phenylalanine and Seizures

phenylalanine has been researched along with Seizures in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199035 (76.09)18.7374
1990's3 (6.52)18.2507
2000's5 (10.87)29.6817
2010's3 (6.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jayaprakash, P; Kieć-Kononowicz, K; Latacz, G; Nurulain, SM; Oz, M; Sadek, B; Szymańska, E1
Choudhary, AK; Lee, YY1
Jahan, K; Pillai, KK; Vohora, D1
Cao, W; Glushakov, AV; Martynyuk, AE; Mecca, AP; Seubert, CN; Shah, HP; Shi, P; Sumners, C1
Benninger, C; Blackburn, GL; Butchko, HH; Comer, CP; de Sonneville, LM; Geha, RS; Hertelendy, Z; Koestner, A; Leon, AS; Liepa, GU; Mayhew, DA; McMartin, KE; Mendenhall, CL; Munro, IC; Novotny, EJ; Renwick, AG; Schiffman, SS; Schomer, DL; Shaywitz, BA; Spiers, PA; Stargel, WW; Tephly, TR; Thomas, JA; Trefz, FK1
FULLER, JL; HUFF, SD1
GROVES, R; SCHLOESSER, PT1
Blau, N; Connolly, MB; Demos, MK; Hyland, K; Lillquist, Y; Makhseed, N; Vallance, HD; Waters, PJ1
Cheng, LY; Chiu, PC; Hsiao, KJ; Lee, NC; Liu, TT; Niu, DM1
Cui, D; Du, H; Shi, J; Zhang, Y1
Araki, M1
Gentz, J; Levy, L; Lindblad, B; Lindstedt, S; Shasteen, W; Zetterstrom, R1
Berlow, S; Fariello, RG; Gross, PT; Schuett, VE1
Humeniuk, RE; Ong, J; White, JM1
Clayton, BE; Smith, I; Wolff, OH1
Battistin, L; Lorenzi, AD; Varotto, M1
Caccia, S; Diomede, L; Guiso, G; Romano, M; Salmona, M; Sarati, S1
Caccia, S; Diomede, L; Guiso, G; Nava, S; Romano, M; Salmona, M1
Butler, IJ; Roongta, SM; Villasana, D; Williams, JC1
Levy, G; Zhi, JQ1
Sze, PY1
Maher, TJ; Wurtman, RJ1
Maher, TJ; Pinto, JM1
Maher, TJ1
Alexander, GJ; Kopeloff, LM2
O'Halloran, MT; Yu, JS1
Alexander, GJ; Alexander, RB; Kopeloff, LM1
Gallagher, BB4
Boggan, WO; Freedman, DX; Schlesinger, K1
Norton, PR1
Prakh'e, IB1
Schlesinger, K; Uphouse, LL1
Beck, SL; Capobianco, JO1
Stevenson, R1
Goldberg, ME; Salama, AI1
Little, JM; Oliver, JH; Pirch, JH1
Guroff, G; Prichard, JW1
Oksenkrug, GF; Samsonova, ML1
Richter, JJ; Wainer, A1
Gallagher, BB; Glaser, GH; Prichard, JW1
Ammaniti, M1
Griek, BJ; Schlesinger, K; Schreiber, RA1

Reviews

6 review(s) available for phenylalanine and Seizures

ArticleYear
Neurophysiological symptoms and aspartame: What is the connection?
    Nutritional neuroscience, 2018, Volume: 21, Issue:5

    Topics: Affect; Animals; Aspartame; Aspartic Acid; Brain; Cognitive Dysfunction; Disease Models, Animal; Dopamine; Free Radicals; Humans; Hydrocortisone; Migraine Disorders; Nervous System Diseases; Neurotransmitter Agents; Non-Nutritive Sweeteners; Norepinephrine; Oxidative Stress; Phenylalanine; Seizures; Serotonin; Sleep Initiation and Maintenance Disorders

2018
Aspartame: review of safety.
    Regulatory toxicology and pharmacology : RTP, 2002, Volume: 35, Issue:2 Pt 2

    Topics: Affect; Animals; Aspartame; Behavior; Brain Neoplasms; Cognition; Drug Evaluation, Preclinical; Drug Hypersensitivity; Electroencephalography; Endocrine System; Headache; Humans; Methanol; Phenylalanine; Product Surveillance, Postmarketing; Seizures; Sweetening Agents; Weight Loss

2002
Pharmacological effects of phenylalanine on seizure susceptibility: an overview.
    Neurochemical research, 1989, Volume: 14, Issue:2

    Topics: Animals; Aspartame; Dipeptides; Disease Models, Animal; Disease Susceptibility; Humans; Phenylalanine; Seizures

1989
Possible neurologic effects of aspartame, a widely used food additive.
    Environmental health perspectives, 1987, Volume: 75

    Topics: Animals; Aspartame; Brain; Dipeptides; Food Additives; Humans; Phenylalanine; Seizures

1987
Neurotoxicology of food additives.
    Neurotoxicology, 1986,Summer, Volume: 7, Issue:2

    Topics: Animals; Aspartame; Blood-Brain Barrier; Dietary Carbohydrates; Dietary Proteins; Dipeptides; Emotions; Female; Food Additives; Maximum Allowable Concentration; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred SHR; Seizures; Sleep Initiation and Maintenance Disorders; Tyrosine; United States; United States Food and Drug Administration

1986
Pyridoxine dependency and central nervous system excitability.
    Advances in biochemical psychopharmacology, 1972, Volume: 4

    Topics: Acoustic Stimulation; Aging; Aminobutyrates; Animals; Brain Chemistry; Drug Interactions; Electric Stimulation; Genotype; Mice; Mice, Inbred Strains; Norepinephrine; Pentylenetetrazole; Phenylalanine; Phenylalanine Hydroxylase; Physostigmine; Pyridoxine; Reserpine; Seizures; Serotonin; Tetrabenazine; Thiosemicarbazones

1972

Other Studies

40 other study(ies) available for phenylalanine and Seizures

ArticleYear
Phenylalanine derivatives with modulating effects on human α1-glycine receptors and anticonvulsant activity in strychnine-induced seizure model in male adult rats.
    Epilepsy research, 2017, Volume: 138

    Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Glycine; HEK293 Cells; Humans; Ligands; Male; Membrane Potentials; Microinjections; Neuroblastoma; Oocytes; Oxidopamine; Patch-Clamp Techniques; Phenylalanine; Rats; Rats, Wistar; Receptors, Glycine; Seizures; Strychnine; Transduction, Genetic; Xenopus laevis

2017
Parachlorophenylalanine-induced 5-HT depletion alters behavioral and brain neurotransmitters levels in 6-Hz psychomotor seizure model in mice.
    Fundamental & clinical pharmacology, 2017, Volume: 31, Issue:4

    Topics: Animals; Brain; Disease Models, Animal; Electroshock; gamma-Aminobutyric Acid; Glutamine; Male; Mice; Neurotransmitter Agents; Phenylalanine; Psychomotor Agitation; Seizures; Serotonin; Valproic Acid

2017
Efficacy of 3,5-dibromo-L-phenylalanine in rat models of stroke, seizures and sensorimotor gating deficit.
    British journal of pharmacology, 2009, Volume: 158, Issue:8

    Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Endothelin-1; Gait Disorders, Neurologic; Glutamic Acid; Male; Pentylenetetrazole; Phenylalanine; Rats; Rats, Sprague-Dawley; Reflex, Startle; Seizures; Stroke

2009
AUDIOGENIC SEIZURES, THE DILITE LOCUS, AND PHENYLALANINE HYDROXYLASE IN DBA/1 MICE.
    Science (New York, N.Y.), 1964, Apr-17, Volume: 144, Issue:3616

    Topics: Animals; Liver; Mice; Mice, Inbred DBA; Mixed Function Oxygenases; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Research; Seizures; Sound

1964
A STATE PROGRAM TO CONTROL PHENYLKETONURIA.
    The American journal of nursing, 1964, Volume: 64

    Topics: Adolescent; Blood; Child; Diet; Diet Therapy; Genetics, Medical; Humans; Infant; Intellectual Disability; Kansas; Mass Screening; Phenobarbital; Phenylalanine; Phenylketonurias; Phenytoin; Public Health Nursing; Seizures

1964
6-pyruvoyl-tetrahydropterin synthase deficiency with mild hyperphenylalaninemia.
    Annals of neurology, 2005, Volume: 58, Issue:1

    Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Cerebral Palsy; Child; Developmental Disabilities; Diagnostic Errors; Dopamine Agents; Female; Humans; Levodopa; Movement Disorders; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Seizures

2005
Long-term follow-up of Chinese patients who received delayed treatment for 6-pyruvoyl-tetrahydropterin synthase deficiency.
    Molecular genetics and metabolism, 2006, Volume: 87, Issue:2

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Asian People; Biopterins; Child; Child, Preschool; China; Female; Follow-Up Studies; Humans; Infant; Intellectual Disability; Levodopa; Male; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Seizures; Time Factors

2006
Insulin analogs with B24 or B25 phenylalanine replaced by biphenylalanine.
    Acta biochimica et biophysica Sinica, 2008, Volume: 40, Issue:2

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Circular Dichroism; Dimerization; Humans; In Vitro Techniques; Insulin; Mice; Mice, Inbred ICR; Phenylalanine; Protein Structure, Quaternary; Receptor, Insulin; Seizures; Spectrometry, Fluorescence; Structure-Activity Relationship; Swine

2008
[Neuropsychiatric study on the effects of low-phenylalanine diet in phenylketonuria. 1. Electroencephalography, convulsions, developmental index and associated personality changes with low-phenylalanine diet therapy for phenylketonuria].
    Nihon Shonika Gakkai zasshi. Acta paediatrica Japonica, 1966, Volume: 70, Issue:11

    Topics: Child; Child, Preschool; Diet Therapy; Electroencephalography; Female; Humans; Infant; Infant, Newborn; Intelligence; Male; Personality; Phenylalanine; Phenylketonurias; Seizures

1966
Dietary treatment in tyrosinemia (tyrosinosis). With a note on the possible recognition of the carrier state.
    American journal of diseases of children (1960), 1967, Volume: 113, Issue:1

    Topics: Amino Acid Metabolism, Inborn Errors; Carrier State; Child; Child, Preschool; Diet Therapy; Female; Growth; Humans; Kidney Diseases; Kidney Tubules; Male; Mixed Function Oxygenases; Phenylacetates; Phenylalanine; Seizures; Tyrosine

1967
EEG in phenylketonuria. Attempt to establish clinical importance of EEG changes.
    Archives of neurology, 1981, Volume: 38, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Electroencephalography; Evoked Potentials; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intellectual Disability; Phenylalanine; Phenylketonurias; Seizures

1981
The effects of GABAB ligands on alcohol withdrawal in mice.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:3

    Topics: Animals; Baclofen; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Ethanol; Female; GABA Antagonists; GABA-B Receptor Antagonists; Mice; Mice, Inbred C57BL; Organophosphorus Compounds; Phenylalanine; Receptors, GABA-B; Seizures; Substance Withdrawal Syndrome; Tremor

1994
New variant of phenylketonuria with progressive neurological illness unresponsive to phenylalanine restriction.
    Lancet (London, England), 1975, May-17, Volume: 1, Issue:7916

    Topics: Biopterins; Child; Child, Preschool; Deglutition Disorders; Dihydropteridine Reductase; Female; Humans; Infant; Intellectual Disability; Male; Neuromuscular Diseases; Phenylalanine; Phenylketonurias; Seizures; Tyrosine

1975
Amino acid uptake in vivo by the mouse brain and by various regions of the rabbit brain after drug-induced convulsions.
    Brain research, 1975, May-23, Volume: 89, Issue:2

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Biological Transport, Active; Blood-Brain Barrier; Brain; Caudate Nucleus; Cerebral Cortex; Histidine; Hypothalamus; Isoleucine; Male; Mesencephalon; Methionine; Mice; Pentylenetetrazole; Phenylalanine; Rabbits; Seizures; Taurine; Thalamus

1975
Effect of tyrosine on the potentiation by aspartame and phenylalanine of metrazol-induced convulsions in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:12

    Topics: Animals; Aspartame; Brain; Drug Interactions; Male; Pentylenetetrazole; Phenylalanine; Rats; Rats, Inbred Strains; Seizures; Tyrosine

1991
Interspecies and interstrain studies on the increased susceptibility to metrazol-induced convulsions in animals given aspartame.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:2

    Topics: Animals; Aspartame; Brain; Drug Synergism; Guinea Pigs; Kinetics; Male; Mice; Mice, Inbred DBA; Pentylenetetrazole; Phenylalanine; Rats; Rats, Inbred Strains; Seizures; Species Specificity; Tyrosine

1991
Neurological deterioration in adult phenylketonuria.
    Journal of inherited metabolic disease, 1989, Volume: 12, Issue:4

    Topics: Adolescent; Adult; Biogenic Amines; Biopterins; Brain; Diet Therapy; Humans; Magnetic Resonance Imaging; Male; Muscle Spasticity; Neopterin; Phenylalanine; Phenylketonurias; Seizures

1989
Aspartame and phenylalanine do not enhance theophylline-induced seizures in rats.
    Research communications in chemical pathology and pharmacology, 1989, Volume: 66, Issue:1

    Topics: Animals; Aspartame; Body Temperature; Body Weight; Dipeptides; Drug Interactions; Female; Phenylalanine; Rats; Rats, Inbred Strains; Seizures; Theophylline

1989
Administration of aspartame potentiates pentylenetetrazole- and fluorothyl-induced seizures in mice.
    Neuropharmacology, 1988, Volume: 27, Issue:1

    Topics: Animals; Aspartame; Dipeptides; Dose-Response Relationship, Drug; Drug Synergism; Flurothyl; Male; Mice; Pentylenetetrazole; Phenylalanine; Seizures; Tyrosine

1988
Mechanism of p-chlorophenylalanine-mediated increase in seizure susceptibility: inhibition by cerebellar ablation.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 139, Issue:2

    Topics: Adrenergic Agents; Animals; Brain Chemistry; Cerebellum; Fenclonine; Male; Pentylenetetrazole; Phenylalanine; Rats; Seizures; Serotonin

1972
Children of mothers with phenylketonuria.
    Lancet (London, England), 1970, Jan-31, Volume: 1, Issue:7640

    Topics: Adolescent; Adult; Child; Child, Preschool; Diet Therapy; Family Planning Services; Female; Growth Disorders; Heart Defects, Congenital; Heterozygote; Homozygote; Humans; Intellectual Disability; Male; Microcephaly; Middle Aged; Phenylalanine; Phenylketonurias; Seizures; Strabismus; Tyrosine

1970
Anticonvulsive effect of p-chlorophenylalanine in audiosensitive mice.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, Aug-01, Volume: 10, Issue:15

    Topics: Animals; Brain Chemistry; Fenclonine; Male; Mice; Phenylalanine; Seizures; Serotonin; Sound

1971
Amino acids and cerebral excitability.
    Journal of neurochemistry, 1969, Volume: 16, Issue:5

    Topics: Amino Acids; Ammonia; Animals; Brain; Central Nervous System Stimulants; Diet; Glutamates; Glutamine; Glycine; Leucine; Lysine; Male; Methionine; Phenylalanine; Rats; Seizures; Serine; Stimulation, Chemical; Time Factors; Tryptophan; Valine

1969
Genetics of audiogenic seizures. 3. Time response relationships between drug administration and seizure susceptibility.
    Life sciences. Pt. 1: Physiology and pharmacology, 1970, Jul-01, Volume: 9, Issue:13

    Topics: 5-Hydroxytryptophan; Age Factors; Animals; Brain; Brain Chemistry; Female; Hydrazines; Iproniazid; Male; Methyltyrosines; Mice; Norepinephrine; Phenylalanine; Reserpine; Seizures; Serotonin; Sound; Time Factors

1970
The effects of drugs on barbiturate withdrawal convulsions in the rat.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:10

    Topics: Animals; Barbiturates; Chlordiazepoxide; Chlorpromazine; Ethanol; Ethosuximide; Female; Humans; Hydrazines; Hypnotics and Sedatives; Meprobamate; Methyltyrosines; Monoamine Oxidase Inhibitors; Morphine; Phenylalanine; Primidone; Rats; Reserpine; Seizures; Serotonin; Substance Withdrawal Syndrome; Tryptophan

1970
Relationship of phenylalanine to seizure threshold during maturation.
    Journal of neurochemistry, 1970, Volume: 17, Issue:3

    Topics: Age Factors; Animals; Brain; Brain Chemistry; Central Nervous System Stimulants; Injections, Intraperitoneal; Male; Phenylalanine; Rats; Seizures; Tyrosine

1970
The influence of tyrosine, phenylpyruvate and vitamin B 6 upon seizure thresholds.
    Journal of neurochemistry, 1971, Volume: 18, Issue:6

    Topics: Amino Acids; Animals; Brain; Brain Chemistry; Central Nervous System Stimulants; Ethers; Fluorine; Male; Myoclonus; Phenylalanine; Phenylpyruvic Acids; Pyridoxal Phosphate; Pyridoxine; Rats; Seizures; Time Factors; Tyrosine

1971
[Effect of agents, changing the monoamine level, on audiogenic epileptic seizures in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 76, Issue:9

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Anticonvulsants; Brain; Depression, Chemical; Dihydroxyphenylalanine; Female; Male; Methyltyrosines; Methysergide; Nialamide; Norepinephrine; Phenylalanine; Rats; Reserpine; Seizures; Serotonin; Stimulation, Chemical

1973
Postnatal effects on some behavioral and neural parameters in mice treated with -2-thienylalanine in utero.
    Teratology, 1971, Volume: 4, Issue:3

    Topics: Animals; Body Weight; Brain; Cell Differentiation; Central Nervous System Diseases; Female; Humans; Learning Disabilities; Mice; Organ Size; Phenylalanine; Pregnancy; Seizures; Sound

1971
Microcephaly and mental retardation in offspring of a mother with phenylketonuria.
    Birth defects original article series, 1971, Volume: 7, Issue:1

    Topics: Child, Preschool; Female; Humans; Infant; Intellectual Disability; Male; Microcephaly; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Seizures

1971
Effect of alpha-methyltyrosine on stress-induced changes in seizure susceptibility.
    European journal of pharmacology, 1970, Volume: 9, Issue:2

    Topics: Animals; Brain Chemistry; Catecholamines; Chlorpromazine; Disulfiram; Male; Methyldopa; Methyltyrosines; Mice; Monoamine Oxidase Inhibitors; Phenylalanine; Reserpine; Seizures; Stress, Physiological; Tetrabenazine; Time Factors; Tyrosine

1970
Effect of reserpine and other drugs on the CNS and lethal effects of hyperbaric oxygen in mice.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 183, Issue:2

    Topics: Animals; Central Nervous System; Electroshock; Hyperbaric Oxygenation; Methods; Methyldopa; Methyltyrosines; Mice; Phenoxybenzamine; Phenylalanine; Phenytoin; Reserpine; Seizures; Tranylcypromine

1970
Metrazol seizures in rats: effect of p-chlorophenylalanine.
    Brain research, 1970, Aug-27, Volume: 22, Issue:2

    Topics: Animals; Male; Pentylenetetrazole; Phenylalanine; Rats; Seizures

1970
The relationships between phenylalanine, phenylpyruvate, vitamin B-6 and seizure threshold.
    Neurology, 1970, Volume: 20, Issue:4

    Topics: Drug Antagonism; Phenylalanine; Phenylpyruvic Acids; Pyridoxal Phosphate; Pyridoxine; Seizures; Time Factors

1970
Increased cerebral excitability caused by p-chlorophenylalanine in young rats.
    Journal of neurochemistry, 1971, Volume: 18, Issue:1

    Topics: Animals; Animals, Newborn; Brain; Brain Chemistry; Chlorine; Female; Injections, Intraperitoneal; Liver; Mixed Function Oxygenases; Phenylalanine; Rats; Seizures; Serotonin; Stimulation, Chemical

1971
[Role of central serotoninergic processes in the occurrence of the phenomenon of head shaking in mice and rats due to tryptophan].
    Biulleten' eksperimental'noi biologii i meditsiny, 1971, Volume: 72, Issue:7

    Topics: Animals; Brain; Bromine; Female; Lysergic Acid Diethylamide; Male; Methysergide; Mice; Phenelzine; Phenylalanine; Rats; Seizures; Serotonin; Serotonin Antagonists; Tryptophan

1971
Evidence for separate systems for the transport of neutral and basic amino acids across the blood-brain barrier.
    Journal of neurochemistry, 1971, Volume: 18, Issue:4

    Topics: Alanine; Amino Acids; Animals; Arginine; Biological Transport; Blood-Brain Barrier; Carbon Isotopes; Glycine; Injections, Intraperitoneal; Isoleucine; Lysine; Male; Mice; Phenylalanine; Rats; Seizures; Valine

1971
Seizure threshold and excess dietary amino acids.
    Neurology, 1968, Volume: 18, Issue:3

    Topics: Age Factors; Animals; Body Weight; Diet; Ethyl Ethers; Methionine; Myoclonus; Phenylalanine; Rats; Seizures; Tyrosine

1968
[Diagnostic problems in a dysphasic subject with an error of phenylalanine metabolism].
    Minerva pediatrica, 1968, Mar-10, Volume: 20, Issue:10

    Topics: Child, Preschool; Epilepsy; Humans; Infant; Intellectual Disability; Language Disorders; Male; Movement Disorders; Phenylalanine; Phenylketonurias; Seizures; Speech Disorders

1968
Effects of experimentally induced phenylketonuria on seizure susceptibility in mice.
    Journal of comparative and physiological psychology, 1969, Volume: 67, Issue:2

    Topics: Animals; Brain Chemistry; Diet; Humans; Mice; Norepinephrine; Phenylalanine; Phenylketonurias; Seizures; Serotonin; Tyrosine

1969