1-(3-trifluoromethylphenyl)piperazine has been researched along with Seizures in 2 studies
1-(3-trifluoromethylphenyl)piperazine: acts as serotonin agonist; structure
1-(3-(trifluoromethyl)phenyl)piperazine : A N-arylpiperazine that is piperazine substituted by a 3-(trifluoromethyl)phenyl group at position 1. A serotonergic agonist used as a recreational drug.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluoxetine, a serotonin (5-HT) reuptake inhibitor, has been documented to exert a protective action against convulsive seizures in animal models, when administered either systemically, or focally into substantia nigra." | 3.69 | The anticonvulsant action of fluoxetine in substantia nigra is dependent upon endogenous serotonin. ( Gale, K; Pasini, A; Tortorella, A, 1996) |
| "Seizures are induced in some patients even at low doses." | 2.47 | The clinical toxicology of the designer "party pills" benzylpiperazine and trifluoromethylphenylpiperazine. ( Beasley, DM; Gee, P; Schep, LJ; Slaughter, RJ; Vale, JA, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schep, LJ | 1 |
| Slaughter, RJ | 1 |
| Vale, JA | 1 |
| Beasley, DM | 1 |
| Gee, P | 1 |
| Pasini, A | 1 |
| Tortorella, A | 1 |
| Gale, K | 1 |
1 review available for 1-(3-trifluoromethylphenyl)piperazine and Seizures
| Article | Year |
|---|---|
The clinical toxicology of the designer "party pills" benzylpiperazine and trifluoromethylphenylpiperazine.
Topics: Designer Drugs; Fever; Humans; Illicit Drugs; Piperazines; Seizures; Serotonin Receptor Agonists; Su | 2011 |
1 other study available for 1-(3-trifluoromethylphenyl)piperazine and Seizures
| Article | Year |
|---|---|
The anticonvulsant action of fluoxetine in substantia nigra is dependent upon endogenous serotonin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anticonvulsants; Bicuculline; Convulsants; Fencloni | 1996 |