lactic acid has been researched along with Seizures in 88 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In each case, severe metabolic lactic acidosis was identified through routine laboratory diagnostics." | 8.91 | [Lactic acidosis in the postictal state]. ( Admiraal-van de Pas, Y; van Rooij, FJ, 2015) |
| " Here, we present data using in vivo magnetic resonance spectroscopy (MRS) optimized for the detection of glutamate to identify changes that evolve following kainic acid (KA)-induced status epilepticus." | 7.75 | In vivo glutamate decline associated with kainic acid-induced status epilepticus. ( Crawford, EL; Hsu, O; Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Vinco, S; Zahr, NM, 2009) |
| "To determine whether lactic acidosis at birth in asphyxiated neonates could predict the grade of EEG encephalopathy by examining the relationship between time taken for the normalisation of lactate, severity of encephalopathy and seizure burden." | 7.74 | Persistent lactic acidosis in neonatal hypoxic-ischaemic encephalopathy correlates with EEG grade and electrographic seizure burden. ( Boylan, GB; Connolly, S; Fitzgerald, AP; Murphy, BP; Murray, DM; Ryan, CA, 2008) |
| "The present study has examined the anticonvulsant and neuroprotective effect of group II metabotropic glutamate receptor (mGluR) agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate (2R,4R-APDC) in the model of seizures induced in immature 12-day-old rats by bilateral intracerebroventricular infusion of dl-homocysteic acid (DL-HCA, 600 nmol/side)." | 7.73 | Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate. ( Druga, R; Folbergrová, J; Haugvicová, R; Kubová, H; Mares, P; Otáhal, J, 2005) |
| "We here reported the clinical course and therapeutic details of a 16-year-old girl with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) who had had five stroke-like episodes (two episodes were clinically mild, while the three subsequent episodes were severe)." | 7.72 | Beneficial effect of L-arginine for stroke-like episode in MELAS. ( Kubota, M; Momoi-Yoshida, M; Mori, M; Sakakihara, Y; Yamagata, T, 2004) |
| "Seizures were induced in 7-day-old rats by intraperitoneal injection of DL-homocysteine thiolactone." | 7.68 | Cerebral energy state of neonatal rats during seizures induced by homocysteine. ( Folbergrová, J, 1993) |
| ") in rats produced tremors and convulsions with lactic acidosis which was accompanied by depletion of glycogen and activation of glycogen phosphorylase activity in triceps and diaphragm muscles, 2 h after its administration." | 7.67 | Convulsions as the etiology of lactic acidosis in acute diazinon toxicity in rats. ( Husain, K; Matin, MA; Mirza, MA, 1987) |
| "Glycerol, the end product of phospholipid degradation, was measured in cat brains under pathophysiological conditions known to cause activation of lipolysis, namely, bicuculline-induced seizures, permanent focal cerebral ischemia (2 hr of middle cerebral artery occlusion), and global cerebral ischemia (15 min of complete cerebral ischemia with or without 2 hr of recirculation)." | 7.67 | Glycerol as an indicator of lipid degradation in bicuculline-induced seizures and experimental cerebral ischemia. ( Hossmann, KA; Paschen, W; van den Kerchhoff, W, 1986) |
| " In each case, severe metabolic lactic acidosis was identified through routine laboratory diagnostics." | 4.91 | [Lactic acidosis in the postictal state]. ( Admiraal-van de Pas, Y; van Rooij, FJ, 2015) |
| " Furthermore, real-time measurement of lactate and oxygen concentration dynamics concurrently with network electrical activity during status epilepticus induced by 4-aminopyridine (4-AP) demonstrated phasic changes in lactate levels that correlated with bursts of electrical activity, while tonic levels of lactate remained stable during seizures." | 4.84 | Amperometric bio-sensing of lactate and oxygen concurrently with local field potentials during status epilepticus. ( Barbosa, RM; Fernandes, E; Gerhardt, GA; Ledo, A, 2024) |
| "The synergic effect of regular exercise and resveratrol, a polyphenolic compound with potent antioxidant activity, was investigated against kainate-induced seizures and oxidative stress in mice." | 3.79 | The synergic effect of regular exercise and resveratrol on kainate-induced oxidative stress and seizure activity in mice. ( Kim, HJ; Kim, IK; Lee, J; Park, S; Song, W, 2013) |
| " Here, we present data using in vivo magnetic resonance spectroscopy (MRS) optimized for the detection of glutamate to identify changes that evolve following kainic acid (KA)-induced status epilepticus." | 3.75 | In vivo glutamate decline associated with kainic acid-induced status epilepticus. ( Crawford, EL; Hsu, O; Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Vinco, S; Zahr, NM, 2009) |
| "To determine whether lactic acidosis at birth in asphyxiated neonates could predict the grade of EEG encephalopathy by examining the relationship between time taken for the normalisation of lactate, severity of encephalopathy and seizure burden." | 3.74 | Persistent lactic acidosis in neonatal hypoxic-ischaemic encephalopathy correlates with EEG grade and electrographic seizure burden. ( Boylan, GB; Connolly, S; Fitzgerald, AP; Murphy, BP; Murray, DM; Ryan, CA, 2008) |
| "The present study has examined the anticonvulsant and neuroprotective effect of group II metabotropic glutamate receptor (mGluR) agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate (2R,4R-APDC) in the model of seizures induced in immature 12-day-old rats by bilateral intracerebroventricular infusion of dl-homocysteic acid (DL-HCA, 600 nmol/side)." | 3.73 | Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate. ( Druga, R; Folbergrová, J; Haugvicová, R; Kubová, H; Mares, P; Otáhal, J, 2005) |
| "We here reported the clinical course and therapeutic details of a 16-year-old girl with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) who had had five stroke-like episodes (two episodes were clinically mild, while the three subsequent episodes were severe)." | 3.72 | Beneficial effect of L-arginine for stroke-like episode in MELAS. ( Kubota, M; Momoi-Yoshida, M; Mori, M; Sakakihara, Y; Yamagata, T, 2004) |
| "We describe a patient with carnitine-acylcarnitine translocase deficiency (MIM 212138), who presented with neonatal generalized seizures, heart failure, and coma." | 3.70 | Carnitine-acylcarnitine translocase deficiency: metabolic consequences of an impaired mitochondrial carnitine cycle. ( Dorland, L; Duran, M; IJlst, L; Muntau, AC; Roscher, AA; Röschinger, W; Wanders, RJ, 2000) |
| " Arteriovenous measurements across brain revealed no significant loss of [14C]lactate in normal rats or rats with bicuculline-induced seizures." | 3.69 | Optimizing the measurement of regional cerebral glucose consumption with [6-14C]glucose. ( DeJoseph, MR; Hawkins, PA; Hawkins, RA; Mans, AM; Viña, JR, 1994) |
| " Infarcts in substantia nigra pars reticulata were evoked by prolonged pilocarpine-induced status epilepticus." | 3.68 | Immunohistochemical studies with antibodies to neurofilament proteins on axonal damage in experimental focal lesions in rat. ( Bellander, BM; Ingvar, M; Meller, D; Schmidt-Kastner, R, 1993) |
| "Seizures were induced in 7-day-old rats by intraperitoneal injection of DL-homocysteine thiolactone." | 3.68 | Cerebral energy state of neonatal rats during seizures induced by homocysteine. ( Folbergrová, J, 1993) |
| ") in rats produced tremors and convulsions with lactic acidosis which was accompanied by depletion of glycogen and activation of glycogen phosphorylase activity in triceps and diaphragm muscles, 2 h after its administration." | 3.67 | Convulsions as the etiology of lactic acidosis in acute diazinon toxicity in rats. ( Husain, K; Matin, MA; Mirza, MA, 1987) |
| "To examine the hypothesis that hypoglycemia has an adverse effect on brain energy state during seizure, neonatal dogs were subjected to bicuculline-induced seizure while hyperglycemic, normoglycemic, or hypoglycemic." | 3.67 | In vivo 31P and in vitro 1H nuclear magnetic resonance study of hypoglycemia during neonatal seizure. ( Briggs, RW; Cowan, BE; Dunham, SL; Novotny, E; Petroff, OA; Young, RS, 1987) |
| "Glycerol, the end product of phospholipid degradation, was measured in cat brains under pathophysiological conditions known to cause activation of lipolysis, namely, bicuculline-induced seizures, permanent focal cerebral ischemia (2 hr of middle cerebral artery occlusion), and global cerebral ischemia (15 min of complete cerebral ischemia with or without 2 hr of recirculation)." | 3.67 | Glycerol as an indicator of lipid degradation in bicuculline-induced seizures and experimental cerebral ischemia. ( Hossmann, KA; Paschen, W; van den Kerchhoff, W, 1986) |
| "Differentiating epileptic seizures from other causes of Transient Loss of Consciousness (TLOC) remains a challenge in the Emergency Department (ED), where it may lead to erroneous administration of anti-epileptic drugs." | 2.82 | Utility of serum lactate on differential diagnosis of seizure-like activity: A systematic review and meta-analysis. ( Martinez, S; Patel, J; Pourmand, A; Tran, QK; Wright, H, 2022) |
| "Repetitively firing neurons during seizures accelerate glycolysis to meet energy demand, which leads to the accumulation of extracellular glycolytic by-product lactate." | 1.91 | Glycolysis regulates neuronal excitability via lactate receptor, HCA1R. ( Kapur, J; Kasprzak, I; Skwarzynska, D; Sun, H; Williamson, J, 2023) |
| "A single seizure and SE stimulate lactate production." | 1.91 | Glycolytic lactate production supports status epilepticus in experimental animals. ( Kapur, J; Kasprzak, I; Sharma, S; Skwarzynska, D; Sun, H; Williamson, J, 2023) |
| "Focal cortical dysplasia (FCD) is associated with blood-brain barrier (BBB) dysfunction in patients with difficult-to-treat epilepsy." | 1.72 | Cortical Dysplasia in Rats Provokes Neurovascular Alterations, GLUT1 Dysfunction, and Metabolic Disturbances That Are Sustained Post-Seizure Induction. ( Ghosh, C; Hossain, M; Liu, X; Myers, R; Najm, IM; Nemeth, M; O'Connor, C; Williams, S, 2022) |
| "Patients with an ER diagnosis of epileptic seizures, psychogenic non-epileptic seizure (PNES), and syncope were selected for analysis." | 1.72 | Clinical utility of serum prolactin and lactate concentrations to differentiate epileptic seizures from non-epileptic attacks in the emergency room. ( Shimmura, M; Takase, KI, 2022) |
| "A total of 383 cases of transient loss of consciousness were identified and categorized as tonic-clonic seizure (TCS), other seizure, syncope, or other cause, according to the final diagnosis in the electronic medical records system." | 1.62 | Prehospital lactate levels in blood as a seizure biomarker: A multi-center observational study. ( Axelsson, C; Edelvik Tranberg, A; Herlitz, J; Höglind, R; Magnusson, C; Wennberg, P; Zelano, J, 2021) |
| "Dogs with focal seizures had higher CSF lactate concentrations than did those with generalized seizures (P = ." | 1.56 | Cerebrospinal fluid lactate concentrations in dogs with seizure disorders. ( Early, PJ; Green, L; Guevar, J; Lau, J; Lee, CS; Mariani, CL; Muñana, KR; Nye, CJ; Olby, NJ; Ruterbories, L; Tokarz, DA; Zidan, N, 2020) |
| "Hypophosphatemia was the only independent predictor of TC seizures, even in later samples (>2 h)." | 1.56 | Hypophosphatemia compared to classical biomarkers of tonic clonic seizures. ( Barbella, G; Barras, P; Novy, J; Rossetti, AO, 2020) |
| "Our data suggest that seizure semiology might impact CSF profiles." | 1.51 | Cerebrospinal fluid changes following epileptic seizures unrelated to inflammation. ( Hannich, M; Saathoff, N; Süße, M; von Podewils, F, 2019) |
| "Among them, 23." | 1.51 | Blood lactate measurement within the emergency department: A two-year retrospective analysis. ( Contenti, J; Ferrari, P; Lemoel, F; Levraut, J; Occelli, C, 2019) |
| "Regarding the first hour after the seizure, we identify a cut-off for serum lactate of 2." | 1.48 | Early postictal serum lactate concentrations are superior to serum creatine kinase concentrations in distinguishing generalized tonic-clonic seizures from syncopes. ( Brokmann, JC; Dafotakis, M; Heckelmann, J; Litmathe, J; Matz, O; Schulz, JB; Willmes, K; Zechbauer, S, 2018) |
| "The hallmark of pediatric cerebral malaria (CM) is sequestration of parasitized red blood cells in the cerebral microvasculature." | 1.48 | 1.5 Tesla Magnetic Resonance Imaging to Investigate Potential Etiologies of Brain Swelling in Pediatric Cerebral Malaria. ( Birbeck, GL; Glover, SJ; Haacke, EM; Hammond, CA; Kampondeni, SD; Lishimpi, K; Milner, DA; Mwenechanya, M; Potchen, MJ; Seydel, KB; Sinyangwe, SS; Taylor, TE; Utriainen, D; Zeli, E, 2018) |
| "These 2 patients presented with seizures." | 1.46 | Magnetic Resonance Spectroscopy Findings in Patients with Dural Arteriovenous Fistulas: Three Case Reports. ( Fujita, A; Hosoda, K; Kohmura, E; Kohta, M; Nagashima, H; Sasayama, T; Tanaka, J; Tanaka, K, 2017) |
| "Epilepsy is a chronic neurological disorder that affects approximately 50 million people worldwide." | 1.46 | Reduction of epileptiform activity in ketogenic mice: The role of monocarboxylate transporters. ( Becker, HM; Deitmer, JW; Forero-Quintero, LS, 2017) |
| "The most frequent symptoms were seizures (76%), short stature (73%), elevated plasma lactate (70%), abnormal magnetic resonance imaging/computed tomography (MRI/CT) changes (68%), vomiting (55%), decreased vision (52%), headache (50%), and muscle weakness (48%)." | 1.43 | Clinical and Molecular Characteristics in 100 Chinese Pediatric Patients with m.3243A>G Mutation in Mitochondrial DNA. ( Liu, H; Liu, Y; Ma, YN; Qi, Y; Xia, CY; Zhang, YC, 2016) |
| "In TBI patients, seizures and periodic discharges are one mechanism for metabolic crisis, and hence represent a therapeutic target for future study." | 1.43 | Metabolic crisis occurs with seizures and periodic discharges after brain trauma. ( Buitrago-Blanco, M; Claassen, J; McArthur, D; Nuwer, M; Prins, M; Tu, B; Tubi, M; Velazquez, AG; Vespa, P, 2016) |
| "Compared to the controls, patients with seizures had higher levels of lactate, butanoic acid, proline and glutamate and lower levels of palmitic acid, linoleic acid, elaidic acid, trans-13-octadecenoic acid, stearic acid, citrate, cysteine, glutamine, asparagine, and glyceraldehyde in the serum." | 1.43 | GC-MS-Based metabolomics discovers a shared serum metabolic characteristic among three types of epileptic seizures. ( Kong, J; Lai, M; Wang, D; Wang, X; Wu, J, 2016) |
| "Different seizure types influenced all parameters except for the cell count: In status epilepticus highest, in simple partial seizures lowest values were seen." | 1.42 | Effect of epileptic seizures on the cerebrospinal fluid--A systematic retrospective analysis. ( Brettschneider, J; Fauser, S; Hoppner, AC; Jobs, C; Kerling, F; Tumani, H, 2015) |
| "Five patients became seizure-free with the onset of ketosis, and anticonvulsants were discontinued." | 1.42 | The Effects of Ketogenic Diet on Seizures, Cognitive Functions, and Other Neurological Disorders in Classical Phenotype of Glucose Transporter 1 Deficiency Syndrome. ( Bayram, AK; Çağlayan, AO; Canpolat, M; Gumus, H; Kardas, F; Kendirci, M; Kumandas, S; Per, H, 2015) |
| "We investigated the association between hepatic encephalopathy (HE) scores, abnormal EEG or neuroimaging, and short-term outcome." | 1.40 | EEG abnormalities are associated with increased risk of transplant or poor outcome in children with acute liver failure. ( Alonso, E; Goldstein, J; Grimason, M; Hussain, E; Smith, CM; Wainwright, MS; Whitington, PF, 2014) |
| "In two chemically induced seizure models, mice with reduced tau protein had less severe seizures than control mice." | 1.39 | Antisense reduction of tau in adult mice protects against seizures. ( Bennett, CF; Chen, G; Cirrito, JR; DeVos, SL; Goncharoff, DK; Holtzman, DM; Kebodeaux, CS; Maloney, SE; Miller, TM; Rigo, F; Schuler, DR; Stewart, FR; Wozniak, DF; Yamada, K, 2013) |
| " The results of this study demonstrate a plausible novel anticonvulsant activity of β-carotene at a low dose of 2 mg/kg, with brain-targeted nanodelivery, thus increasing its bioavailability and stability." | 1.38 | Plausible antioxidant biomechanics and anticonvulsant pharmacological activity of brain-targeted β-carotene nanoparticles. ( Ahmed, B; Khan, M; Khan, RA; Yusuf, M, 2012) |
| "Embolism is responsible for half of cerebral infarctions, yet few animal models were developed due to the unpredictability of the embolus-induced infarcts." | 1.37 | Characterization of the pattern of ischemic stroke induced by artificial particle embolization in the rat brain. ( Kuo, YM; Tsai, MJ; Tsai, YH, 2011) |
| "However, generalized tonic-clonic seizures produced by sound stimulation resulted in a decrease in muscle glycogen content." | 1.35 | Peripheral glucose metabolism is altered by epileptic seizures. ( Borges, EL; Braga, AA; Doretto, MC; Lima, MP; Neves, MJ; Pereira, FK; Pesquero, JL, 2008) |
| "These four children all had seizure activity and abnormal initial neurological examinations and required admission to the PICU." | 1.33 | Elevated lactate as an early marker of brain injury in inflicted traumatic brain injury. ( Ball, WS; Care, M; Cecil, KM; Makoroff, KL, 2005) |
| "Her symptoms consisted of a few convulsions between 2." | 1.33 | [Glutaric aciduria type 1 with normal evolution: follow-up of one case until adult age]. ( Garcia-Segura, JM; Merinero, B; Pascual-Castroviejo, I; Pascual-Pascual, SI; Ugarte, M; Velazquez, R; Viaño, J, 2005) |
| "The conditions included seizures, inflammatory changes, and proven metabolic disorders." | 1.33 | The significance of elevated CSF lactate. ( Chow, SL; Clayton, PT; Cleary, MA; Leonard, JV; Rooney, ZJ, 2005) |
| "Hashimoto's encephalopathy should be considered in cases of unexplained encephalopathy presenting to the intensive care unit." | 1.32 | Hashimoto's encephalopathy: an unusual cause of seizures in the intensive care unit. ( Janes, SE; Santosh, B; Thomas, D; Vyas, H, 2004) |
| "During seizures SMABF fell significantly (8." | 1.32 | The role of the sympathetic nervous system in postasphyxial intestinal hypoperfusion in the pre-term sheep fetus. ( Bennet, L; Gunn, AJ; Heineman, E; Quaedackers, JS; Roelfsema, V, 2004) |
| "During seizures, ATP and PCr values declined significantly below their homologous controls." | 1.31 | Prolonged neonatal seizures exacerbate hypoxic-ischemic brain damage: correlation with cerebral energy metabolism and excitatory amino acid release. ( Armstrong, EA; Miyashita, H; Wirrell, EC; Yager, JY, 2002) |
| "During 30-min clonic seizures, mean blood pressure, plasma glucose and paO2 did not decrease and plasma lactate doubled." | 1.27 | Generalized seizures deplete brain energy reserves in normoxemic newborn monkeys. ( Dwyer, BE; Fujikawa, DG; Vannucci, RC; Wasterlain, CG, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (15.91) | 18.7374 |
| 1990's | 7 (7.95) | 18.2507 |
| 2000's | 26 (29.55) | 29.6817 |
| 2010's | 26 (29.55) | 24.3611 |
| 2020's | 15 (17.05) | 2.80 |
| Authors | Studies |
|---|---|
| Süße, M | 2 |
| Gag, K | 1 |
| Hamann, L | 1 |
| Hannich, MJ | 1 |
| von Podewils, F | 2 |
| Shimmura, M | 1 |
| Takase, KI | 1 |
| Brody, EI | 1 |
| Genuini, M | 1 |
| Auvin, S | 1 |
| Lodé, N | 1 |
| Brunet, SR | 1 |
| Ghosh, C | 1 |
| Myers, R | 1 |
| O'Connor, C | 1 |
| Williams, S | 1 |
| Liu, X | 1 |
| Hossain, M | 1 |
| Nemeth, M | 1 |
| Najm, IM | 2 |
| Jean, J | 1 |
| Christodoulou, E | 1 |
| Gai, X | 1 |
| Tamrazi, B | 1 |
| Vera, M | 1 |
| Mitchell, WG | 1 |
| Schmidt, RJ | 1 |
| Martinez, S | 2 |
| Patel, J | 2 |
| Abdelmonem, A | 1 |
| AlRemeithi, R | 1 |
| Pourmand, A | 2 |
| Tran, QK | 1 |
| Wright, H | 1 |
| Skwarzynska, D | 2 |
| Sun, H | 2 |
| Williamson, J | 2 |
| Kasprzak, I | 2 |
| Kapur, J | 2 |
| Namayanja, C | 1 |
| Eregu, EEI | 1 |
| Ongodia, P | 1 |
| Okalebo, CB | 1 |
| Okiror, W | 1 |
| Okello, F | 1 |
| Okibure, A | 1 |
| Paasi, G | 1 |
| Kakungulu, H | 1 |
| Grace, A | 1 |
| Muhindo, R | 1 |
| Banks, D | 1 |
| Martin, C | 1 |
| Taylor-Robinson, S | 1 |
| Olupot-Olupot, P | 1 |
| Sharma, S | 1 |
| Fernandes, E | 1 |
| Ledo, A | 1 |
| Gerhardt, GA | 1 |
| Barbosa, RM | 1 |
| Ueno, H | 1 |
| Iizuka, T | 1 |
| Tagane, Y | 1 |
| Yamasaki, F | 1 |
| Akiyama, Y | 1 |
| Hosomi, N | 1 |
| Maruyama, H | 1 |
| Barbella, G | 1 |
| Barras, P | 1 |
| Rossetti, AO | 1 |
| Novy, J | 1 |
| Mariani, CL | 1 |
| Nye, CJ | 1 |
| Ruterbories, L | 1 |
| Tokarz, DA | 1 |
| Green, L | 1 |
| Lau, J | 1 |
| Zidan, N | 1 |
| Early, PJ | 1 |
| Muñana, KR | 1 |
| Olby, NJ | 1 |
| Lee, CS | 1 |
| Guevar, J | 1 |
| Magnusson, C | 1 |
| Herlitz, J | 1 |
| Höglind, R | 1 |
| Wennberg, P | 1 |
| Edelvik Tranberg, A | 1 |
| Axelsson, C | 1 |
| Zelano, J | 1 |
| Nagashima, H | 1 |
| Fujita, A | 1 |
| Tanaka, J | 1 |
| Kohta, M | 1 |
| Sasayama, T | 1 |
| Tanaka, K | 1 |
| Hosoda, K | 1 |
| Kohmura, E | 1 |
| McDonald, TS | 1 |
| Borges, K | 1 |
| Forero-Quintero, LS | 1 |
| Deitmer, JW | 1 |
| Becker, HM | 1 |
| Matz, O | 2 |
| Heckelmann, J | 1 |
| Zechbauer, S | 2 |
| Litmathe, J | 2 |
| Brokmann, JC | 1 |
| Willmes, K | 2 |
| Schulz, JB | 2 |
| Dafotakis, M | 2 |
| Potchen, MJ | 1 |
| Kampondeni, SD | 1 |
| Seydel, KB | 1 |
| Haacke, EM | 1 |
| Sinyangwe, SS | 1 |
| Mwenechanya, M | 1 |
| Glover, SJ | 1 |
| Milner, DA | 1 |
| Zeli, E | 1 |
| Hammond, CA | 1 |
| Utriainen, D | 1 |
| Lishimpi, K | 1 |
| Taylor, TE | 1 |
| Birbeck, GL | 1 |
| Contenti, J | 1 |
| Occelli, C | 1 |
| Lemoel, F | 1 |
| Ferrari, P | 1 |
| Levraut, J | 1 |
| Saathoff, N | 1 |
| Hannich, M | 1 |
| DeVos, SL | 1 |
| Goncharoff, DK | 1 |
| Chen, G | 1 |
| Kebodeaux, CS | 1 |
| Yamada, K | 1 |
| Stewart, FR | 1 |
| Schuler, DR | 1 |
| Maloney, SE | 1 |
| Wozniak, DF | 1 |
| Rigo, F | 1 |
| Bennett, CF | 1 |
| Cirrito, JR | 1 |
| Holtzman, DM | 1 |
| Miller, TM | 1 |
| Ching, CK | 1 |
| Mak, CM | 1 |
| Au, KM | 1 |
| Chan, KY | 1 |
| Yuen, YP | 1 |
| Yau, EK | 1 |
| Ma, LC | 1 |
| Chow, HL | 1 |
| Chan, AY | 1 |
| Hussain, E | 1 |
| Grimason, M | 1 |
| Goldstein, J | 1 |
| Smith, CM | 1 |
| Alonso, E | 1 |
| Whitington, PF | 1 |
| Wainwright, MS | 1 |
| Ruban, A | 1 |
| Biton, IE | 1 |
| Markovich, A | 1 |
| Mirelman, D | 1 |
| Tumani, H | 1 |
| Jobs, C | 1 |
| Brettschneider, J | 1 |
| Hoppner, AC | 1 |
| Kerling, F | 1 |
| Fauser, S | 1 |
| Gumus, H | 1 |
| Bayram, AK | 1 |
| Kardas, F | 1 |
| Canpolat, M | 1 |
| Çağlayan, AO | 1 |
| Kumandas, S | 1 |
| Kendirci, M | 1 |
| Per, H | 1 |
| Chatzikonstantinou, A | 1 |
| Ebert, AD | 1 |
| Hennerici, MG | 1 |
| van Rooij, FJ | 1 |
| Admiraal-van de Pas, Y | 1 |
| Vespa, P | 1 |
| Tubi, M | 1 |
| Claassen, J | 1 |
| Buitrago-Blanco, M | 1 |
| McArthur, D | 1 |
| Velazquez, AG | 1 |
| Tu, B | 1 |
| Prins, M | 1 |
| Nuwer, M | 1 |
| Zdebik, C | 1 |
| Bündgens, L | 1 |
| Wang, D | 1 |
| Wang, X | 1 |
| Kong, J | 1 |
| Wu, J | 1 |
| Lai, M | 1 |
| Xia, CY | 1 |
| Liu, Y | 1 |
| Liu, H | 1 |
| Zhang, YC | 1 |
| Ma, YN | 1 |
| Qi, Y | 1 |
| Simister, RJ | 1 |
| McLean, MA | 1 |
| Salmenpera, TM | 1 |
| Barker, GJ | 1 |
| Duncan, JS | 1 |
| Lim, CC | 1 |
| Gan, R | 1 |
| Chan, CL | 1 |
| Tan, AW | 1 |
| Khoo, JJ | 1 |
| Chia, SY | 1 |
| Kao, SL | 1 |
| Abisheganaden, J | 1 |
| Sitoh, YY | 1 |
| Zhao, Y | 1 |
| Fung, C | 1 |
| Shin, D | 1 |
| Shin, BC | 1 |
| Thamotharan, S | 1 |
| Sankar, R | 1 |
| Ehninger, D | 1 |
| Silva, A | 1 |
| Devaskar, SU | 1 |
| Zahr, NM | 1 |
| Crawford, EL | 1 |
| Hsu, O | 1 |
| Vinco, S | 1 |
| Mayer, D | 1 |
| Rohlfing, T | 1 |
| Sullivan, EV | 1 |
| Pfefferbaum, A | 1 |
| Verity, CM | 1 |
| Winstone, AM | 1 |
| Stellitano, L | 1 |
| Krishnakumar, D | 1 |
| Will, R | 1 |
| McFarland, R | 1 |
| KLEIN, JR | 1 |
| OLSEN, NS | 1 |
| Tsai, MJ | 1 |
| Tsai, YH | 1 |
| Kuo, YM | 1 |
| Joardar, S | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An MRI Ancillary Study of a Malaria Fever Randomized Controlled Trial (RCT)[NCT05746819] | 256 participants (Anticipated) | Observational | 2021-01-02 | Enrolling by invitation | |||
| Role of Glutamate-mediate Excitotoxicity in Invasion and Progression Processes of Glioblastoma Multiforme[NCT05775458] | 50 participants (Anticipated) | Observational | 2020-06-01 | Recruiting | |||
| Exogenous Sodium Lactate Infusion in Traumatic Brain Injury (ELI-TBI)[NCT02776488] | Phase 2 | 0 participants (Actual) | Interventional | 2020-09-30 | Withdrawn (stopped due to The manufacturer of sodium lactate has stopped making the medication) | ||
| Lactate Compared to Creatine Kinase as Diagnostic Marker in Generalized Epileptic Seizure[NCT02926703] | 85 participants (Actual) | Observational | 2015-11-30 | Completed | |||
| Serum Lactate in Convulsive Syncopes Compared to Non-convulsive Syncopes[NCT03062683] | 100 participants (Anticipated) | Observational | 2017-01-01 | Recruiting | |||
| The Effect of Standardizing the Definition and Approach to a Clinically Significant Cardiopulmonary Event in Infants Less Than 30 Weeks on Length of Stay[NCT03414671] | 160 participants (Actual) | Observational | 2018-06-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for lactic acid and Seizures
| Article | Year |
|---|---|
Utility of serum lactate on differential diagnosis of seizure-like activity: A systematic review and meta-analysis.
Topics: Adult; Diagnosis, Differential; Electroencephalography; Epilepsy; Humans; Lactic Acid; Prospective S | 2022 |
[Lactic acidosis in the postictal state].
Topics: Acidosis, Lactic; Adult; Emergency Service, Hospital; Epilepsy; Humans; Incidence; Lactic Acid; Male | 2015 |
Lactic acidosis in the brain: occurrence, triggering mechanisms and pathophysiological importance.
Topics: Acidosis; Animals; Blood Glucose; Brain; Brain Ischemia; Carbon Dioxide; Glucose; Hypoxia, Brain; In | 1982 |
85 other studies available for lactic acid and Seizures
| Article | Year |
|---|---|
Time dependency of CSF cell count, lactate and blood-CSF barrier dysfunction after epileptic seizures and status epilepticus.
Topics: Cell Count; Epilepsy; Humans; Lactic Acid; Seizures; Status Epilepticus | 2022 |
Clinical utility of serum prolactin and lactate concentrations to differentiate epileptic seizures from non-epileptic attacks in the emergency room.
Topics: Diagnosis, Differential; Electroencephalography; Emergency Service, Hospital; Humans; Lactic Acid; P | 2022 |
Prehospital capillary lactate in children differentiates epileptic seizure from febrile seizure, syncope, and psychogenic nonepileptic seizure.
Topics: Child; Diagnosis, Differential; Electroencephalography; Emergency Medical Services; Humans; Lactic A | 2022 |
Cortical Dysplasia in Rats Provokes Neurovascular Alterations, GLUT1 Dysfunction, and Metabolic Disturbances That Are Sustained Post-Seizure Induction.
Topics: Animals; Blood-Brain Barrier; Epilepsy; Glucose; Glucose Transporter Type 1; Lactic Acid; Malformati | 2022 |
m.3685T > C is a novel mitochondrial DNA variant that causes Leigh syndrome.
Topics: DNA, Mitochondrial; Female; Humans; Lactic Acid; Leigh Disease; Mitochondrial Diseases; Mutation; Se | 2022 |
Use of serum prolactin and lactic acid as a biomarker for epileptic and non-epileptic seizures in the emergency room.
Topics: Biomarkers; Emergency Service, Hospital; Epilepsy; Humans; Lactic Acid; Prolactin; Seizures | 2022 |
Glycolysis regulates neuronal excitability via lactate receptor, HCA1R.
Topics: Animals; Hippocampus; Lactic Acid; Mice; Mice, Knockout; Neurons; Pyramidal Cells; Seizures | 2023 |
Unusual clinical spectra of childhood severe malaria during malaria epidemic in eastern Uganda: a prospective study.
Topics: Adolescent; Anemia; Blackwater Fever; Child; Child, Preschool; Epidemics; Female; Humans; Infant; Ja | 2023 |
Glycolytic lactate production supports status epilepticus in experimental animals.
Topics: Animals; Glucose; Glycolysis; Humans; Lactic Acid; Mice; Pyruvates; Seizures; Status Epilepticus | 2023 |
Amperometric bio-sensing of lactate and oxygen concurrently with local field potentials during status epilepticus.
Topics: 4-Aminopyridine; Animals; Biosensing Techniques; Brain; Epilepsy; Humans; Lactic Acid; Oxygen; Rats; | 2024 |
Focal hyperperfusion and elevated lactate in the cerebral lesions with anti-GABAaR encephalitis: A serial MRI study.
Topics: Aged; Brain; Encephalitis; Female; Hashimoto Disease; Humans; Lactic Acid; Magnetic Resonance Imagin | 2020 |
Hypophosphatemia compared to classical biomarkers of tonic clonic seizures.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Creatine Kinase; Diagnosis, Differential; Em | 2020 |
Cerebrospinal fluid lactate concentrations in dogs with seizure disorders.
Topics: Animals; Dog Diseases; Dogs; Epilepsy; Humans; Lactic Acid; Seizures; Status Epilepticus | 2020 |
Prehospital lactate levels in blood as a seizure biomarker: A multi-center observational study.
Topics: Adult; Aged; Biomarkers; Diagnosis, Differential; Emergency Medical Services; Female; Humans; Lactic | 2021 |
Magnetic Resonance Spectroscopy Findings in Patients with Dural Arteriovenous Fistulas: Three Case Reports.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Central Nervous System Vascular Malformations; Cerebral Angi | 2017 |
Impaired hippocampal glucose metabolism during and after flurothyl-induced seizures in mice: Reduced phosphorylation coincides with reduced activity of pyruvate dehydrogenase.
Topics: Alanine; Amino Acids; Animals; Antioxidants; Blood Glucose; Citric Acid Cycle; Flurothyl; Gas Chroma | 2017 |
Reduction of epileptiform activity in ketogenic mice: The role of monocarboxylate transporters.
Topics: 3-Hydroxybutyric Acid; Animals; Astrocytes; Brain; Diet, Ketogenic; Disease Models, Animal; Epilepsy | 2017 |
Early postictal serum lactate concentrations are superior to serum creatine kinase concentrations in distinguishing generalized tonic-clonic seizures from syncopes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Creatine Kinase; Diagnosis, Differential; Em | 2018 |
1.5 Tesla Magnetic Resonance Imaging to Investigate Potential Etiologies of Brain Swelling in Pediatric Cerebral Malaria.
Topics: Adolescent; Blood Glucose; Brain Diseases; Child; Child, Preschool; Female; Gadolinium; Humans; Infa | 2018 |
Blood lactate measurement within the emergency department: A two-year retrospective analysis.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Emergency Service, Hospital; Female; France; Hospital Mo | 2019 |
Cerebrospinal fluid changes following epileptic seizures unrelated to inflammation.
Topics: Adult; Aged; Aged, 80 and over; Albumins; Blood-Brain Barrier; Brain; Electroencephalography; Epilep | 2019 |
Antisense reduction of tau in adult mice protects against seizures.
Topics: Age Factors; Animals; Anticonvulsants; Central Nervous System; Convulsants; Disease Models, Animal; | 2013 |
A patient with congenital hyperlactataemia and Leigh syndrome: an uncommon mitochondrial variant.
Topics: Acidosis, Lactic; DNA, Mitochondrial; Female; Humans; Infant; Lactic Acid; Leigh Disease; Pyruvic Ac | 2013 |
EEG abnormalities are associated with increased risk of transplant or poor outcome in children with acute liver failure.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Child; Child, Preschool; Electroencephalography; | 2014 |
MRS of brain metabolite levels demonstrates the ability of scavenging of excess brain glutamate to protect against nerve agent induced seizures.
Topics: Animals; Aspartate Aminotransferases; Brain; Glutamic Acid; Humans; Lactic Acid; Magnetic Resonance | 2015 |
Effect of epileptic seizures on the cerebrospinal fluid--A systematic retrospective analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albumins; Cell Count; Cerebrospinal Fluid; Epilepsy; Fem | 2015 |
The Effects of Ketogenic Diet on Seizures, Cognitive Functions, and Other Neurological Disorders in Classical Phenotype of Glucose Transporter 1 Deficiency Syndrome.
Topics: Adolescent; Biomarkers; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Child; Child, Prescho | 2015 |
Cerebrospinal fluid findings after epileptic seizures.
Topics: Adult; Aged; Brain; Electroencephalography; Epilepsy; Female; Glucose; Humans; Lactic Acid; Magnetic | 2015 |
Metabolic crisis occurs with seizures and periodic discharges after brain trauma.
Topics: Adult; Aged; Aged, 80 and over; Brain Injuries; Electroencephalography; Female; Humans; Lactic Acid; | 2016 |
Lactate as a diagnostic marker in transient loss of consciousness.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Lactic Acid; Male; Middle Aged; Psychoph | 2016 |
Lactate as a diagnostic marker in transient loss of consciousness.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Lactic Acid; Male; Middle Aged; Psychoph | 2016 |
Lactate as a diagnostic marker in transient loss of consciousness.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Lactic Acid; Male; Middle Aged; Psychoph | 2016 |
Lactate as a diagnostic marker in transient loss of consciousness.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Lactic Acid; Male; Middle Aged; Psychoph | 2016 |
GC-MS-Based metabolomics discovers a shared serum metabolic characteristic among three types of epileptic seizures.
Topics: Adolescent; Adult; Aged, 80 and over; Area Under Curve; Biomarkers; Epilepsies, Partial; Epilepsy, G | 2016 |
Clinical and Molecular Characteristics in 100 Chinese Pediatric Patients with m.3243A>G Mutation in Mitochondrial DNA.
Topics: Adolescent; Age of Onset; Asian People; Chi-Square Distribution; Child; Child, Preschool; DNA, Mitoc | 2016 |
The effect of epileptic seizures on proton MRS visible neurochemical concentrations.
Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Data Interpretation, Statistical; Dipeptid | 2008 |
Severe hypoglycemia associated with an illegal sexual enhancement product adulterated with glibenclamide: MR imaging findings.
Topics: Adult; Aged; Blood Volume; Brain; Cerebrovascular Disorders; Coma; Consciousness Disorders; Diffusio | 2009 |
Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Cell Adhesion Molecules, Neuronal; Child; Child | 2010 |
In vivo glutamate decline associated with kainic acid-induced status epilepticus.
Topics: Analysis of Variance; Animals; Aspartic Acid; Disease Progression; Glutamic Acid; Hippocampus; Image | 2009 |
The clinical presentation of mitochondrial diseases in children with progressive intellectual and neurological deterioration: a national, prospective, population-based study.
Topics: Adolescent; Basal Ganglia; Child; Child, Preschool; Developmental Disabilities; Diagnosis, Different | 2010 |
Effect of convulsive activity upon the concentration of brain glucose, glycogen, lactate, and phosphates.
Topics: Brain; Glucose; Glycogen; Lactates; Lactic Acid; Neurochemistry; Phosphates; Seizures | 1947 |
Characterization of the pattern of ischemic stroke induced by artificial particle embolization in the rat brain.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Chitin; Embolism; | 2011 |
Unilateral basal-ganglia involvement likely due to valproate-induced hyperammonemic encephalopathy.
Topics: Anticonvulsants; Basal Ganglia; Brain Diseases; Child, Preschool; Diffusion Magnetic Resonance Imagi | 2012 |
Pontocerebellar hypoplasia type 6 caused by mutations in RARS2: definition of the clinical spectrum and molecular findings in five patients.
Topics: Arginine-tRNA Ligase; Cerebellum; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Infan | 2013 |
Plausible antioxidant biomechanics and anticonvulsant pharmacological activity of brain-targeted β-carotene nanoparticles.
Topics: Analysis of Variance; Animals; Anticonvulsants; Antioxidants; beta Carotene; Brain; Calorimetry, Dif | 2012 |
The synergic effect of regular exercise and resveratrol on kainate-induced oxidative stress and seizure activity in mice.
Topics: Anaerobic Threshold; Animals; Antioxidants; Body Weight; Catalase; Kainic Acid; Lactic Acid; Male; M | 2013 |
Prolonged neonatal seizures exacerbate hypoxic-ischemic brain damage: correlation with cerebral energy metabolism and excitatory amino acid release.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Animals, Newborn; Blood Glucose; Excitatory | 2002 |
Creatine protects against the convulsive behavior and lactate production elicited by the intrastriatal injection of methylmalonate.
Topics: Animals; Behavior, Animal; Corpus Striatum; Creatine; Disease Models, Animal; Dizocilpine Maleate; D | 2003 |
Changes in peripheral energy metabolism during audiogenic seizures in rats.
Topics: Acoustic Stimulation; Adipose Tissue; Adrenergic beta-Agonists; Animals; Blood Glucose; Energy Metab | 2003 |
CHRONIC ACIDOSIS DUE TO AN ERROR IN LACTATE AND PYRUVATE METABOLISM. REPORT OF TWO CASES.
Topics: Acetoacetates; Acidosis; Blood; Blood Gas Analysis; Carbohydrate Metabolism; Carbohydrate Metabolism | 1964 |
Alexander disease with serial MRS and a new mutation in the glial fibrillary acidic protein gene.
Topics: Acidosis, Respiratory; Alexander Disease; Basal Ganglia; Choline; Creatine; Disease Progression; DNA | 2003 |
The role of the sympathetic nervous system in postasphyxial intestinal hypoperfusion in the pre-term sheep fetus.
Topics: Animals; Asphyxia; Blood Gas Analysis; Blood Glucose; Blood Pressure; Electroencephalography; Electr | 2004 |
Beneficial effect of L-arginine for stroke-like episode in MELAS.
Topics: Adolescent; Arginine; Brain; Brain Ischemia; Drug Therapy, Combination; Energy Metabolism; Female; G | 2004 |
Hashimoto's encephalopathy: an unusual cause of seizures in the intensive care unit.
Topics: Adolescent; Autoantibodies; Brain Diseases; Cognition Disorders; Female; Glucocorticoids; Humans; In | 2004 |
Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate.
Topics: Amino Acids; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Brain; Brain Chemistry; B | 2005 |
Elevated lactate as an early marker of brain injury in inflicted traumatic brain injury.
Topics: Aspartic Acid; Brain Chemistry; Brain Injuries; Critical Care; Female; Fractures, Bone; Frontal Lobe | 2005 |
[Glutaric aciduria type 1 with normal evolution: follow-up of one case until adult age].
Topics: Basal Ganglia; Brain; Brain Chemistry; Brain Diseases, Metabolic, Inborn; Carnitine; Cells, Cultured | 2005 |
Chemical shift imaging and localised magnetic resonance spectroscopy in full-term asphyxiated neonates.
Topics: Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Brain; Choline; Creatine; Electroencephalography; F | 2005 |
Brain metabolism of exogenous pyruvate.
Topics: Animals; Behavior, Animal; Blood; Brain; Dose-Response Relationship, Drug; Electroencephalography; E | 2005 |
The significance of elevated CSF lactate.
Topics: Acidosis, Lactic; Biomarkers; Child; Diagnosis, Differential; Humans; Inflammation; Lactic Acid; Met | 2005 |
Case records of the Massachusetts General Hospital. Case 36-2005. A 61-year-old woman with seizure, disturbed gait, and altered mental status.
Topics: Aphasia; Biopsy; Brain; Confusion; Diagnosis, Differential; Fatal Outcome; Female; Gait Disorders, N | 2005 |
Respiratory chain deficiency in a female with Aicardi-Goutières syndrome.
Topics: Basal Ganglia; Calcinosis; Chromatography, Gas; Dementia, Vascular; Female; Humans; Interferon-alpha | 2006 |
The effect of cerebral hypothermia on white and grey matter injury induced by severe hypoxia in preterm fetal sheep.
Topics: Animals; Antigens, Surface; Blood Flow Velocity; Blood Glucose; Blood Pressure; Body Temperature; Br | 2007 |
Persistent lactic acidosis in neonatal hypoxic-ischaemic encephalopathy correlates with EEG grade and electrographic seizure burden.
Topics: Acidosis, Lactic; Asphyxia Neonatorum; Electroencephalography; Female; Humans; Hypoxia-Ischemia, Bra | 2008 |
Prenatal cord clamping in newborn Macaca nemestrina: a model of perinatal asphyxia.
Topics: Animals; Animals, Newborn; Asphyxia; Brain; Disease Models, Animal; Electroencephalography; Erythrop | 2007 |
Normal and seizure levels of lactate, pyruvate and acid-soluble phosphates in the cerebellum and cerebrum.
Topics: Brain Chemistry; Cerebellum; Cerebrum; Humans; Lactic Acid; Phosphates; Pyruvic Acid; Seizures; Tele | 1949 |
Peripheral glucose metabolism is altered by epileptic seizures.
Topics: Acoustic Stimulation; Animals; Blotting, Western; Epilepsy, Reflex; Fructosephosphates; Glucose; Glu | 2008 |
An improved method for perfusion of the isolated brain of the rat-influence of perfusion conditions and application of analeptic and anticonvulsant drugs.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Brain; Central Nervous System Stimulants; Lactates | 1983 |
Brain metabolism during prolonged seizures in neonates.
Topics: Animals; Animals, Newborn; Blood Glucose; Brain; Glucose; Haplorhini; Humans; Infant, Newborn; Infan | 1983 |
[Effects of idebenone (CV-2619) on neurological deficits, local cerebral blood flow, and energy metabolism in rats with experimental cerebral ischemia].
Topics: Adenosine Triphosphate; Animals; Benzoquinones; Brain Ischemia; Cerebral Cortex; Cerebrovascular Cir | 1984 |
Optimizing the measurement of regional cerebral glucose consumption with [6-14C]glucose.
Topics: Animals; Autoradiography; Bicuculline; Blood Glucose; Brain; Carbon Dioxide; Carbon Radioisotopes; G | 1994 |
Cerebral energy state of neonatal rats during seizures induced by homocysteine.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Cerebral Cortex; Energy Metabolism; Glucose; Glyc | 1993 |
Infant onset subacute necrotizing encephalomyelopathy (Leigh's disease)
Topics: Apnea; Blindness; Female; Humans; Infant; Lactates; Lactic Acid; Leigh Disease; Male; Seizures | 1993 |
Immunohistochemical studies with antibodies to neurofilament proteins on axonal damage in experimental focal lesions in rat.
Topics: Animals; Axons; Biomarkers; Brain Injuries; Cerebral Infarction; Immunoenzyme Techniques; Lactates; | 1993 |
Temporal changes in proton MRS metabolites after kainic acid-induced seizures in rat brain.
Topics: Animals; Aspartic Acid; Brain; Cell Count; Choline; Creatinine; Dipeptides; Disease Models, Animal; | 1997 |
Cerebral metabolic changes in biotinidase deficiency.
Topics: Amidohydrolases; Biotin; Biotinidase; Brain; Electroencephalography; Humans; Infant; Lactic Acid; Ma | 1997 |
Lactate and pyruvate changes in the cerebral gray and white matter during posthypoxic seizures in newborn pigs.
Topics: Animals; Animals, Newborn; Cerebellum; Electroencephalography; Hypoxia; Lactic Acid; Microdialysis; | 1998 |
Carnitine-acylcarnitine translocase deficiency: metabolic consequences of an impaired mitochondrial carnitine cycle.
Topics: Ammonia; Cardiac Output, Low; Carnitine; Carnitine Acyltransferases; Cells, Cultured; Coma; Consangu | 2000 |
Peritoneal dialysis in an infant with type 1 diabetes and hyperosmolar coma.
Topics: Acidosis, Lactic; Dehydration; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Humans; Hypergl | 2001 |
NADH: sensor of blood flow need in brain, muscle, and other tissues.
Topics: Animals; Brain; Cytosol; Lactic Acid; Muscle Contraction; Muscles; NAD; Physical Conditioning, Anima | 2001 |
The lethal form of Cushing's in 7B2 null mice is caused by multiple metabolic and hormonal abnormalities.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Cause of Death; Corticosterone; Cushing Syndrom | 2002 |
Therapeutic effects of a ketogenic diet in Rett syndrome.
Topics: Ammonia; Blood Glucose; Child; Child, Preschool; Dietary Fats; Electroencephalography; Energy Intake | 1986 |
Generalized seizures deplete brain energy reserves in normoxemic newborn monkeys.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Bicuculline; Brain; Callitrichinae; Energy Metabo | 1988 |
Triple nuclear NMR studies of cerebral metabolism during generalized seizure.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain; Cats; Energy Metabolism; Lactates; La | 1988 |
In vivo 31P and in vitro 1H nuclear magnetic resonance study of hypoglycemia during neonatal seizure.
Topics: Animals; Animals, Newborn; Bicuculline; Brain; Cerebrovascular Circulation; Dogs; Glucose; Hemodynam | 1987 |
Glycerol as an indicator of lipid degradation in bicuculline-induced seizures and experimental cerebral ischemia.
Topics: Adenosine Triphosphate; Animals; Bicuculline; Cats; Female; Fluorometry; Glycerol; Ischemic Attack, | 1986 |
Brain metabolism after electroshock seizure in the neonatal dog: a [31P]NMR study.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Brain; Dogs; Electroshock; Energy Metabolism; Lac | 1987 |
Convulsions as the etiology of lactic acidosis in acute diazinon toxicity in rats.
Topics: Acidosis, Lactic; Acute Disease; Animals; Diazinon; Female; Glycogen; Insecticides; Lactates; Lactic | 1987 |