trimethyltin hydroxide: neurotoxic cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 6328620 |
| MeSH ID | M0113928 |
| Synonym |
|---|
| hydroxytrimethylstannane |
| hydroxytrimethyltin |
| tin, hydroxytrimethyl- |
| tin, trimethyl-, hydroxide |
| stannane, hydroxytrimethyl- |
| trimethylhydroxytin |
| trimethyltin hydroxide |
| trimethylstannyl hydroxide |
| ai3-52035 |
| trimethylstannanol |
| 56-24-6 |
| 10alt8dj2v , |
| unii-10alt8dj2v |
| DTXSID9032240 |
| AKOS025395384 |
| mfcd00013929 |
| AS-57825 |
| AT34590 |
| Excerpt | Relevance | Reference |
|---|---|---|
| " ASR thresholds for 40-kHz tones were elevated 25-35 dB in all dosage groups." | ( Trimethyltin effects on auditory function and cochlear morphology. Crofton, KM; Dean, KF; Janssen, R; Ménache, MG, 1990) | 0.28 |
| " To determine if TMT altered monoamine turnover or metabolite efflux, mice were dosed with 0 or 3 mg/kg TMT; 2 weeks later, pargyline (75 mg/kg, intraperitoneally) was administered and the mice sacrificed 0, 30 and 60 min." | ( Cholinergic and dopaminergic alterations in the mouse central nervous system following acute trimethyltin exposure. Ali, SF; Goad, PT; Newport, GD; Slikker, W, 1986) | 0.27 |
| " Long Evans hooded rats were intragastrically dosed with 4 mg TMT hydroxide/kg body weight for 4 days." | ( The use of Synapsin I as a biochemical marker for neuronal damage by trimethyltin. Goodrum, JF; Harry, GJ; Krigman, MR; Morell, P, 1985) | 0.27 |
| " The size of the milk bands was decreased in 6 mg/kg TMT pups 48-96 hr after dosing, while in 5 mg/kg TMT pups, milk bands were reduced 96 hr after dosing only." | ( Developmental and behavioral toxicity following acute postnatal exposure of rat pups to trimethyltin. Dean, KF; Reiter, LW; Ruppert, PH, ) | 0.13 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 8 (42.11) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (35.90) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (4.76%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 20 (95.24%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||