proadifen has been researched along with Seizures in 11 studies
Proadifen: An inhibitor of drug metabolism and CYTOCHROME P-450 ENZYME SYSTEM activity.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Some of the more striking expressions of toxicity are the tremors and seizures observed approximately 100 min after exposure of rats to an acutely toxic dose of acrylonitrile (AN)." | 3.73 | Effect of cytochrome P450 inhibitors and anticonvulsants on the acute toxicity of acrylonitrile. ( Benz, FW; Nerland, DE, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| VEATCH, RM | 1 |
| ADLER, TK | 1 |
| WAY, EL | 1 |
| Benz, FW | 1 |
| Nerland, DE | 1 |
| Ater, SB | 1 |
| Swinyard, EA | 1 |
| Tolman, KG | 1 |
| Madsen, JA | 1 |
| Matsuo, F | 1 |
| Bourgeois, BF | 1 |
| Wad, N | 1 |
| Turnbull, MJ | 1 |
| Watkins, JW | 1 |
| Baumel, I | 1 |
| Carlson, GP | 1 |
| Lal, H | 1 |
| Goldberg, ME | 1 |
| Sledge, K | 1 |
| Dubinsky, B | 1 |
| Robichaud, RC | 1 |
| Hunt, WA | 1 |
| Dar, MS | 1 |
| Fakouhi, T | 1 |
| Davis, WM | 1 |
| Yeh, JZ | 1 |
| Solymoss, B | 1 |
| Toth, S | 1 |
| Varga, S | 1 |
| Selye, H | 1 |
11 other studies available for proadifen and Seizures
| Article | Year |
|---|---|
THE IMPORTANCE OF STERIC CONFIGUA. ION IN CERTAIN MORPHINNE-MIMETIC ACTIONS OF SYNTHETIC ANALGETICS.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Apnea; Chemical Phenomena; Chemistry; Methadone; | 1964 |
Effect of cytochrome P450 inhibitors and anticonvulsants on the acute toxicity of acrylonitrile.
Topics: Acrylonitrile; Animals; Anticonvulsants; Carcinogens; Central Nervous System Depressants; Cyanides; | 2005 |
Effects of SKF525A, phenobarbital, fasting, and carnitine on the anticonvulsant activity and neurotoxicity of valproate in mice.
Topics: Animals; Carnitine; Fasting; Male; Mice; Mice, Inbred Strains; Nervous System; Phenobarbital; Proadi | 1984 |
Individual and combined antiepileptic and neurotoxic activity of carbamazepine and carbamazepine-10,11-epoxide in mice.
Topics: Animals; Brain; Carbamazepine; Drug Synergism; Female; Mice; Mice, Inbred ICR; Nervous System; Proad | 1984 |
Determination of halothane-induced sleeping time in the rat: effect of prior administration of centrally active drugs.
Topics: Animals; Bemegride; Brain Chemistry; Circadian Rhythm; Drug Interactions; Female; Halothane; Injecti | 1976 |
Role of hepatic metabolism in the convulsant action of m-fluorotyrosine.
Topics: Animals; Brain; Central Nervous System Stimulants; Fluorine; Hepatectomy; Injections; Injections, In | 1971 |
The influence of SKF-525A on the acute pharmacological properties of chlordiazepoxide.
Topics: Aggression; Animals; Avoidance Learning; Behavior, Animal; Brain; Chlordiazepoxide; Conflict, Psycho | 1973 |
Changes in the neuro-excitability of alcohol-dependent rats undergoing withdrawal as measured by the pentylenetetrazole seizure threshold.
Topics: Animals; Disease Susceptibility; Ethanol; Humans; Male; Pentylenetetrazole; Proadifen; Rats; Seizure | 1973 |
Studies on some aspects of the neuropharmacology of butylurea.
Topics: Administration, Oral; Analgesics; Animals; Anticonvulsants; Barbiturates; Butanes; Central Nervous S | 1974 |
Susceptibility to strychnine convulsions in maturing rats.
Topics: Age Factors; Animals; Liver; Proadifen; Rats; Seizures; Strychnine | 1969 |
Protection by spironolactone and oxandrolone against chronic digitoxin or indomethacin intoxication.
Topics: Animals; Digitoxin; Drug Antagonism; Female; Indomethacin; Intestinal Diseases; Jejunum; Microsomes, | 1971 |