fenofibrate has been researched along with Seizures in 2 studies
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Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Consistently, nicotine elicits seizures through nAChRs and mimics the excessive nAChR activation observed in animal models of the disease." | 3.79 | PPAR-alpha agonists as novel antiepileptic drugs: preclinical findings. ( Aroni, S; Carta, G; De Montis, MG; Lecca, S; Marrosu, F; Melis, M; Muntoni, AL; Murru, E; Pillolla, G; Pistis, M; Puligheddu, M; Scheggi, S, 2013) |
| "Epileptic seizures are the most common neurological diseases that change the function of neurovascular unit at molecular levels accompanied by activation of a wide variety of neurodegenerative cascades." | 1.62 | Fenofibrate protects the neurovascular unit and ameliorates plasma corticosterone levels in pentylenetetrazole-induced kindling seizure in mice. ( Darabi, S; Faghihi, N; Mohammadi, MT; Sarahian, N, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sarahian, N | 1 |
| Mohammadi, MT | 1 |
| Darabi, S | 1 |
| Faghihi, N | 1 |
| Puligheddu, M | 1 |
| Pillolla, G | 1 |
| Melis, M | 1 |
| Lecca, S | 1 |
| Marrosu, F | 1 |
| De Montis, MG | 1 |
| Scheggi, S | 1 |
| Carta, G | 1 |
| Murru, E | 1 |
| Aroni, S | 1 |
| Muntoni, AL | 1 |
| Pistis, M | 1 |
2 other studies available for fenofibrate and Seizures
| Article | Year |
|---|---|
Fenofibrate protects the neurovascular unit and ameliorates plasma corticosterone levels in pentylenetetrazole-induced kindling seizure in mice.
Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Brain; Brain-Derived Neurotrophic Factor; Convulsants | 2021 |
PPAR-alpha agonists as novel antiepileptic drugs: preclinical findings.
Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Epilepsy, Frontal Lobe; Fenofibrate; Frontal | 2013 |