Page last updated: 2024-10-27

fenofibrate and Seizures

fenofibrate has been researched along with Seizures in 2 studies

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Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
" Consistently, nicotine elicits seizures through nAChRs and mimics the excessive nAChR activation observed in animal models of the disease."3.79PPAR-alpha agonists as novel antiepileptic drugs: preclinical findings. ( Aroni, S; Carta, G; De Montis, MG; Lecca, S; Marrosu, F; Melis, M; Muntoni, AL; Murru, E; Pillolla, G; Pistis, M; Puligheddu, M; Scheggi, S, 2013)
"Epileptic seizures are the most common neurological diseases that change the function of neurovascular unit at molecular levels accompanied by activation of a wide variety of neurodegenerative cascades."1.62Fenofibrate protects the neurovascular unit and ameliorates plasma corticosterone levels in pentylenetetrazole-induced kindling seizure in mice. ( Darabi, S; Faghihi, N; Mohammadi, MT; Sarahian, N, 2021)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Sarahian, N1
Mohammadi, MT1
Darabi, S1
Faghihi, N1
Puligheddu, M1
Pillolla, G1
Melis, M1
Lecca, S1
Marrosu, F1
De Montis, MG1
Scheggi, S1
Carta, G1
Murru, E1
Aroni, S1
Muntoni, AL1
Pistis, M1

Other Studies

2 other studies available for fenofibrate and Seizures

ArticleYear
Fenofibrate protects the neurovascular unit and ameliorates plasma corticosterone levels in pentylenetetrazole-induced kindling seizure in mice.
    Brain research, 2021, 05-01, Volume: 1758

    Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Brain; Brain-Derived Neurotrophic Factor; Convulsants

2021
PPAR-alpha agonists as novel antiepileptic drugs: preclinical findings.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Epilepsy, Frontal Lobe; Fenofibrate; Frontal

2013