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d-alpha tocopherol and Seizures

d-alpha tocopherol has been researched along with Seizures in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199017 (45.95)18.7374
1990's1 (2.70)18.2507
2000's10 (27.03)29.6817
2010's9 (24.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Annoura, H; Imajo, S; Miyajima, A; Nakanishi, K; Takemoto, N; Tamura, S; Tamura-Horikawa, Y; Toba, T1
Albertini, MC; Ambrogini, P; Bartolini, D; Betti, M; Cuppini, R; Di Palma, M; Galati, C; Galli, F; Lattanzi, D; Minelli, A; Olivieri, F; Palma, E; Ruffolo, G; Saccomanno, S; Savelli, D; Torquato, P1
Al-Khalek, HAA; Khalifa, AE; Masoud, SI; Nagib, MM; Rahmo, RM; Sabri, NA; Tadros, MG1
Matthews, SA; Samson, KK; Simeone, KA; Simeone, TA1
Couto, GB; de Almeida, ER; Ishigami, AB; Rafael, KR1
Feng, D; Freitas, RM; Tomé, AR1
Ferreira, PM; Freitas, RM; Tomé, Ada R1
Costa, JP; de Freitas, RM; de Souza, GF; dos Santos, PS; Feng, D; Saldanha, GB; Tomé, Ada R1
Keilhoff, G; Krug, M; Rauca, C; Wiswedel, I; Zerbe, R1
Baghiu, BM; Burnham, WM; Lui, R; Ma, DW; Nylen, K; Taha, AY1
Agar, E; Ayyildiz, M; Yildirim, M1
Gulati, K; Ray, A; Vijayan, VK1
Lutz, J; Stark, M1
Colugnati, DB; Cysneiros, RM; de Lima, E; Ferrari, D; Ghazale, PP; Janjoppi, L; Pansani, AP; Scorza, FA; Sinigaglia-Coimbra, R1
Al Yacoub, ON; Alomari, MA; Alrabadi, NN; Alzoubi, KH; Banihani, SA; Hasan, ZA; Khabour, OF; Mayyas, FA1
Bal, R; Butterworth, PJ; Celik, O; Kutluhan, S; Naziroğlu, M; Uğuz, AC1
Bornkamm, GW; Carlson, BA; Conrad, M; Coppola, V; Hatfield, DL; Köhrle, J; Roth, S; Schmitz, D; Schomburg, L; Schweizer, U; Tessarollo, L; Winterer, J; Wirth, EK; Wozny, C1
DELGIUDICE, A1
HORTON, B; KANN, HE; MENGEL, CE; SMITH, W1
Chaudhry, N; Prakash, V; Puri, V; Tatke, M1
Akgul, S; Oztas, B; Seker, FB1
Higashi, A; Ikeda, T; Matsuda, I; Matsukura, M; Miyoshino, S; Ohtani, Y; Tamari, H1
Kryzhanovskiĭ, GN; Nikushkin, EV; Shandra, AA1
Godlevskiĭ, LS; Kryzhanovskiĭ, GN; Shandra, AA1
Rubin, JJ; Willmore, LJ2
Braslavskiĭ, VE; Kryzhanovskiĭ, GN; Nikushkin, EV1
Braslavskii, VE; Glebov, RN; Kryzhanovskii, GN; Nikushkin, EV1
Dettbarn, WD; Gupta, RC; Milatovic, D1
Ogunmekan, AO1
Bishai, A; Burnham, WM; Hwang, PA; Levy, SL1
Kryzhanovskiĭ, GN; Shandra, AA1
Edamatsu, R; Hiramatsu, M; Kohno, M; Mori, A1
Bordiukov, MM; Kryzhanovskiĭ, GN; Nikushkin, EV; Tupeev, IR1
Brotz, M; French, JH; Lubell, H; Moore, CL; Sherard, ES1
Della Cella, G1
Duffy, EJ; Horton, BD; Mengel, CE; Zirkle, LG1

Other Studies

37 other study(ies) available for d-alpha tocopherol and Seizures

ArticleYear
Discovery of (2S)-1-(4-amino-2,3,5- trimethylphenoxy)-3-[4-[4-(4- fluorobenzyl)phenyl]-1-piperazinyl]-2-propanol dimethanesulfonate (SUN N8075): a dual Na(+) and Ca(2+) channel blocker with antioxidant activity.
    Journal of medicinal chemistry, 2000, Sep-07, Volume: 43, Issue:18

    Topics: Acoustic Stimulation; Aniline Compounds; Animals; Anticonvulsants; Antioxidants; Calcium Channel Blockers; Cerebral Cortex; In Vitro Techniques; Lipid Peroxidation; Mice; Mice, Inbred DBA; Models, Molecular; Molecular Conformation; Neuroprotective Agents; Piperazines; Rats; Seizures; Sodium Channel Blockers

2000
Neurobiological Correlates of Alpha-Tocopherol Antiepileptogenic Effects and MicroRNA Expression Modulation in a Rat Model of Kainate-Induced Seizures.
    Molecular neurobiology, 2018, Volume: 55, Issue:10

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha-Tocopherol; Animals; Blood-Brain Barrier; Disease Models, Animal; Gene Expression Regulation; Inflammation; Kainic Acid; Male; MicroRNAs; Nerve Degeneration; Oocytes; Oxidative Stress; Rats, Sprague-Dawley; Receptors, GABA; Seizures; Status Epilepticus; Xenopus

2018
Molecular mechanisms of neuroprotective effect of adjuvant therapy with phenytoin in pentylenetetrazole-induced seizures: Impact on Sirt1/NRF2 signaling pathways.
    Neurotoxicology, 2018, Volume: 68

    Topics: alpha-Tocopherol; Animals; Anticonvulsants; Antioxidants; Brain; Inflammation; Male; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Pentylenetetrazole; Phenytoin; Rats, Wistar; Seizures; Signal Transduction; Sirtuin 1; Ubiquinone

2018
Targeting deficiencies in mitochondrial respiratory complex I and functional uncoupling exerts anti-seizure effects in a genetic model of temporal lobe epilepsy and in a model of acute temporal lobe seizures.
    Experimental neurology, 2014, Volume: 251

    Topics: Adenosine Triphosphate; alpha-Tocopherol; Animals; Ascorbic Acid; Disease Models, Animal; Electric Stimulation; Electroencephalography; Electron Transport Complex I; Epilepsy, Temporal Lobe; Hippocampus; Hydrogen Peroxide; In Vitro Techniques; Kainic Acid; Kv1.1 Potassium Channel; Mice; Mice, Knockout; Mitochondria; Pyruvic Acid; Reactive Oxygen Species; Respiration; Seizures

2014
Anxiolytic and anticonvulsant effects on mice of flavonoids, linalool, and alpha-tocopherol presents in the extract of leaves of Cissus sicyoides L. (Vitaceae).
    Journal of biomedicine & biotechnology, 2009, Volume: 2009

    Topics: Acyclic Monoterpenes; alpha-Tocopherol; Analysis of Variance; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Cissus; Flavonoids; Humans; Male; Mice; Monoterpenes; Plant Extracts; Plant Leaves; Seizures; Sleep

2009
The effects of alpha-tocopherol on hippocampal oxidative stress prior to in pilocarpine-induced seizures.
    Neurochemical research, 2010, Volume: 35, Issue:4

    Topics: alpha-Tocopherol; Animals; Catalase; Hippocampus; Lipid Peroxidation; Male; Oxidative Stress; Pilocarpine; Rats; Rats, Wistar; Seizures; Superoxide Dismutase

2010
Inhibitory action of antioxidants (ascorbic acid or alpha-tocopherol) on seizures and brain damage induced by pilocarpine in rats.
    Arquivos de neuro-psiquiatria, 2010, Volume: 68, Issue:3

    Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; Brain Damage, Chronic; Hippocampus; Male; Muscarinic Agonists; Neuroprotective Agents; Pilocarpine; Rats; Rats, Wistar; Seizures

2010
Oxidative stress in rat striatum after pilocarpine-induced seizures is diminished by alpha-tocopherol.
    European journal of pharmacology, 2011, Oct-01, Volume: 668, Issue:1-2

    Topics: alpha-Tocopherol; Animals; Behavior, Animal; Catalase; Lipid Peroxidation; Male; Neostriatum; Nitrites; Oxidative Stress; Pilocarpine; Rats; Rats, Wistar; Seizures; Superoxide Dismutase; Time Factors

2011
The role of superoxide dismutase and alpha-tocopherol in the development of seizures and kindling induced by pentylenetetrazol - influence of the radical scavenger alpha-phenyl-N-tert-butyl nitrone.
    Brain research, 2004, May-29, Volume: 1009, Issue:1-2

    Topics: alpha-Tocopherol; Analysis of Variance; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Convulsants; Cyclic N-Oxides; Disease Models, Animal; Drug Administration Schedule; Gentisates; Hydroxybenzoates; Kindling, Neurologic; Male; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Superoxide Dismutase; Time Factors

2004
Lack of benefit of linoleic and alpha-linolenic polyunsaturated fatty acids on seizure latency, duration, severity or incidence in rats.
    Epilepsy research, 2006, Volume: 71, Issue:1

    Topics: alpha-Linolenic Acid; alpha-Tocopherol; Animals; Anticonvulsants; Kindling, Neurologic; Linoleic Acids; Male; Pentylenetetrazole; Rats; Rats, Long-Evans; Seizures; Time Factors; Weight Gain

2006
The involvement of nitric oxide in the anticonvulsant effects of alpha-tocopherol on penicillin-induced epileptiform activity in rats.
    Epilepsy research, 2007, Volume: 73, Issue:2

    Topics: alpha-Tocopherol; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillins; Rats; Rats, Wistar; Seizures

2007
Free radicals and theophylline neurotoxicity : an experimental study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2007, May-30, Volume: 53, Issue:5

    Topics: alpha-Tocopherol; Aminophylline; Animals; Antioxidants; Arginine; Ascorbic Acid; Dose-Response Relationship, Drug; Female; Free Radicals; Male; Melatonin; Mice; Nervous System Diseases; NG-Nitroarginine Methyl Ester; Nitroglycerin; Phosphodiesterase Inhibitors; Reactive Nitrogen Species; Reactive Oxygen Species; Seizures; Superoxide Dismutase; Theophylline

2007
Administration of perfluorochemicals under hyperbaric oxygen pressure and treatment with free oxygen radical scavengers.
    Biomaterials, artificial cells, and artificial organs, 1988, Volume: 16, Issue:1-3

    Topics: alpha-Tocopherol; Animals; Ascorbic Acid; Blood Substitutes; Drug Combinations; Fluorocarbons; Free Radicals; Glutathione; Hydroxyethyl Starch Derivatives; Hyperbaric Oxygenation; Lung; Male; Methylprednisolone; Organ Size; Oxygen; Rats; Rats, Inbred Strains; Seizures; Tocopherols; Vitamin E

1988
Long-term monotherapy treatment with vitamin E reduces oxidative stress, but not seizure frequency in rats submitted to the pilocarpine model of epilepsy.
    Epilepsy & behavior : E&B, 2018, Volume: 88

    Topics: Analysis of Variance; Animals; Antioxidants; Biomarkers; Disease Models, Animal; Epilepsy; Hippocampus; Male; Oxidative Stress; Parvalbumins; Pilocarpine; Rats; Rats, Wistar; Seizures; Vitamin E

2018
Vitamin E modifies high-fat diet-induced reduction of seizure threshold in rats: Role of oxidative stress.
    Physiology & behavior, 2019, 07-01, Volume: 206

    Topics: Animals; Antioxidants; Biomarkers; Brain; Catalase; Diet, High-Fat; Disease Models, Animal; Glutathione; Male; Oxidative Stress; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Vitamin E

2019
Topiramate and vitamin e modulate the electroencephalographic records, brain microsomal and blood antioxidant redox system in pentylentetrazol-induced seizure of rats.
    The Journal of membrane biology, 2009, Volume: 229, Issue:3

    Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Electroencephalography; Fructose; Glutathione; Lipid Peroxidation; Male; Microsomes; Oxidation-Reduction; Oxidative Stress; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Topiramate; Vitamin E

2009
Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2010, Volume: 24, Issue:3

    Topics: Animals; Blotting, Western; Calbindin 2; Cell Differentiation; Cells, Cultured; Electrophysiology; Glutathione Peroxidase; Immunohistochemistry; Interneurons; Mice; Mice, Knockout; Nerve Degeneration; Parvalbumins; Phospholipid Hydroperoxide Glutathione Peroxidase; RNA, Transfer, Amino Acyl; S100 Calcium Binding Protein G; Seizures; Selenium; Selenoproteins; Vitamin E

2010
[LARGE DOSES OF VITAMIN E IN OPHTHALMOLOGIC AND CONVULSIVE DISORDERS].
    La Semana medica, 1964, Jan-30, Volume: 124

    Topics: Adolescent; Brain; Brain Damage, Chronic; Brain Diseases; Brain Injuries; Child; Humans; Infant; Intellectual Disability; Ophthalmology; Seizures; Vitamin E

1964
OXYGEN TOXICITY AND VITAMIN E.
    Aerospace medicine, 1964, Volume: 35

    Topics: Anemia; Anemia, Hemolytic; Animals; Atmospheric Pressure; Blood Chemical Analysis; Erythrocytes; Hemolysis; Hydrogen Peroxide; Hyperbaric Oxygenation; Lipid Metabolism; Mice; Oxygen; Oxygen Inhalation Therapy; Peroxides; Research; Seizures; Toxicology; Ultraviolet Rays; Vitamin E

1964
Isolated vitamin E deficiency with demyelinating neuropathy.
    Muscle & nerve, 2005, Volume: 32, Issue:2

    Topics: Adult; Biopsy; Demyelinating Diseases; Electrodiagnosis; Humans; Male; Muscle Weakness; Muscular Atrophy; Nerve Fibers, Myelinated; Neural Conduction; Peripheral Nerves; Peripheral Nervous System Diseases; Seizures; Somatosensory Disorders; Spinocerebellar Ataxias; Sural Nerve; Vitamin E; Vitamin E Deficiency

2005
Gender difference in the influence of antioxidants on the blood-brain barrier permeability during pentylenetetrazol-induced seizures in hyperthermic rat pups.
    Biological trace element research, 2007, Volume: 118, Issue:1

    Topics: Animals; Antioxidants; Blood-Brain Barrier; Convulsants; Female; Fever; Male; Neuroprotective Agents; Pentylenetetrazole; Permeability; Rats; Rats, Wistar; Seizures; Selenium; Sex Factors; Vitamin E

2007
Serum vitamin E concentration in patients with severe multiple handicaps treated with anticonvulsants.
    Pediatric pharmacology (New York, N.Y.), 1980, Volume: 1, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Disabled Persons; Electroencephalography; Humans; Seizures; Time Factors; Vitamin E; Vitamin E Deficiency

1980
[Antiepileptic effects of complex therapy with vitamins and anticonvulsant preparations (experimental findings)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Drug Therapy, Combination; gamma-Aminobutyric Acid; Mice; Niacinamide; Pantothenic Acid; Pentylenetetrazole; Phenobarbital; Pyridoxal Phosphate; Seizures; Vitamin E; Vitamins

1982
[Effect of vitamin preparations on epileptic activity].
    Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 98, Issue:8

    Topics: Animals; Drug Evaluation, Preclinical; Drug Therapy, Combination; Epilepsy; Kindling, Neurologic; Mice; Niacinamide; Pyridoxal Phosphate; Rats; Seizures; Vitamin E; Vitamins

1984
Antiperoxidant pretreatment and iron-induced epileptiform discharges in the rat: EEG and histopathologic studies.
    Neurology, 1981, Volume: 31, Issue:1

    Topics: Administration, Oral; Animals; Antioxidants; Cerebral Cortex; Electroencephalography; Ferrous Compounds; Humans; Injections, Subcutaneous; Iron; Rats; Seizures; Selenium; Vitamin E

1981
[Increase in the peroxidation of neuron membrane lipids, one of the pathogenetic mechanisms of epileptic activity].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:6

    Topics: Animals; Bemegride; Butylated Hydroxytoluene; Cerebral Cortex; Electroencephalography; Lipid Peroxides; Membrane Lipids; Penicillins; Rats; Seizures; Synaptosomes; Vitamin E

1981
Prevention of iron-induced epileptiform discharges in rats by treatment with antiperoxidants.
    Experimental neurology, 1980, Volume: 67, Issue:3

    Topics: Animals; Cerebral Cortex; Deferoxamine; Electroencephalography; Evoked Potentials; Ferrous Compounds; Rats; Seizures; Selenium; Vitamin E

1980
[Lipoperoxidation in the hyperactive focus of rat cerebral cortex].
    Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 89, Issue:1

    Topics: Animals; Cerebral Cortex; Epilepsy; Lipid Peroxides; Penicillins; Rats; Seizures; Synaptosomes; Vitamin E

1980
Nitric oxide modulates high-energy phosphates in brain regions of rats intoxicated with diisopropylphosphorofluoridate or carbofuran: prevention by N-tert-butyl-alpha-phenylnitrone or vitamin E.
    Archives of toxicology, 2001, Volume: 75, Issue:6

    Topics: Adenosine Triphosphate; Amygdala; Animals; Antioxidants; Brain; Carbofuran; Cerebral Cortex; Cholinesterase Inhibitors; Citrulline; Cyclic N-Oxides; Hippocampus; Insecticides; Isoflurophate; Male; Neuroprotective Agents; Nitric Oxide; Nitrogen Oxides; Phosphocreatine; Rats; Rats, Sprague-Dawley; Seizures; Time Factors; Vitamin E

2001
Vitamin E deficiency and seizures in animals and man.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1979, Volume: 6, Issue:1

    Topics: Animals; Child; Child, Preschool; Cholesterol; Epilepsy, Tonic-Clonic; Humans; Intellectual Disability; Rats; Seizures; Vitamin E; Vitamin E Deficiency

1979
The anticonvulsant effects of vitamin E: a further evaluation.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1992, Volume: 19, Issue:2

    Topics: Animals; Anticonvulsants; Electrophysiology; Electroshock; Epilepsy, Complex Partial; Ferrous Compounds; Hyperbaric Oxygenation; Kainic Acid; Kindling, Neurologic; Male; Penicillins; Rats; Seizures; Vitamin E

1992
[Effect of diazepam, carbamazepine, sodium valproate and their combinations with vitamin preparations on epileptic activity].
    Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 100, Issue:11

    Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Drug Therapy, Combination; Male; Niacinamide; Pentylenetetrazole; Pyridoxal Phosphate; Rats; Seizures; Valproic Acid; Vitamin E; Vitamins

1985
The possible involvement of free radicals in seizure mechanism.
    The Japanese journal of psychiatry and neurology, 1986, Volume: 40, Issue:3

    Topics: Ascorbic Acid; Biomechanical Phenomena; Biphenyl Compounds; Drugs, Chinese Herbal; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydrazines; Picrates; Plant Extracts; Seizures; Vitamin E

1986
[State of the antioxidant system during induction in rats of primary generalized epileptic activity].
    Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 100, Issue:11

    Topics: Animals; Bemegride; Brain; Glutathione Peroxidase; Glutathione Reductase; Male; Rats; Rats, Inbred Strains; Seizures; Superoxide Dismutase; Vitamin E

1985
Trichopoliodystrophy. I. Report of a case and biochemical studies.
    Archives of neurology, 1972, Volume: 26, Issue:3

    Topics: Amino Acids; Brain Chemistry; Brain Diseases; Cerebellum; Cerebral Cortex; Cerebrosides; Cholesterol; Electroencephalography; Glycogen; Growth Disorders; Hair; Humans; Infant; Male; Nerve Degeneration; Pedigree; Phenobarbital; Phenytoin; Phospholipids; Plasmalogens; Seizures; Ubiquinone; Vitamin E

1972
[Vitamins and pregnancy].
    Acta vitaminologica et enzymologica, 1967, Volume: 21, Issue:5

    Topics: Abortion, Spontaneous; Anemia, Hemolytic, Congenital; Animals; Ascorbic Acid; Ergocalciferols; Female; Humans; Hydrocephalus; Infant, Newborn; Infant, Newborn, Diseases; Jaundice, Neonatal; Maternal-Fetal Exchange; Osteomalacia; Pregnancy; Pregnancy, Prolonged; Pyridoxine; Rats; Scurvy; Seizures; Skull; Vitamin A; Vitamin B 12; Vitamin E; Vitamin K; Vitamins

1967
Studies of oxygen toxicity in the central nervous system.
    Aerospace medicine, 1965, Volume: 36, Issue:11

    Topics: Animals; Hyperbaric Oxygenation; Mice; Seizures; Vitamin E

1965