male; Mice; Pentylenetet | 1981 |
Convulsions and possible spasm of the lower oesophageal sphincter in a fatal case of propranolol intoxication.
Topics: Adult; Esophageal Stenosis; Esophagogastric Junction; Female; Humans; Propranolol; Seizures; Suicide | 1981 |
Antagonism of intravenous cocaine lethality in nonhuman primates.
Topics: Animals; Behavior, Animal; Chlorpromazine; Cocaine; Diazepam; Hemodynamics; Infusions, Parenteral; M | 1980 |
Strychnine-induced seizures in mice: the role of noradrenaline.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Disulfiram; Droxidopa; Idazoxan; Imipram | 1994 |
Anticonvulsant activity of the noradrenergic locus coeruleus system: role of beta mediation.
Topics: Animals; Hippocampus; Injections; Injections, Intraperitoneal; Locus Coeruleus; Male; Norepinephrine | 1994 |
Acute cocaine toxicity: the effect of agents in non-seizure-induced death.
Topics: Animals; Anticonvulsants; Cocaine; Diazepam; Electrodes, Implanted; Electroencephalography; Male; Ni | 1993 |
Relative toxicity of beta blockers in overdose.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Child, Preschool; Databases, Factual | 1996 |
Propranolol-induced seizures in mice: the role of noradrenaline.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic Uptake Inhibitors; alpha-Methyltyros | 1997 |
Effect of propranolol and nifedipine on maximal electroshock-induced seizures in mice: individually and in combination.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Nifedipine; Ph | 1998 |
Comparison of effect of ethanol and anticonvulsants on cardiovascular drug-modified cocaine toxicity.
Topics: Animals; Anticonvulsants; Cardiovascular Agents; Cocaine; Diazepam; Enalapril; Ethanol; Male; Mice; | 2000 |
Beta-1 adrenoceptor antagonists potentiate the anticonvulsive effect of swim stress in mice.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Betaxolol; Convulsants; Male; Mice; Mice, Inbred CB | 2000 |
Anticonvulsant profile and mechanism of action of propranolol and its two enantiomers.
Topics: Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Cells, Cultured; Dose-Response Relati | 2002 |
Effects of indenolol (YB-2), a new beta-adrenergic blocking agent, and its dextro isomer on the central nervous system of mice and rabbits.
Topics: Adrenergic beta-Antagonists; Aggression; Animals; Behavior, Animal; Blood Pressure; Central Nervous | 1978 |
The anticonvulsant action of the (-)- and (+)-enantiomers of propranolol.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Mice; Propranolol; Seizures; Stereoisomerism | 1979 |
Effect of beta-adrenergic blockers on experimentally-induced convulsion and narcosis.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Anticonvulsants; Blood Pressure; Chickens; Heart R | 1978 |
Clinical pharmacology of the new beta-adrenergic blocking drugs. Part 8. Self-poisoning with beta-adrenoceptor blocking agents: recognition and management.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Bronchial Spasm; Female; Humans; Hypoglycemia; Male; | 1979 |
Propranolol and morphine.
Topics: Animals; Lethal Dose 50; Male; Mice; Morphine; Propranolol; Receptors, Adrenergic, beta; Seizures; S | 1976 |
Differential interactions of phenobarbital and pentobarbital with beta-adrenergic mechanisms in vitro and in vivo.
Topics: Action Potentials; Animals; Anura; Bucladesine; Calcium; Cyclic AMP; Dose-Response Relationship, Dru | 1977 |
Role of brain monoamines in the anticonvulsant effect of imipramine in albino rats.
Topics: Animals; Anticonvulsants; Apomorphine; Catecholamines; Ditiocarb; Dopamine; Drug Interactions; Elect | 1976 |
Changes of cyclic AMP and phosphorylase a in mouse cerebral cortex during seizures induced by 3-mercaptopropionic acid.
Topics: 3-Mercaptopropionic Acid; Animals; Cerebral Cortex; Cyclic AMP; Male; Mice; Phenobarbital; Phosphory | 1977 |
Effects of reserpine, propranolol, and aminophylline on seizure activity and CNS cyclic nucleotides.
Topics: Aminophylline; Animals; Brain; Cyclic AMP; Cyclic GMP; Female; Mice; Pentylenetetrazole; Propranolol | 1979 |
Involvement of catecholamines in kindled amygdaloid convulsions in the rat.
Topics: Amygdala; Animals; Catecholamines; Disulfiram; Dopamine; Electric Stimulation; Male; Norepinephrine; | 1979 |
Seizures and intraventricular conduction defect in propranolol poisoning. A report of two cases.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Bradycardia; Female; Humans; Propranolol; Seizures; Substan | 1979 |
Role of dopaminergic and noradrenergic mechanisms in Metrazole convulsions in mice.
Topics: Animals; Apomorphine; Benserazide; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Clonidine; | 1979 |
Alcohol intoxication and the alcohol withdrawal syndrome.
Topics: Alcoholic Intoxication; Alcoholism; Benzodiazepines; Chlordiazepoxide; Hallucinations; Humans; Pheny | 1978 |
Experimental research on antiepileptic activity of propranolol.
Topics: Animals; Propranolol; Rabbits; Seizures | 1977 |
Disposition of propranolol isomers in mice.
Topics: Animals; Drug Synergism; Hyperbaric Oxygenation; Male; Mice; Propranolol; Radioimmunoassay; Seizures | 1976 |
[The effect of propranolol on seizure development in pentylenetetrazole-kindling in the rat].
Topics: Animals; Male; Pentylenetetrazole; Propranolol; Rats; Rats, Inbred Strains; Seizures | 1991 |
Cholinergic and adrenergic agents modify the initiation and termination of epileptic discharges in the dentate gyrus.
Topics: Animals; Atropine; Clonidine; Electric Stimulation; Epilepsy; Hippocampus; Male; Parasympathomimetic | 1991 |
Antagonism of cocaine, amphetamine, and methamphetamine toxicity.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Diazepam; Dimethyl Sulfoxide; Dizocilpine Maleate; | 1990 |
Noradrenergic involvement in pinealectomy induced convulsions in gerbils.
Topics: alpha-Methyltyrosine; Animals; Gerbillinae; Hypothalamus; Isoproterenol; Male; Methyltyrosines; Nore | 1990 |
Protection against d-amphetamine toxicity.
Topics: Animals; Dextroamphetamine; Diazepam; Dose-Response Relationship, Drug; Haloperidol; Injections, Int | 1990 |
[Synthesis and anticonvulsant action of propranolol derivatives with a tertiary nitrogen atom].
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Electroshock; Male; Mice; Pentylenetetrazol | 1990 |
The effect of propranolol on maximal electroshock seizures in mice.
Topics: Animals; Electroshock; Female; Male; Mice; Propranolol; Seizures | 1989 |
Combined application of propranolol and local anesthetics: enhanced anticonvulsant action.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Lidocaine; | 1989 |
Influence of propranolol on metrazol-induced seizures during ontogenesis in rats.
Topics: Animals; Male; Pentylenetetrazole; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, b | 1987 |
Role of noradrenergic system in limbic seizures induced by pilocarpine. I. Importance of beta-adrenergic receptor.
Topics: Albuterol; Animals; Disease Models, Animal; Lidocaine; Limbic System; Male; Pilocarpine; Propranolol | 1988 |
Ethanol withdrawal tremor potentiates the tremorogenic action of nicotine.
Topics: Animals; Ethanol; Hexamethonium; Hexamethonium Compounds; Male; Nicotine; Propranolol; Rats; Rats, I | 1985 |
Altered neurobiological responses to acute immobilization in social-isolated mice.
Topics: Animals; Apomorphine; Brain; Lysergic Acid Diethylamide; Male; Mice; Neurotransmitter Agents; Pentyl | 1986 |
Beta-blockade for acute theophylline-induced seizures.
Topics: Adrenergic beta-Antagonists; Animals; Blood Glucose; Male; Potassium; Propranolol; Rats; Rats, Inbre | 1987 |
A possible role for beta-adrenergic receptors in the expression of audiogenic seizures.
Topics: Acoustic Stimulation; Animals; Brain Chemistry; Female; Male; Mice; Mice, Inbred C57BL; Mice, Inbred | 1985 |
Alpha 2-adrenoceptors modulate kainic acid-induced limbic seizures.
Topics: Animals; Brain Chemistry; Clonidine; Diazepam; Haloperidol; Kainic Acid; Male; Metergoline; Prazosin | 1985 |
Suppression of pentylenetetrazol-elicited seizure activity by intraosseous propranolol in pigs.
Topics: Animals; Blood Pressure; Bone and Bones; Dose-Response Relationship, Drug; Electroencephalography; H | 1988 |
Massive propranolol overdose poorly responsive to pharmacologic therapy: use of the intra-aortic balloon pump.
Topics: Adolescent; Electric Countershock; Female; Humans; Intra-Aortic Balloon Pumping; Propranolol; Resusc | 1987 |
Monoaminergic and local anesthetic components of cocaine's effects on kindled seizure expression.
Topics: Amphetamine; Anesthetics, Local; Animals; Biogenic Amines; Cocaine; Drug Interactions; Haloperidol; | 1985 |
Effects of hexobarbitone, ether, morphine, and urethane upon the acute toxicity of propranolol and D-(--)-INPEA.
Topics: Amino Alcohols; Animals; Atropine; Bradycardia; Central Nervous System; Drug Synergism; Ethers; Hear | 1966 |
Pharmacological evaluation of seizures induced by electrical stimulation of the hippocampus.
Topics: Amino Alcohols; Anilides; Animals; Electric Stimulation; Ethanolamines; Hippocampus; Male; Methods; | 1970 |
Hypoglycemia associated with propranolol.
Topics: Blood Glucose; Child, Preschool; Fasting; Glucose; Humans; Hypoglycemia; Male; Propranolol; Seizures | 1973 |
The psychopharmacological effects of a new metabolite of propranolol.
Topics: Animals; Behavior, Animal; Chromatography, Gas; Glycols; Mass Spectrometry; Mephenesin; Mice; Propra | 1973 |
Neuro pharmacological studies on propranolol--a beta adrenergic blocking agent.
Topics: Analgesics; Animals; Columbidae; Motor Activity; Pentobarbital; Propranolol; Rats; Seizures; Sleep; | 1973 |
Central nervous system effects and metabolic disposition of a glycol metabolite of propranolol.
Topics: Animals; Anticonvulsants; Behavior, Animal; Biotransformation; Central Nervous System; Dose-Response | 1974 |
[Hemodialysis treatment of a 3 1-4-year-old child with imipramine poisoning].
Topics: Arrhythmias, Cardiac; Charcoal; Child, Preschool; Chloral Hydrate; Electrocardiography; Electroencep | 1970 |
Physiological and drug-induced changes in the glycogen content of mouse brain.
Topics: Amphetamine; Animals; Bemegride; Body Temperature; Brain Chemistry; Caffeine; Catecholamines; Circad | 1970 |
Jumping activity induced by sodium 5-(1,3-dim- ethylbutyl)-5-ethyl barbiturate. II. The effects of age difference.
Topics: Age Factors; Animals; Barbiturates; Chlorisondamine; Male; Mice; Motor Activity; Propranolol; Seizur | 1970 |
[Treatment of imipramine poisoning at childhood].
Topics: Arrhythmias, Cardiac; Carbon; Child, Preschool; Chloral Hydrate; Coma; Gastric Lavage; Humans; Hypot | 1970 |